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*  Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity | Biochemical Journal
Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity. I Holen, P B Gordon, P O ... Okadaic acid was effectively antagonized by the general protein kinase inhibitors K-252a and KT-5926, the calmodulin antagonist ... The protein phosphatase inhibitor okadaic acid suppressed autophagy completely in isolated rat hepatocytes, as measured by the ... Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity ...
http://www.biochemj.org/content/284/3/633
*  Marine Drugs | Free Full-Text | Diarrhetic Shellfish Toxins and Other Lipophilic Toxins of Human Health Concern in Washington...
Okadaic acid, azaspiracid-1 (AZA-1) and azaspiracid-3 (AZA-3) were all below the levels of detection by liquid chromatography ... Here we show that the DSTs at concentrations above the guidance level of 16 μg okadaic acid (OA) + dinophysistoxins (DTXs)/100 ... Okadaic acid, azaspiracid-1 (AZA-1) and azaspiracid-3 (AZA-3) were all below the levels of detection by liquid chromatography ... Konoki, K.; Onoda, T.; Watanabe, R.; Cho, Y.; Kaga, S.; Suzuki, T.; Yotsu-Yamashita, M. In vitro acylation of okadaic acid in ...
http://mdpi.com/1660-3397/11/6/1815/htm
*  OKADAIC ACID for protein prep - Protein and Proteomics
OKADAIC ACID for protein prep - (Apr/08/2010 ). Has anyone used okadaic acid as a phosphatase inhibitor when prepping protein ... Has anyone used okadaic acid as a phosphatase inhibitor when prepping protein from cell or tissue homogenates (for use in ... 3. How worried should I be about working with okadaic acid? It has a rather daunting MSDS....Any specific recommendations on ... 3. How worried should I be about working with okadaic acid? It has a rather daunting MSDS....Any specific recommendations on ...
http://www.protocol-online.org/biology-forums-2/posts/14141.html
*  okadaic acid - Biology Forum | Biology-Online Dictionary, Blog & Forum
2) Okadaic acid question - This helps " Okadaic acid has no effect on Cdc2 phosphorylation because it is phosphorylated on a ... okadaic acid. Discussion of all aspects of cellular structure, physiology and communication. ... Tyrosine phosphatases are unaffected by okadaic acid. The decrease in Cdc2 phosphorylation is a consequence of the change in ... Note for question 2) Okadaic acid is an inhibitor of serine/threonine protein phosphatases. it is specific for serine/threonine ...
https://www.biology-online.org/biology-forum/viewtopic.php?t=731
*  Okadaic Acid Elisa Kit Moorestown - WorldBid B2B Market
Okadaic Acid Elisa Kit, Okadaic acid elisa kit RNA97008 Product Description REAGEN™ Okadaic acid elisa kit is a competitive ... Okadaic Acid Elisa Kit - USA. price: check with company for price. Okadaic Acid Elisa Kit Photos Catalog. ... Okadaic acid elisa kit. RNA97008. Product Description. REAGEN™ Okadaic acid elisa kit is a competitive enzyme immunoassay for ... Trans-1, 4-Cyclohexanedicarboxylic Acid Monomethyl Ester Product Name: Trans-1, 4-Cyclohexanedicarboxylic Acid Monomethyl Ester ...
http://www.worldbid.com/chemical/chemicals-reagents/okadaic-acid-elisa-kit-i203275.html
*  Okadaic acid - Wikipedia
However, the unique function of okadaic acid upon cells maintained biological interest in the molecule. Okadaic acid has been ... okadaic acid has shown promise in the world of medicine for numerous potential uses. During its initial discovery, okadaic acid ... was compared to and shown to be very chemically similar to okadaic acid several years later, and okadaic acid itself was ... several studies have been performed toward the synthesis of okadaic acid and its derivatives. 3 total syntheses of okadaic acid ...
https://en.wikipedia.org/wiki/Okadaic_acid
*  Marine Drugs | Free Full-Text | Okadaic Acid: A Tool to Study the Hippo Pathway
However other components of the Hippo pathway could also be targets of okadaic acid. In this review we first briefly summarize ... We explain how MST kinases are regulated by PP2A and how okadaic acid activates MST2. Thereafter we discuss which components of ... Okadaic acid has been frequently used to enhance the phosphorylation of MST1 and MST2 and to trigger the activation of the ... are activated in NIH3T3 cells exposed to okadaic acid. The Hippo pathway is a newly emerging signaling that functions as a ...
http://mdpi.com/1660-3397/11/3/896/xml
*  Marine Drugs | Free Full-Text | Self-Association of Okadaic Acid: Structural and Pharmacological Significance | HTML
Okadaic acid (OA) has been an invaluable pharmacological tool in the study of cellular signaling. The great affinity of this ... 2. Dimerization of Okadaic Acid Overview. 2.1. Complexation of Okadaic Acid. Norte et al. first reported in 1991 that the toxin ... Figure 2. Structure proposed for the okadaic acid-potassium complex [21]. Each okadaic acid monomer is shown in a different ... Figure 2. Structure proposed for the okadaic acid-potassium complex [21]. Each okadaic acid monomer is shown in a different ...
http://www.mdpi.com/1660-3397/11/6/1866/htm
*  Mimicking mitotic Golgi disassembly using okadaic acid | Journal of Cell Science
Mimicking mitotic Golgi disassembly using okadaic acid Message Subject (Your Name) has sent you a message from Journal of Cell ...
http://jcs.biologists.org/content/103/4/875
*  Okadaic acid induced neurotoxicity: An emerging tool to study Alzheimer's disease pathology
... ... Okadaic acid (OKA) is one of the main polyether toxins produced by marine microalgae which causes diarrhetic shellfish ...
https://insights.ovid.com/neutox/201307001/01720099-201307001-00020
*  The effect of okadaic acid on non-adrenergic non-cholinergic contraction in guinea-pig isolated bronchus.
... vs okadaic acid, 33 +/- 8.9%; 30 Hz, control, 50 +/- 7.6% vs okadaic acid, 42 +/- 14%; P , 0.05, n = 4). 4. Okadaic acid (0.3 ... okadaic acid, 9.0 +/- 0.5, vs DMSO, 9.2 +/- 0.4; P , 0.05 n = 6), substance P (okadaic acid, 7.6 +/- 0.3 vs DMSO, 8.2 +/- 0.2; ... okadaic acid, 6.4 +/- 0.2 vs DMSO, 6.4 +/- 0.3; P , 0.05 n = 4). 5. Okadaic acid (0.01-1 microM) did not appear to reverse ... vs okadaic acid, 18 +/- 7.7%; 3 Hz, control, 26 +/- 6.9% vs okadaic acid, 27 +/- 9.1%; 10 Hz, control, 36 +/- 7.6% ...
http://www.biomedsearch.com/nih/effect-okadaic-acid-non-adrenergic/9154325.html
*  Effects of the Phosphatase Inhibitors, Okadaic Acid, ATPγS, and Calyculin A on the Dividing Sand Dollar egg
The effects of the phosphatase inhibitors, okadaic acid (OA), adenosine 5'-O-(3-thiotriphosphate) (ATPγS), and calyculin A (CL- ...
https://www.jstage.jst.go.jp/article/csf/27/3/27_3_127/_article
*  Marine Drugs | Free Full-Text | Comparative Analysis of the Cytotoxic Effects of Okadaic Acid-Group Toxins on Human Intestinal...
... okadaic acid (OA) and dinophysistoxin 1 and 2 (DTX-1 and -2) are protein phosphatase PP2A and PP1 inhibitors involved in ... okadaic acid; dinophysistoxins; apoptosis; γ-H2AX; inflammation; proliferation high content analysis; okadaic acid; ... Comparative Analysis of the Cytotoxic Effects of Okadaic Acid-Group Toxins on Human Intestinal Cell Lines. Pierre-Jean Ferron, ... The phycotoxin, okadaic acid (OA) and dinophysistoxin 1 and 2 (DTX-1 and -2) are protein phosphatase PP2A and PP1 inhibitors ...
https://www.mdpi.com/1660-3397/12/8/4616
*  Toxins | Free Full-Text | Evaluation of the Impact of Mild Steaming and Heat Treatment on the Concentration of Okadaic Acid,...
7-O-palmitoyl okadaic ester and 7-O-palmytoleyl okadaic ester). The results show that the loss of water due to steaming was ... Keywords: steaming; dinophysistoxin; okadaic acid; mass spectrometry steaming; dinophysistoxin; okadaic acid; mass spectrometry ... Evaluation of the Impact of Mild Steaming and Heat Treatment on the Concentration of Okadaic Acid, Dinophysistoxin-2 and ... Evaluation of the Impact of Mild Steaming and Heat Treatment on the Concentration of Okadaic Acid, Dinophysistoxin-2 and ...
https://www.mdpi.com/2072-6651/8/6/175/xml
*  Toxins | Free Full-Text | Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic...
A phosphatase inhibition assay for detection of okadaic acid (OA) toxins in shellfish, OkaTest, was single laboratory validated ... Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic Acid Toxins. Henry G. F. ... "Single Laboratory Validation of A Ready-to-Use Phosphatase Inhibition Assay for Detection of Okadaic Acid Toxins." Toxins 4, no ... A phosphatase inhibition assay for detection of okadaic acid (OA) toxins in shellfish, OkaTest, was single laboratory validated ...
http://www.mdpi.com/2072-6651/4/5/339/xml
*  Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of...
Okadaic Acid, a Bioactive Fatty Acid from Halichondria okadai, Stimulates Lipolysis in Rat Adipocytes: The Pivotal Role of ... P. Cohen, C. F. B. Holmes, and Y. Tsukitani, "Okadaic acid: a new probe for the study of cellular regulation," Trends in ... R. Nuydens, M. De Jong, G. Van Den Kieboom et al., "Okadaic acid-induced apoptosis in neuronal cells: evidence for an abortive ... T. A. J. Haystead, A. T. R. Sim, D. Carling et al., "Effects of the tumour promoter okadaic acid on intracellular protein ...
https://www.hindawi.com/journals/ecam/2013/545739/ref/
*  Toxins | Free Full-Text | PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in...
Okadaic acid and its analogs (OAs) responsible for diarrhetic shellfish poisoning (DSP) strongly inhibit protein phosphatase 2A ... Okadaic acid and its analogs (OAs) responsible for diarrhetic shellfish poisoning (DSP) strongly inhibit protein phosphatase 2A ... PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish. Tsuyoshi ... "PP2A Inhibition Assay Using Recombinant Enzyme for Rapid Detection of Okadaic Acid and Its Analogs in Shellfish." Toxins 2, no ...
http://www.mdpi.com/2072-6651/2/1/195
*  Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells | Bastyr...
The microbial toxin okadaic acid (OA) specifically inhibits PPP-type ser/thr protein phosphatases. OA is an established tumor ... Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells. #main- ... The microbial toxin okadaic acid (OA) specifically inhibits PPP-type ser/thr protein phosphatases. OA is an established tumor ... Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells ...
https://bastyr.edu/research/studies/inhibition-pp2a-not-pp5-mediates-p53-activation-low-levels-okadaic-acid-rat-liver
*  Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship | Biochemical...
The effect of structural modifications of okadaic acid (OA), a polyether C38 fatty acid, was studied on its inhibitory activity ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship. A Takai, M ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship ... Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship ...
http://www.biochemj.org/content/284/2/539
*  Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem CAS 155751-72-7 | 459618
... is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and ... More,, Okadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent ... Okadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor ... Okadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor ...
http://www.emdmillipore.com/PR/en/product/Okadaic-Acid-Potassium-Salt-CAS-155751-72-7-Calbiochem,EMD_BIO-459618
*  Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem CAS 155716-06-6 | 459616
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A. Find MSDS or SDS, a COA, data sheets and more ... Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem. 459616 , Okadaic Acid, Ammonium Salt - CAS 155716-06-6 - Calbiochem ... Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.. More,, Water-soluble analog of Okadaic Acid. ... Okadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem. Show Pricing & Availability ...
http://www.emdmillipore.com/US/en/product/Okadaic-Acid-Ammonium-Salt-CAS-155716-06-6-Calbiochem,EMD_BIO-459616
*  Cdc45/Mcm2-7/GINS complex down-regulation mediates S phase arrest in okadaic acid-induced cell damage
... ... Okadaic acid (OA) is one of the most common and widespread marine toxins and causes acute gastrointestinal symptoms known as ...
https://insights.ovid.com/toxic/201809150/00007824-201809150-00003
*  Cytoprotection by Melatonin, Precursors and Metabolites in an In Vitro Model of Neurotoxicity Induced by Okadaic Acid | Bentham...
The effects of okadaic acid were evaluated as changes in the quantity of lipid peroxidation products, reduced glutathione (GSH ... The effects of okadaic acid were evaluated as changes in the quantity of lipid peroxidation products, reduced glutathione (GSH ... Cytoprotection by Melatonin, Precursors and Metabolites in an In Vitro Model of Neurotoxicity Induced by Okadaic Acid. Author(s ... Title: Cytoprotection by Melatonin, Precursors and Metabolites in an In Vitro Model of Neurotoxicity Induced by Okadaic Acid ...
http://www.eurekaselect.com/79165
*  Gentaur Molecular :LCLabs \ Okadaic Acid, Free Acid \ O-2220
Okadaic Acid, Free Acid \ O-2220 for more molecular products just contact us ... We have also other products like : Okadaic Acid, Free Acid. Related products : Okadaic Acid, Free Acid ... amino acid conjugation of benzoic acid. WP1307: Fatty Acid Beta Oxidation. WP1311: Folic Acid Network. WP133: Fatty Acid Omega ... amino acid conjugation of benzoic acid. WP1020: Fatty Acid Biosynthesis. WP105: Fatty Acid Beta Oxidation 2. WP1061: Fatty Acid ...
http://www.antibody-antibodies.com/product236431-LCLabs-Okadaic_Acid,_Free_Acid.html
*  Effects of cooking and heat treatment on concentration and tissue distribution of okadaic acid and dinophysistoxin-2 in mussels...
In parallel, the same studies were carried out for okadaic acid and dinophysistoxin-2 also naturally present in the samples ... More so than for azaspiracids, increased distribution of okadaic acid and dinophysistoxin-2 from the digestive glands to the ... Effects of cooking and heat treatment on concentration and tissue distribution of okadaic acid and dinophysistoxin-2 in mussels ... okadaic acid and dinophysistoxin-2 in mussels (Mytilus edulis) was investigated. A prior study looking at the influence of ...
https://oar.marine.ie/handle/10793/420