Proteopedia Peroxisome_Proliferator-Activated_Receptors - the Peroxisome Proliferator-Activated Receptor Structure in ... In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor ... "The peroxisome proliferator-activated receptor: A family of nuclear receptors role in various diseases". J Adv Pharm Technol ... peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions". Prog. Lipid Res ...
Rather, the peroxisome proliferator-activated receptor α (PPARα) and other nuclear receptors have been identified as key ... Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis. John J. Lehman,1 Philip M ... The peroxisome proliferator activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl ... A critical role for the peroxisome proliferator-activated receptor alpha (PPARα) in the cellular fasting response: the PPARα- ...
... death receptor 5 (DR5). In the present study, we showed that co-treatment with troglitazone (TGZ), … ... to cause apoptosis in several types of malignant tumor cells through its interaction with the death domain-containing receptor ... Peroxisome proliferator-activated receptor γ ligand troglitazone and TRAIL synergistically induce apoptosis Oncol Rep. 2014 Feb ... a synthetic ligand of peroxisome proliferator-activated receptor γ (PPARγ), and TRAIL synergistically induced apoptosis through ...
Tyagi S, Gupta P, Saini AS, Kaushal C, Sharma S. The peroxisome proliferator-activated receptor: A family of nuclear receptors ... Peroxisome proliferator-activated receptors. Pharmacol Rev. 2006;58:726-741. [PubMed] [DOI] [Cited in This Article: ] [Cited by ... p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes. 2006;55:2562-2570. [ ... Figure 3 Activation of peroxisome proliferator-activated receptors α and associated biological response in adipose tissue. TNF- ...
Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability. Peter M. Masschelin ... Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability ... Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability ... Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability ...
Inhibition of Aldose Reductase Activates Hepatic Peroxisome Proliferator-Activated Receptor-α and Ameliorates Hepatosteatosis ... L. Qiu, X. Wu, J. F. L. Chau et al., "Aldose reductase regulates hepatic peroxisome proliferator-activated receptor α ... is highly responsive to peroxisome proliferator-activated receptor α activators," Journal of Biological Chemistry, vol. 278, no ... "A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor α-deficient ...
We studied binding of ligands from different wines to the peroxisome proliferator-activated receptor γ (PPARγ), a ... for peroxisome proliferator-activated receptor γ A. Zoechling, F. Liebner and A. Jungbauer, Food Funct., 2011, 2, 28 DOI: ... from different wines to the peroxisome proliferator-activated receptor γ (PPARγ), a key factor in glucose. and lipid. ... A source of potent ligands for peroxisome proliferator-activated receptor γ Alfred Zoechling,ab Falk Liebnerc and Alois ...
Interaction of the peroxisome-proliferator-activated receptor and retinoid X receptor. Proc Natl Acad Sci USA. 1993;90:1440- ... p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes. 2006;55:2562-2570. [ ... Peroxisome proliferator activated receptor-alpha expression in human liver. Mol Pharmacol. 1998;53:14-22. [PubMed] [DOI] [Cited ... The peroxisome proliferator activated receptor regulates malic enzyme gene expression. J Biol Chem. 1994;269:26754-26758. [ ...
Peroxisome proliferator-activated receptor γ contributes to T lymphocyte apoptosis during sepsis. Journal of Leukocyte Biology ... Peroxisome proliferator-activated receptor γ contributes to T lymphocyte apoptosis during sepsis. In: Journal of Leukocyte ... Peroxisome proliferator-activated receptor γ contributes to T lymphocyte apoptosis during sepsis. / Soller, M; Tautenhahn, A; ... title = "Peroxisome proliferator-activated receptor γ contributes to T lymphocyte apoptosis during sepsis", ...
With regard to energy homoeostasis, PGC-1α (peroxisome-proliferator-activated receptor γ co-activator-1α, encoded by the ... Placental DNA methylation of peroxisome-proliferator-activated receptor-γ co-activator-1α promoter is associated with maternal ... Placental DNA methylation of peroxisome-proliferator-activated receptor-γ co-activator-1α promoter is associated with maternal ...
CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver. Ngome L. Makia and Joyce A. Goldstein ... Hypolipidemic drugs, such as bezafibrate, known activators of the peroxisome proliferator-activated receptor α (PPARα), induce ... CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver ...
The nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) helps to translate what you eat into what you are ...
Members of the peroxisome proliferator-activated receptor (PPAR) family might be involved in pathologies with altered lipid ... peroxisome proliferator-activated receptor; RT, reverse transcription; RXR, retinoic X receptor. ... Members of the peroxisome proliferator-activated receptor (PPAR) family might be involved in pathologies with altered lipid ... Tissue Distribution and Quantification of the Expression of mRNAs of Peroxisome Proliferator-Activated Receptors and Liver X ...
Many of these contaminants act via the activation (i.e. agonism) of the peroxisome proliferator activated receptor γ (PPAR ... Characterizing the Binding Potential, Activity, and Bioaccessibility of Peroxisome Proliferator Activated Receptor Gamma (PPAR ... Proliferator Activated Receptor Gamma (PPARγ) Ligands in Indoor Dust. Dissertation, Duke University. Retrieved from https ... In addition, chemical mixtures in house dust can effectively bind to and activate PPAR. However, our results suggest ...
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear receptors that regulate gene transcription, ... a peroxisome proliferator-activated receptor-γ, inhibits the Jun NH2-terminal kinase/activating protein 1 pathway and protects ... Takano H, Nagai T, Asakawa M, Toyozaki T, Oka T, Komuro I, Saito T, Masuda Y: Peroxisome proliferator-activated receptor ... Qi C, Zhu Y, Reddy JK: Peroxisome proliferator-activated receptors, coactivators, and downstream targets. Cell Biochem Biophys ...
C-reactive protein; Lipoprotein lipase; Peroxisome proliferator-activated receptor; Type 2 diabetes mellitus; Insulin receptor ... The Genetics of Insulin Resistance: Analysis of the Peroxisome Proliferator-Activated Receptor Pathway ... Boudreaux, Monique Yvonne (2005) The Genetics of Insulin Resistance: Analysis of the Peroxisome Proliferator-Activated Receptor ... risk measures were the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) single nucleotide polymorphism (SNP) P12A ...
Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as candidates for the therapy of the metabolic ... Synthetic and natural Peroxisome Proliferator- Activated Receptor (PPAR) agonists as candidates for the therapy of the ... INTRODUCTION: Peroxisome proliferator-activated receptors (PPARs) are the molecular targets of hypolipidemic and insulin- ... Tan, C. K., Zhuang, Y., & Wahli, W. (2017). Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as ...
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA IS ESSENTIAL FOR CARDIAC ADAPTATION TO CHRONIC HYPOXIA ... PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA IS ESSENTIAL FOR CARDIAC ADAPTATION TO CHRONIC HYPOXIA ...
Many of these contaminants act via the activation of the peroxisome proliferator-activated receptor γ (PPARγ) nuclear receptor. ... Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame ... "Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame ... Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame ...
Human Peroxisome Proliferator Activated Receptor beta,PPAR-β ELISA Kit. All. Elisa Kit (11.192). Laboratuvar Cihazları (88). ... Human Peroxisome Proliferator Activated Receptor beta,PPAR-β ELISA Kit. Teklif Sepetine Ekle ...
Hypoxia modulation of peroxisome proliferatoractivated receptors (PPARs) in human glioblastoma stem cells. Implications for ... Hypoxia modulation of peroxisome proliferatoractivated receptors (PPARs) in human glioblastoma stem cells. Implications for ...
EXPRESSION OF PEROXISOME-PROLIFERATOR ACTIVATED RECEPTORS- IN DIABETICS, OBESE AND NORMAL SUBJECTS Authors. * Naeema Afzal ... Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator-activated receptor α mediates the ... An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol ... Peroxisome proliferator-activated receptors and the metabolic syndrome. Physiol Behav 2008;94(2):187-97. ...
N2 - Peroxisome proliferator-activated receptor α (PPARα) mediates the effects of foreign chemical peroxisome proliferators on ... AB - Peroxisome proliferator-activated receptor α (PPARα) mediates the effects of foreign chemical peroxisome proliferators on ... Peroxisome proliferator-activated receptor α (PPARα) mediates the effects of foreign chemical peroxisome proliferators on liver ... "Peroxisome proliferator-activated receptor α (PPARα) mediates the effects of foreign chemical peroxisome proliferators on liver ...
... is a ligand-activated transcription factor of the nuclear receptor superfamily that is involved in lipid and carbohydrate ... Introduction: Peroxisome proliferator-activated receptor γ (PPARγ) ... Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor of the nuclear receptor ... Gestational diabetes mellitus is associated with increased leukocyte peroxisome proliferator-activated receptor γ expression ...
PPARγTooltip Peroxisome proliferator-activated receptor gamma. *Agonists: 5-Oxo-ETE ... Receptor/signaling modulators. GABA receptor modulators. GABAA receptor positive modulators. Ionotropic glutamate receptor ... "Peroxisome Proliferator-activated Receptor γ (PPARγ) as a Molecular Target for the Soy Phytoestrogen Genistein". Journal of ... "Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): A review". Biochemical Pharmacology. 92 ( ...
The three peroxisome-proliferator-activated receptor (PPAR) subtypes PPAR-alpha, PPAR-gamma, and PPAR-delta are ligand- ... PPARs form obligate heterodimers with the retinoid X receptor, which bind to peroxisome-proliferator-response elements (PPREs ... Targeting components of the stress system as potential therapies for the metabolic syndrome - The peroxisome-proliferator- ... activated transcription factors of the nuclear receptor family. ... metabolic syndrome has focused attention on nuclear receptors, ...
The peroxisome proliferator activated receptor gamma co-activator 1 alpha (PGC1α) is an inducible transcriptional co-activator ... The peroxisome proliferator activated receptor gamma co-activator 1 alpha (PGC1α) is an inducible transcriptional co-activator ... Garlic-derived diallyl disulfide modulates peroxisome proliferator activated receptor gamma co-activator 1 alpha in ...
... and activation of peroxisome proliferator-activated receptors, which play a major role in adipocyte differentiation and energy ...
Intriguingly, a binary mixture of PFOA and the non-activating PFOS produced a higher activation of gmPpara1 compared to PFOA ... alone, suggesting that PFOS has a potentiating effect on receptor activation. Supporting the experimental data, docking and ... activate gmPpara1 in vitro, which was also supported by in silico analyses. ... has been linked to activation of peroxisome proliferator-activated receptors (Ppar) in many vertebrates. Here, we present the ...
... suggesting that CYP39A1 expression is activated by RORα nuclear receptors. This may provide a way to increase CYP39A1 activity ... We examined the role of transcriptional regulation by retinoic acid receptor-related orphan receptor α (RORα), a nuclear ... receptor that responds to oxysterol ligands. In humans, the promoter and first intronic regions of CYP39A1 contain two putative ... Treatment with the thiazolidinedione class of peroxisome proliferator-activated receptor gamma (PPARγ) agonists, widely ...