This makes PC12 cells useful as a model system for neuronal differentiation and neurosecretion. Treatment of PC12 cells with ... Wikipedia articles containing the term "PC12 cells" [1] Ras function was partially elucidated using PC12 cell line [2], from ... been studied using this cell line to understand their effects on PC12 cells These types of studies show that use of PC12 cell ... "The PC12 cell as model for neurosecretion: PC12 cells as model for neurosecretion". Acta Physiologica. 192 (2): 273-285. doi: ...

Learn about PC12 Cells at online-medical-dictionary.org ... PC12 Cells. Synonyms. Cell Line, Pheochromocytoma. Cell Lines, ... A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal ... differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation. ... PC12 Cell. Pheochromocytoma Cell Line. Pheochromocytoma Cell Lines. ...

... confirming that PC12 cells differentiated into mature neuronal cells by ASK1. Moreover, ASK1DeltaN-expressing PC12 cells ... Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells J Biol Chem. 2000 Mar ... We found that p38 and to a lesser extent JNK, but not ERK, were activated by the expression of ASK1DeltaN in PC12 cells. ... ASK1 thus appears to mediate signals leading to both differentiation and survival of PC12 cells. Together with previous reports ...

... selectively stabilizes the GAP-43 mRNA in PC12 cells. To study the cellular mechanisms for this post-tra ... N I Perrone-Bizzozero, V V Cansino, D T Kohn; Posttranscriptional regulation of GAP-43 gene expression in PC12 cells through ... In conclusion, these data suggest that PKC activity regulates the levels of the GAP-43 mRNA in PC12 cells through a novel, ... We have previously shown that nerve growth factor (NGF) selectively stabilizes the GAP-43 mRNA in PC12 cells. To study the ...

The purpose of this research was to investigate ameliorations of Se counter to iHg-mediated toxicity in PC12 cells. Cytotoxic ... Selenium modulates inorganic mercury induced cytotoxicity and intrinsic apoptosis in PC12 cells. This item is licensed under: ... Selenium modulates inorganic mercury induced cytotoxicity and intrinsic apoptosis in PC12 cells. ... and up-regulating cleaved caspase 3 and cytochrome c release in PC12 cells 48 h after incubation. Co-treatment of Se (5 mu M) ...

PC12 cells were plated on 60-mm collagen-coated dishes (6 × 106cells/dish) and incubated for 6-12 h in a low-serum medium (0.25 ... Cell Culture PC12 cells were maintained in RPMI 1640 medium (Roswell Park Memorial Institute, developed by Dr. G. Moore) ... For c-Fos detection, PC12 cells (1 × 107cells/dish) were plated on collagen-coated dishes, stimulated with 50 mM KCl at 37°C ... PC12 cells were stimulated with 50 μM KCl for the indicated periods of time or with KCl for 2 min at 37°C after pretreatment ...

... PISIGNANO, DARIO 2015-01-01. Abstract. In ... Differentiated PC12 cells were characterized by highly aligned and longer neurites on parallel PHB fibres with respect to ... Differentiated PC12 cells were characterized by highly aligned and longer neurites on parallel PHB fibres with respect to ... PC12 pheochromocytoma cells that mimic central dopaminergic neurons and represent a model for neuronal differentiation were ...

PC12) cells after Aβ1-42 exposure. In addition, D3T pretreatment inhibited Aβ1-42 induced cell apoptosis as well as protein ... PC12) cells after Aβ1-42 exposure. In addition, D3T pretreatment inhibited Aβ1-42 induced cell apoptosis as well as protein ... PC12) cells after Aβ1-42 exposure. In addition, D3T pretreatment inhibited Aβ1-42 induced cell apoptosis as well as protein ... PC12) cells after Aβ1-42 exposure. In addition, D3T pretreatment inhibited Aβ1-42 induced cell apoptosis as well as protein ...

Therefore, we examined whether any increase of intracellular iron in serum-starved PC12 cells could block the cell death even ... in PC12 cells, and an iron-NO complex such as dinitro-iron complex (DNIC) is found to keep the cells from apoptosis by ... Previously we observed that serum-starved PC12 cells maintained their viability only for a couple of days even in the presence ... Cytoprotective Role of Intracelluar Iron on Serum-starved PC12 Cells under NGF. So-Young Choi and Jun-Mo Chung* ...

The PC-12 HD-Q23 cell lines 14 and 7 can be used for in-vitro assay development for neurodegenerative diseases. The ... PC-12 HD-Q23: Cell Lines 14 and 7 Invented by David Rubensztein Invented at University of Cambridge ... The PC-12 HD-Q23 cell lines 14 and 7 can be used for in-vitro assay development for neurodegenerative diseases. The huntingtin ... PC-12 HD-Q74: Cell Lines 10 and 1b Invented by David Rubensztein at University of Cambridge ...

PKA-Mediated Regulation of B/K Gene Transcription in PC12 Cells 의 이용 수, 등재여부, 발행기관, 저자, 초록, 목차, 참고문헌 등 논문에 관한 다양한 정보 및 관련논문 목록과 ... PKA-Mediated Regulation of B/K Gene Transcription in PC12 Cells PKA-Mediated Regulation of B/K Gene Transcription in PC12 Cells ... We examined the specific signaling pathway that regulates the transcription of B/K in PC12 cells. When the cells were treated ... Effect of forskolin, dibutyryl cAMP and CGS21680 was significantly reduced in PKA-deficient PC12 cell line (PC12-123.7). One ...

Lokhov P.G. et al., Study of specific binding and uptake of ligand(peptide)-coated liposomes by cells PC12 cells. Voprosy ... Study of specific binding and uptake of ligand(peptide)-coated liposomes by cells PC12 cells // Voprosy Meditsinskoi Khimii. - ... Study of specific binding and uptake of ligand(peptide)-coated liposomes by cells PC12 cells. ... coated liposomes by cells PC12 cells. Voprosy Meditsinskoi Khimii, 45(2), 136-139. ...

Gemfibrozil protect PC12 cells through modulation of Estradiol receptors against oxidative stress ... Ashabi G, Khalaj L. Gemfibrozil protect PC12 cells through modulation of Estradiol receptors against oxidative stress. Physiol ... Materials and Methods: In this study, neuronal-like PC12 cells with were pretreated with different concentrations of ... Types of Manuscript: Experimental research article , Subject: Cell, Stem Cell and Cancer ...

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Martinus, R. D., & Cook, C. J. (2011). The effect of complement C5a on mitochondrial functions of PC12 cells. NeuroReport, 22( ... The effect of complement C5a on mitochondrial functions of PC12 cells. / Martinus, R.D.; Cook, C.J. In: NeuroReport, Vol. 22, ... Martinus, R.D. ; Cook, C.J. / The effect of complement C5a on mitochondrial functions of PC12 cells. In: NeuroReport. 2011 ; ... Martinus, RD & Cook, CJ 2011, The effect of complement C5a on mitochondrial functions of PC12 cells, NeuroReport, vol. 22, no ...

As confirmation that ligand density in these engineered systems impacts neuronal cell behavior, we demonstrate that increasing ... As confirmation that ligand density in these engineered systems impacts neuronal cell behavior, we demonstrate that increasing ... neural cell adhesion molecule). Physical adsorption isotherms were experimentally determined for these engineered proteins, ... and reproducible surfaces for in vitro studies of cell-ligand interactions and for potential application as coatings on neural ...

buchneri MS partially or completely protected neuronal cells against neurotoxicant-induced cell death. ... by Lactobacillus buchneri isolated from kimchi and its neuroprotective effect on neuronal cells J Microbiol Biotechnol. 2007 ...

We used undifferentiated PC-12 cells to study the effect of epinephrine and carbachol on transmembranous currents. Applying the ... Four pertussis toxin-sensitive G proteins were identified in membranes of PC-12 cells: two members of the Gi family, Gi1 and ... Inhibition of Ca2+ channels via alpha 2-adrenergic and muscarinic receptors in pheochromocytoma (PC-12) cells ... Inhibition of Ca2+ channels via alpha 2-adrenergic and muscarinic receptors in pheochromocytoma (PC-12) cells. ...

Versatile roles of R-Ras GAP in neurite formation of PC12 cells and embryonic vascular development. In: Journal of Biological ... Versatile roles of R-Ras GAP in neurite formation of PC12 cells and embryonic vascular development. Journal of Biological ... We found that R-Ras GAP is down-regulated during neurite formation in rat pheochromocytoma PC12 cells by nerve growth factor ( ... Dive into the research topics of Versatile roles of R-Ras GAP in neurite formation of PC12 cells and embryonic vascular ...

Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine ... is critical for NGF-induced neuronal differentiation of PC12 cells. We have found that NGF promoted the interaction of Gβγ with ... it was observed that overexpression of Gβγ in PC12 cells induced neurite outgrowth in the absence of added NGF. Moreover, ... overexpressed Gβγ exhibited a pattern of association with MTs similar to that observed in NGF-differentiated cells. Altogether ...

Physical mobilization of secretory vesicles facilitates neuropeptide release by nerve growth factor-differentiated PC12 cells. ... Here, high resolution green fluorescent protein (GFP)-based measurements in nerve growth factor-differentiated PC12 cells are ... Here, high resolution green fluorescent protein (GFP)-based measurements in nerve growth factor-differentiated PC12 cells are ... Here, high resolution green fluorescent protein (GFP)-based measurements in nerve growth factor-differentiated PC12 cells are ...

These results demonstrated that the sea cucumber ovum peptide-derived NDEELNK might play a protective role in PC12 cells. ... Our results demonstrated that NDEELNK supplementation alleviated scopolamine-induced PC12 cell damage by improving the ... Neuroprotective effects of NDEELNK from sea cucumber ovum against scopolamine-induced PC12 cell damage through enhancing energy ... activity in PC12 cells. By molecular docking, we confirmed that the NDEELNK backbone and AChE interacted through hydrophobic ...

PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla. PC12 cells stop dividing and terminally ... GenJet DNA In Vitro Transfection Reagent for PC12 cell is pre-optimized for most efficiently transfecting PC12 cells. ... GenJet In Vitro DNA Transfection Reagent for PC-12 Cell [SL100489-PC12] - Description ... PC12 cells. PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla. PC12 cells stop dividing and ...

... induced cytotoxicity in PC12 cells was examined. Cultured PC12 cells were either treated with MPP+ alone or co-treated with one ... Both linoleic acid and arachidonic acid are able to inhibit MPP+-induced toxicity in PC12 cells. The protection is not mediated ... Cells treated with 500 μM MPP+ for a day reduced cell viability to ~70% as compared to control group. Linoleic acid (50 and 100 ... Cell viability was then assessed by using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. ...

Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation ... B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP. ( ... B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP.. ... The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal ...

Changes of energy metabolism induced by 1-methyl-4-phenylpyridinium (MPP+)-Related compounds in rat pheochromocytoma PC12 cells ... Changes of energy metabolism induced by 1-methyl-4-phenylpyridinium (MPP+)-Related compounds in rat pheochromocytoma PC12 cells ... Changes of energy metabolism induced by 1-methyl-4-phenylpyridinium (MPP+)-Related compounds in rat pheochromocytoma PC12 cells ... Changes of energy metabolism induced by 1-methyl-4-phenylpyridinium (MPP+)-Related compounds in rat pheochromocytoma PC12 cells ...

Comparison of neurons derived from mouse P19, rat PC12 and human SH-SY5Y cells in the assessment of chemical- and toxin-induced ... Comparison of neurons derived from mouse P19, rat PC12 and human SH-SY5Y cells in the assessment of chemical- and toxin-induced ... RT @ECACC: in vitro evaluation of chemical-induced neurotoxicity in #Cells @ECACC cells in research! - https://t.co/ZsLLlBcHQk ... in vitro evaluation of chemical-induced neurotoxicity in #Cells @ECACC cells in research! - https://t.co/ZsLLlBcHQk https://t. ...

Dive into the research topics of Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via ... Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of ... Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of ... Indirubin-3-Oxime Effectively Prevents 6OHDA-Induced Neurotoxicity in PC12 Cells via Activating MEF2D Through the Inhibition of ...

Rat pheochromocytoma PC12 cells were incubated with hydroxytyrosol (10 µM, 180 min) alone or with the MAO-A inhibitor ... Rat pheochromocytoma PC12 cells were incubated with hydroxytyrosol (10 µM, 180 min) alone or with the MAO-A inhibitor ... Rat pheochromocytoma PC12 cells were incubated with hydroxytyrosol (10 µM, 180 min) alone or with the MAO-A inhibitor ... Rat pheochromocytoma PC12 cells were incubated with hydroxytyrosol (10 µM, 180 min) alone or with the MAO-A inhibitor ...