Oxonic Acid | Profiles RNS
"Oxonic Acid" by people in UAMS Profiles by year, and whether "Oxonic Acid" was a major or minor topic of these publications. ... "Oxonic Acid" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "Oxonic Acid" by people in Profiles over the past ten years. ... Below are MeSH descriptors whose meaning is more general than "Oxonic Acid". ...
A comprehensive treatment for peritoneal metastases from gastric cancer with curative intent | Lund University Publications
Febuxostat Attenuates Renal Damage besides Exerting Hypouricemic Effect in Streptozotocin-Induced Diabetic Rats
Daily urinary albumin (UAE), uric acid (UUA), and creatinine (UCr) excretion were also significantly increased in these rats. ... Diabetic rats showed significantly increased serum uric acid (SUA), serum creatinine (SCr), and urea nitrogen (BUN) levels. ... A. Eräranta, V. Kurra, A. M. Tahvanainen et al., "Oxonic acid-induced hyperuricemia elevates plasma aldosterone in experimental ... and oxonic acid-induced hyperuricemic rat models [37]. Moreover, in STZ-induced diabetic rat models, Lee et al. [28] showed ...
List of MeSH codes (D03) - Wikipedia
... oxonic acid MeSH D03.383.931.674 - prometryne MeSH D03.383.931.819 - simazine MeSH D03.383.931.915 - triethylenemelamine MeSH ... pipemidic acid MeSH D03.383.725.547.650 - piromidic acid MeSH D03.383.725.547.900 - 3-pyridinecarboxylic acid, 1,4-dihydro-2,6- ... niflumic acid MeSH D03.066.515.635 - pipemidic acid MeSH D03.066.515.650 - piromidic acid MeSH D03.066.515.950 - xanthinol ... nalidixic acid MeSH D03.438.810.835.055.550 - nedocromil MeSH D03.438.810.835.055.580 - oxolinic acid MeSH D03.438.810.835.188 ...
PDF) The effect of oxygenated water in Diabetes Mellitus
... or after oxonic acid treatment. Serum uric acid was measured to confirm the effects on uric acid metabolism. Following ... Hyperuricemia in rats was induced by treatment with oxonic acid potassium salt, and the animals were given oxygenated drinking ... A significant improvement in uric acid metabolism and rate of increase in serum uric acid concentration was observed in ... The purpose of this study was to assess the effects of short-term and long-term drinking of oxygenated water on lactic acid and ...
XORTX Presents New Proof Of Concept Data At American Society Of Nephrology | MENAFN.COM
strong> ● Xanthine Oxidase Inhibition with XRx-008 Blocks Uric Acid Induced Increase in Total Kidney Weight ... In summary, increasing serum uric acid by inhibiting uricase with oxonic acid ("OXO") results in an increase in kidney weight, ... In rodents, uricase converts uric acid to allantoin and uricase inhibition raises serum uric acid. The aim of this study was to ... confirming that increasing uric acid by inhibiting uricase enzyme metabolism of uric acid to allantoin, results in ...
Hypoxia and Tubulointerstitial Injury: A Final Common Pathway to End-Stage Renal Failure - ScienceOpen
Recent studies have reported that mild hyperuricemia in normal rats induced by the uricase inhibitor, oxonic acid (OA), results ... Given observations that uric acid induces vascular disease, the effect of uric acid on vascular smooth muscle cells in culture ... A role for uric acid in the progression of renal disease.. Duk-Hee Kang, Takahiko Nakagawa, Lili Feng … (2002) ... Benziodarone reduced uric acid levels less effectively and only partially improved BP and renal function, with minimal effect ...
Hyperuricemia exacerbates chronic cyclosporine nephropathy<...
... and oxonic acid alone (OA). Histological and functional studies were determined at sacrifice. Results. CSA treated rats ... An increase in uric acid exacerbates CSA nephropathy in the rat. The mechanism does not involve intrarenal uric acid crystal ... An increase in uric acid exacerbates CSA nephropathy in the rat. The mechanism does not involve intrarenal uric acid crystal ... An increase in uric acid exacerbates CSA nephropathy in the rat. The mechanism does not involve intrarenal uric acid crystal ...
EdgarFiling
The aim of the study was to determine whether raising serum uric acid with the uricase inhibitor oxonic acid (OXO) was ... Humans are predisposed to chronically high uric acid and gout because they lack uricase that converts uric acid to allantoin. ... In rodents uricase converts uric acid to allantoin and uricase inhibition raises serum uric acid. ... Most importantly, results of this study show that increased serum uric acid can accelerate injury in two separate models of PKD ...
Nefropatía por ácido úrico: caracterización de mecanismos independientes del depósito de cristales en la génesis y progresión...
Alopurinol/farmacologia
Methods: HUA was induced in male ICR mice by dietary supplements of uric acid and oxonic acid potassium salt, with or without ... Discovery of coumaric acid derivatives hinted by coastal marine source to seek for uric acid lowering agents. ... Ellagic acid (EA), which is widely distributed in many foods, has been found to possess inhibitory activity against xanthine ... The amino acid residues Thr1077, Gln762, Phe914, Ala1078, Val1011, Glu1194, and Ala1079 were located closer to the binding site ...
1: J Ethnopharmacol
... oxonic acid (500 mg/kg p.o., 1 h before the test drugs), and measured plasma uric acid values in rats. Oral propolis had a ... The extract contains amino acids, phenolic acids, phenolic acid esters, flavonoids, cinnamic acid, terpenes and caffeic acid. ... Oleic acid-induced lung injury in rats and effects of caffeic acid phenethyl ester.. Koksel O, Kaplan MB, Ozdulger A, Tamer L, ... The new esters belonged to 4-methoxyhydrocinnamic acid, hydroferulic acid and ferulic acid. El-Saff propolis had a very high ...