WikiGenes - AC1L2HRB - trimethyltin
Peripheral and central nervous system lesions caused by triethyl- and trimethyltin salts in rats. OShaughnessy, D.J., Losos, G ... Snn is localized in tissues with known sensitivity to trimethyltin (TMT), including the central nervous system, immune system, ... Trimethyltin (TMT) selectively damages neurons in rodent and human central nervous system after a single exposure [24]. ... protein glial fibrillary acidic protein are associated with chemical-induced injury to the rat central nervous system. Brock, T ...
WikiGenes - dioxidenium - oxooxidanium
Carbon monoxide, formed from HO2, is a putative neurotransmitter in the brain and peripheral autonomic nervous system [4]. ... In the nervous system CO is formed by a subtype of heme oxygenase (HO) designated HO2 [5]. ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...
WikiGenes
Glutamate is the major excitatory neurotransmitter in the central nervous system, and evidence for peripheral glutamatergic ... However, glutamate receptors have been identified in peripheral organs, including taste buds, myenteric plexus, and pancreatic ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...
WikiGenes - AC1L1A6Q - 6-[2-[(4-amino-4-carboxy-butanoyl)amino]-2...
Leukotrienes in the rat central nervous system. Lindgren, J.A., Hökfelt, T., Dahlén, S.E., Patrono, C., Samuelsson, B. Proc. ... Human peripheral blood basophils primed by interleukin 3 (IL-3) produce IL-4 in response to immunoglobulin E receptor ... Leukotriene C4- and D4-induced diffuse peripheral constriction of swine coronary artery accompanied by ST elevation on the ... Leukotriene C4- and D4-induced diffuse peripheral constriction of swine coronary artery accompanied by ST elevation on the ...
WikiGenes
Although ghrelin acts as a modulator of feeding behavior and energy metabolism in the central nervous system, recent studies ... Thus, ghrelin may act as a peripheral factor to avoid the excess metabolic demands imposed by pregnancy during malnutritional ... have implicated the peripheral actions of ghrelin in reproductive tissues. Here, we investigated the expression of ghrelin and ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...
WikiGenes - Atp6v0d2 - ATPase, H+ transporting, lysosomal V0...
A novel putative M9.2 isoform of V-ATPase expressed in the nervous system. Ueda, T., Ugawa, S., Shimada, S. Neuroreport (2003) ... Cysteine-directed cross-linking to subunit B suggests that subunit E forms part of the peripheral stalk of the vacuolar H+- ... A novel putative M9.2 isoform of V-ATPase expressed in the nervous system [11]. ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...
WikiGenes - MAGEL2 - MAGE-like 2
Magel2 distribution partially overlaps that of NDN:, with strong expression being detected in the central nervous system in mid ... More importantly, with the availability of maternal peripheral blood lymphocyte sample, we demonstrated that the maternal ... MAGEL2 is imprinted with monoallelic expression in control brain, and paternal-only expression in the central nervous system as ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...
WikiGenes - Trpv1 - transient receptor potential cation...
... in the nervous and cardiovascular systems [8].. *The cloned capsaicin receptor, also known as the vanilloid receptor subtype 1 ... The distribution of VR1 receptors in peripheral and central processes of rat primary vagal afferent neurons innervating the ... but the involvement of other receptor systems has not been elucidated [22]. ... evidence for functional capsaicin receptor expression and calcitonin gene-related peptide exocytosis in isolated peripheral ...
WikiGenes - Neurologic Manifestations
HIV in central nervous system and behavioral development: an HIV-2287 macaque model of AIDS. Kinman, L.M., Worlein, J.M., Leigh ... Uncoupling protein 2 promoter polymorphism -866G/A affects peripheral nerve dysfunction in Japanese type 2 diabetic patients. ... These findings suggest that increased tryptophan and 5-hydroxytryptamine in the nervous system may be responsible for the ... Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central nervous system that can result in ...
WikiGenes - Adiuretin - 1-[[10-(2-aminocarbonylethyl)-7...
Desmopressin might also act on extrarenal targets such as the central nervous system [8]. ... Gradients of inferior petrosal sinus (IPS) to peripheral (IPS/P) ACTH were calculated before and after stimulation with CRH ... accompanied by a persistent microvascular obstruction and a pronounced increase in the peripheral resistance (PRU) [22]. ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...
WikiGenes - IL1B - interleukin 1, beta
Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in ... Leukocyte activation in the peripheral blood of patients with cirrhosis of the liver and SIRS. Correlation with serum ... Among the IL-1 beta- and IL-6-positive CSF were eight of 15 HIV-1 patients with no clinical signs of central nervous system ... and crystallization of human interleukin-1 beta converting enzyme derived from an Escherichia coli expression system. ...
WikiGenes - Rag1 - recombination activating gene 1
The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Chun, J.J., Schatz, D.G ... A congenic strain (called ZORI here) with defects in Rag1 and Rag2 expression, thymocyte maturation and peripheral T cell ... Interaction between the innate and adaptive immune systems is required to survive sepsis and control inflammation after injury. ... Rag1 (-/-) C57BL/6 mice (Rag1), which lack an adoptive immune system, and immune-sufficient wild-type (WT) C57BL/6 mice ...
WikiGenes - Capoten - (2S)-1-[(2R)-2-methyl-3-sulfanyl...
To clarify the relationship between the renin-angiotensin axis and sympathetic nervous system in the accelerated hypertensives ... In a six month placebo-controlled cross-over trial twenty patients with hypertension and peripheral arterial disease were ... Role of the endogenous kallikrein-kinin system in modulating vasopressin-stimulated water flow and urea permeability in the ... suggesting a possible role of the immune system in captopril-mediated disease modulation [34]. ...
WikiGenes - Pluripotent Stem Cells
TGF alpha induces the proliferation and differentiation of central nervous system (CNS) astrocytes and pluripotent stem cells, ... CD34+ CD90+ cells and late hematopoietic reconstitution after autologous peripheral blood stem cell transplantation. Shimazaki ... The effect of lithium on murine hematopoiesis in a liquid culture system. Levitt, L.J., Quesenberry, P.J. N. Engl. J. Med. ( ... valuable for mobilizing pluripotent stem cells with long-term repopulating activity from the bone marrow to the peripheral ...
WikiGenes - Gene Expression Regulation
... that methylation-dependent regulation of gene expression may have a crucial role in the mammalian central nervous system [25]. ... intensity and sharpness of the peripheral staining for H4.Ac5-12, and (3) relative rate of synthesis of proteins that are ... has made major contributions to our comprehension of the molecular mechanisms controlling MHCII genes and has made this system ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...
WikiGenes - Grin1 - glutamate receptor, ionotropic, NMDA1...
Glutamate is a major excitatory neurotransmitter in the mammalian central nervous system, and the N-methyl-D-aspartate- ... Furthermore, mice lacking PSD-93 exhibit blunted NMDAR-dependent persistent pain induced by peripheral nerve injury or ... The rat pheochromocytoma cell line (PC12) has been used as a model system for NR1 gene expression studies [4]. ... By using the yeast two-hybrid system, we found that calmodulin interacts with the COOH terminus of the NR1 subunit and ...
WikiGenes - CSPG4 - chondroitin sulfate proteoglycan 4
In the adult central nervous system, two distinct populations of glial cells expressing the chondroitin sulfate proteoglycan ... peripheral myelin protein-22 and NG2 chondroitin sulfate proteoglycan, which are expressed originally in developmental glial ... protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system ...