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*  Anti-GTPase HRAS antibody [Y132] (ab32417) | Abcam
Transformation gene oncogene HAMSV antibody. *Transforming protein p21 antibody. *v Ha ras Harvey rat sarcoma viral oncogene ... PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes.. Cell Death Dis 7:e2311 (2016 ... Lysates/proteins at 10 µg per lane.. Secondary. HRP goat anti-rabbit IgG (H+L) at 1/20000 dilution. Observed band size : 21 kDa ... Lysates/proteins at 10 µg per lane.. Secondary. HRP goat anti-rabbit IgG (H+L) at 1/20000 dilution. Observed band size : 21 kDa ...
http://www.abcam.com/gtpase-hras-antibody-y132-ab32417.html
*  HRAS Exon 4 Primer Set (B) - FemtoPath | HongJing弘晉
... p19 H-RasIDX protein; c-has/bas p21 protein; transforming protein p21; Ha-Ras1 proto-oncoprotein; c-ras-Ki-2 activated oncogene ... Ras family small GTP binding protein H-Ras; CTLO; HAMSV; K-RAS; N-RAS; RASH1; C-HRAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1; ... HRAS; v-Ha-ras Harvey rat sarcoma viral oncogene homolog; HRAS1; GTPase HRas; p21ras; H-Ras- 1; ... GTP- and GDP-binding peptide B; transformation gene: oncogene HAMSV; ...
http://femtopath.com/product/hras-exon-4-primer-set-b/
*  SMART: Secondary literature for RAS domain
The crystal structure of the H-ras oncogene protein p21 complexed to the slowly hydrolysing GTP analogue GppNp has been ... The protein R-Ras p21 is about 50% identical to the Ras p21 protooncogene product. This protein is incapable of transforming ... ras p21/ras p21-like small G proteins and their regulatory proteins] ... v-Ha-ras encoded p21 protein (p21V), the cellular c-Ha-ras encoded protein (p21C) and its T24 mutant form p21T were produced in ...
http://smart.embl.de/smart/show_secondary.cgi?domain=RAS
*  K-ras gene | Article about K-ras gene by The Free Dictionary
A gene is, in essence, a segment of DNA that has a particular purpose, i.e., that codes for a... Explanation of K-ras gene ... Find out information about K-ras gene. the structural unit of inheritance in living organisms. ... K-ras gene. *K-Ras Oncogene-Associated Gene. *K-ras p21 protein ... K-ras gene , Article about K-ras gene by The Free Dictionary ... redirected from K-ras gene). Also found in: Dictionary, Thesaurus, Medical.. Related to K-ras gene: KRAS gene,. the structural ...
https://encyclopedia2.thefreedictionary.com/K-ras+gene
*  Resistance to chemotherapeutic agents and promotion of transforming activity mediated by embryonic stem cell-expressed Ras ...
... a novel Ras family protein previously reported as the ... expression and function of embryonic stem cell-expressed Ras ( ... Oncogene Protein p21(ras) / genetics, metabolism*. Phosphatidylinositol 3-Kinases / antagonists & inhibitors, metabolism. ... EC 3.6.5.2/Oncogene Protein p21(ras) ... a novel Ras family protein previously reported as the specific ... 0/Antineoplastic Agents; 0/ERas protein, human; 0/Protein Kinase Inhibitors; 15663-27-1/Cisplatin; 23214-92-8/Doxorubicin; ...
http://www.biomedsearch.com/nih/Resistance-to-chemotherapeutic-agents-promotion/20811723.html
*  EREG | Cancer Genetics Web
Proto-Oncogene Proteins p21(ras). *Intercellular Signaling Peptides and Proteins. *Amphiregulin. *Antineoplastic Agents ... Proteins downregulated in tumors were studied by GO and KEGG pathways enrichment analyses. Six proteins were found both ... Juergens RA, Bratman SV, Tsao MS, et al.. Biology and patterns of response to EGFR-inhibition in squamous cell cancers of the ... protein binding - response to peptide hormone stimulus - wound healing Data from Gene Ontology via CGAP [Hide] ...
http://www.cancerindex.org/geneweb/EREG.htm
*  CD74 | Cancer Genetics Web
Proto-Oncogene Proteins p21(ras). *Immunophenotyping. *Immunohistochemistry. Tag cloud generated 16 March, 2017 using data from ... MHC class II protein binding - MHC class II protein complex - multivesicular body - negative regulation of apoptotic process - ... This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). ... Kirsten rat sarcoma viral oncogene homolog (KRAS), fusions of anaplastic lymphoma kinase (ALK), c-ros oncogene 1 (ROS1), and ...
http://www.cancerindex.org/geneweb/CD74.htm
*  Models illustrating short-term effects of CagA on an ep | Open-i
Oncogene Protein p21(ras)/metabolism. *Signal Transduction. *Wings, Animal. Related in: MedlinePlus ... We further explored the effects of CagA-mediated JNK pathway activation on an epithelium in the context of oncogenic Ras ... We further explored the effects of CagA-mediated JNK pathway activation on an epithelium in the context of oncogenic Ras ... Gastric cancer development is strongly correlated with infection by Helicobacter pylori possessing the effector protein CagA. ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3475654_ppat.1002939.g006&req=4
*  Mice expressing melanocyte lineage NRasQ61K retain pigm | Open-i
Oncogene Protein p21(ras)/genetics*/metabolism. *Skin Neoplasms/metabolism/pathology*. *rac GTP-Binding Proteins/genetics/ ... MAPK/ERK kinase/mitogen-activated protein kinase (MAPK) pathways to enhance proliferation. The Ras oncogene also activates ... MAPK/ERK kinase/mitogen-activated protein kinase (MAPK) pathways to enhance proliferation. The Ras oncogene also activates ... Bottom Line: The Ras oncogene also activates signaling via the related Rho GTPase Rac1, which can mediate growth, survival, and ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3472562_jid2012186f2&req=4
*  acinar carcinoma 2005:2010 - BioMedLib™ search engine
Kras2 protein, mouse; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras) ... Proto-Oncogene Proteins p21(ras) / genetics. *[MeSH-minor] Acinar Cells / enzymology. Animals. Carcinogenesis / metabolism. ... Proto-Oncogene Proteins p21(ras) / metabolism. *[MeSH-minor] Animals. Animals, Genetically Modified. Cell Proliferation. ... Nerve Tissue Proteins; 0 / Neurog3 protein, mouse; 0 / Tumor Suppressor Proteins; 0 / tuberous sclerosis complex 1 protein; EC ...
http://bmlsearch.com/?kwr=acinar%20carcinoma%202005:2010
*  ras Proteins Summary Report | CureHunter
... monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21 ... The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell ... RAS), plays a role in normal cellular growth, differentiation and development. ... GTP-Binding Proteins: 5070*Monomeric GTP-Binding Proteins: 286*ras Proteins: 224*Proto-Oncogene Proteins p21(ras): 108 ...
http://www.curehunter.com/public/keywordSummaryD018631-ras-Proteins.do
*  "Divergent mechanisms for homologous desensitization of p21ras by insul" by Jes K. Klarlund, Andrew D. Cherniack et al.
... and PDGF all cause disassembly of Sos proteins from signaling complexes during p21ras desensitization, but at least two ... Here we show that p21ras is desensitized by insulin in 3T3-L1 adipocytes in the continued presence of activated insulin ... Nonetheless, the desensitization of p21ras in response to these stimuli was homologous, in that each peptide could reactivate [ ... PDGF action triggers both mechanisms of Grb2 disassembly, which probably operate in concert with GAP to attenuate p21ras ...
https://escholarship.umassmed.edu/oapubs/807/
*  Role of Phosphatidylinositol 4,5-Bisphosphate in Ras/Rac-Induced Disruption of the Cortactin-Actomyosin II Complex and...
Oncogene Protein p21(ras) (MeSH) * Phenotype (MeSH) * Phosphatidylinositol 4,5-Diphosphate (MeSH) ... Oncogenic Ras mutants such as v-Ha-Ras cause a rapid rearrangement of actin cytoskeleton during malignant transformation of ... Thus, we propose that PIP2, an end-product of the oncogenic Ras/PI-3 kinase/Rac pathway, serves as a second messenger in the ... Both PI-3 kinase and Rac are required for Ras-induced malignant transformation and membrane ruffling. However, the signal ...
https://scholars.latrobe.edu.au/display/publication23524
*  Extracellular Remodelling During Oncogenic Ras-Induced Epithelial-Mesenchymal Transition Facilitates MDCK Cell Migration
Oncogene Protein p21(ras) (MeSH) * RNA, Messenger (MeSH) published in * Journal of Proteome Research Journal ... MDCK cells undergoing Ras-induced EMT remodel the extracellular matrix (ECM) via diminished expression of basement membrane ... Extracellular Remodelling During Oncogenic Ras-Induced Epithelial-Mesenchymal Transition Facilitates MDCK Cell Migration ... Many of the secretome proteins identified broaden our understanding of the EMT process. ...
https://scholars.latrobe.edu.au/display/publication15068
*  "Disassembly of Son-of-sevenless proteins from Grb2 during p21ras desen" by Andrew D. Cherniack, Jes K. Klarlund et al.
The disassembly of Grb2 from Sos proteins slightly precedes the time course of p21ras deactivation in response to insulin. ... Here we show that in 32P-labeled 3T3-L1 adipocytes the elevated cellular concentrations of [32P]GTP-bound p21ras in response to ... These data are consistent with the hypothesis that the dissociation of Grb2 from Sos proteins caused by insulin in 3T3-L1 cells ... Similarly, anti-Grb2 immunoprecipitates of such lysates revealed the presence of decreased Sos1 protein due to insulin action. ...
https://escholarship.umassmed.edu/oapubs/813/
*  Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are...
Proto-Oncogene Proteins p21(ras). -. dc.title. Host determinants of DNA alkylation and DNA repair activity in human colorectal ... AT transition in the K-ras oncogene.Authors: Jackson PE, Hall CN, O'Connor PJ, Cooper DP, Margison GP, Povey AC. Issue date: ... 23 had K-ras mutations, whereas none of the 7 individuals with cd genotype had a K-ras mutation (P=0.04). No other associations ... 23 had K-ras mutations, whereas none of the 7 individuals with cd genotype had a K-ras mutation (P=0.04). No other associations ...
http://christie.openrepository.com/christie/handle/10541/85754
*  Find NIH Grants - Indiana University School of Medicine
Proto-Oncogene Proteins p21(ras) TISSUE SPECIFIC GENE THERAPY FOR HUMAN PROSTATE CANCER. Kao, C. ...
https://indiana.pure.elsevier.com/en/projects/?format=&page=28
*  BsmI polymorphism in N-ras intron I (RASN). - The Christie Research Publications Repository
Proto-Oncogene Proteins p21(ras). -. dc.title. BsmI polymorphism in N-ras intron I (RASN).. en. ... PCR primers to convert c-Ki-ras to a four allele RsaI system (KRAS2).Authors: Heighway J. Issue date: 1991 Dec 25 ... BsmI polymorphism in N-ras intron I (RASN). 1991, 19 (3):682 Nucleic Acids Res.. Journal:. Nucleic Acids Research. Issue Date: ... BsmI polymorphism in N-ras intron I (RASN).. Authors:. Heighway, Jim. Affiliation:. Department of Cancer Genetics, Christie ...
http://christie.openrepository.com/christie/handle/10541/104753
*  Denigma: Jazwinski SM et al., 2010
Membrane Proteins/*genetics; Middle Aged; Proto-Oncogene Proteins p21(ras)/*genetics; Sphingosine N-Acyltransferase. Journal: ...
http://denigma.de/datasets/reference/2199
*  RAS-associated autoimmune leukoproliferative disorder - Wikipedia
1988). "Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21". Science. 239 (888-893): 888 ... "NEUROBLASTOMA RAS VIRAL ONCOGENE HOMOLOG; NRAS". OMIM. Retrieved 8 April 2014. de Vos AM; Tong L; Milburn MV; et al. ( ... Somatic RAS mutations greatly diminish the GTPase activity within the cell. The reduced GTPase activity locks the cells in an ... NRAS and KRAS are members of the RAS subfamily and are implicated in many types of cancer. Somatic mutations are changes in DNA ...
https://en.wikipedia.org/wiki/RAS-associated_autoimmune_leukoproliferative_disorder
*  Inhibition of PI-3K restores nuclear p27(Kip1) expression in a mouse model of Kras-driven lung cancer. - authors@Fred Hutch
Proto-Oncogene Proteins p21(ras)/genetics/*metabolism; RNA, Messenger/genetics/metabolism; Urethane/pharmacology ... The Ras effector Akt is known to regulate p27 mRNA abundance by phosphorylating and inactivating the FOXO transcription factors ... Urethane-induced lung tumors in mice frequently harbor mutations in the Kras oncogene, and in this study, we use this model to ... Tumors showed a reduced nuclear/cytoplasmic ratio of p27 protein, together with an increase in phosphorylated Thr197 p27 in the ...
http://authors.fhcrc.org/332/
*  List of MeSH codes (D12.776) - Wikipedia
... oncogene protein gp140(v-fms) MeSH D12.776.964.700.750.710 - oncogene protein p21(ras) MeSH D12.776.964.700.750.750 - oncogene ... oncogene protein gp140(v-fms) MeSH D12.776.964.775.750.710 - oncogene protein p21(ras) MeSH D12.776.964.775.750.750 - oncogene ... oncogene protein gp140(v-fms) MeSH D12.776.624.664.520.750.710 - oncogene protein p21(ras) MeSH D12.776.624.664.520.750.750 - ... proto-oncogene proteins c-yes MeSH D12.776.624.664.700.200 - proto-oncogene proteins p21(ras) MeSH D12.776.624.664.700.202 - ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776)
*  adenocarcinoma in situ of thyroid 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Proto-Oncogene Proteins B-raf / genetics. Proto-Oncogene Proteins c-ret / genetics. Proto-Oncogene Proteins p21(ras) / genetics ... Proto-Oncogene Proteins B-raf; EC 3.6.5.2 / HRAS protein, human; EC 3.6.5.2 / Proto-Oncogene Proteins p21(ras); EC 3.6.5.2 / ... RET protein, human; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf; EC 3.6.5.2 / ras Proteins ... Proto-Oncogene Proteins; 0 / Receptors, Cell Surface; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret; EC 2.7.10.1 / RET protein, ...
http://www.bmlsearch.com/?kwr=adenocarcinoma+in+situ+of+thyroid+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Ceprotin Treatment Registry
Oncogene Protein P21(ras). Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can ... also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated ... Protein deficiency may also arise in the face of adequate protein intake if the protein is of poor quality (i.e., the content ... Protein S. The vitamin K-dependent cofactor of activated PROTEIN C. Together with protein C, it inhibits the action of factors ...
https://www.bioportfolio.com/resources/trial/64739/Ceprotin-Treatment-Registry.html