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*  Frontiers | MicroRNAs in the Host Response to Viral Infections of Veterinary Importance | Veterinary Science
... resulted in the reduction of v-myb myeloblastosis viral oncogene homolog-like 1 protein. The study also showed an inhibitory ... Prion Protein-Related Diseases. Prion proteins are the causative agents of bovine spongiform encephalopathy (BSE; "mad cow ... likely via targeting and repressing yes-associated protein 1, cyclin E, and Drosophila inhibitor of apoptosis protein 1 mRNAs ( ... microRNAs as oncogenes and tumor suppressors. Dev Biol (2007) 302(1):1-12. doi:10.1016/j.ydbio.2006.08.028 ...
https://www.frontiersin.org/articles/10.3389/fvets.2016.00086/full
*  Frontiers | Leukemia-Initiating Cells in T-Cell Acute Lymphoblastic Leukemia | Oncology
Core regulatory circuit in T-cell acute lymphoblastic leukemia (T-ALL) (38, 105). TAL1, GATA3, RUNX1, and MYB proteins (circles ... and protein synthesis, including MYC and HES1 (49-53). These studies implicated NOTCH1 as a driver oncogene in T-ALL. ... In T-ALL cells, TAL1 and LMO proteins form a transcriptional complex with E-proteins and GATA3 (103, 104). Their regulatory ... TAL1 (T), GATA3 (G), RUNX1 (R), MYB (M), E-protein (E), LMO1/2 (L). ...
https://www.frontiersin.org/articles/10.3389/fonc.2017.00218/full
*  Frontiers | Targeting TBP-Associated Factors in Ovarian Cancer | Oncology
Herein, we outline a hypothesis that TATA-box binding protein (TBP) associated factors (TAFs), which compose the RNA Polymerase ... Herein, we outline a hypothesis that TATA-box binding protein (TBP) associated factors (TAFs), which compose the RNA Polymerase ... Transactivation mediated by B-Myb is dependent on TAF(II)250. Oncogene (2003) 22(19):2932-41. doi:10.1038/sj.onc.1206494 ... Human TAFII31 protein is a transcriptional coactivator of the p53 protein. Proc Natl Acad Sci U S A (1995) 92(11):5154-8. doi: ...
https://www.frontiersin.org/articles/10.3389/fonc.2014.00045/full
*  Frontiers | Gene Expression and Yeast Two-Hybrid Studies of 1R-MYB Transcription Factor Mediating Drought Stress Response in...
The protein-protein interaction study identified three interacting peptides, a galactinol-sucrose galactosyltransferase 2, a ... The protein-protein interaction study identified three interacting peptides, a galactinol-sucrose galactosyltransferase 2, a ... Subsequently, a candidate single repeat MYB gene (1R-MYB) that was remarkably induced in the drought tolerant genotypes under ... These findings provide preliminary insights into the ability of 1R-MYB TF to co-regulate drought tolerance mechanism in ...
https://www.frontiersin.org/articles/10.3389/fpls.2015.01117/full
*  Frontiers | Insulin/Insulin-Like Growth Factors in Cancer: New Roles for the Aryl Hydrocarbon Receptor, Tumor Resistance...
Oncogene (2012) 31:3213-22. doi:10.1038/onc.2011.495. Pubmed Abstract , Pubmed Full Text , CrossRef Full Text , Google Scholar ... MYB, SRC, JAK2, and JUND1 compared with vehicle (32). Taken together, these data suggest that TCDD inhibits adipo-CM and IGF2 ... We found that IGF2-treated MCF7 cells have higher levels of AHR mRNA and protein than control cells (36). We noted that ... Oncogene (2008) 27:397-403. doi:10.1038/sj.onc.1210636. Pubmed Abstract , Pubmed Full Text , CrossRef Full Text , Google ...
https://www.frontiersin.org/articles/10.3389/fendo.2015.00012/full
*  Frontiers | Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere...
First, TBPs that commonly bind to telomeric DNA include the c-Myb binding proteins, OB-fold single-stranded binding proteins, ... First, TBPs that commonly bind to telomeric DNA include the c-Myb binding proteins, OB-fold single-stranded binding proteins, ... The formation of paralogs that diverge from their progenitor proteins ultimately can form a high frequency of altered TBPs with ... The formation of paralogs that diverge from their progenitor proteins ultimately can form a high frequency of altered TBPs with ...
https://www.frontiersin.org/articles/10.3389/fgene.2016.00010/full
*  Frontiers | Identification of Norway Spruce MYB-bHLH-WDR Transcription Factor Complex Members Linked to Regulation of the...
In addition, we also identified protein-protein interactions among different homologs of MYB, bHLH and WDR. Finally, we ... In addition, we also identified protein-protein interactions among different homologs of MYB, bHLH and WDR. Finally, we ... While MYB transcription factors have been previously shown to control specialized metabolism in gymnosperms, the identity of ... While MYB transcription factors have been previously shown to control specialized metabolism in gymnosperms, the identity of ...
https://www.frontiersin.org/articles/10.3389/fpls.2017.00305/full
*  Frontiers | The Interplay between PP2A and microRNAs in Leukemia | Oncology
PP2A is responsible for modulating function and controlling expression of tumor suppressors such as p53 and oncogenes such as ... PP2A results in failure to turn off survival signaling cascades that drive drug resistance such as those regulated by Protein ... PP2A is responsible for modulating function and controlling expression of tumor suppressors such as p53 and oncogenes such as ... Protein Phosphatase 2A (PP2A) is a serine/threonine phosphatase family whose members have been implicated in tumor suppression ...
https://www.frontiersin.org/articles/10.3389/fonc.2015.00043/full
*  Frontiers | Natural Killer T Cells: An Ecological Evolutionary Developmental Biology Perspective | Immunology
... cells are innate-like T lymphocytes that recognize glycolipid antigens presented by the MHC class I-like protein CD1d. ... cells are innate-like T lymphocytes that recognize glycolipid antigens presented by the MHC class I-like protein CD1d. ... cellular protein homologous to the Rous sarcoma virus oncogene) kinases (protein phosphorylation enzymes) essential for ... Myb, that encodes the transcription factor c-Myb, Rorc, which encodes RORγt, and Tcf12 that codes for HEB) that impair survival ...
https://www.frontiersin.org/articles/10.3389/fimmu.2017.01858/full?utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field=&journalName=Frontiers_in_Immunology&id=319993
*  Frontiers | MicroRNA Regulation of Host Immune Responses following Fungal Exposure | Immunology
miR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell (2007) 131(1):146-59. doi:10.1016/j. ... The cell wall is composed of ergosterol, chitin, glucans, such as (1 → 3)-β-d-glucan, and mannose proteins (2). Fungal ... induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC. ... an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A (2006) 103(33):12481-6. doi: ...
https://www.frontiersin.org/articles/10.3389/fimmu.2018.00170/full
*  Frontiers | Small RNAs Derived from the T-DNA of Agrobacterium rhizogenes in Hairy Roots of Phaseolus vulgaris | Plant Science
... belonging to several oncogenes were detected in hairy roots using high-throughput sequencing. The most abundant and diverse ... belonging to several oncogenes were detected in hairy roots using high-throughput sequencing. The most abundant and diverse ... the 6b protein from the T-DNA region of the Ti plasmid was reported to interact with AGO1 and the SERRATE (SE) protein involved ... carrying the T-DNA oncogenes (Taylor et al., 2006). For years, A. rhizogenes oncogenes have been considered modulators of ...
https://www.frontiersin.org/articles/10.3389/fpls.2017.00096/full
*  Frontiers | Transcriptomic Effects of the Cell Cycle Regulator LGO in Arabidopsis Sepals | Plant Science
Genes activated by LGOoe, directly or indirectly, predominantly encode proteins involved in defense responses, including ... Genes activated by LGOoe, directly or indirectly, predominantly encode proteins involved in defense responses, including ... 2009), of which 788 could be identified with protein-coding genes in TAIR10; and 264 protein-coding genes in TAIR10 that were ... 2005). The Arabidopsis ATR1 Myb transcription factor controls indolic glucosinolate homeostasis. Plant Physiol. 137, 253-262. ...
https://www.frontiersin.org/articles/10.3389/fpls.2016.01744/full
*  Frontiers | HERV-K(HML-2), the Best Preserved Family of HERVs: Endogenization, Expression, and Implications in Health and...
We will then focus on the genes and proteins encoded by HERV-K(HML-2) as well as inactivation of these proviruses by ... We will then focus on the genes and proteins encoded by HERV-K(HML-2) as well as inactivation of these proviruses by ... However some, particularly the most recently acquired proviruses of the HERV-K(HML-2) family, can expresses viral proteins and ... However some, particularly the most recently acquired proviruses of the HERV-K(HML-2) family, can expresses viral proteins and ...
https://www.frontiersin.org/articles/10.3389/fonc.2013.00246/full
*  Frontiers | Comparative Analysis of miRNAs and Their Target Transcripts between a Spontaneous Late-Ripening Sweet Orange Mutant...
MYB transcription factors and pentatricopeptide repeat proteins (PPR genes; Fei et al., 2013; Xia et al., 2015a,b). ... Oncogene 25, 2537-2545. doi: 10.1038/sj.onc.1209283. PubMed Abstract , CrossRef Full Text , Google Scholar ... For instance, seven differential abundance heat shock proteins and 11 differential expression heat shock protein transcripts ... csi-miR3950 was predicted to trigger NAC domain-containing proteins, csi-miR393h triggered two TIR/AFB auxin receptor proteins ...
https://www.frontiersin.org/articles/10.3389/fpls.2016.01416/full
*  Frontiers | An evolutionary perspective on anti-tumor immunity | Oncology
oncogenes alter k's. (. k. p. −. k. d. ). ︷. ⋅. C. T. −. k. d. ⁢. I. ⋅. C. II. ⋅. C. T. ︸. innate immmunity. −. k. d. ⁢. A. ⋅. ... The rules represent fundamental transformations, such as protein--protein interactions or elementary reactions steps, that are ... MYB, TGFB1, IL10, EBI3, IL12A) differentiation (Wei et al., 2009). Macrophage subsets were based upon gene clusters associated ... van Leeuwen, F., and Nusse, R. (1995). Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer. Semin ...
https://www.frontiersin.org/articles/10.3389/fonc.2012.00202/full
*  Frontiers | Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response | Immunology
... such as B lymphocyte-induced maturation protein-1 (Blimp-1). These inducible B cell-intrinsic epigenetic marks guide the ... such as B lymphocyte-induced maturation protein-1 (Blimp-1). These inducible B cell-intrinsic epigenetic marks guide the ... In resting naive and memory B cells, and non-B cells, silencer elements in region II bind the repressor proteins E2f and c-Myb ... Thus, by allowing selected oncogenes to escape regulation by their modulatory miRNAs, the shortening of 3′ UTRs may provide an ...
https://www.frontiersin.org/articles/10.3389/fimmu.2015.00631/full
*  Frontiers | Modeling the Mechanism of GR/c-Jun/Erg Crosstalk in Apoptosis of Acute Lymphoblastic Leukemia | Physiology
... alternative potential mechanism where c-Jun may be an indirect GR target that is controlled via an upstream repressor protein. ... alternative potential mechanism where c-Jun may be an indirect GR target that is controlled via an upstream repressor protein. ... However, the emerging picture is complicated as the activities of genes and proteins involved are controlled by multiple ... However, the emerging picture is complicated as the activities of genes and proteins involved are controlled by multiple ...
https://www.frontiersin.org/articles/10.3389/fphys.2012.00410/full