Risk of dominant mutation in older fathers: evidence from osteogenesis imperfecta. - Semantic Scholar
... the risk of mutant OI increases with paternal age. However, the rate of increase of risk with paternal age appears to be ... which disappeared after adjusting for paternal age. No significant increase in maternal or paternal age was found in cases ... There was also an increase in mean maternal age (not significant) ... was significantly higher than that of population controls and remained so after adjusting for maternal age. ...https://www.semanticscholar.org/paper/Risk-of-dominant-mutation-in-older-fathers%3A-from-Carothers-McAllion/d7e5bf9dc2bd49faa234abd9ab912196d42a8c73
Possible technical and biological explanations for the 'parental telomere length inheritance discrepancy' enigma - Semantic...
Paternal and maternal TL inheritance has been typically reported as correlation of 'current' parental TL and offspring TL. This ... The impact will depend on the TL itself and therefore the age of the population. As well the nonlinearity in qPCR measurements ... We propose that stronger maternal or paternal inheritance in a specific cohort will be the net effect of these and additional ... However, the two studies that report ruling out non-paternity1,9 are also the only studies not supporting stronger paternal- ...https://www.semanticscholar.org/paper/Possible-technical-and-biological-explanations-for-Meyer-Eisenberg/cc6f574445c750498c367c253bcf41410d195259
Association of childhood leukemia with maternal age, birth order, and paternal occupation. A case-control study. - Semantic...
No difference was found between case and control groups for maternal age or paternal occupation. Analyses with stratification ... Socioeconomic status and paternal benzene exposure were determined from the paternal occupation stated on the birth certificate ... and paternal occupation. In this study, 255 childhood leukemia cases diagnosed in California between 1975 and 1980 were ... on age, sex, and leukemia cell type are reported. ... the association between childhood leukemia and maternal age, ...https://www.semanticscholar.org/paper/Association-of-childhood-leukemia-with-maternal-ag-Shaw-Lavey/11c2b9785c974fca11b0ecb16ab02f9be8fb5749
Three-probe fluorescence in situ hybridization to assess chromosome X, Y, and 8 aneuploidy in sperm of 14 men from two healthy...
... aneuploidy in sperm of aged mice provides inter-species corroborating evidence for this preliminary finding of a paternal age ... X and Y and applied to semen of 14 men from two healthy groups who differed in their average ages (46.8 +/- 3.1 years, n = 4 v ... evidence for a paternal age effect on sperm aneuploidy.. *. Will Robbins, Julie Baulch, D. Moore, Heinz-ulrich G. Weier, David ... The effects of male aging on semen quality, sperm DNA fragmentation and chromosomal abnormalities in an infertile population. * ...https://www.semanticscholar.org/paper/Three-probe-fluorescence-in-situ-hybridization-to-8-Robbins-Baulch/23eac5d499c3d7b0fd5c5ff6dc96af5d6c35a91a
Advanced paternal age and risk of fetal death: a cohort study. - Semantic Scholar
... age effect on offspring health due to mutations of paternal origin should be reflected in an association between paternal age ... The paternal age-related risk of late fetal death was higher than the risk of early fetal death and started to increase from ... The paternal age-related risks of fetal death and its components, early and late fetal loss, were estimated using survival ... Pregnancies fathered by a man aged 50 or more years (n = 124) had almost twice the risk of ending in a fetal loss compared with ...https://www.semanticscholar.org/paper/Advanced-paternal-age-and-risk-of-fetal-death%3A-a-Andersen-Hansen/ac00e82349f4adb40b7885298404797737ecc7c5
Advancing paternal age and the risk of schizophrenia. - Semantic Scholar
Categories of mother's age showed no significant effects, after adjusting for paternal age. CONCLUSIONS These findings support ... METHOD We investigated whether the risk of schizophrenia was associated with advancing paternal age in a population-based birth ... we found that paternal age was a strong and significant predictor of the schizophrenia diagnoses, but not of other psychiatric ... After controlling for maternal age and other confounding factors (sex, ethnicity, education [to reflect socioeconomic status], ...https://www.semanticscholar.org/paper/Advancing-paternal-age-and-the-risk-of-Malaspina-Harlap/491a5802d3879810796659f7653c5e6ba6830088
Birth Outcome of Children Fathered by Men Treated with Systemic Corticosteroids during the Conception Period - A Cohort Study...
This study is the largest to date examining the effect of paternal use of SCS prior to conception on birth outcome. We found no ... The outcome was congenital abnormalities (CAs), pre-term birth and small-for-gestational age (SGA). We adjusted for co-variates ... we examined the association between paternal use of SCS prior to conception and adverse birth outcome. The study includes data ... and there is little available evidence regarding possible adverse effects of paternal use of systemic corticosteroids (SCS). In ...https://www.semanticscholar.org/paper/Birth-Outcome-of-Children-Fathered-by-Men-Treated-Larsen-Friedman/1d68faecfc98e9fe77a2e9b761b75dddf2dfc395
The effects of sex condition, genotype and diet on bovine muscle fiber characteristics. - Semantic Scholar
... breed type and dietary energy level on muscle fiber characteristics were examined at various ages and related to carcass ... Maternal and Paternal Genomes Differentially Affect Myofibre Characteristics and Muscle Weights of Bovine Fetuses at ... The effects of sex condition, breed type and dietary energy level on muscle fiber characteristics were examined at various ages ... Between Meat Quality Characteristics and Nutritional Composition of Nandanam Quail-III Slaughtered at Different Ages. *Raju ...https://www.semanticscholar.org/paper/The-effects-of-sex-condition%2C-genotype-and-diet-on-Seideman-Crouse/b6dbfb751e1d0be778081cac5838673d81a6ca12
Area-level poverty and preterm birth risk: A population-based multilevel analysis - Semantic Scholar
... with a similar effect at earlier gestational ages (, 32 weeks), adj OR 1.27 (95% CI 1.06, 1.52). CONCLUSION Women residing in ... Paternal race is a risk factor for preterm birth.. *Lisanne M Palomar, Emily A. DeFranco, Kirstin A Lee, Jenifer E. Allsworth, ... Gestational Age. Search for additional papers on this topic. Explore Further: Topics Discussed in This Paper. ...https://www.semanticscholar.org/paper/Area-level-poverty-and-preterm-birth-risk%3A-A-DeFranco-Lian/ace4c2cdcf4f95d22e2d565e995df8ae870f9d7e
Quantifying the threat of extinction from Muller's ratchet in the diploid Amazon molly (Poecilia formosa) - Semantic Scholar
... including paternal leakage of undamaged DNA from sexual sister species, compensatory mutations and many others. More research ... In most cases, extinction is expected to occur within a time frame that is less than previous estimates of the age of the ... Aging asexual lineages and the evolutionary maintenance of sex.. *Eddie Ka Ho Ho, Aneil F. Agrawal ...https://www.semanticscholar.org/paper/Quantifying-the-threat-of-extinction-from-Muller%27s-Loewe-Lamatsch/47f3a82716fd93a0d0e1c2a25d703b94376d71b3
Discrimination of complete hydatidiform mole from its mimics by immunohistochemistry of the paternally imprinted gene product...
p57KIP2 immunohistochemistry can reliably identify most cases of complete hydatidiform mole irrespective of gestational age and ... Human GRB10 is imprinted and expressed from the paternal and maternal allele in a highly tissue- and isoform-specific fashion. ...https://www.semanticscholar.org/paper/Discrimination-of-complete-hydatidiform-mole-from-Castrillon-Sun/1a7e5789fdfcd92890b1a40b190e3113b3df7b9c
Parental origin and germline mosaicism of deletions and duplications of the dystrophin gene: a European study - Semantic Scholar
In five BMD families the ratio between paternal and maternal origin of new mutations was 3∶2. Recurrence risk because of ... the ratio between the paternal and the maternal origin of this new mutation was 32:49 (binomial test P = 0.075) for DMD. ... Germline origins in the human F9 gene: frequent G:C→A:T mosaicism and increased mutations with advanced maternal age. *R. P. ... Germinal mosaicism from grand-paternal origin in a family with Duchenne muscular dystrophy. *Mireille Claustres, Paule ...https://www.semanticscholar.org/paper/Parental-origin-and-germline-mosaicism-of-deletion-Essen-Abbs/cd0c437d9a535c29747bdfa1831f98a4c0c4453d
Associations between a Mediterranean diet pattern and inflammatory biomarkers in European adolescents. - Semantic Scholar
... paternal and maternal education, adiposity, and smoking habits. RESULTS The Mediterranean diet score was positively associated ... Multivariate and multiple linear regression analyses were adjusted for age, sex, country, socioeconomic status, ... and metabolic parameters with C-reactive protein and neutrophil-to-lymphocyte ratio in middle-aged and older adults with ...https://www.semanticscholar.org/paper/Associations-between-a-Mediterranean-diet-pattern-Arouca-Michels/8c98a5675f456ac799b132c4096fecc2eb9e9484
Pregnancy outcome and uterine fibroids. - Semantic Scholar
Patients' age, myoma size, myoma location, and interval between myomectomy and pregnancy may influence the pregnancy rate and ... Maternal and Paternal Infertility Disorders and Treatments and Autism Spectrum Disorder: Findings from the Study to Explore ...https://www.semanticscholar.org/paper/Pregnancy-outcome-and-uterine-fibroids.-Parazzini-Tozzi/62b0b07cf81e187dca71180dff5096108698d441
Ambient air pollution triggers wheezing symptoms in infants. - Semantic Scholar
... age, exposure to smoking and paternal history of asthma. RESULTS Significant positive associations were found between ... albeit attenuating after the age of 1 year. CONCLUSIONS Air pollution related to traffic is significantly associated with ... concentrations of PM(10), NO(2), NO(x), CO and wheezing symptoms in infants (aged 0-1 year) with a delay of 3-4 days. Only the ... A study was undertaken to examine the effect of exposure to air pollution on wheezing symptoms in children under the age of 3 ...https://www.semanticscholar.org/paper/Ambient-air-pollution-triggers-wheezing-symptoms-in-Andersen-Loft/5b39d4609eefdf84f503394ab5c915169b985c1b