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*  Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells |...
Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells. V P ... Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells ... Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells ... Effects of pertussis toxin on adenylate cyclase responses to prostaglandin E2 and calcitonin in human breast cancer cells ...
http://www.biochemj.org/content/224/2/371
*  Detection of anti-pertussis toxin IgG in oral fluids for use in diagnosis and surveillance of Bordetella pertussis infection in...
Serum IgG titres against pertussis toxin (PT) are routinely used as a marker of recent or persisting B. pertussis infection. ... for pertussis amongst children with chronic coughs when used as a surrogate for the serum ELISA (assuming disease prevalence of ... Bordetella pertussis infection is being increasingly recognized as a cause of prolonged, distressing cough (without whooping ... 12-37%). This oral fluid ELISA will greatly assist in the convenience of B. pertussis disease diagnosis and surveillance. © ...
https://www.phc.ox.ac.uk/publications/214413
*  Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL-10 production and...
Ross, P.J., Lavelle, E.C., Mills, K.H.G. and A.P. Boyd `Adenylate cyclase toxin from Bordetella pertussis synergises with ... Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL-10 production and ... Adenylate cyclase toxin (CyaA) from Bordetella pertussis can subvert host immune responses allowing bacterial colonization. ... Adenylate Cyclase Toxin from Bordetella pertussis Synergizes with Lipopolysaccharide To Promote Innate Interleukin-10 ...
http://www.tara.tcd.ie/handle/2262/33327
*  Welcome to CDC stacks | Bordetella petrii Clinical Isolate - 15820 | Emerging Infectious Diseases
A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an ... Comparison with a French strain that was pertussis toxin-deficient, pertactin wil... ... The genomes of 9 clinical isolates show that they are clonal, lack the virulence factors encoded by B. pertussis, and are more ... An increasing number of pertussis-like cases are attributed to the emergent pathogen Bordetella holmesii. ...
https://stacks.cdc.gov/view/cdc/15820
*  Temporal Trends in Bordetella pertussis Populations, Denmark, 1949-2010 - Volume 18, Number 5-May 2012 - Emerging Infectious...
Our results show substantial shifts in the B. pertussis population over time and a reduction in genetic diversity. These ... to characterize isolates of Bordetella pertussis strains circulating in Denmark during periods with and without pertussis ... changes might have resulted from the introduction of pertussis vaccines in Denmark and other parts of Europe. The predominant ... pertussis toxin S1 subunit (ptxA, also designated ptxS1), B. pertussis toxin promoter (ptxP), and tracheal colonization factor ...
https://wwwnc.cdc.gov/eid/article/18/5/11-0812_article
*  "The effects of Bordetella pertussis on dendritic cell imprinting of CD" by Sana Waheed
One of the hallmarks of infection is lymphocytosis, which is induced by the pertussis toxin. Lymphocytes such as CD4+ T cells ... Imprinting levels on CD4+ T cells were compared to Bordetella parapertussis, a related strain that lacks pertussis toxin. Our ... We hypothesized that the pertussis toxin affects the imprinting process resulting in altered expression of trafficking ... However, 25 days post-infection with B. pertussis, dendritic cells continued to express elevated levels of MHC class II, and ...
http://scholarworks.sjsu.edu/etd_theses/3837/
*  Bordetella Pertussis Infections in Vaccinated and Unvaccinated Adolescents and Adults, as Assessed in a National Prospective...
Pertussis toxin antibody had the greatest specificity for detecting increases in antibody levels. Asymptomatic infections were ... Immunoglobulin G (IgG) and immunoglobulin A (IgA) antibodies to pertussis toxin, filamentous hemagglutinin, pertactin, and ... Acellular pertussis (aP) booster immunizations have been recommended for adolescents and older persons to enhance long-term ... Acellular pertussis (aP) booster immunizations have been recommended for adolescents and older persons to enhance long-term ...
http://oxfordindex.oup.com/view/10.1086/504803
*  The Lancet: [Articles] Cost-effectiveness of pre-exposure prophylaxis for HIV prevention in men who have sex with men...
... of our trial led to the licensure of new acellular pertussis vaccines containing genetically inactivated pertussis toxin in ... Comment] Acellular pertussis vaccines: where to go to?. Since their introduction in the 1940s and 1950s, pertussis vaccines ( ... vaccination.1 Pertussis vaccines come in two varieties: one is made of whole-cell killed Bordetella pertussis cells, ... The new TdaP(PTgen/FHA) vaccine is safe and induces higher pertussis responses 28 days after vaccination than does the ...
http://www.healthcareintheuk.co.uk/2017/10/the-lancet-articles-cost-effectiveness.html
*  Quantification of cell-associated and free antigens in Bordetella pertussis suspensions by antigen binding ELISA | Drug...
Therefore, ELISAs to quantify pertussis toxin (PT), filamentous haemagglutinin (FHA), 92 kD outer membrane protein (92 kD-OMP) ... toxin; vaccine Abstract:. In order to achieve batch-to-batch consistency of whole-cell pertussis vaccines, properties relevant ... and pertactin (PRN) in Bordetella pertussis (B. pertussis) suspensions were developed. In this paper the influence of the ... antigen binding elisa; whole-cell pertussis vaccine; antigen density; biomass; growth phase; outer-membrane protein; ...
http://drugdeliverytechnology.leidenuniv.nl/publications/3144
*  The primary and secondary cellular immune responses to whole cell Bordetella pertussis vaccine and its components
Barry, E.M.; Levine, M.M., 1998: Immune responses to the Bordetella pertussis antigens pertactin and pertussis toxin expressed ... Thomas M.G.; Ashworth L.A.E.; Miller E.; Lambert H.P., 1989: Serum igg iga and igm responses to pertussis toxin filamentous ... Thomas, M.G.; Ashworth, L.A.; Miller, E.; Lambert, H.P., 1989: Serum IgG, IgA, and IgM responses to pertussis toxin, ... The use of purified materials confirmed that the presence of this pertussis toxin (PT) was responsible for the later peak in ...
https://eurekamag.com/research/006/740/006740700.php
*  Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of...
Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ... Humans infected with Bordetella pertussis, the whooping cough bacterium, show evidences of impaired host defenses. This ... which suggests the mounting of an anti-toxin cell repair-response, very likely involving the toxin elimination from the cell ... Ca2 Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin ACT Endocytosis. Cell Physiology and Expression of ...
http://libros.duhnnae.com/2017/jun8/149829571451-Ca2-Influx-and-Tyrosine-Kinases-Trigger-Bordetella-Adenylate-Cyclase-Toxin-ACT-Endocytosis-Cell-Physiology-and-Expression-of-the-CD11b-CD18-Integrin.php
*  DTP Vaccine, DTP,diphtheria,tetanus,pertussis vaccination schedule, DTP vaccine risk,DTP vaccine side effects - Parenting...
... pertussis, DTP vaccine effectiveness why DTP vaccine is necessary, side effects of DTP vaccine,DTP vaccine schedule in India. ... Tetanus (lockjaw): It is a nerve disease that can happen at any age and is caused by a toxin-producing bacteria that ... Pertussis (whooping cough): It is a respiratory illness which has cold symptoms which further progress to serious coughing. ... The DTP stands for diphtheria, tetanus, and pertussis. This vaccine protects the child against:. Diphtheria: A severe throat ...
http://www.parentingnation.in/vaccination/dtp-vaccine_1432
*  Pertussis toxin is required for pertussis vaccine encephalopathy | PNAS
Pertussis toxin is required for pertussis vaccine encephalopathy. L Steinman, A Weiss, N Adelman, M Lim, R Zuniga, J Oehlert, E ... Pertussis toxin is required for pertussis vaccine encephalopathy. L Steinman, A Weiss, N Adelman, M Lim, R Zuniga, J Oehlert, E ... Pertussis toxin is required for pertussis vaccine encephalopathy. L Steinman, A Weiss, N Adelman, M Lim, R Zuniga, J Oehlert, E ... Two lines of evidence implicate pertussis toxin as the active bacterial component. Single-site mutants of B. pertussis with ...
https://www.pnas.org/content/82/24/8733.long
*  Browsing by Subject "Pertussis Toxin"
The mechanism of mitogen-activated protein (MAP) kinase activation by pertussis toxin-sensitive Gi-coupled receptors is known ...
https://dukespace.lib.duke.edu/dspace/browse?type=subject&value=Pertussis%20Toxin
*  Anti-Bordetella pertussis toxin subunit S2 antibody [20.6] (ab27158) | Abcam
Mouse monoclonal Bordetella pertussis toxin subunit S2 antibody [20.6]. Validated in WB, ELISA. Cited in 1 publication(s). ... Pertussis toxin (islet activating protein) is the major protein toxin produced by virulent strains of Bordetella pertussis. As ... The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine ... Reacts with the intact toxin as well as the S2 subunit. Some reactivity towards the toxoid is also present. ...
https://www.abcam.com/bordetella-pertussis-toxin-subunit-s2-antibody-206-ab27158.html
*  Mutants of pertussis toxin suitable for vaccine development | Science
... inactive toxins were constructed by genetic manipulation. A number of genetically engineered alleles of the pertussis toxin ... Mutants of pertussis toxin suitable for vaccine development. By M Pizza, A Covacci, A Bartoloni, M Perugini, L Nencioni, MT De ... Mutants of pertussis toxin suitable for vaccine development. By M Pizza, A Covacci, A Bartoloni, M Perugini, L Nencioni, MT De ... Mutants of pertussis toxin suitable for vaccine development Message Subject. (Your Name) has forwarded a page to you from ...
https://science.sciencemag.org/content/246/4929/497.abstract
*  Pertussis toxin - Wikipedia
Carbonetti NH (2010). "Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell ... "Pertussis toxin and the adenylate cyclase toxin from Bordetella pertussis activate human monocyte-derived dendritic cells and ... Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping ... "Pertussis Toxin Plays an Early Role in Respiratory Tract Colonization by Bordetella pertussis". Infect. Immun. 71 (11): 6358-66 ...
https://en.wikipedia.org/wiki/Pertussis_toxin
*  Pertussis Toxin and Virulence Factors, List Biological | VWR
Bordetella pertussis, is a multi-subunit toxin which binds to most cultured mammalian cells and targets specific G protein ... Pertussis toxin (PT), a virulence factor produced by ...
https://us.vwr.com/store/product/17442048/pertussis-toxin-pt-a-virulence-factor-produced-by-i-bordetella-pertussis-i-is-a-multi-subunit-toxin-which-binds-to-most-cultured-mammalian-cell
*  Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes | Blood Journal
Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes. AW Gagnon, DR ... Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes. Blood, 78(5), 1247 ... Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes ... Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes ...
http://www.bloodjournal.org/content/78/5/1247?ijkey=153cccae698994d99b86eaecbdd5268b605558ae&keytype2=tf_ipsecsha&sso-checked=true
*  Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a...
Membrane localization of the pertussis toxin-sensitive G-protein subunits αi-2 and αi-3 and expression of a metallothionein-αi- ... Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a ... Membrane localization of the pertussis toxin-sensitive G-protein subunits αi-2 and αi-3 and expression of a metallothionein-αi- ... Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a ...
http://www.pnas.org/content/87/12/4635.long
*  WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins. | Masarykova univerzita
Zde se nacházíte: Masarykova univerzita Výzkum Publikace WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive ... WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins.. Autoři. KILANDER Michaela ... which is sensitive to pertussis toxin, thus implicating the involvement of heterotrimeric G proteins of the G(i/o) family. We ... to show that WNT-5A stimulation of N13 membranes and permeabilized cells evokes the exchange of GDP for GTP of pertussis toxin- ...
https://www.muni.cz/vyzkum/publikace/929234
*  ptxB - Pertussis toxin subunit 2 precursor - Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) - ptxB gene &...
sp,P04978,TOX2_BORPE Pertussis toxin subunit 2 OS=Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) OX=257313 ... Pertussis toxin subunit 2Add BLAST. 199. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical view ... Belongs to the pertussis toxin S2/S3 subunits family.Curated. Keywords - Domaini. Signal. Phylogenomic databases. The HOGENOM ... Pertussis toxin contains five different chains, S1-S5. They are organized into 2 functional subunits: A, composed of S1 (which ...
https://www.uniprot.org/uniprot/P04978
*  Pertussis Toxin-Sensitive G Protein Mediation of PGE2 Inhibition of cAMP Metabolism and Phasic Glucose-Induced Insulin...
Pretreatment with pertussis toxin partly prevented PGE2 inhibition to 80 ± 4% of controls for first phase and 79 ± 4% of ... Pertussis Toxin-Sensitive G Protein Mediation of PGE2 Inhibition of cAMP Metabolism and Phasic Glucose-Induced Insulin ... Pertussis Toxin-Sensitive G Protein Mediation of PGE2 Inhibition of cAMP Metabolism and Phasic Glucose-Induced Insulin ... Pertussis Toxin-Sensitive G Protein Mediation of PGE2 Inhibition of cAMP Metabolism and Phasic Glucose-Induced Insulin ...
http://diabetes.diabetesjournals.org/content/38/11/1439
*  Activation of M3 muscarinic receptors inhibits T-type Ca(2+) channel currents via pertussis toxin-sensitive novel protein...
Intracellular infusion of GDP-β-S or pretreatment of the cells with pertussis toxin (PTX) completely blocked the inhibitory ... Activation of M3 muscarinic receptors inhibits T-type Ca(2+) channel currents via pertussis toxin-sensitive novel protein ...
https://www.sigmaaldrich.com/catalog/papers/21329754
*  CCR1-Mediated STAT3 Tyrosine Phosphorylation and CXCL8 Expression in THP-1 Macrophage-like Cells Involve Pertussis Toxin...
CCR1 was demonstrated to use pertussis toxin-insensitive Gα14/16 to stimulate phospholipase Cβ and NF-κB, whereas both Gα14 and ... CCR1-mediated activation of Nuclear Factor-kappaB in THP-1 monocytic cells involves Pertussis Toxin-insensitive Galpha(14) and ... CCR1-Mediated STAT3 Tyrosine Phosphorylation and CXCL8 Expression in THP-1 Macrophage-like Cells Involve Pertussis Toxin- ... CCR1-Mediated STAT3 Tyrosine Phosphorylation and CXCL8 Expression in THP-1 Macrophage-like Cells Involve Pertussis Toxin- ...
http://www.jimmunol.org/content/189/11/5266.full