Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in...
The DUX4 transcription factor has DNA binding domains similar to several paired class homeotic transcription factors, but only ... Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in ... Overexpression of PAX3 or PAX7 in mouse myoblasts (but not overexpression of other paired class homeotic transcription factors ... and PAX7 protein by immunostaining cells in differentiating cultures with antibodies recognizing each transcription factor. All ...https://skeletalmusclejournal.biomedcentral.com/articles/10.1186/s13395-017-0130-1
benign granular cell myoblastoma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
PAX7 Transcription Factor; 0 / Pax7 protein, mouse; 0 / Transforming Growth Factor beta ... PAX7 Transcription Factor / genetics. Transforming Growth Factor beta / genetics. *[MeSH-minor] Animals. Cell Line, Tumor. Mice ... Transcription Factors; 47E5O17Y3R / Phenylalanine; 63231-63-0 / RNA; 73Y7P0K73Y / Thioctic Acid; 9G2MP84A8W / Deoxyglucose; EC ... Immunologic Factor. A220.127.116.11.3.6. Receptor. A18.104.22.168.4. Indicator, Reagent, or Diagnostic Aid. A22.214.171.124.5. Hazardous or ...http://www.bmlsearch.com/?kwr=benign+granular+cell+myoblastoma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
Muscle Stem Cell Self Renewal is Regulated by Acetylation of PAX7 by Marie-Claude Sincennes, Caroline E. Brun, Tabitha...
PAX7 protein is regulated by different post-tr ... The transcription factor PAX7 is a critical regulator of ... The transcription factor PAX7 is a critical regulator of satellite cell survival, self-renewal and proliferation. PAX7 protein ... both of which control PAX7 acetylation levels and PAX7 target gene expression in myoblasts. MYST1 and SIRT2 are also important ... Abolishing PAX7 acetylation using CRISPR/Cas9 mutant mice impairs muscle regeneration and leads to progressive satellite cell ...https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3416644
Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy *René G. Feichtinger ... Rights & permissionsfor article Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy . Opens ...https://www.nature.com/search?author=%22Uwe%20Ahting%22&error=cookies_not_supported&code=fabc34ea-3813-4944-a3ff-242cba83bf85
Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy *René G. Feichtinger ... Rights & permissionsfor article Biallelic variants in the transcription factor PAX7 are a new genetic cause of myopathy . Opens ...http://www.nature.com/search?author=%22Johannes%20A.%20Mayr%22&error=cookies_not_supported&code=c2ad2cdd-16b7-407f-b136-4690186c3479
ZFIN Publication: Mahalwar et al., 2014
PAX7 Transcription Factor/genetics; PAX7 Transcription Factor/metabolism; SOXE Transcription Factors/genetics; SOXE ... Transcription Factors/metabolism; Skin Pigmentation/genetics; Skin Pigmentation/physiology*; Time-Lapse Imaging; Zebrafish/ ...http://zfin.org/ZDB-PUB-140913-1
Effects of Human Mesenchymal Stem Cells Isolated from Wharton's Jelly of the Umbilical Cord and Conditioned Media on Skeletal...
They are characterized by the expression of transcription factor Pax7 which is a paired box protein . Through IHC, we tried ... The Pax7 labelling index was defined as the percentage of Pax7 positive nuclei, which was determined by counting at least 1000 ... The Pax7+ labeling index was defined by the average number of Pax7+ positive nuclei which was determined by counting 5 selected ... MSCs secrete a variety of cytokines and growth factors like hepatocyte growth factor (HGF), IL-10, or adrenomedullin that may, ...https://www.hindawi.com/journals/sci/2014/376918/
Study uncovers a previously unknown subtype of muscle stem cells
Researchers previously assumed that a certain protein - the transcription factor PAX7 - plays a key role in muscle regeneration ... He himself was initially guided by the assumption that the transcription factor was crucial for muscle growth. I previously ... The team instead discovered something else in those cells in which the transcription factor was missing: CLEC14A, a protein ... Spuler presumes that PAX7 is not equally important for every cell. This would explain why Lavin can walk and climb relatively ...https://www.news-medical.net/news/20191221/Study-uncovers-a-previously-unknown-subtype-of-muscle-stem-cells.aspx
Pattern of Pax7 expression during myogenesis in the posthatch chicken establishes a model for satellite cell differentiation...
The paired-box transcription factor Pax7 plays a critical role in the specification of satellite cells in mouse skeletal muscle ... In muscle tissues, Pax7 protein expression was the strongest by 1 day posthatch, declining on days 3 and 6 to a similar level. ... Pattern of Pax7 expression during myogenesis in the posthatch chicken establishes a model for satellite cell differentiation ... In the present study, the position and number of Pax7-expressing cells found in muscles of growing and adult chickens confirm ...https://www.ncbi.nlm.nih.gov/pubmed/15390217?dopt=Abstract
Recent Publications in Neural Development | Center for Integrative Brain Research
Regulation of the development of tectal neurons and their axonal projections by transcription factors Brn3a and Pax7. ... Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J. Neuroscience ... Neural Development - The roles of Brn3a, Islet1, and Hmx1 transcription factors in nervous system development ...http://depts.washington.edu/cibr/?page_id=749
Fedtsova N[au] - PubMed - NCBI
Regulation of the development of tectal neurons and their projections by transcription factors Brn3a and Pax7. ... Direct autoregulation and gene dosage compensation by POU-domain transcription factor Brn3a. ... POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ... POU-domain factor expression in the trigeminal ganglion and implications for herpes virus regulation. ...https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Fedtsova+N%5Bau%5D&dispmax=50
OPUS Würzburg | Search
In particular, I focused on the role of Pax7 transcription factor, a paired domain protein. The results suggested that Pax7 was ... Over expression of Pax7 in dorsal midbrain led to an enlarged tectum accompanied by a raise in cell division, while Pax7 ... Pax7 also positively regulated Pax3, another pair-ruled gene expressed dorsally. These results suggest that Pax7 very likely ... Overexpression of Rab23 indicated that it facilitated the expression of Pax7 and Pax3 in the neural tube and suppressed ventral ...https://opus.bibliothek.uni-wuerzburg.de/solrsearch/index/search/searchtype/authorsearch/author/Naixin+Li/start/0/rows/10/yearfq/2009
Frontiers | The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development | Frontiers in Aging...
Unlike trunk muscle stem cells, head muscle stem cells do not have a previous history of Pax7 expression, instead Pax7 ... Unlike trunk muscle stem cells, head muscle stem cells do not have a previous history of Pax7 expression, instead Pax7 ... using Pax7 as key marker. Our study reveals a common theme of head muscle stem cell development that is quite different from ... using Pax7 as key marker. Our study reveals a common theme of head muscle stem cell development that is quite different from ...https://www.frontiersin.org/articles/10.3389/fnagi.2015.00062/full
2018 Till & McCulloch Meetings - Agenda | Online Registration by Cvent
"Recessive mutations in the transcription factor PAX7 are a new genetic cause of human myopathy leading to the exhaustion of the ... "Pioneer transcription factors shape the epigenetic landscape". 3:45 PM - 4:00 PM Farshad Babaeijandaghi, University of British ...http://www.cvent.com/events/2018-till-mcculloch-meetings/agenda-8ee4f7ed0a874f81a6739a6f3742503e.aspx
Gαi2 Signaling Is Required for Skeletal Muscle Growth, Regeneration, and Satellite Cell Proliferation and Differentiation |...
The transcription factor Pax7 is a marker of SCs and is required for their development and maintenance in adult life (8). To ... Myogenic factors that regulate expression of muscle-specific microRNAs. Proc. Natl. Acad. Sci. U. S. A. 103:8721-8726. doi: ... 2D). These results were also confirmed at the gene expression level by real-time PCR for Pax7, which demonstrated no difference ... 4C). In contrast, Pax7 expression was not affected by ablation of Gαi2 (Fig. 4C). During muscle repair, newly formed and ...https://mcb.asm.org/content/34/4/619.long
Publication of the Month 2007
The Pax3 and Pax7 transcription factors play essential roles in the early specification, migration, and myogenic ... The Pax3 and Pax7 transcription factors play essential roles in the early specification, migration, and myogenic ... In addition to anatomic location, satellite cells are typified by markers such as M-cadherin, Pax7, Myf5, and neural cell ... In addition to anatomic location, satellite cells are typified by markers such as M-cadherin, Pax7, Myf5, and neural cell ...http://www.mirm.pitt.edu/category/publication-of-the-month/publication-of-the-month-2007/
Functional Overload Enhances Satellite Cell Properties in Skeletal Muscle
All satellite cells express the stem-cell-specific transcription factor, paired-box 7 (Pax7). In addition, activated satellite ... The proportion of Pax7(+) cells per myofibers (c) or the proportion of Pax7(+)MyoD(+) cells per total Pax7(+) cells (d) is ... Activated satellite cells express the myogenic regulatory factors (MRFs) Myf5 and MyoD, two key transcription factors for ... in addition to the stem-cell-specific transcription factor Pax7 . We investigated changes in the number as well as the ...https://www.hindawi.com/journals/sci/2016/7619418/
Molecular cytogenetic analysis consistently identifies translocations involving chromosomes 1, 2 and 15 in five embryonal...
Paired Box Transcription Factors. PAX7 Transcription Factor. Forkhead Transcription Factors. Research team. Sarcoma Molecular ... The risk factors that drive this disparity are unknown and potentially consist of social, environmental, and genetic influences ...https://repository.icr.ac.uk/handle/internal/1930
Satellite cells are well known to express the transcription factor Pax7 in both their quiescent and actively proliferating ... of Pax7+ cells (303 of 706 Pax7+ cells), and Id3 staining was present in ∼29% of Pax7+ cells (208 of 727 Pax7+ cells) at day 3 ... these quiescent mononuclear cells express the paired box transcription factor Pax7 and, in some muscle types, Pax3. On muscle ... Id family of transcription factors and vascular lesion formation. Arterioscler Thromb Vasc Biol 24: 2014-2020, 2004. ...http://ajpcell.physiology.org/content/298/5/C1087
PAX7 - Wikipedia
Pax7 is a transcription factor that plays a role in myogenesis through regulation of muscle precursor cells proliferation. It ... Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene. Pax-7 plays a role in neural crest ... PAX7 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) PAX7 human gene location in the UCSC ... However, PAX7 is not required for spermatogenesis, as mice without PAX7+ spermatogonia show no deficits in fertility. PAX7 may ...https://en.wikipedia.org/wiki/PAX7
Neuroblast-specific open chromatin allows the temporal transcription factor, Hunchback, to bind neuroblast-specific loci | eLife
... thereby biasing the subsequent binding of transcription factors to produce neuroblast-specific neurons. ... the closely related mammalian Pax3 and Pax7 transcription factors can recruit histone methyltransferase to promote open ... spatial transcription factors or STFs, paralleling the naming of temporal transcription factors as TTFs. The Gooseberry (Gsb) ... and all of them are transcription factors or signalling pathways with transcription factor effectors. Henceforth we refer to ...https://elifesciences.org/articles/44036
PAX7 Gene - GeneCards | PAX7 Protein | PAX7 Antibody
Complete information for PAX7 gene (Protein Coding), Paired Box 7, including: function, proteins, disorders, pathways, ... Targeted motifs for PAX7 Gene. HOMER Transcription Factor Regulatory Elements motif PAX7 * Consensus sequence: TAATCAATTA ... Enhancers around PAX7 on UCSC Golden Path with GeneCards custom track Transcription factor binding sites by QIAGEN in the PAX7 ... for PAX7 Gene Localization for PAX7 Gene Subcellular locations from UniProtKB/Swiss-Prot for PAX7 Gene. Nucleus.. *P23759-PAX7_ ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=PAX7
Testosterone-Regulated Genes May Affect Vaccine-Induced Immunity | Technology Networks
Pax7, a transcription factor, is able to open up compacted genome segments to allow cell growth to occur properly. ...https://www.technologynetworks.com/biopharma/news/testosteroneregulated-genes-may-affect-vaccineinduced-immunity-211371
A Way to Sequence DNA of Rare Animals Has Been Discovered
Pax7, a transcription factor, is able to open up compacted genome segments to allow cell growth to occur properly. ...https://www.technologynetworks.com/applied-sciences/news/a-way-to-sequence-dna-of-rare-animals-has-been-discovered-280971
Mouse monoclonal to TLR2 | Akt Inhibitor A-443654 Interferes with Mitotic Progression
paired box transcription factor Pax7 (Seale et al., 2000) and are thought to originate from mesodermal cells expressing Pax7 ... of Pax7-expressing SCs, which have never expressed Myf5, show a privileged contribution to the SC compartment compared to Pax7- ... Concomitant with the loss of Pax7-positive SCs, we also noted a rapid decline of Pax7 mRNA concentrations in TAM-treated Pax7CE ... Skeletal muscle contains Pax7-expressing muscle stem or satellite cells, enabling muscle. Posted on February 13, 2018. by ...http://a-443654.com/tag/mouse-monoclonal-to-tlr2/