AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation Science
InkCyclin-Dependent Kinase Inhibitor p16Cyclin-Dependent Kinase Inhibitor p15Tumor Suppressor Protein p14ARFCyclin-Dependent Kinase Inhibitor p18Cyclin-Dependent Kinase Inhibitor p19Genes, p16Cell AgingCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Cyclin-Dependent KinasesTumor Suppressor ProteinsRetinoblastoma ProteinChromosomes, Human, Pair 9Cell Cycle ProteinsDNA MethylationGenes, Tumor SuppressorCarrier ProteinsGene DeletionPolycomb Repressive Complex 1Cell CycleCyclin-Dependent Kinase Inhibitor p21PrintingTumor Suppressor Protein p53Ink Blot TestsCyclinsTattooingProto-Oncogene ProteinsPolymorphism, Single-Stranded ConformationalCyclin-Dependent Kinase Inhibitor p27G1 PhaseDNA, NeoplasmGenes, p53Cyclin D1Promoter Regions, GeneticGene SilencingPolymerase Chain ReactionCell Transformation, NeoplasticImmunohistochemistryGene Expression Regulation, NeoplasticFibroblastsCervical Intraepithelial NeoplasiaGenes, RetinoblastomaCpG IslandsTumor Cells, CulturedGenes, rasCell DivisionCyclin DLoss of HeterozygosityUterine Cervical NeoplasmsCarcinoma, Squamous CellCell ProliferationRepressor ProteinsMutationPolycomb-Group ProteinsMelanomaCells, CulturedGene Expression RegulationSepiaNuclear ProteinsRNA, MessengerKi-67 AntigenCell Line, TumorCyclin-Dependent Kinase 2Reverse Transcriptase Polymerase Chain ReactionHomozygoteBase SequenceMice, KnockoutExonsTumor Markers, BiologicalPapillomaviridaeEnzyme InhibitorsCyclin-Dependent Kinase Inhibitor ProteinsPongamiaMolecular Sequence DataTelomeraseMice, TransgenicCell Line, TransformedPapillomavirus InfectionsDNA-Binding ProteinsCDC2-CDC28 KinasesSkin NeoplasmsDown-RegulationMice, Inbred C57BLE2F1 Transcription FactorNeoplasm ProteinsDNA PrimersProtein-Serine-Threonine KinasesNeoplasms, Squamous CellCell LineElectrowettingras Proteins
Institute for Healthy Aging - Publications - HSC
Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: ...
https://experts.unthsc.edu/en/organisations/institute-for-healthy-aging/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Farticle
Referenser - RCC KunskapsbankenReferenser - RCC Kunskapsbanken
HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53, but lack p16ink4a ... P16INK4a expression in patients with penile cancer. PLoS One. 2018;13(10):e0205350.. ... Prevalence of human papillomavirus DNA and p16(INK4a) in penile cancer and penile intraepithelial neoplasia: a systematic ...
https://kunskapsbanken.cancercentrum.se/diagnoser/peniscancer/vardprogram/referenser/
Michael D McClean, ScDMichael D McClean, ScD
Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma. Int J Cancer. 2006 Oct 1; ... Duration but not intensity of alcohol and tobacco exposure predicts p16INK4A homozygous deletion in head and neck squamous cell ...
https://profiles.bu.edu/Michael.McClean
Peiqing Sun, PhD | Wake Forest University School of MedicinePeiqing Sun, PhD | Wake Forest University School of Medicine
miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways.. Su W, Hong L, Xu X, Huang S ...
https://school.wakehealth.edu/faculty/s/peiqing-sun
Witte | UCLA Broad Stem Cell CenterWitte | UCLA Broad Stem Cell Center
Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf. Published in Genes & ...
https://stemcell.ucla.edu/node/1026
UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM - Terms starting with 'E' - MEDINDEX.AM
ETS1 also regulates p16(INK4A) gene expression. The human gene is located at 11q23.3. ( NCI )] (UMLS (NCI) C0812380) ETS; ... RB/E2F repression mediates G1 arrest triggered by TGFB, by p16(INK4A), and by contact inhibition. Accumulation of G1 cyclins E ...
http://www.medindex.am/glossary/index.php/list/UMLS.+CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM/,E.xhtml
PDF) PREPARATION OF HISTOLOGICAL SPECIMENS - PDFSLIDE.USPDF) PREPARATION OF HISTOLOGICAL SPECIMENS - PDFSLIDE.US
p16 (INK4a) has clinicopathological and prognostic impact ......oropharynx and 35 larynx specimens from primary HNSCC patients ...
https://pdfslide.us/documents/preparation-of-histological-specimens.html
PathPlus™ GPR78 Polyclonal Antibody Rabbit anti-Human IHC | LSBio
IHC‑plus™ p16INK4a / CDKN2A Antibody LS‑B1347 Species: Human, Mouse, Rat Applications: IHC, IHC - Paraffin, Immunofluorescence ...
https://lsbio-7d62.kxcdn.com/pathplus-antibodies/pathplus-gpr78-antibody-c-terminus-ihc-ls-a3278/475
Angeliki Malliri - Research output - Research Explorer The University of Manchester
Association of CDKN2A/p16INK4A with human head and neck keratinocyte replicative senescence: relationship of dysfunction to ...
https://research.manchester.ac.uk/en/persons/angeliki.malliri/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Farticle
A new, effective and high-yield approach for identifying liver tumor suppressors | Genome Medicine | Full TextA new, effective and high-yield approach for identifying liver tumor suppressors | Genome Medicine | Full Text
... which encodes p16INK4A and p14ARF, E cadherin, AXIN1 and AXIN2 [14, 15]. ...
https://genomemedicine.biomedcentral.com/articles/10.1186/gm26
The Cellient System for Cytohistology to Analyze p16 Positive Dyskeratocytes in Paraffin Sections of HPV-Positive Cervical...The Cellient System for Cytohistology to Analyze p16 Positive Dyskeratocytes in Paraffin Sections of HPV-Positive Cervical...
Usefulness of liquid-based cytology specimens for the immunocytochemical study of p16INK4a expression and human papillomavirus ... p16INK4a expression in cervical premalignant and malignant lesions. Exp Mol Pathol 2006; 80: 192-96. http://dx.doi.org/10.1016/ ... p16INK4a overexpression and HPV infection in uterine cervix adenocarcinoma. Virchows Arch 2006; 448: 597-603. http://dx.doi.org ...
https://www.neoplasiaresearch.com/pms/index.php/jao/article/view/107
IMMUNOHISTOCHEMICAL INVESTIGATIONS OF P16 INK 4A EXPRESSION IN CARCINOMAS AND HIGH GRADE CERVICAL LESIONSIMMUNOHISTOCHEMICAL INVESTIGATIONS OF P16 INK 4A EXPRESSION IN CARCINOMAS AND HIGH GRADE CERVICAL LESIONS
Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J ... Role of P16(INK4a) expression in identifying CIN2 or more severe lesions among HPV-positive patients referred for colposcopy ... Key words: cervical carcinomas, human papilloma viruses, p16 INK4a expression, - Download FULL TEXT (PDF - 1814 KB). Please ... 7. Negri G1, Egarter-Vigl E, Kasal A, Romano F, Haitel A, Mian C. p16INK4a is a useful marker for the diagnosis of ...
http://www.journal-imab-bg.org/statii-07/vol13book1p24-26.html
Open Journal SystemsOpen Journal Systems
P16INK4A Expression in Bowens Disease and Bowenoid Papulosis. Auepemkiate S, Thongsuksai P, Boonyaphiphat P ...
http://www.jmatonline.com/index.php/jmat/article/index?type=OA&order=&articlesPage=17
2011 | 香川大学医学部自律機能生理
Pioglitazone promotes preadipocyte proliferation by downregulating p16(Ink4a).. Biochem Biophys Res Commun 411(2): 375-380, ...
http://www.med.kagawa-u.ac.jp/~cardiovasc-physiol/custom47.html
Multiple Myeloma Lab Results Explained - HealthTree for Multiple MyelomaMultiple Myeloma Lab Results Explained - HealthTree for Multiple Myeloma
Rb pathway inactivation (P16/INK4a, P18/INK4c, RB1). *PTEN inactivation. *P53 inactivation (17p13) ...
https://healthtree.org/myeloma/community/resources
Maloney, Kelly | Colorado PROFILES
Lack of ETV6 (TEL) gene rearrangements or p16INK4A/p15INK4B homozygous gene deletions in infant acute lymphoblastic leukemia. ... Different patterns of homozygous p16INK4A and p15INK4B deletions in childhood acute lymphoblastic leukemias containing distinct ...
https://profiles.ucdenver.edu/display/225338/Network/ResearchAreas/212407
New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis | Arthritis Research & Therapy | Full...New insights on the MMP-13 regulatory network in the pathogenesis of early osteoarthritis | Arthritis Research & Therapy | Full...
p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in ...
https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-017-1454-2
9 Ways to Reduce Inflammation | BioHeal Ottawa9 Ways to Reduce Inflammation | BioHeal Ottawa
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature. 2016 Feb 11;530(7589):184-9. doi: 10.1038/ ...
https://biohealottawa.com/2020/11/08/9-ways-to-reduce-inflammation/
Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence | BMC Molecular and...
For example, both p14ARF and p16INK4A isoforms of the CDKN2A gene, which increases with cellular senescence [28], were down- ... Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature. 2016;530:184-9. ...
https://0-bmcmolcellbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12860-017-0147-7
CIENCIASMEDICASNEWS: Happy New Year: Looking Back at 2016 Research Highlights
4] Naturally occurring p16Ink4a-positive cells shorten healthy lifespan. Baker DJ, Childs BG, Durik M, Wijers ME, Sieben CJ, ...
https://elbiruniblogspotcom.blogspot.com/2017/01/happy-new-year-looking-back-at-2016.html
Immunosenescence in neurocritical care | Journal of Intensive Care | Full TextImmunosenescence in neurocritical care | Journal of Intensive Care | Full Text
By specifically eliminating cells with p16INK4A, which is a biomarker of aging, the development of age-related diseases can be ... Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature. 2011;479:232-6. ... Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature. 2016;530:184-9. ...
https://jintensivecare.biomedcentral.com/articles/10.1186/s40560-018-0333-5
Epigenetic dysregulation in cardiovascular aging and diseaseEpigenetic dysregulation in cardiovascular aging and disease
p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages. Blood 2011;118: ... Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature 2016;530:184-9. ...
https://www.oaepublish.com/articles/jca.2021.16
Senolytics and Senostatics: A Two-Pronged Approach to Target Cellular Senescence for Delaying Aging and Age-Related DiseasesSenolytics and Senostatics: A Two-Pronged Approach to Target Cellular Senescence for Delaying Aging and Age-Related Diseases
Knockout of p16INK4A, one of the key regulator of senescence, partially rescued these stem cell exhaustion and functional ... Knockout of p16INK4A, one of the key regulator of senescence, partially rescued these stem cell exhaustion and functional ... Upon the administration of a synthetic drug called rapalog, p16INK4A positive senescent cells are removed in this system by ... Upon the administration of a synthetic drug called rapalog, p16INK4A positive senescent cells are removed in this system by ...
https://www.molcells.org/journal/view.html?pn=minireview&uid=4064&vmd=Full
Epigenetic dysregulation in cardiovascular aging and diseaseEpigenetic dysregulation in cardiovascular aging and disease
p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages. Blood 2011;118: ... Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature 2016;530:184-9. ...
https://oaepublish.com/articles/jca.2021.16
Human Genome Epidemiology Literature Finder|Home|PHGKB
Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma. ...
https://phgkb.cdc.gov/PHGKB/searchSummary.action?firstQuery=Oropharyngeal%20Neoplasms+and+EGFR&Mysubmit=Search
Kenneth Alum - U.S. Transhumanist Party - Official Website
2] Mosteiro, L., Pantoja, C., Martino, A., & Serrano, M. (2017). Senescence promotes in vivo reprogramming through p16INK4a and ...
https://transhumanist-party.org/author/kenneth-alum/
What Are Senolytics? Senotherapeutics for Senescent CellsWhat Are Senolytics? Senotherapeutics for Senescent Cells
In preclinical studies, naturally aged mice treated with 318H saw a 66% reduction of p16INK4a-positive senescent cells and an ... Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature, 479(7372), 232-236. ...
https://www.lifespan.io/topic/senolytics/
Naviga IRISNaviga IRIS
p16(INK4a) and pl9(ARF) germline mutations in familial melanoma 1-gen-1997 Fargnoli, MARIA CONCETTA; Chimenti, S; Keller, G; ... p16 (INK4a, MTS-1) gene polymorphism and methylation status in human pituitary tumors 1-gen-1999 Jaffrain, MARIE LISE; Ferretti ... p16(INK4a) and pl9(ARF) germline mutations in familial melanoma. 1997-01-01 Fargnoli, MARIA CONCETTA; Chimenti, S; Keller, G; ... p16 (INK4a, MTS-1) gene polymorphism and methylation status in human pituitary tumors. ...
https://ricerca.univaq.it/browse?type=contributorAppartenenza&sort_by=ASC&order=1&rpp=20&etal=-1&value=Dipartimento+di+Scienze+cliniche+applicate+e+biotecnologiche&starts_with=P&filter_value_display=
Production, Characterization and Potential Uses of a 3D Tissue-engineered Human Esophageal Mucosal Model. - PDF Download FreeProduction, Characterization and Potential Uses of a 3D Tissue-engineered Human Esophageal Mucosal Model. - PDF Download Free
Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation. Mol. Cancer Res. 1, (10), ...
https://d.docksci.com/production-characterization-and-potential-uses-of-a-3d-tissue-engineered-human-e_5a41f77ad64ab2bd31829576.html
Hiroshi Nishio - Research output - Keio University
P16INK4a immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia: ...
https://keio.elsevierpure.com/en/persons/hiroshi-nishio/publications/