What does p300-cbp transcription factors mean?
Meaning of p300-cbp transcription factors. What does p300-cbp transcription factors mean? Information and translations of p300- ... cbp transcription factors in the most comprehensive dictionary definitions resource on the web. ... Definition of p300-cbp transcription factors in the Definitions.net dictionary. ... What does p300-cbp transcription factors mean?. Definitions for p300-cbp transcription factors. p300-cbp tran·scrip·tion fac· ...https://www.definitions.net/definition/p300-cbp%20transcription%20factors
Characterization of CEE-target gene interaction dista | Open-i
... and found that they have a significant propensity to be bound by p300, an enhancer binding transcription factor.In total, our ... and found that they have a significant propensity to be bound by p300, an enhancer binding transcription factor.In total, our ... and found that they have a significant propensity to be bound by p300, an enhancer binding transcription factor. Furthermore, ... and found that they have a significant propensity to be bound by p300, an enhancer binding transcription factor. Furthermore, ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3643598_gkt188f6p&req=4
FHL2 | Cancer Genetics Web
p300-CBP Transcription Factors. *Chromosome 2. *Breast Cancer. *Transcription Factors. *Cell Proliferation ... transcription coactivator activity - transcription factor binding - transcription, DNA-dependent - ventricular cardiac muscle ... FHL1 binds to the p300/CBP co-activators and disrupts binding with HIF-1α. FHL3 does not bind to HIF-1α or p300, indicating ... Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that promotes angiogenesis, metabolic reprogramming, and other ...http://www.cancerindex.org/geneweb/FHL2.htm
"Critical and Independent Roles of the P/CAF Acetyltransferase in ARF-p" by Ian M. Love
One manner in which to address this question is at the level of transcription initiation-after upstream signals converge on p53 ... Dissertations, UMMS; Tumor Suppressor Protein p53; p300-CBP Transcription Factors. Abstract. For 30 years, the tumor suppressor ... One manner in which to address this question is at the level of transcription initiation-after upstream signals converge on p53 ...http://escholarship.umassmed.edu/gsbs_diss/663/
DI-fusion Nerve growth factor receptor signaling induces histone...
Transcription, Genetic. Tumor Suppressor Protein p53 -- metabolism. p300-CBP Transcription Factors. Note générale:. Journal ... Nerve growth factor receptor signaling induces histone acetyltransferase domain-dependent nuclear translocation of p300/CREB- ... Nerve growth factor receptor signaling induces histone acetyltransferase domain-dependent nuclear translocation of p300/CREB- ... binding protein-associated factor and hGCN5 acetyltransferases.. par Wong, Kasuen;Zhang, Junyu;Awasthi, Soumya;Sharma, Anima; ...http://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/51735/Details
Potential enhancer elements are enriched for p300 bindi | Open-i
a) P300 binding site enrichment in CEEs. (b) Pol ... Potential enhancer elements are enriched for p300 binding, and ... and found that they have a significant propensity to be bound by p300, an enhancer binding transcription factor.In total, our ... and found that they have a significant propensity to be bound by p300, an enhancer binding transcription factor.In total, our ... and found that they have a significant propensity to be bound by p300, an enhancer binding transcription factor. Furthermore, ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3643598_gkt188f5p&req=4
Challenge Awards-Class of 2017 - PCF
Project Title: Targeting CBP/p300 to Suppress Oncogenic Transcription Factors in Advanced Prostate Cancer Description: *The ... This project will examine the molecular impact of CBP/p300 on DNA repair activity in prostate cancer models. Whether CBP/p300- ... the role and mechanisms of CBP/p300 in prostate cancer and be used to optimize the design of clinical trials testing CBP/p300- ... consequences of CBP/p300 inhibition in prostate cancer using preclinical models and tissues from patients treated with CBP/p300 ...https://www.pcf.org/c/challenge-awards-class-2017/
Cited2 is an essential regulator of adult hematopoietic stem cells. - Nuffield Department of Orthopaedics, Rheumatology and...
By using loss-of-function approaches, we report a selective and cell-autonomous requirement for the p300/CBP-binding ... p300-CBP Transcription Factors, Adult Stem Cells, Transcriptional Activation ... By using loss-of-function approaches, we report a selective and cell-autonomous requirement for the p300/CBP-binding ... Oxford scientists discover key factor that 'alerts' stem cells to accelerate healing of multiple tissues ...https://www.ndorms.ox.ac.uk/publications/105941
Cited2 is an essential regulator of adult hematopoietic stem cells. - The Kennedy Institute of Rheumatology
By using loss-of-function approaches, we report a selective and cell-autonomous requirement for the p300/CBP-binding ... p300-CBP Transcription Factors ... ADP-Ribosylation Factors, Adult Stem Cells, Animals, Cell ... By using loss-of-function approaches, we report a selective and cell-autonomous requirement for the p300/CBP-binding ...https://www.kennedy.ox.ac.uk/publications/105941
Mammalian PIAS3 interacts with the coactivator p300/CBP and the transcription factor Smad3 (Long et al., 2004b). Recruitment of ... MYC transcription factor ICE1, and MYB transcription factor MYB15 function in a regulatory cascade to modulate expression of ... for nuclear factor of activated T cells), p53 tumor suppressor, Smad4, and Tcf-4 is necessary for transcription factor activity ... The MYC-like transcription factor ICE1, which is necessary for low temperature induction of CBF/DREB1 (Chinnusamy et al., 2003 ...http://www.plantcell.org/content/19/4/1403
Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor...
p300-CBP Transcription Factors/metabolism*. Substances. *Isoenzymes. *Molecular Chaperones. *p300-CBP Transcription Factors ...https://www.ncbi.nlm.nih.gov/pubmed/21700219?access_num=21700219&link_type=MED&dopt=Abstract
A Human RNA Polymerase II Complex Containing Factors That Modify Chromatin Structure | Molecular and Cellular Biology
1997) The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol. 7:232-236. ... Transcription assays.Transcription reaction mixtures were reconstituted as described previously (11). Transcription factors ... 1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature (London) 382:319-324. ... The large RNAPII complex was also found to contain two or three histone acetyltransferases, p300 and/or CBP and PCAF. CBP and ...https://mcb.asm.org/content/18/9/5355?ijkey=8537ba27781a6c2aab9d2341b4974914a7bc03ec&keytype2=tf_ipsecsha
Frontiers in Bioscience: A virtual library of medicine
Transcriptional activation of cartilage oligomeric matrix protein by Sox9, Sox5, and Sox6 transcription factors and CBP/p300 ... Energy balance pathways converging on the Nhlh2 transcription factor. Dana L. Fox, Kristen R. Vella, Deborah J. Good. [ ... BS69, a corepressor interacting with ZHX1, is a bifunctional transcription factor. Hiroko Ogata-Kawata, Kazuya Yamada, Miki ... Identification of genes differentially regulated by transcription factor, AP-2delta. Liyun Sun, Shengdong Huang, Qihan Wu, ...https://www.bioscience.org/landmark/12l/2007
Gene profiling of normal human bronchial epithelial cells in response to asbestos and benzo(a)pyrene diol epoxide (BPDE).
Transcription factors, including activating transcription factor 3 and Cbp/p300-interacting transactivator, were upregulated by ... Profiles of genes regulated by chrysotile were dominated by cytokines, growth factors, and DNA damage. Profiles of genes with ...http://www.biomedsearch.com/nih/Gene-profiling-normal-human-bronchial/18197826.html
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. - PubMed - NCBI
p300-CBP Transcription Factors/antagonists & inhibitors*. *p300-CBP Transcription Factors/chemistry. *p300-CBP Transcription ... p300/CBP siRNAs inhibit cell proliferation and p300/CBP activity in LnCaP-FGC cells ... Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.. Lasko LM1, Jakob CG1, Edalji RP1 ... Here, we describe A-485, a potent, selective and drug-like catalytic inhibitor of p300 and CBP. We present a high resolution ( ...https://www.ncbi.nlm.nih.gov/pubmed/28953875
IRF7 - Википедия
Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP ... Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA ... RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity. • DNA binding. ... positive regulation of transcription, DNA-templated. • positive regulation of transcription from RNA polymerase II promoter. • ...https://ru.wikipedia.org/wiki/IRF7
SH2 Domain-Containing Protein Tyrosine Phosphatases | Harvard Catalyst Profiles | Harvard Catalyst
p300-CBP Transcription Factors. *Protein Tyrosine Phosphatase, Non-Receptor Type 11. *Enzyme Assays ...https://connects.catalyst.harvard.edu/Profiles/display/Concept/SH2%20Domain-Containing%20Protein%20Tyrosine%20Phosphatases
Experts and Doctors on tumor cell line in Houston, United States
kruppel like transcription factors*neuropilin 2*e2f1 transcription factor*tyrphostins*taurodeoxycholic acid*p300 cbp ... sp4 transcription factor*cyclin e*arachidonate 15 lipoxygenase*mantle cell lymphoma*epha2 receptor*i kappa b kinase*sp3 ... sp transcription factors*nuclear receptor coactivator 2*fenretinide*proto oncogene proteins c mdm2*70 kda ribosomal protein s6 ... Our study uncovers the mechanism by which extrinsic RA-signal and intrinsic transcription factor Ngn2 cooperate for cell fate ...http://www.labome.org/locale/united/texas/experts-and-doctors-on-tumor-cell-line-in-houston--united-states-63781.html
ZZ zinc finger - Wikipedia
ZZ-type zinc finger domains are found in: Transcription factors P300 and CBP. Plant proteins involved in light responses, such ... The site of interaction with the tumour suppressor protein p53 and the oncoprotein E1A with CBP/P300 is a Cys-rich region that ... utrophin and an 87kDa post-synaptic protein contain a ZZ-type zinc finger with high sequence identity to P300/CBP ZZ-type zinc ... CBP) and ADA2. CBP provides several binding sites for transcriptional coactivators. ...https://en.wikipedia.org/wiki/ZZ_zinc_finger
Heat shock protein 47 - Wikipedia
"Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2". The Journal of Biological ... "Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription". Molecular Cell. 6 (5): 1059- ... by TGF-beta and IL-1 beta via enhancement of the heat shock element binding activity of heat shock transcription factor 1". ... Razzaque MS, Ahmed AR (March 2002). "Collagens, collagen-binding heat shock protein 47 and transforming growth factor-beta 1 ...https://en.wikipedia.org/wiki/Heat_shock_protein_47
Anti-CITED2 antibody - N-terminal (ab189946) | Abcam
Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP. ... Cbp/p300 interacting transactivator 2 antibody. *Cbp/p300 interacting transactivator with Glu/Asp rich carboxy terminal domain ...https://www.abcam.com/cited2-antibody-n-terminal-ab189946.html
nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate | Development
1997) CBP/p300 as a co-factor for the Microphthalmia transcription factor. Oncogene 14, 3083-3092. ... 1994) microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. Genes Dev 8 ... 1997) Functional analysis of microphthalmia-associated transcription factor in pigment cell-specific transcription of the human ... 1998) The rat microphthalmia-associated transcription factor gene (Mitf) maps at 4q34-q31 and is mutated in the mib rats. Mamm ...http://dev.biologists.org/content/126/17/3757?ijkey=e89ca6078fec43c915ca0e9622803eb223d0e795&keytype2=tf_ipsecsha
KAKEN - Research Projects | Regulation of cellular function by viral RNA sensors (KAKENHI-PLANNED-20112009)
Journal Article] Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 ... Presentation] Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without ... Journal Article] Impairment of interferon regulatoroy factor-3 activation by hepatitis C virus core protein basic amino acid ... the role of intracellular antiviral factors.2012. *. Author(s). Xing F, Matsumiya T, Onomoto K, Hayakari R, Imaizumi T, Yoshida ...https://kaken.nii.ac.jp/grant/KAKENHI-PLANNED-20112009/
CREB-Binding Protein Acetylates Hematopoietic Transcription Factor GATA-1 at Functionally Important Sites | Molecular and...
1997) The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol. 7:230-236. ... Such multifunctional interactions may account for the observed synergy between transcription factors that use CBP and p300 as ... 1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382:319-324. ... This demonstrates that CBP can strongly stimulate the acetylation of a transcription factor in vivo and that this activity is ...https://mcb.asm.org/content/19/5/3496?ijkey=9517af90c6376297f6f96a7c5af034e60ae85cf1&keytype2=tf_ipsecsha
Full Publication List | Wagner Lab
Structural Basis for Recruitment of p300/CBP by Transcription Factor HIF-1, Proc. Natl. Acad. Sci. USA. 99, 5367-5372 (2002). ... C. H. Lin, B. Hare, G. Wagner, S. C. Harrison, T. Maniatis, E. Fraenkel: A small domain of CBP/p300 binds diverse proteins: ... Y. Yamamoto, C. R. Singh, A. Marintchev, N. S. Hall, E. M. Hannig, G. Wagner, and K. Asano: The eukaryotic initiation factor ( ... C.M Fletcher, T.V. Pestova, C.U.T. Hellen, G. Wagner: Structure and interactions of the translation initiation factor eIF1, ...http://gwagner.med.harvard.edu/publications