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*  JCVI: miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2.
Osteoblast-specific gain- and loss-of-function experiments performed in vivo revealed that miR-34b and -c affected ... First, they inhibited osteoblast proliferation by suppressing Cyclin D1, CDK4, and CDK6 accumulation. Second, they inhibited ... miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. ... A screen of microRNAs preferentially expressed in osteoblasts identified members of the miR-34 family as regulators of ...
http://www.jcvi.org/cms/publications/listing/abstract/article/mir-34s-inhibit-osteoblast-proliferation-and-differentiation-in-the-mouse-by-targeting-satb2/
*  FRI0054 IL-6 negatively regulates osteoblast differentiation through ERK pathway in vitro | Annals of the Rheumatic Diseases
Methods Osteoblast differentiation was induced in murine MC3T3-E1 osteoblastic cells with or without addition of IL-6 (soluble ... Objectives The objectives of this study was to clarify the effect of IL-6 on osteoblast differentiation in vitro, with ... Conclusions IL-6 can be thought to negatively regulate osteoblast differentiation through ERK pathway. On the other hand, STAT3 ... However, previous reports regarding the effects of IL-6 on osteoblast differentiation in vitro are not consistent. ...
http://ard.bmj.com/content/71/Suppl_3/327.2
*  Tenascin in bone morphogenesis: expression by osteoblasts and cell type-specific expression of splice variants | Journal of...
In primary osteoblast-enriched cultures, extracellular tenascin was found only in cell aggregates expressing the osteoblast ... Tenascin was secreted into the medium and deposited in the matrix by human and rat osteoblast-like cell lines, as well as by ... Chicken osteoblast cultures synthesized almost exclusively the largest tenascin subunit, whereas fibroblast cultures from ... Within osteogenic regions, tenascin mRNA was expressed by osteoblasts. A comparison of in situ hybridization and ...
http://jcs.biologists.org/content/103/3/765
*  Strontium can increase some osteoblasts without increasing hematopoietic stem cells. - Nuffield Department of Orthopaedics,...
Despite the changes in osteoblast numbers, no increment in the number of N-cadherin(+) osteoblasts and N-cadherin transcripts ... Manipulating osteoblast numbers results in a parallel change in HSC numbers. We tested the activity of strontium (Sr), a bone ... In vitro treatment of primary murine osteoblasts with Sr increased their ability to form bone nodules, and in vivo it increased ... Therefore, increasing the overall number and function of osteoblasts without increasing N-cadherin(+) cells is not sufficient ...
https://www.ndorms.ox.ac.uk/publications/223518
*  The impact of bisphosphonates on the osteoblast proliferation and Collagen gene expression in vitro | Head & Face Medicine |...
... but also by a direct stimulation of osteoblast and osteoblast precursor cells by applying nitrogen-containing bisphosphonates [ ... Zoledronate also caused osteoblasts to increase their gene expression to a maximum level of 330% on day 2. After 14 days of ... Human hip bone osteoblasts (HOB-c, Promo Cell, Heidelberg, Germany) between passages 5-9 were cultured at a density of 200 000 ... Human osteoblast obtained from hip bone were stimulated with zoledronate, ibandronate and clodronate at concentrations of 5 × ...
https://head-face-med.biomedcentral.com/articles/10.1186/1746-160X-6-12
*  Osteoblast - Wikipedia
The osteoblasts are also connected by gap junctions, small pores that connect osteoblasts, allowing the cells in one cohort to ... Osteoblasts are the major cellular component of bone. Osteoblasts arise from mesenchymal stem cells (MSC). MSC give rise to ... Osteoblasts buried in the matrix are called osteocytes. During bone formation, the surface layer of osteoblasts consists of ... A group of organized osteoblasts together with the bone made by a unit of cells is usually called the osteon. Osteoblasts are ...
https://en.wikipedia.org/wiki/Osteoblast
*  Osteoblast milk protein - Wikipedia
Osteoblast milk protein (OMP, Chinese: 造骨牛奶蛋白) is the name used by Mengniu, a Chinese dairy company, for a milk protein used as ... It is supposed to help the absorption of calcium and promote bone growth in the osteoblasts and prevent osteoporosis. In ...
https://en.wikipedia.org/wiki/Osteoblast_milk_protein
*  Osteoblasts Are Bone Idle Without Frizzled-9 - Redorbit
Fzd9-null osteoblasts differentiated normally, but they failed to mineralize their extracellular matrix. The loss of Fzd9 ... Adult bones are maintained by a balance of bone-forming osteoblasts and bone-resorbing osteoclasts. Although Wnt signaling ... A team of researchers led by Thorsten Schinke found that the Wnt receptor Fzd9 was upregulated during osteoblast ... Though little is known about Isg15's function, restoring its expression in Fzd9-null osteoblasts boosted matrix mineralization ...
http://www.redorbit.com/news/health/2011952/osteoblasts_are_bone_idle_without_frizzled9/
*  WikiGenes - Osteoblasts
Analytical, diagnostic and therapeutic context of Osteoblasts. *The cells were identified as functional osteoblasts by indirect ... Anatomical context of Osteoblasts. *Although immature osteoblasts, which expressed alkaline phophatase weakly but not ... Gene context of Osteoblasts. *Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation [25]. ... ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Yang, X., ...
https://www.wikigenes.org/e/mesh/e/2515.html
*  Human Osteoblasts Osteoarthritis | China-Mainland | Sigma-Aldrich
Pipette 30 ml of Human Osteoblast Growth Medium (417-500) to a T-175 flask (SIAL1080) (to be used in Section IV C Step 15.) ... Pipette 15 ml of Human Osteoblast Growth Medium (417-500)* to a T-75 flask (SIAL0641).. * Keep the medium to surface area ratio ... Remove Human Osteoblast Differentiation Medium (417D-250) from culture tissue ware by aspiration. Do not allow cells to dry ... Resuspend the cells in 5 ml of Human Osteoblast Growth Medium (417-500) by gently pipetting the cells to break up the clumps. ...
https://www.sigmaaldrich.com/china-mainland/zh/technical-documents/protocols/biology/human-osteoblasts-osteoarthritis.html
*  Bone voyage-Osteoblasts remotely control tumors | Science
Tumor-driven systemic activation of osteoblasts in the bone promotes lung tumor growth ... Tumor-driven systemic activation of osteoblasts in the bone promotes lung tumor growth ... report that osteoblasts, which reside in the bone, can be remotely activated by secreted factors from lung adenocarcinoma, ...
http://science.sciencemag.org/content/358/6367/1127
*  osteoblasts Cells | Thermo Fisher Scientific - JP
Maintaining healthy cells is the key to experimental success and reproducible research results. To give you confidence in the health of your cells every step of the way, we've highlighted the technologies and products within cell biology that are critical to maintaining optimal cell health. No matter how you are using your cells, you can count on these products to help keep them healthy.. ...
https://www.thermofisher.com/jp/en/home/technical-resources/cell-lines/o/cell-lines-detail-304.html
*  Bone | Bone | Osteoblast
K+ osteoblast .. Bone turnover Osteoclast precursors Proliferate and fuse to Form Osteoclast Hydrogen Ion Remove mineralisation ... RANK ligand and Osteoprotegerin Osteoblast RANK ligand Osteoprotegerin(OPG) (Receptor activator of Nuclear factor kB) for bind ... of OC synthesized from osteoblast is released in circulation Synthesis stimulated by vit-D Excreted by kidney Half life is 5 ... 4/19/12 Lysosomal enzyme digest metrix matrix bone lining cell Osteoblast . ...
https://www.scribd.com/presentation/66806276/Bone
*  Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway
... Ling-juan Liu,1 Li-qun Liu,1 Tao Bo,1 Shi-jun Li,1 ... J. M. Hock, V. Krishnan, J. E. Onyia et al., "Osteoblast apoptosis and bone turnover," Journal of Bone and Mineral Research, ... H. Xie, L. Q. Yuan, X. H. Luo et al., "Apelin suppresses apoptosis of human osteoblasts," Apoptosis, vol. 12, no. 1, pp. 247- ... N. Maruotti, A. Corrado, A. Neve, and F. P. Cantatore, "Bisphosphonates: effects on osteoblast," European Journal of Clinical ...
https://www.hindawi.com/journals/ije/2013/786574/ref/
*  Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway
... the role of puerarin on osteoblast apoptosis and its underlying mechanism of action are still unclear. As we know osteoblasts ... Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway. Ling-juan Liu,1 Li-qun Liu,1 Tao Bo,1 Shi-jun Li,1 ... J. M. Hock, V. Krishnan, J. E. Onyia et al., "Osteoblast apoptosis and bone turnover," Journal of Bone and Mineral Research, ... suggesting that puerarin might regulate osteoblast proliferation and differentiation to promote bone formation in osteoblast ...
https://www.hindawi.com/journals/ije/2013/786574/
*  Osteoblasts | OMICS Publishing Group | Endocrinology And Metabolic Syndrome
Human cultured female osteoblasts (Obs) respond age-dependently to estradiol-17β (E2) and to phytoestrogens by increased DNA ... Osteoblasts. Human cultured female osteoblasts (Obs) respond age-dependently to estradiol-17β (E2) and to phytoestrogens by ...
https://www.omicsonline.org/endocrinology-metabolic-syndrome/osteoblasts.php
*  Osteoblast - Biology-Online Dictionary
Osteoblasts that become trapped in their own secretions become the osteocytes. The osteoblasts work closely with the ... noun, plural: osteoblasts A type of bone cell that arises from fibroblasts, and upon maturity, becomes associated bone ... However, individual osteoblasts cannot make bone, rather, they function as groups and connect with each other to form bone. ... While osteoblasts are associated with bone formation, the osteoclasts are associated with bone resorption. This goes to show ...
https://www.biology-online.org/dictionary/Osteoblast
*  IJMS | Free Full-Text | Ascorbic Acid Attenuates Senescence of Human Osteoarthritic Osteoblasts
... cellular senescence of bone-resident osteoblasts (OB) remains poorly explored. Since oxidative stress is a well-known inducer ... Keywords: osteoblast; osteoarthritis; oxidative stress; senescence; subchondral bone; transcriptomics osteoblast; ... Ascorbic Acid Attenuates Senescence of Human Osteoarthritic Osteoblasts. Maximilian G. Burger 1,2,†. ... "Ascorbic Acid Attenuates Senescence of Human Osteoarthritic Osteoblasts." Int. J. Mol. Sci. 18, no. 12: 2517. ...
http://www.mdpi.com/1422-0067/18/12/2517
*  Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils | Science
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. By Camilla Engblom, Christina Pfirschke ... Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. By Camilla Engblom, Christina Pfirschke ... The activated osteoblasts in turn triggered production of a certain type of neutrophil that infiltrates the primary tumor and ... In turn, these osteoblasts supply tumors with SiglecFhigh neutrophils, which exhibit cancer-promoting functions (left). By ...
http://science.sciencemag.org/content/358/6367/eaal5081
*  Prohibitins, novel vitamin K2 target factors in osteoblast
... novel vitamin K2 target factors in osteoblast. Journal of Biosciences and Medicines, 1, 1-4. doi: 10.4236/jbm.2013.13001. ...
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=40690
*  PLOS Genetics: Systems Genetic Analysis of Osteoblast-Lineage Cells
The goal of this study was to increase our understanding of how genes are organized into networks in osteoblasts. Towards this ... We used the knowledge of this network to identify novel genes that are important for regulating various aspects of osteoblast ... These data improve our understanding of the gene networks operative in cells of the osteoblast-lineage. ... Author Summary The osteoblast-lineage consists of a range of cells from osteogenic precursors that mature into bone-forming ...
https://journals.plos.org/plosgenetics/article/figure?id=10.1371/journal.pgen.1003150.g005
*  What does osteoblast mean?
Meaning of osteoblast. What does osteoblast mean? Information and translations of osteoblast in the most comprehensive ... Definition of osteoblast in the Definitions.net dictionary. ... Search for osteoblast on Amazon. *Search for osteoblast on ... Osteoblast. Osteoblasts are mononucleate cells that are responsible for bone formation; in essence, osteoblasts are specialized ... What does osteoblast mean?. Definitions for osteoblastˈɒs ti əˌblæst. Here are all the possible meanings and translations of ...
http://www.definitions.net/definition/osteoblast
*  TAF, a Tenofovir Prodrug, Not Preferentially Loaded or Toxic in Osteoblasts
... and osteoblasts (0.395 uM). Furthermore, TAF concentrations similar to those given to humans were not toxic to osteoblasts. ... They then evaluated similar TAF concentrations in primary osteoblasts. Next the Gilead team developed a primary osteoblast cell ... In primary osteoblasts, a single 2-hour pulse of the same TAF concentrations yielded TFV-DP levels comparable to those reached ... They assessed cell viability after treating primary osteoblasts with TAF for 3 days. A 2-hour TAF pulse in PBMCs at ...
http://natap.org/2013/ICAAC/ICAAC_06.htm
*  Osteoclasts Control Osteoblast Chemotaxis via PDGF-BB/PDGF Receptor Beta Signaling
... exhibit a reduced capability of attracting osteoblasts. Conversely, osteoblasts whose platelet-derived growth factor receptor β ... Conclusions/Significance We conclude that, in vitro mature osteoclasts control osteoblast chemotaxis via PDGF-bb/PDGFR-β ... Several studies have now described the molecular mechanisms by which osteoblasts control osteoclastogenesis and bone ... secrete chemotactic factors recognized by both mature osteoblasts and their precursors. Several growth factors whose expression ...
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003537
*  JCI - Parathyroid hormone regulates fates of murine osteoblast precursors in vivo
Teriparatide suppresses osteoblast apoptosis (3) and activates dormant bone-lining cells so that they become active osteoblasts ... Teriparatide increases osteoblast numbers by suppressing osteoblast apoptosis and activating bone-lining cells. No direct ... In this way, the action of teriparatide on osteoblast precursors resembles that of PTH on mature osteoblasts. ... probable markers of some early cells in the osteoblast lineage (6, 9) or Ocn-GFPtpz (osteoblast marker). To answer this ...
https://jci.org/articles/view/91699