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TNBP and Octoxynol used in the manufacturing process for viral inactivation may be present in the final product at levels not ... No evidence of toxicity was observed for TNBP + Octoxynol in sub-acute toxicity studies.3 ... octoxynol for 1-1.5 hours at +30°C (86°F)] to inactivate enveloped viruses. The S/D reagents are removed by sequential oil and ... Evaluation of the cytotoxicity and genotoxicity of the spermicides nonoxynol-9 and octoxynol-9. Toxicol.Lett. 1986;31:65-73 ...