Pathological Conditions, Signs and SymptomsCells, CulturedSignal TransductionPathological Conditions, AnatomicalModels, BiologicalGene Expression RegulationNeuronsMice, Inbred C57BLRats, Sprague-DawleyBrainMice, KnockoutNeoplasmsAstrocytesImmunohistochemistryNeovascularization, PhysiologicRNA, MessengerRats, WistarOxidative StressDisease Models, AnimalEndothelial CellsEndothelium, VascularReactive Oxygen SpeciesMice, TransgenicInflammationNeurodegenerative DiseasesPurinergic P2X Receptor AntagonistsCell LineCalciumHomeostasisApoptosisNitric OxideCalcium SignalingTime FactorsBlotting, WesternCell DifferentiationCell MovementMyocardiumMolecular Sequence DataBlood VesselsCell ProliferationNeovascularization, PathologicBrain DiseasesMitochondriaCell DeathDose-Response Relationship, DrugVascular Endothelial Growth Factor AReverse Transcriptase Polymerase Chain ReactionOxidation-ReductionPatch-Clamp TechniquesMyocytes, CardiacEnzyme ActivationFibroblastsAcid Sensing Ion ChannelsCentral Nervous SystemProtein BindingEnzyme InhibitorsCapillary PermeabilityCell CommunicationPhosphorylationDental PulpMembrane ProteinsCardiovascular SystemAgingMicrogliaLiverGene ExpressionBiological MarkersAutophagyAmino Acid SequenceAntioxidantsNeurogliaKidneyUp-RegulationHippocampusPregnancyExtracellular MatrixNerve Tissue ProteinsCell SurvivalExtracellular SpaceModels, CardiovascularCalpainAnimals, NewbornGap JunctionsProteinsHydrogen-Ion ConcentrationHEK293 CellsGene Expression ProfilingDown-RegulationCollagenKineticsAnoxiaGene Expression Regulation, EnzymologicMacrophagesMicroRNAsReactive Nitrogen SpeciesPericytesFlow CytometryReference ValuesProtein IsoformsBase Sequence