Growth Inhibition of Human Non-Small Lung Cancer Cells H460 By Green Tea and Ginger Polyphenols | Bentham Science
NRG1-ErbB Lost in Translation: A New Paradigm for Lung Cancer?. Current Medicinal Chemistry ... Second-line Treatment of Advanced Non-small Cell Lung Cancer Non-oncogene Addicted: New Treatment Algorithm in the Era of Novel ... Topotecan Is a Substrate for Multidrug Resistance Associated Protein 4. Current Drug Metabolism ... of both extracts and the levels of P53 and Bcl-2 proteins were determined. ...http://www.eurekaselect.com/97017/article?tracking-code=4
FusionGDB: Fusion Gene annotation DataBase - Search
protein-coding. protein-coding. Description. receptor tyrosine-protein kinase erbB-2c-erb B2/neu proteinherstatinhuman ... 2metastatic lymph node gene 19 proteinneuro/glioblastoma derived oncogene homologneuroblastoma/glioblastoma derived oncogene ... Protein feature loci. *BPloci. TotalLen. Protein feature. Protein feature note. - In-frame and not-retained protein feature ... Receptor tyrosine-protein kinase erbB-2. biotech. approved. Hgene. ERBB2. P04626. DB08916. Afatinib. Receptor tyrosine-protein ...https://ccsm.uth.edu/FusionGDB/gene_search_result.cgi?page=page&type=quick_search&quick_search=11909
Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein...
Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein ... Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein ... BACKGROUND: The p185c-erbB-2 growth factor receptor protein tyrosine kinase (PTK) is overexpressed in one third of human breast ... Protein tyrosine phosphatases (PTPs) may balance PTK activity as part of normal growth-regulation pathways. PTP1B is an ...https://scholars.duke.edu/display/pub679763
9/16/12 - 9/23/12 | Market Research Reports at ReportsandReports
B-Protein. PNP. 5'-Nucleotidase. 27. Oncogenes. Abl/abl-bcr. AIB1. BCL-2. BRCA1. CD44. C-fos. C-myb. C-myc. CYP-17. Erb-B. HPC1 ... Gliofibrillary Acid Protein. Neurofilaments. Vimentin. KA 93. Kinases. KP16D3. LAI. Leukocyte Common Antigen. Lewis Antigens. ... The current process of drug development begins with the synthesis of molecules, which targets specific proteins in living cells ... Oncogenes, Growth Factors, Hormones, Colony Stimulating Factors, Lymphokines, Immunohistochemical Stains and others. Buy a copy ...http://reportsandreports.blogspot.fr/2012_09_16_archive.html
A New Target For Anticancer Therapy Biology Essay - High Quality Essay Examples and Educational Materials for Students
... involves the 21-kDa guanine-nucleotide-binding proteins encoded by the ras proto-oncogene, of which H- , N- , and K-ras 4A/4B ... erbB-2 ) , HER3 ( erbB-3 ) , and HER4 ( erbB-4 ) , whose map is to convey extracellular cues directing proliferation, ... mediated signal transduction to mitogen-activated protein kinase ( MAPK ) cascade, G protein-coupled receptor ( GPCR ) - ... The cascade of biochemical events that leads from the EGFR to the activation of the proto-oncogene Ras and, finally, of the ...https://philosophyessays.net/a-new-target-for-anticancer-therapy-biology-essay/
Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells | Biochemical Journal
ErbB, v-erb-b2 erythroblastic leukaemia viral oncogene homologue; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HA, ... mitogen-activated protein kinase; PTK6, protein tyrosine kinase 6; Sam68, Src-associated in mitosis 68 kDa protein; SH, Src ... Hsp90 (heat-shock protein 90) was identified as a PTK6-interacting protein in HEK (human embryonic kidney)-293 cells ... PTK6 [protein tyrosine kinase 6; also known as Brk (breast tumour kinase)] is a non-receptor tyrosine kinase, closely related ...http://www.biochemj.org/content/447/2/313
Copper Peptide Studies on Skin Renewal, Wound Healing and Hair Growth | The Science of Loren Pickart PhD - NEW Book Now...
... these proteins. This results in a condition whereby protein synthesis and deposition is occurring concomitant with protein ... Oncogene. 2005 Feb 3;24(6):1104-10.. Decorin prevents metastatic spreading of breast cancer.. Reed CC, Waterhouse A, Kirby S, ... Decorin binds to and modulates the signaling of the epidermal growth factor receptor and other members of the ErbB family of ... Studies the protein albumin and various small molecules associated with the protein.. Expected cause - The effects were due to ...http://www.skinbiology.com/copperpeptideregeneration.html
Androgen receptor - The Full Wiki
2002). "Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1". Oncogene (England) 21 (36 ... 2000). "ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in ... CREB binding protein, TGFB1I1, Caveolin 1, Nuclear receptor coactivator 2, ... Protein inhibitor of activated STAT2, PRPF6, SVIL, NCOA6, Beta-catenin, ...http://www.thefullwiki.org/Androgen_receptor
Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human...
... and protein concentration was quantified by the BCA protein assay kit. An aliquot (30 µg) of the total cellular proteins from ... Oncogene. 1995, 10: 775-778.PubMedGoogle Scholar. *. Bartkova J, Lukas J, Muller H, Lutzhoft D, Strauss M, Bartek J: Cyclin D1 ... by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2 ... Oncogene. 2005, 24: 4370-4379. 10.1038/sj.onc.1208626.View ArticlePubMedGoogle Scholar. ...https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-11-129/
AKT/protein kinase B associates with β-actin in the nucleus of melanoma cells | Bioscience Reports
2003) Autocrine signalling through erbB receptors promotes constitutive activation of protein kinase B/Akt in breast cancer ... 2016) Power of PTEN/AKT: Molecular switch between tumor suppressors and oncogenes. Oncol. Lett. 12, 375-378 doi:10.3892/ol. ... protein kinase B. Introduction. The serine-threonine kinase AKT (also named protein kinase B, PKB) is a critical regulator of ... Abbreviations: ABP, actin-binding protein; CTD, carboxy terminal domain; CREB, cAMP response elemento-binding protein; DSP, ...http://www.bioscirep.org/content/39/1/BSR20181312
Naturopathic Causes and Treatment of Cancer
HER2 is member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. It is a cell ... It is an oncogene. An oncogene turns on cancer.. It works in combination with ILGF. Basically IGF + HER2 =, Increases RTKs / ... Inhibit proteinases therefore oncogenes. An oncogene is a gene in a virus that makes cells become malignant.. Nuts and seeds, ... Protein kinases can become mutated, stuck in the "on" position, and cause unregulated growth of the cell, which is a necessary ...https://www.carahealth.com/health-conditions-a-to-z/lymphatic-system/lymphoma/280-naturopathic-causes-of-cancer32.html
Oral targeted therapy for cancer | Australian Prescriber
BRAF Intracellular protein kinase that forms part of the mitogen-activated protein (MAP) kinase pathway and drives cell ... BCR-ABLBCR = breakpoint cluster region, ABL = abelson murine leukemia oncogene-1 (BCR-ABL is a fusion gene created by the ABL1 ... EGFR Epidermal growth factor receptor (member of the ErbB family of receptors that promotes cell proliferation) ... mTOR Mammalian target of rapamycin (protein kinase that regulates cell growth) VEGF Vascular endothelial growth factor (protein ...https://www.nps.org.au/australian-prescriber/articles/oral-targeted-therapy-for-cancer-5
KAKEN - Research Projects | がん遺伝子の機能解析 (KAKENHI-PROJECT-03258203)
Publications] Tsuneo Saga: 'Imaging of c‐erbB‐2 gene product:in vivo application of anti‐c‐erbB‐2 protein antibody' Cancer Res. ... Publications] Yumiko Matsuzawa: 'Characterization of the promoter region of the yes‐protooncogene' Oncogene. 6. 1561-1568 (1991 ... ステロイドホルモンがErbBー2蛋白質に直接結合して、そのキナ-ゼ活性を亢進させること、そしてErbBー2蛋白質の標的蛋白質としてPIー3キナ-ゼと蛋白質とキナ-ゼ活性を有する分子を予備的に見いだしているhttps://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03258203/
Lund University Publications
Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer Englund, E LU ; Bartoschek, ... Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling Bancovik, Jasna; Moreira, Dayson F; ... 2016) In Oncogene 35(43). p.5585-5596 Mark *2015. * * Thesis Doctoral Thesis (compilation) ...https://lup.lub.lu.se/search/publication?q=keywords+exact+%22Gene+Expression+Profiling%22
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma:...
This panel of proteins may be of value as biomarkers of the pharmacological and clinical activity of sunitinib in RCC, and of ... Sunitinib treatment in advanced RCC patients leads to modulation of plasma levels of circulating proteins involved in VEGF ... potential biomarkers of sunitinib pharmacological activity via serial assessment of plasma levels of four soluble proteins from ... A soluble protein related to the HER-2 proto-oncogene product is released from human breast carcinoma cells. Oncogene. 1991, 6 ...https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-5-32
ErbB. erythroblastosis oncogene B. EGFR (ErbB1). epidermal growth factor receptor. FACS. fluorescence-activated cell sorter. ... Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog. FYN. Fgr/Yes related novel protein. HCK. hemopoietic cell kinase ... 1998) Tec is involved in G protein-coupled receptor- and integrin-mediated signalings in human blood platelets. Oncogene 16: ... lymphocyte-specific protein tyrosine kinase. LYN. Lck/Yes novel. PBMC. peripheral blood mononuclear cell. PBS. phosphate- ...http://jpet.aspetjournals.org/content/363/2/240
Anti-Wheat (Triticum) ERBB3 Antikörper für Immunohistochemistry (Frozen Sections) (IHC (fro))
Family: Protein Kinase. Synonyms: ERBB3, C-erbB-3, C-erbB3, ErbB-3, HER3, p85-sErbB3, p45-sErbB3, MDA-BF-1, ErbB3-S, LCCS2, ... v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) * v-erb-b2 avian erythroblastic leukemia viral oncogene ... Wheat germ lectin purified c-erb B-3 protein.. Type of Immunogen: Purified protein ... V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Andere Bezeichnung HER3 / ERBB3 (ERBB3 Antibody ...http://www.antikoerper-online.de/rtk-signalweg-pathway-8/erbb3-antibody-16057/wheat-ihc-fro-36116/
SMART: RasGEF domain annotation
Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. ... ErbB signaling pathway. 3.72. map05214. Glioma. 3.72. map04810. Regulation of actin cytoskeleton. ... Cell biology depends on the interactions of macromolecules, such as protein-DNA, protein-protein or protein-nucleotide ... Click on the protein counts, or double click on taxonomic names to display all proteins containing RasGEF domain in the ...http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=RasGEF
immunohistochemistry-applications-breast-cancer | China-Mainland | Sigma-Aldrich
The sequence of the neu oncogene was homologous to the erb-B oncogene and its 185kD phosphoprotein was antigenetically related ... Biomarkers expressed by basal-like breast cancers include CK 5&6, CK 14, CK 17, laminin, EGFR, fatty acid binding protein, p16 ... Positivity for S100 protein alone is of limited value since, as we previously mentioned, it can be expressed in both benign and ... GATA binding protein 3 (GATA3) is among the most promising of immunomarkers.4 ...https://www.sigmaaldrich.com/china-mainland/zh/technical-documents/articles/white-papers/immunohistochemistry-applications-breast-cancer.html
Marcelle Winget | Stanford Medicine Profiles
The HER2/c-erbB-2 gene encodes the epidermal growth factor receptorlike human homolog of the rat neu oncogene. Amplification of ... The proto-oncogene HER2/neu encodes a protein tyrosine kinase (p185HER2) that is homologous to the human epidermal growth ... points where x is the protein mass divided by the number of charges introduced by ionization and y is the protein intensity of ... Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the ...https://med.stanford.edu/profiles/marcelle-winget
Ephrin A4 - Wikipedia
1995). "Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins". Oncogene. 10 ... Three transcript variants that encode distinct proteins have been identified. References. *^ a b c GRCh38: Ensembl ... Binding proteins: IGFBP (1, 2, 3, 4, 5, 6, 7). *Cleavage products/derivatives with unknown target: Glypromate (GPE, (1-3)IGF-1) ... protein binding. • ephrin receptor binding. Cellular component. • anchored component of membrane. • plasma membrane. • integral ...https://en.wikipedia.org/wiki/EFNA4
Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1transgenic mice | Genome Biology | Full Text
... others seem to be common to tumors induced by both Neu and Wnt-1 oncogenes. We described gene-expression patterns associated ... In addition, using proteins as markers of cell phenotypes, we showed that initiating oncogenes determine the developmental ... Olayioye MA, Neve RM, Lane HA, Hynes NE: The ErbB signaling network: receptor heterodimerization in development and cancer. ... Proteins in resulting supernatant (25 μg protein) were denatured using 2-mercaptoethanol, resolved on 10% polyacrylamide mini- ...https://genomebiology.biomedcentral.com/articles/10.1186/gb-2005-6-10-r84
Methods and compositions for modulating hyperstabilized c-met - Patent # 8536118 - PatentGenius
Liu et al., "Overexpression of C-met Proto-Oncogene But Not Epidermal Growth Factor Receptor or C-erbB-2 in Primary Human ... Pelicci et al., "The Motogenic and Mitogenic Responses to HGF are Amplified by the Shc Adaptor Protein" Oncogene 10:1631-1638 ( ... Marmor et al., "Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases" Oncogene 23:2057-2070 ( ... Furge et al., "Met Receptor Tyrosine Kinase: Enhanced Signaling Through Adapter Proteins" Oncogene 19:5582-5589 (2000). cited ...http://www.patentgenius.com/patent/8536118.html
Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by...
... general Drug resistance Drug therapy Pharmacogenetics Pharmacogenomics Tumor proteins Tumors ... oncogene homolog B (ras related; GTP binding protein) 0.462 NQOl NAD(P)H Serves as quinone dehydrogenase, reductase involved ... Untangling the ErbB signalling network. Nat. Rev. Mol. Cell. Biol. 2,127-137. Zeino, M., Zhao, Q., Eichhorn, T., Hermann, J., ... DNA repair protein complementation group A -0.526 XP05 Exportin 5 Nuclear export of proteins -0.522 RPS21 Ribosomal protein ...https://www.thefreelibrary.com/Cytotoxicity+of+the+bisphenolic+honokiol+from+Magnolia+officinalis+...-a0390869305
The role of hormonal therapy in the management of hormonal-receptor-positive breast cancer with co-expression of HER2 | Nature...
Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancer. . Br J ... Oncogene 26: 4007-4016. **CAS*Article*Google Scholar*69.. Migliaccio A et al. (2002) Src is an initial target of sex steroid ... Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, ... Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor- ...https://www.nature.com/articles/ncponc1179?error=cookies_not_supported&code=22187c83-84ed-498c-aca6-2a0cd16bfd77