Increased Bcl2 expression by antisense oligoribonucleotides targeting the ARE motif | Molecular Pharmacology
Increased Bcl2 expression by antisense oligoribonucleotides targeting the ARE motif. Laura Ghisolfi, Laura Papucci, Annamaria ... Increased Bcl2 expression by antisense oligoribonucleotides targeting the ARE motif. Laura Ghisolfi, Laura Papucci, Annamaria ... Increased Bcl2 expression by antisense oligoribonucleotides targeting the ARE motif. Laura Ghisolfi, Laura Papucci, Annamaria ... Increased Bcl2 expression by antisense oligoribonucleotides targeting the ARE motif Message Subject (Your Name) has forwarded a ...http://molpharm.aspetjournals.org/content/early/2005/06/13/mol.105.014357
Synthesis of Oligodeoxyribo‐ and Oligoribonucleotides According to the H‐Phosphonate Method - Current Protocols
Synthesis of oligoribonucleotides by the H‐phosphonate method using base‐labile 2′‐O‐protecting groups. II. Some aspects of use ... Synthesis of Oligodeoxyribo‐ and Oligoribonucleotides According to the H‐Phosphonate Method. Roger Strömberg1, Jacek Stawinski2 ... Synthesis of oligoribonucleotides by the H‐phosphonate approach using base labile 2′‐O‐protecting groups. 5. Recent progress in ... Oligoribonucleotide synthesis with H‐phosphonates. An improved procedure with base labile N‐acyl protection and two alternative ...http://www.currentprotocols.com/WileyCDA/CPUnit/refId-nc0304.html
CA2704853C - Immune stimulatory oligoribonucleotide analogs containing modified oligophosphate moieties - Google...
1mmunostimulatory oligoribonucleotides (ORN) featuring 5'-triphosphates and various 5'-triphosphate analogs are provided. Also ... Oligoribonucleotides that include at least one ribonucleotide analog are also referred to as oligoribonucleotide analogs. The ... 15-oligoribonucleotides which, apart from a 5'-triphosphate or 5'-triphosphate analog, are oligoribonucleotide analogs.. Except ... In one embodiment the oligoribonucleotide is a linear polymer. In one embodiment the oligoribonucleotide is a branched polymer ...https://patents.google.com/patent/CA2704853C/en
Oligoribonucleotides - Semantic Scholar
Oligoribonucleotides. Known as: Oligoribonucleotides [Chemical/Ingredient] A group of ribonucleotides (up to 12) in which the ... Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates.. *James. Milligan, Duncan R. Groebe, Gary W ... We have devised a method to replace the cap structure of a mRNA with an oligoribonucleotide (r-oligo) to label the 5' end of… ( ... Modification of splicing in the dystrophin gene in cultured Mdx muscle cells by antisense oligoribonucleotides. ...https://www.semanticscholar.org/topic/Oligoribonucleotides/288581
Oligoribo-nucleotides, promoters of leucocyte and platelet genesis in animals depleted by anticancer drugs
86 - Oligoribo-nucleotides, promoters of leucocyte and platelet genesis in animals depleted by anticancer drugs. Authors : M. ... Home » 86 - Oligoribo-nucleotides, promoters of leucocyte and platelet genesis in animals depleted by anticancer drugs ...https://www.beljanski.org/engl/beljanski-publications/mirko-beljanskis-publications/86-oligoribo-nucleotides-promoters-of-leucocyte-and-platelet-genesis-in-animals-depleted-by-anticancer-drugs/
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-mediated - Small-Molecule...
For subsets of Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-mediated. For subsets of ... We indeed demonstrate that T1 nanoparticles bind 2OMePS oligoribonucleotides and have a body-wide distribution following IP ... Duchenne muscular dystrophy (DMD) mutations, antisense oligoribonucleotide (AON)-mediated exon skipping has proven to be ...http://researchensemble.com/2017/09/01/for-subsets-of-duchenne-muscular-dystrophy-dmd-mutations-antisense-oligoribonucleotide-aon-mediated/
Prognostic Implications of MicoRNA miR-195 Expression in Human Tongue Squamous Cell Carcinoma
RNA Oligoribonucleotide. The small interfering RNA (siRNA) targeting human Cyclin D1 and Bcl-2 transcripts and siRNA control ...https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056634
Frontiers | A Network of Regulations by Small Non-Coding RNAs: The P-TEFb Kinase in Development and Pathology | Genetics
One most intriguing aspect is the fact that, in ES cells as in the mouse, oligoribonucleotides with fragments of the sense ... No clear phenotype was generated in our hands by a series of oligoribonucleotides tested in the microinjection assay and/or in ... A third avenue of regulation is via activation of transcription by sequence-related oligoribonucleotides that we reported for ... Long Term Transcriptional Activation by Homologous Oligoribonucleotides and microRNAs. A third mode of regulation of Cdk9 ...https://www.frontiersin.org/articles/10.3389/fgene.2011.00095/full
Patent US6271358 - RNA targeted 2′-modified oligonucleotides that are conformationally ... - Google Patents
Oligoribonucleotides and ribonucleases for cleaving RNA. US7749978. Nov 26, 2007. Jul 6, 2010. Alnylam Pharmaceuticals, Inc.. ... Poly-substituted-phenyl-oligoribo nucleotides having enhanced stability and membrane permeability and methods of use. ... Sproat et al., "Novel Solid-Phase Synthesis of Branched Oligoribonucleotides, Including a Substrate for the RNA Debranching ... McGregor et al., "Preparation of Oligoribonucleotides Containing 4-Thiouridine Using Fpmp Chemistry. Photo-Crosslinking to RNA ...http://www.google.com/patents/US6271358?dq=7,321,221
Patent US4401796 - Solid-phase synthesis of polynucleotides - Google Patents
Oligoribonucleotides and ribonucleases for cleaving RNA. US20030096287 *. Oct 25, 2002. May 22, 2003. Crooke Stanley T.. ... Oligoribonucleotides and ribonucleases for cleaving RNA. US20030096784 *. Oct 25, 2002. May 22, 2003. Crooke Stanley T.. ... Oligoribonucleotides and ribonucleases for cleaving RNA. US20030119777 *. Oct 25, 2002. Jun 26, 2003. Crooke Stanley T.. ... Oligoribonucleotides and ribonucleases for cleaving RNA. US7435390. Nov 13, 2001. Oct 14, 2008. Third Wave Technologies, Inc.. ...http://www.google.com/patents/US4401796
Patent US6683166 - Modified internucleoside linkages (ii) - Google Patents
Stawinski et al., "Studies on the t-butyldimethylsilyl group as 2'-O-protection in oligoribonucleotide synthesis via the H- ... Stawinski et al., "Studies on the t-butyldimethylsilyl group as 2′-O-protection in oligoribonucleotide synthesis via the H- ... al., "Association of 2'-5' Oligoribonucleotides" Nucl. Acids Res., 1992, 20, 1685-1690. ... al., "Association of 2′-5′ Oligoribonucleotides" Nucl. Acids Res., 1992, 20, 1685-1690. ...http://www.google.com/patents/US6683166?dq=%235,519,867
Features of Recent Codon Evolution: A Comparative Polymorphism-Fixation Study
S. S. Carroll, E. Chen, T. Viscount et al., "Cleavage of oligoribonucleotides by the 2. ′. ,. 5. ′. -oligoadenylate- dependent ...https://www.hindawi.com/journals/bmri/2010/202918/ref/
Catalytic effects of Murchison Material: Prebiotic Synthesis and Degradation of RNA Precursors | SpringerLink
Kierzek R (1992) Nonenzymatic hydrolysis of oligoribonucleotides. Nucleic Acids Res 20:5079-5084PubMedCrossRefGoogle Scholar ... Bibillo A, Figlerowicz M, Kierzek R (1999) The non-enzymatic hydrolysis of oligoribonucleotides. VI. The role of biogenic ... Lane BG, Butler GC (1959) The exceptional resistance of certain oligoribonucleotides to alkaline degradation. Biochim Biophys ... The reactivity of phosphodiester bonds within linear single-stranded oligoribonucleotides is strongly dependent on the base ...https://link.springer.com/article/10.1007%2Fs11084-011-9239-0
Patente US5780607 - Antisense oligomers - Google Patentes
Oligoribonucleotides and ribonucleases for cleaving RNA. US7696345. 4 Nov 2003. 13 Abr 2010. Isis Pharmaceuticals, Inc.. ... In contrast to existing art, antisense molecules of this invention are a new class of oligoribonucleotides comprising pyranosyl ...http://www.google.es/patents/US5780607?dq=flatulence
CYCLIC AMP PHOSPHODIESTERASE 4D7 ISOFORMS AND METHODS OF USE - Memory Pharmaceuticals Corporation
USA, 1990, 87, 7747-7751; Cotton et al., "2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate ... "2'O-Alkyl Oligoribonucleotides as Antisense Probes," Proc. Natl. Acad. Sci. ...http://www.freepatentsonline.com/y2005/0289660.html
US Patent # 5,698,687. Modified ribozymls - Patents.com
Digestion of oligoribonucleotides with RNase A Partial digestion of oligoribonucleotides with RNase A: The oligoribonucleotides ... Total degradation of oligoribonucleotides by RNAse A: The oligoribonucleotides S1 and S2 were digested with RNase A after 5'-. ... Preparation of oligoribonucleotides: The following oligoribonucleotides were prepared a.) by run off transcription (sequences ... Preparation of oligoribonucleotides Automated synthesis of oligoribonncleotides: Automated oligoribonucleotide synthesis was ...http://patents.com/us-5698687.html
RCSB PDB - Protein Feature View - Oligoribonuclease - Q83C93 (ORN COXBU)
3'-to-5' exoribonuclease specific for small oligoribonucleotides. UniProt Pathway Maps Maps: ...http://www.rcsb.org/pdb/protein/Q83C93
MicroRNA-338-3p suppresses cell proliferation and induces apoptosis of non-small-cell lung cancer by targeting sphingosine...
RNA oligoribonucleotides. The miR-338-3p mimics (GMR-miR MicroRNA-338-3p mimics) used in this study were synthesized by ...https://cancerci.biomedcentral.com/articles/10.1186/s12935-017-0415-9
KAKEN - Research Projects | CHEMICAL SYNTHESIS OF A NEW MATERIAL OF ANTISENSE NUCLEIC ACID '2'-PHOSPHORYLATED RNAS' -DIRECTED...
Phosphorylated Oligoribonucleotides Capable of Conversion to Oligoribonucleotides' Journal of Organic Chemistry. 58. 3204-3208 ... Publications] M.Sekine et al.: 'Chemical Synthesis of Branched Oligoribonucleotides and Their Related Compounds' Studies in ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05558090/
CN101686939B - Nucleic acid microparticles for pulmonary delivery - Google Patents
Oligoribonucleotides for cleaving RNA US5898221A (en) 1996-09-27. 1999-04-27. Sanyo Electric Company, Ltd.. Semiconductor ...https://patents.google.com/patent/CN101686939B/en
Preparation of Short Interfering RNA Containing the Modified Nucleosides 2‐Thiouridine, Pseudouridine, or Dihydrouridine -...
The synthesis of oligoribonucleotides. II. The use of silyl protecting groups in nucleoside and nucleotide chemistry. VIII. Can ... Modified oligoribonucleotides as site‐specific probes of RNA structure and function. Biopolymers 48:39‐55. ... Synthetic oligoribonucleotides carrying site‐specific modifications for RNA structure‐function analysis. Biochimie 76:1223‐1234 ... Synthesis of oligoribonucleotides containing 2‐thiouridine: Incorporation of 2‐thiouridine phosphoramidite without base ...http://www.currentprotocols.com/WileyCDA/CPUnit/refId-nc1602.html
EP2170403A2 - Compositions and methods for inhibiting expression of pro-apoptotic genes - Google Patents
Oligoribonucleotides for cleaving RNA JP2008501693A (en) * 2004-06-03. 2008-01-24. アイシス ファーマシューティカルズ、インク．. Duplex composition ... An siRNA of the invention is a duplex oligoribonucleotide in which the sense strand is derived from the mRNA sequence of the ... The terminal region of the oligoribonucleotide refers to bases 1-4 and/or 16-19 in the 19-mer oligomer sequence and to bases 1- ... Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases ...https://patents.google.com/patent/EP2170403A2
A ' mad race to the finish'
I used that enzyme to synthesize the oligoribonucleotides. I developed an array of what ultimately became 64 triplets. Most of ... By purification and enzymatic degradation techniques, we were able to develop very short oligoribonucleotide sequences and show ...http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=15865
The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes | SciVee
This includes oligodeoxy- as well as oligoribonucleotides. Mutations of selected lysine residues on the surface of the SUD-N ...http://www.scivee.tv/node/11155/