Van der Goes van Naters W (2013). "Inhibition among olfactory receptor neurons". Front Hum Neurosci. 7: 690. doi:10.3389/fnhum. ... model in which each olfactory receptor sends its signal to one neuron. The inhibition due to ephaptic coupling would help ... Neurons in the olfactory system are unmyelinated and densely packed and thus the often small effects of ephaptic coupling are ... A number of studies have shown how inhibition among neurons in the olfactory system work to fine-tune integration of signals in ...
Turetsky, Bruce I; Hahn, Chang-Gyu; Arnold, Steven E; Moberg, Paul J (February 2009). "Olfactory Receptor Neuron Dysfunction in ... may arise due to the local NMDA receptor blockage, which is also a pharmacological model of schizophrenia. These NMDA receptor ... Recent studies, reports on the new source of HFO in the olfactory bulb structures, which is surprisingly stronger than any ... Hunt, Mark J; Kasicki, Stefan (2013-07-17). "A systematic review of the effects of NMDA receptor antagonists on oscillatory ...
"Calcium Microdomains in the Chemosensory Cilia of Olfactory Receptor Neurons". Chemical Senses. 33 (8): S61. doi:10.1093/chemse ... Neuron Glia Biology. 6 (3): 183-191. doi:10.1017/s1740925x10000219. PMC 3136572. PMID 21205365. Thomsen, L. B. T. L. B.; ... effect of N-acetylcysteine against BDE-209-induced neurotoxicity in primary cultured neonatal rat hippocampal neurons in vitro ...
"A receptor guanylyl cyclase expressed specifically in olfactory sensory neurons". Proc Natl Acad Sci USA. 92 (8): 3571-3575. ... that is specifically expressed in a subpopulation of olfactory sensory neurons. This gene is a pseudogene in humans and most ... Young, JM (2007). "Degeneration of the olfactory guanylyl cyclase D gene during primate evolution". PLOS ONE. 2 (9): e884. ... Kuhn, M (2009). "Function and dysfunction of mammalian membrane guanylyl cyclase receptors: lessons from genetic mouse models ...
Olfactory nerve (cranial nerve 1) Smell. See also: olfactory receptor neurons Optic nerve (cranial nerve 2) Sight. See also: ... Olfactory sensory neurons project axons to the brain within the olfactory nerve, (cranial nerve #1). How olfactory information ... Sensory neuron, Sensory receptor, Proprioception, and Category:Sensory receptors), as a center for coordinating certain ... Many neurons connect to the brain on one end, with the other end connected to another neuron, with the outside (the brain) ...
Cabbage loopers possess olfactory receptor neurons on their antennae for detecting pheromones. The neurons are specifically ... Grant, A. J.; Riendeau, C. J.; OConnell, R. J. (1998-10-01). "Spatial organization of olfactory receptor neurons on the ... The base region of the antennae, where receptor neurons for this pheromone are located, has more sensory structures than the ... Temperature does not affect the pheromone-sensitive receptor neurons. The cabbage looper is a generalist insect that can reside ...
"Molecular profiling of activated olfactory neurons identifies odorant receptors for odors in vivo". Nature Neuroscience. 18 (10 ... Immunoprecipitation of RNA transcripts of murine olfactory cells have identified an enriched pool of odorant receptors ... that localize to the dorsal portion of the olfactory epithelium which can mediate fear behaviour. Rosen JB, Asok A, Chakraborty ... activated by TMT, including five receptors (Olfr20, Olfr30, Olfr57, Olfr376, Olfr491) ...
... an olfactory receptor) is found only in neurons. This finding of tissue-specific biologically-functional genes that could have ... Prieto-Godino LL, Rytz R, Bargeton B, Abuin L, Arguello JR, Peraro MD, Benton R (November 2016). "Olfactory receptor pseudo- ... However, in vivo the D. sechellia Ir75a locus produces a functional receptor, owing to translational read-through of the PTC. ... Read-through is detected only in neurons and depends on the nucleotide sequence downstream of the PTC. siRNAs. Some endogenous ...
Insect pheromone-binding protein Odorant Olfactory receptor Olfactory receptor neuron Vogt, R. G.; Prestwich, G. D.; Lerner, M ... delivering the odorant molecules to olfactory receptors in the cell membrane of sensory neurons. The olfactory receptors of ... soluble proteins secreted by auxiliary cells surrounding olfactory receptor neurons, including the nasal mucus of many ... "Odorant-binding-protein subfamilies associate with distinct classes of olfactory receptor neurons in insects". Journal of ...
"Olfactory receptor neurons detecting plant odours and male volatiles in Anomala cuprea beetles (Coleoptera: Scarabaeidae)". ...
CNG channels have important functions in signal transduction in retinal photoreceptors and olfactory receptor neurons. They are ... Almost all responses to odorants in olfactory sensory neurons (OSNs) are facilitated by CNG channels. When an odorant binds to ... CNG channels were also found in cone photoreceptors, chemo sensitive cilia of olfactory sensory neurons, and the pineal gland. ... CNGA2, previously called the olfactory α subunit, CNGA4, previously called the olfactory β subunit, and CnGB1b are involved in ...
They receive information from the axons of olfactory receptor neurons, forming synapses in neuropils called glomeruli. Axons of ... Mitral cells are neurons that are part of the olfactory system. They are located in the olfactory bulb in the mammalian central ... into a glomerulus receiving input from a population of olfactory sensory neurons expressing identical olfactory receptor ... Mitral cells receive input from at least four cell types: olfactory sensory neurons, periglomerular neurons, external tufted ...
Variable expression of Robo receptors on Drosophila olfactory neurons controls axonal organization in the olfactory lobes. In ... to the olfactory bulb, where they differentiate into olfactory neurons. The contribution of Robo signaling in this system is ... "The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons". Neuron. 43 (1): 69-79. ... Neuron. 22 (4): 649-52. doi:10.1016/s0896-6273(00)80723-0. PMID 10230784. Chétodal A (2010). "Slits and their receptors". In ...
... model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons". ... It may often be bound to calmodulin such as in the olfactory system to either enhance or repress cation channels. Other times ... Ca2+ ion can also determine the speed of adaptation in a neural system depending on the receptors and proteins that have varied ... In electrically excitable cells, such as skeletal and cardiac muscles and neurons, membrane depolarization leads to a Ca2+ ...
1 May 2003). "Attractiveness of Fruit and Flower Odorants Detected by Olfactory Receptor Neurons in the Fruit Chafer Pachnoda ... 1 September 2001). "Detection of fruit- and flower-emitted volatiles by olfactory receptor neurons in the polyphagous fruit ...
... model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons". ... Olfactory neurons utilize a feedback system from the levels of Ca2+ions to activate its adaptation to prolonged smells. Due to ... While large mechanosensory neurons such as type I/group Aß display adaptation, smaller type IV/group C nociceptive neurons do ... Kurahashi, Takashi; Menini, Anna (February 1997). "Mechanism of odorant adaptation in the olfactory receptor cell". Nature. 385 ...
These studies were instrumental to map the wiring of olfactory sensory neurons expressing different olfactory receptor genes to ... Bhalerao S, Sen A, Stocker RF, Rodrigues V (2003) Olfactory neurons expressing identified receptor genes project to subsets of ... "Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe ofDrosophila ... Stocker RF (2006) Olfactory coding: Connecting odorant receptor expression and behavior in the Drosophila larva (Dispatch). ...
Monoallelic expression was also found in mice olfactory receptor genes in olfactory sensory neurons. An upstream cis-acting DNA ... "one receptor-one neuron rule" (Serizawa et al, 2003), one olfactory receptor genes random activation and the expressed gene ... region controls an olfactory receptor gene clusters activation and resulted in monogenic expression of one olfactory receptor ... A vomeronasal receptor, V1R, exhibits allelic exclusion. When a V1R receptor gene is expressed, an odorant receptor gives ...
... localization and genomic organization of genes encoding guanylyl cyclase receptors expressed in olfactory sensory neurons and ...
He has made similarly important discoveries on olfactory transduction in the receptor neurons of the nasal olfactory epithelium ... Krautwurst D, Yau KW, Reed RR (1998). "Identification of ligands for olfactory receptors by functional expression of a receptor ... "Identification of ligands for olfactory receptors by functional expression of a receptor library", 534 citations 2002 " ... "Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons", 672 citations ...
Helena Bichão; Anna-Karin Borg-Karlson; Jorge Araújo; Hanna Mustaparta (2005). "Five types of olfactory receptor neurons in the ... Monoterpenes, sesquiterpenes, and aromatic compounds acted as odorants (attractors) on weevils receptor neurons. Male A. rubi ...
The new olfactory receptor neurons must project their axons through the CNS to an olfactory bulb in order to be functional. ... Olfactory ensheathing cells, however, cross the CNS-PNS boundary, because they guide olfactory receptor neurons from the PNS to ... Olfactory receptor neurons have an average lifespan of 6-8 weeks and therefore must be replaced by cells differentiated from ... receptor interacting protein (RIP), and glial fibrillary acidic protein (GFAP), which are markers for early neurons, ...
Each glomerulus collects information from a specific olfactory receptor neuron. The olfactory signal is then conducted to the ... a dime-sized region located in the nasal cavity that contains olfactory receptor neurons. There are 350 types of olfactory ... receptors, each sensitive to a narrow range of odorants. These neurons send signals to the glomeruli within the olfactory bulb ... An olfactory cue is a chemical signal received by the olfactory system that represents an incoming signal received through the ...
... of allelic exclusion are monoallelic expression of immunoglobulins in B and T cells and olfactory receptors in sensory neurons ... Chess A, Simon I, Cedar H, Axel R (September 1994). "Allelic inactivation regulates olfactory receptor gene expression". Cell. ... Neuron. 81 (1): 103-19. doi:10.1016/j.neuron.2013.10.051. PMC 3950970. PMID 24411735. Gimelbrant A, Hutchinson JN, Thompson BR ... Tanamachi DM, Hanke T, Takizawa H, Jamieson AM, Raulet DR (February 2001). "Expression of natural killer receptor alleles at ...
... the olfactory glomeruli function as sorts of way-stations for the information flowing from the olfactory receptor neurons to ... Neurons are necessary for all connections made in the brain, and thus can be thought of as the "wires" of the brain. As in ... For example, the neocortex and olfactory bulb both contain neuropil. White matter, which is mostly composed of myelinated axons ... There is also additional evidence that the neuropil may function in olfactory associative learning and memory. Research has ...
MS4A genes have been described to act as a specific kind of olfactory receptor in the necklace olfactory sensory neurons in ...
The olfactory receptor (OR) cells are neurons present in the olfactory epithelium, which is a small patch of tissue at the back ... There are millions of olfactory receptor neurons that act as sensory signaling cells. Each neuron has cilia in direct contact ... The olfactory bulb acts as a relay station connecting the nose to the olfactory cortex in the brain. Olfactory information is ... available to the olfactory receptors. A single odorant is usually recognized by many receptors. Different odorants are ...
... olfactory receptor neurons in the olfactory system: Olfaction involves the ability to detect chemicals in the gaseous state. In ... Within the olfactory system there are two anatomically distinct organs: the main olfactory epithelium (MOE) and the vomeronasal ... They are known as uniporous receptors. Some receptors are flexible, while others are rigid and do not bend with contact. They ... the nose and eventually reach the olfactory epithelium which houses the chemoreceptor cells known as olfactory sensory neurons ...
In contrast, a permanent loss of smell may be caused by death of olfactory receptor neurons in the nose or by brain injury in ... Another specific cause of permanent loss could be from damage to olfactory receptor neurons because of use of certain types of ... June 2020). "Innate immune signaling in the olfactory epithelium reduces odorant receptor levels: modeling transient smell loss ... doi:10.1016/j.neuron.2020.06.032. PMC 7328585. PMID 32640192. Iravani B, Arshamian A, Ravia A, Mishor E, Snitz K, Shushan S, et ...
Some examples in humans include the olfactory receptor neuron and Meissners corpuscle, which are critical for the sense of ... A mature neuron also undergoes shorter changes in membrane potential in response to synaptic currents. Neurons from a ferret ... Not all neurons in vertebrates are myelinated; for example, axons of the neurons comprising the autonomous nervous system are ... Typically, neurotransmitter molecules are released by the presynaptic neuron. These neurotransmitters then bind to receptors on ...