Pituitary-specific positive transcription factor 1 - Wikipedia
Szeto DP, Ryan AK, OConnell SM, Rosenfeld MG (July 1996). "P-OTX: a PIT-1-interacting homeodomain factor expressed during ... POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1), also known as POU1F1, is a transcription factor ... "Entrez Gene: POU1F1 POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1)". Dasen JS, OConnell SM, Flynn ... PIT1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Transcription+Factor+Pit-1 at the ...
CDD Conserved Protein Domain Family: LIM bind
... to enhance transcriptional efficiency by acting as co-factors for LIM homeodomain and Otx class transcription factors both of ... Chip is a ubiquitous chromosomal factor required for normal expression of diverse genes at many stages of development. It is ... suggested that Chip cooperates with different LIM domain proteins and other factors to structurally support remote enhancer- ...
ZFIN Gene: otx2b
Transcription factor Otx. Transcription factor Otx2. Transcription factor Otx, C-terminal. UniProtKB:Q1RM25 InterPro ... Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory ... Transcription factor Otx2. Family. IPR003025 Transcription factor Otx. Homologous_superfamily. IPR009057 Homeobox-like domain ... Transcription factor Otx, C-terminal. Family. IPR003022 ...
otx2 Summary
otx-2 , otx2-a , otx2-b , otxA , Xotx-2 , Xotx2 [+] , [-] ( Nomenclature history ) Gene Function:. homeodomain transcription ... factor Protein Function :. May play a central role in the initial events of axis formation and in particular in specifying ... Otx TF C, Otx TF, Otx2 TF, Homeobox CS, Homeobox-like sf [-] ...
Cephalopod DNA/Molecular/Genetic Studies/Health
Studying the expression of conserved transcription factors (Pax and NK families, otx, apt) and morphogen (hedgehog) during ... Homeodomain (HD) genes are transcription factors that regulate transcription of downstream genes through DNA binding, and as ... and the C2H2 superfamily of zinc-finger transcription factors. Extensive messenger RNA editing generates transcript and protein ...
Choroid Plexus Papilloma: Practice Essentials, Problem, Epidemiology
Among the abnormalities identified was up-regulation of the TWIST-1 transcription factor, which was shown to promote ... Recurrent gains of foci harboring the genes OTX, LAMB1, and TRPM3 were found in all cases in this series. [26] ... Platelet-derived growth factor receptor expression and activation in choroid plexus tumors. Am J Pathol. 2009 Oct. 175(4):1631- ... Platelet-derived growth factor receptor expression and amplification in choroid plexus carcinomas. Mod Pathol. 2008 Mar. 21(3): ...
Wei Liu - Grants - Albert Einstein College of Medicine
OTX2 Monoclonal Antibody (OTI1A1) (TA809511)
... regulation of fibroblast growth factor receptor signaling pathway positive regulation of transcription, DNA-templated positive ... Protein Aliases: Homeobox protein OTX2; Orthodenticle homolog 2; OTX Gene Aliases: CPHD6; MCOPS5; OTX2 ... transcription from RNA polymerase II promoter protein complex assembly axon guidance regulation of smoothened signaling pathway ... OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription ...
Otx1 and Otx2 activities are required for the normal development of the mouse inner ear | Development | The Company of...
Both Otx genes are bicoid- like transcription factors. So far, there is no evidence that either of these genes directly ... Functions of Otx genes in the inner ear. Lateral crista and canal. When Otx genes were activated in the developing otocyst, the ... Therefore, although the lack of proper coiling of the cochlea was one of the manifestations in Otx mutant mice, the role of Otx ... TRP-2/DT, a new melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor ...
Transcription factor classification
Ben-Gurion University of the Negev - Research output - Ben-Gurion University Research Portal
Intramyocardial Injections of Nanoparticles Loaded With Hepatic Growth Factor and Insulin-Like Growth Factor-1 Improve ... Immunogenetics of factor VIII inhibitor development. Lozier, J., Menashe, I., Kroner, B., Goedert, J. & Rosenberg, P., 23 Mar ... Is elective cesarean delivery at term a risk factor for long term respiratory morbidity of the offspring?. Baumfeld, Y., ... Intrauterine Exposure to Opioids in the First Trimester as a Risk Factor for Malformations in Newborns and Abortuses. Fishman, ...
PITX1 Antibody | Affinity Biosciences
Kei Yura - 研究成果 - 早稲田大学
Distinct evolutionary rate in the eye field transcription factors found by estimation of ancestral protein structure. Kamijyo, ... CFI 25 Subunit of Cleavage Factor i is Important for Maintaining the Diversity of 3 UTR Lengths in Arabidopsis thaliana (L.) ...
Antonio Simeone
Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non- ... The Otx family. Curr Opin Genet Dev 12, 409-415 (2002). 106) B. Cipelletti, G. Avanzini, L. Vitellaro-Zuccarello, S. ... a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family. Mechanisms of ... The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic ...
Yasuoka Y et al. (2014), Occupancy of tissue-specific cis-regulatory mod... - Paper
However, the molecular mechanisms by which Otx and other transcription factors (TFs) interact with the genome to direct head ... Dynamic in vivo binding of transcription factors to cis-regulatory modules of cer and gsc in the stepwise formation of the ... Weeder Web: discovery of transcription factor binding sites in a set of sequences from co-regulated genes. 2004, Pubmed Puelles ... Master transcription factors and mediator establish super-enhancers at key cell identity genes. 2013, Pubmed Wilson, ...
The mammalian Crx genes are highly divergent representatives of the Otx5 gene family, a gnathostome orthology class of...
Otx Transcription Factors, Photoreceptor Cells, Phylogeny, Sequence Homology, Amino Acid, Trans-Activators, Zebrafish Proteins ...
New genes in the evolution of the neural crest differentiation program | Genome Biology | Full Text
... which are present in homeobox-containing transcription factors that belong to the Otx, Cdx, and Hox9 families, respectively ( ... Thus, key transcription factors acting as both neural plate border specifiers (such as Pax3, Dlx5, Zic, and Msx1/2) and ... and Bmp families cooperate to activate a distinct combination of transcription factors at the neural plate border. Among those ... Butte MJ: Neurotrophic factor structures reveal clues to evolution, binding, specificity, and receptor activation. Cell Mol ...
Omega Therapeutics to Host Conference Call to Discuss Preliminary Clinical Data for OTX-2002 from Ongoing MYCHELANGELO™ I Trial...
MYC is a master transcription factor that regulates cell proliferation, differentiation and apoptosis and plays a significant ... About OTX-2002. OTX-2002 is an mRNA therapeutic delivered via lipid nanoparticles (LNPs) designed to downregulate MYC ... These and other important factors discussed under the caption "Risk Factors" in our Quarterly Report on Form 10-Q for the ... Additionally, OTX-2002 has shown robust anti-tumor activity alone and in combination with standard of care therapies in vivo in ...
Comparative analysis of gnathostome Otx gene expression patterns in the developing eye: implications for the functional...
This analysis indicates that each Otx class is characterized by highly specific and conserved expression features in the ... These data indicate that specific functions selectively involving each Otx orthology class were fixed prior to the gnathostome ... We have performed a detailed analysis of the expression pattern of the three gnathostome Otx classes in order to gain new ... Otx Transcription Factors, Retina, Transcriptional Activation ... This analysis indicates that each Otx class is characterized by ...
Efrinas/genética
The long non-coding RNA TAZ-AS202 promotes lung cancer progression via regulation of the E2F1 transcription factor and ... and ERK-mediated control of Otx gene expression, which involves both an activator and a repressor of ETS-family transcription ... but increases the protein level of the transcription factor E2F1, which in turn regulates the expression of a large set of ... Factor de Transcripción E2F1/genética , Factor de Transcripción E2F1/metabolismo , Efrinas/genética , Efrinas/metabolismo , ...
Leber Congenital Amaurosis - American Academy of Ophthalmology
CRX is a transcription factor essential for both photoreceptor outer segment elongation and phototransduction cascade as it ... Kimura A, Singh D, Wawrousek EF, Kikuchi M, Nakamura M, Shinohara T. Both PCE-1/RX and OTX/CRX interactions are necessary for ... Disease pathway 3 includes the retinal transcription factor, which includes CRX. Disease pathway 4 involves intra-flagellar ... Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: ...
DeCS
Onecut Transcription Factors [D12.776.260.400.624] Onecut Transcription Factors * Otx Transcription Factors [D12.776.260.400. ... Thyroid Nuclear Factor 1 - Preferred Concept UI. M0181663. Scope note. A homeobox protein and transcription factor that ... factor nuclear tiroideo 1. Entry term(s). factor de transcripción tiroideo 1 factor nuclear tiroideo TTF-1 proteína 1 homeobox ... 2018; THYROID NUCLEAR FACTOR 1 was indexed under NUCLEAR PROTEINS and TRANSCRIPTION FACTORS 1990-2017. ...
MH DELETED MN ADDED MN
Otx Transcription Factors D12.776.930.621 D12.776.930.650 Ouabain D4.808.155.160.861.600 Outpatient Clinics, Hospital N2.278. ... Transcription Factor Brn-3 D12.776.930.632.625 D12.776.930.710.625 Transcription Factor Brn-3A D12.776.930.632.625.500 D12.776. ... 930.710.625.500 Transcription Factor Brn-3B D12.776.930.632.625.750 D12.776.930.710.625.750 Transcription Factor Brn-3C D12.776 ... Octamer Transcription Factor-1 D12.776.930.632.500.100 D12.776.930.710.500.100 Octamer Transcription Factor-2 D12.776.930.632. ...
MH DELETED MN ADDED MN
Otx Transcription Factors D12.776.930.621 D12.776.930.650 Ouabain D4.808.155.160.861.600 Outpatient Clinics, Hospital N2.278. ... Transcription Factor Brn-3 D12.776.930.632.625 D12.776.930.710.625 Transcription Factor Brn-3A D12.776.930.632.625.500 D12.776. ... 930.710.625.500 Transcription Factor Brn-3B D12.776.930.632.625.750 D12.776.930.710.625.750 Transcription Factor Brn-3C D12.776 ... Octamer Transcription Factor-1 D12.776.930.632.500.100 D12.776.930.710.500.100 Octamer Transcription Factor-2 D12.776.930.632. ...
MH DELETED MN ADDED MN
Otx Transcription Factors D12.776.930.621 D12.776.930.650 Ouabain D4.808.155.160.861.600 Outpatient Clinics, Hospital N2.278. ... Transcription Factor Brn-3 D12.776.930.632.625 D12.776.930.710.625 Transcription Factor Brn-3A D12.776.930.632.625.500 D12.776. ... 930.710.625.500 Transcription Factor Brn-3B D12.776.930.632.625.750 D12.776.930.710.625.750 Transcription Factor Brn-3C D12.776 ... Octamer Transcription Factor-1 D12.776.930.632.500.100 D12.776.930.710.500.100 Octamer Transcription Factor-2 D12.776.930.632. ...
MH DELETED MN ADDED MN
Otx Transcription Factors D12.776.930.621 D12.776.930.650 Ouabain D4.808.155.160.861.600 Outpatient Clinics, Hospital N2.278. ... Transcription Factor Brn-3 D12.776.930.632.625 D12.776.930.710.625 Transcription Factor Brn-3A D12.776.930.632.625.500 D12.776. ... 930.710.625.500 Transcription Factor Brn-3B D12.776.930.632.625.750 D12.776.930.710.625.750 Transcription Factor Brn-3C D12.776 ... Octamer Transcription Factor-1 D12.776.930.632.500.100 D12.776.930.710.500.100 Octamer Transcription Factor-2 D12.776.930.632. ...
DeCS 2009 - February 20, 2009 version
Oct-1 Transcription Factor use Octamer Transcription Factor-1 Oct-2 Transcription Factor use Octamer Transcription Factor-2 ... Oct-3 Transcription Factor use Octamer Transcription Factor-3 Oct-6 Transcription Factor use Octamer Transcription Factor-6 ... Otx Transcription Factors Ouabain Ouabainum Ouratea use Ochnaceae Ouro Preto Protocol Outbreaks use Disease Outbreaks ...
DeCS 2013 - December 17, 2013 version
Otx Transcription Factors Ouabain Ouabainum Our Ladys Lace use Asperula odorata Ouratea use Ochnaceae ... Oct-1 Transcription Factor use Octamer Transcription Factor-1 Oct-2 Transcription Factor use Octamer Transcription Factor-2 ... Oct-3 Transcription Factor use Octamer Transcription Factor-3 Oct-6 Transcription Factor use Octamer Transcription Factor-6 ...
DeCS 2012 - February 22, 2012 version
Otx Transcription Factors Ouabain Ouabainum Our Ladys Lace use Asperula odorata Ouratea use Ochnaceae ... Oct-1 Transcription Factor use Octamer Transcription Factor-1 Oct-2 Transcription Factor use Octamer Transcription Factor-2 ... Oct-3 Transcription Factor use Octamer Transcription Factor-3 Oct-6 Transcription Factor use Octamer Transcription Factor-6 ...