PROTO-ONCOGENE PROTEINS C-ERBB-2. RECEPTOR, ERBB-2. PROTO-ONCOGENE PROTEINS C-KIT. PROTO-ONCOGENE PROTEIN C-KIT. ... RECEPTORS, INSULIN-LIKE-GROWTH-FACTOR II. RECEPTOR, IGF TYPE 2. RECEPTORS, MACROPHAGE COLONY-STIMULATING FACTOR. RECEPTOR, ... RECEPTORS, INSULIN-LIKE-GROWTH FACTOR I. RECEPTOR, IGF TYPE 1. ... PROTO-ONCOGENE PROTEINS C-MET. PROTO-ONCOGENE PROTEIN C-MET. ... RECEPTORS, EPIDERMAL GROWTH FACTOR-UROGASTRONE. RECEPTOR, EPIDERMAL GROWTH FACTOR. RECEPTORS, INSULIN. RECEPTOR, INSULIN. ...
PROTO-ONCOGENE PROTEINS C-ERBB-2. RECEPTOR, ERBB-2. PROTO-ONCOGENE PROTEINS C-KIT. PROTO-ONCOGENE PROTEIN C-KIT. ... RECEPTORS, INSULIN-LIKE-GROWTH-FACTOR II. RECEPTOR, IGF TYPE 2. RECEPTORS, MACROPHAGE COLONY-STIMULATING FACTOR. RECEPTOR, ... RECEPTORS, INSULIN-LIKE-GROWTH FACTOR I. RECEPTOR, IGF TYPE 1. ... PROTO-ONCOGENE PROTEINS C-MET. PROTO-ONCOGENE PROTEIN C-MET. ... RECEPTORS, EPIDERMAL GROWTH FACTOR-UROGASTRONE. RECEPTOR, EPIDERMAL GROWTH FACTOR. RECEPTORS, INSULIN. RECEPTOR, INSULIN. ...
PROTO-ONCOGENE PROTEINS C-ERBB-2. RECEPTOR, ERBB-2. PROTO-ONCOGENE PROTEINS C-KIT. PROTO-ONCOGENE PROTEIN C-KIT. ... RECEPTORS, INSULIN-LIKE-GROWTH-FACTOR II. RECEPTOR, IGF TYPE 2. RECEPTORS, MACROPHAGE COLONY-STIMULATING FACTOR. RECEPTOR, ... RECEPTORS, INSULIN-LIKE-GROWTH FACTOR I. RECEPTOR, IGF TYPE 1. ... PROTO-ONCOGENE PROTEINS C-MET. PROTO-ONCOGENE PROTEIN C-MET. ... RECEPTORS, EPIDERMAL GROWTH FACTOR-UROGASTRONE. RECEPTOR, EPIDERMAL GROWTH FACTOR. RECEPTORS, INSULIN. RECEPTOR, INSULIN. ...
PROTO-ONCOGENE PROTEINS C-ERBB-2. RECEPTOR, ERBB-2. PROTO-ONCOGENE PROTEINS C-KIT. PROTO-ONCOGENE PROTEIN C-KIT. ... RECEPTORS, INSULIN-LIKE-GROWTH-FACTOR II. RECEPTOR, IGF TYPE 2. RECEPTORS, MACROPHAGE COLONY-STIMULATING FACTOR. RECEPTOR, ... RECEPTORS, INSULIN-LIKE-GROWTH FACTOR I. RECEPTOR, IGF TYPE 1. ... PROTO-ONCOGENE PROTEINS C-MET. PROTO-ONCOGENE PROTEIN C-MET. ... RECEPTORS, EPIDERMAL GROWTH FACTOR-UROGASTRONE. RECEPTOR, EPIDERMAL GROWTH FACTOR. RECEPTORS, INSULIN. RECEPTOR, INSULIN. ...
PROTO-ONCOGENE PROTEINS C-ERBB-2. RECEPTOR, ERBB-2. PROTO-ONCOGENE PROTEINS C-KIT. PROTO-ONCOGENE PROTEIN C-KIT. ... RECEPTORS, INSULIN-LIKE-GROWTH-FACTOR II. RECEPTOR, IGF TYPE 2. RECEPTORS, MACROPHAGE COLONY-STIMULATING FACTOR. RECEPTOR, ... RECEPTORS, INSULIN-LIKE-GROWTH FACTOR I. RECEPTOR, IGF TYPE 1. ... PROTO-ONCOGENE PROTEINS C-MET. PROTO-ONCOGENE PROTEIN C-MET. ... RECEPTORS, EPIDERMAL GROWTH FACTOR-UROGASTRONE. RECEPTOR, EPIDERMAL GROWTH FACTOR. RECEPTORS, INSULIN. RECEPTOR, INSULIN. ...
PROTO-ONCOGENE PROTEINS C-ERBB-2. RECEPTOR, ERBB-2. PROTO-ONCOGENE PROTEINS C-KIT. PROTO-ONCOGENE PROTEIN C-KIT. ... RECEPTORS, INSULIN-LIKE-GROWTH-FACTOR II. RECEPTOR, IGF TYPE 2. RECEPTORS, MACROPHAGE COLONY-STIMULATING FACTOR. RECEPTOR, ... RECEPTORS, INSULIN-LIKE-GROWTH FACTOR I. RECEPTOR, IGF TYPE 1. ... PROTO-ONCOGENE PROTEINS C-MET. PROTO-ONCOGENE PROTEIN C-MET. ... RECEPTORS, EPIDERMAL GROWTH FACTOR-UROGASTRONE. RECEPTOR, EPIDERMAL GROWTH FACTOR. RECEPTORS, INSULIN. RECEPTOR, INSULIN. ...
Proto-Oncogene Proteins/genetics, Proto-Oncogenes, Receptor, ErbB-2", ... In: Oncogene, Vol. 5, Nr. 4, 04.1990, blz. 497-503.. Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review ...
Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular ... Cloning and characterization of T cell receptors (TCRs) from responding T cells resulted in the identification of the two HLA-A ... Due to lack of the receptors for targeted approaches, patients with TNBC have a poor outcome [2]. Conventional chemo- and ... IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005; ...
Receptor, erbB-2. dc.subject. Proto-Oncogene Proteins c-myc. dc.subject. Antineoplastic Agents. ...
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene ... Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for ... Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation ... Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function ...
Localized adenocarcinoma of the lung: oncogene expression of erbB-2 and p53 in 150 patients. June 01, 1995. Clinical Cancer ... M6P/IGF2 receptor: a candidate breast tumor suppressor gene. May 02, 1996. Oncogene ... The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that ... Estrogen receptor alpha (ESR1) mutant A908G is not a common feature in benign and malignant proliferations of the breast. May ...
Order anti-Anti-HER2 c-erbB-2 Rabbit Monoclonal Antibody 01012195040 at Gentaur Anti-HER2 (c-erbB-2) Monoclonal ... HER2 is an oncogene and overexpression of unaltered HER2 coding sequences in NIH 3T3 cells results in cellular transformation ... HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor ... A peptide corresponding to the C-terminus of Human c-erbB-2/HER-2 ... anti-Anti-HER2 (c-erbB-2), Rabbit Monoclonal Antibody. Catalog ...
Lymph node, epidermal growth factor receptor, and estrogen receptor status, tumor size, and histological grade also had ... Expression of the c-erbB-2 oncoprotein appears to be an important independent indicator of prognosis in human breast cancer. ... Positive staining was correlated with negative estrogen receptor status and high histological grade, but there was no ... tissue from 185 primary breast carcinomas were stained immunohistochemically using a polyclonal antibody against the c-erbB-2 ...
... estrogen receptor or progesterone receptor status, or int-2 amplification. C-myc amplification, and especially a high gene copy ... The c-myc proto-oncogene was analyzed in 311 cases of primary breast cancer, in 8% of which it was found to be amplified, ... C-myc amplification was significantly correlated to a high S-phase fraction and to amplification of the c-erbB-2 proto-oncogene ... usually at moderately increased copy number (2-5 copies). The adjacent pvt gene was co-amplified with c-myc in all tumors ...
They express hormone receptors for estrogen (ERα) and for progesterone... ... Background: HER-2/neu gene is amplified and overexpressed in 15-20% of invasive breast cancers. HER2-positive breast cancers ... have a worse prognosis than HER-2-negative tumors and distinctive clinical features. ... Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor- ...
Proto-Oncogenes, Receptor, ErbB-2, Urinary Bladder Neoplasms ... Expression of c-erbB-2 protein product in bladder cancer. ... Aged, Aged, 80 and over, Female, Humans, Immunohistochemistry, Male, Middle Aged, Proto-Oncogene Proteins, ...
... neuroblastoma/glioblastoma derived oncogene homolog, p185erbB2, receptor tyrosine-protein kinase erbB-2, v-erb-b2 avian ... Neu Oncogene, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, TKR1, Tyrosine kinase-type cell surface receptor HER2, c-erb B2/neu ... ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF ... neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/ ...
Product Sheet: Rabbit anti-Human C-erbB-2 IgG fraction polyclonal antibody. *Catalog # PCA-2100a-9 ... Growth Factors, Cytokines, Receptors and their Antibodies. Subcategory. Polyclonal Antibodies (Cancer/Apoptosis). ... This polyclonal antibody can be used in ELISA (1: 100 dilution), immunocytochemistry (1: 100 dilution) and it recognizes c-erbB ... The overexpression of the erbB-2 proto-oncogene is associated with an aggressive human adenocarcinomas, mainly breast and ...
p185erbB2; Proto-oncogene c-ErbB-2; Metastatic lymph node gene 19 protein; Proto-oncogene Neu; NGL; EC 2.7.10.1; CD340; CD ... This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has ... However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand ... Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ...
It is suggested that the overexpression of c-erbB-2 gene product is unlikely to be as common and as pronounced in colorectal ... Paraffin wax sections of 70 surgically resected colorectal adenocarcinomas were examined for the overexpression of HER2/c-erbB- ... 2 oncoprotein using three different specific antibodies and the avidin-biotin immunoperoxidase technique. The patients included ... Proto-Oncogene Proteins, Proto-Oncogenes, Receptor, ErbB-2, Rectal Neoplasms ...
Protein alternative names Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase- ... Protein names Receptor tyrosine-protein kinase erbB-2 * ... type cell surface receptor HER2, p185erbB2 * Immunogen Purified ...
... profile, educations, publications, research, recent courses, and student works ... C-erbB-2/ HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines. ... The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.. 31:3265-3276. 2012 ... The androgen receptor-lncRNASAT1-AKT-p15 axis mediates androgen-induced cellular senescence in prostate cancer cells.. 41:943- ...
... is a member of the ErbB family of tyrosine kinase receptors that are activated by homo- or hetero-dimerisation with other ErbB ... The epidermal growth factor receptor: from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia. J Clin ... Epidermal growth factor receptor (EGFR). The epidermal growth factor receptor (EGFR or ErbB1 or HER1) belongs to a family of ... DDR2 (discoidin domain receptor 2) is a tyrosine kinase receptor seen in up to 4% of SCC (156). Again DDR2, with collagen as ...
... is a member of the epidermal growth factor receptor family and acts as a proto-oncogene. HER2 is involved in cell growth and is ... also known as c-erbB-2, ...
Quantitative transcriptional control of ErbB receptor signaling undergoes graded to biphasic response for cell differentiation ... Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer. Oncogene 25( ... and Ki-Ras oncogene activity50. ErbB and EGFR signaling were also well represented by the significantly enriched gene sets. ... this could merely be due to a diminished source of general growth signal from the ErbB receptors. ...
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science. 1985; ... The expression of c-erbB-1 and c-erbB-2 in Iranian patients with gastric carcinoma. Pathol Oncol Res. 2002;8:252-256. [PubMed] ... Correlation of c-erbB-2 protein expression and lymph node status in early gastric cancer. Oncology. 1992;49:363-367. [PubMed] ... Overexpression of c-ErbB-2 protein in gastric cancer by immunohistochemical stain. Oncology. 1996;53:192-197. [PubMed] ...
Zhang H, Berezov A, Wang Q et al (2007) Review series ErbB receptors : from oncogenes to targeted cancer therapies. Molecules ... Tan L, Zhang J, Wang Y et al (2022) Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy ... Sette G, Salvati V, Mottolese M et al (2015) Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer ... Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors. Bioorg Chem 78:158- ...
Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the ... RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. ... ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in ... The human c-erbB-2 gene is located at 17q21.2 1 Gene, Homeo Box -- See Genes, Homeobox Genes that encode highly conserved ...
Downregulation in the erbB receptor two with trastuzumab enhanced tumor necrosis factor-related apoptosis by ligand exchange ... Oncogene. 1988, 2:273 277th Drebin JA, Hyperlink VC, Stern DF, Weinberg RA, Greene MI. Open modulating one particular oncogene ... Sensitivity in breast cancer overexpress HER2/neu targeted erbB receptor interaction and activation Exp Cell Res 2005, 304:604 ... Drug-induced ubiquitination and degradation erbB receptor tyrosine kinases. Implications to the treatment method of cancer EMBO ...
An important development in cancer research over the past 2 decades has been the recognition that genetic changes drive the ... PDGF receptor, and insulin-like growth factor receptor are all associated with a poor prognosis. ... ERBB-2), ... Proto-oncogene Activation. Activation of proto-oncogenes is a ... TEL originally was cloned as a fusion of TEL with the gene encoding the platelet-derived growth factor receptor b (PDGFR b); ...