Octamer transcription factor - Wikipedia
Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA- ... Octamer+transcription+factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ... Zhao, FQ (1 June 2013). "Octamer-binding transcription factors: genomics and functions". Frontiers in Bioscience (Landmark ... "Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors ...
Isotypes - Octamer-binding transcription factor 4
Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4. Oct-4 is a homeodomain transcription factor of the POU family.\ ... Inhibition of neural stem cell aging through the transient induction of reprogramming factors. by Alyssa ...
rna vaccine - Octamer-binding transcription factor 4
Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4. Oct-4 is a homeodomain transcription factor of the POU family.\ ... Inhibition of neural stem cell aging through the transient induction of reprogramming factors ...
Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors...
Octamer Transcription Factor-2 * Proto-Oncogene Proteins / biosynthesis * Proto-Oncogene Proteins / genetics* ... Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors ... and PU.1 transcription factors and the lack of IgV(H) gene crippling mutations. ...
Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding...
Methods: We used electrophoretic mobility shift assays to examine the effect of the 3 SNPs on transcription factor binding in 3 ... mobility shift assays show that rs1046295 modulates allele-specific binding by the octamer-binding transcription factor 1 (Oct- ... Conclusion: These results suggest a mechanism by which rs1046295 may act as a regulatory variant modulating transcription at ... modulated by octamer-binding transcription factor 1 (Oct-1) Holt RJ., Zhang Y., Binia A., Dixon AL., Vandiedonck C., Cookson WO ...
Cancers | Free Full-Text | Transcription Factor RBPJL Is Able to Repress Notch Target Gene Expression but Is Non-Responsive to...
The transcription factor RBPJ forms a coactivator complex in the presence of a Notch signal, whereas it represses Notch target ... Both RBPJL and RBPJ bind to the same conserved octamer motif. Single-molecule experiments reveal that the binding times of both ... The ubiquitously expressed transcription factor RBPJ is the central switch that can actively repress transcription in the ... Transcription Factor RBPJL Is Able to Repress Notch Target Gene Expression but Is Non-Responsive to Notch Activation by Leiling ...
SCOPe 2.08: Domain d1e3oc2: 1e3o C:1-75
The BOB.1 / OBF.1 co-activator is essential for octamer-dependent transcription in B cells
... is a B cell-specific co-activator of the Oct1 and Oct2 transcription factors. It is involved in mediating the transcriptional ... OBF.1 for octamer-dependent transcription. We show that promoters exclusively dependent on functional octamer motifs are ... The BOB.1 / OBF.1 co-activator is essential for octamer-dependent transcription in B cells Eur J Immunol. 2000 Feb;30(2):458-69 ... is a B cell-specific co-activator of the Oct1 and Oct2 transcription factors. It is involved in mediating the transcriptional ...
Genome-wide analysis of estrogen receptor binding sites | Nature Genetics
... the identification of cis-regulatory sites in previously unexplored regions of the genome and the cooperating transcription ... Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the ... Figure 4: Identification of enriched motifs within the estrogen receptor binding sites and validation of transcription factor ... Figure 5: Involvement of cooperating transcription factors at estrogen receptor binding sites.. ...
Journal of Investigative Dermatology
... protein S and octamer transcription factor-3). Our results show a significant increase of Cw*0602 in psoriasis patients (odds ... The allele octamer transcription factor-3B (etiologic fraction = 0.62) was found to be more strongly associated to psoriasis ... or corneodesmosin gene and octamer transcription factor-3 genes (which are telomeric to HLA-C), might play a part in disease ... and the increase of octamer transcription factor-3 B allele is independent of the linkage disequilibrium with Cw*0602 as this ...
Medical Science Monitor | Elastic Net-Based Identification of a Multigene Combination Predicting the Survival of Patients with...
CONCLUSIONS:We developed a multigene combination which could be treated as an independent prognostic factor in cervical cancer ... The Octamer-Binding Transcription Factor 4 (OCT4) Pseudogene, POU Domain Class 5 Transcription Factor 1B (POU5F1B), is ... Effects of Intrinsic and Extrinsic Factors on the Level of Hope and Psychological Health Status of Patients with Cervical ... Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ... DOI :10.12659/ ...
GLUCURONIDATION AND THE UDP-GLUCURONOSYLTRANSFERASES IN HEALTH AND DISEASE | Drug Metabolism & Disposition
Octamer transcription factor-1 is another member of the homeodomain group of transcription factors. It acts as a positive ... In this respect, it is interesting to note that the ubiquitous transcription factor, octamer transcription factor-1, acts ... Ishii Y, Hansen AJ, and Mackenzie PI (2000) Octamer transcription factor-1 enhances hepatic nuclear factor-1 alpha-mediated ... Studies on rodent UGT genes have demonstrated that the transcription factors hepatocyte nuclear factor 1 (HNF1) and CAAT- ...
Cancers | Free Full-Text | Inhibiting ALK2/ALK3 Signaling to Differentiate and Chemo-Sensitize Medulloblastoma
The octamer-binding transcription factor 4 (OCT4), an important regulator of embryonic pluripotency, enhanced CSC maintenance ... Several transcription factors involved in embryonic stem-cell maintenance such as the octamer-binding transcription factor 4 ( ... The octamer-binding transcription factor 4 (OCT4), an important regulator of embryonic pluripotency, enhanced CSC maintenance ... Among these factors, OCT4 has emerged as the master transcription factor governing self-renewal and pluripotency in stem cells ...
CC10 Antibody Staining Protocol for Immunohistochemistry
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JCI - RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models
... including octamer-binding transcription factor 4 (Oct4, renal stem/progenitor cells), paired box gene 2 (Pax2, intermediate ... such as placental growth factor (PLGF) and soluble fms-like tyrosine kinase-1 (sFLT-1), since both factors are altered in ... siRNA against hAgt alters proangiogenic and antiangiogenic factors. (A) Serum PLGF concentrations were increased in hAgt- ... Angiogenic factors in diagnosis, management, and research in preeclampsia. Hypertension. 2014;63(2):198-202.. View this article ...
Eternal youth? Chemical cocktails prove effective in cell age reversal
Octamer-binding transcription factor 4 (OCT-4), sex-determining region Y-box 2 (SOX2), and Kruppel-like factor 4 (KLF-4) ( ... The authors of the present study previously demonstrated that ectopically induced transcription factors, ... Growth Factor, Hypoxia, Imaging, Induced Pluripotent Stem Cells, Inflammation, Interferon, Kinase, Lentivirus, OCT, ... Phosphorylation, Pluripotency, Ribonucleic Acid, RNA, Small Molecules, Somatic Cells, Stem Cells, Transcription, Transcription ...
Blog - Governing the Fate of Stem Cells With Transcription Factors
Transcription factors have crucial roles in stem cell biology and differentiation. Research in these fields has broad ... Oct4 (Octamer binding transcription factor 4) is an important marker of the undifferentiated state and central regulator of ... Transcription factors are proteins that regulate the transcription of genes, or the production of mRNA from DNA. Their unique ... Once the transcription factor binds to an enhancer region, this can cause stimulation or repression of gene transcription. ...
OAC1 | STEMCELL Technologies
Octamer-binding transcription factor 4 (Oct4) has been shown to be an essential regulator of embryonic stem cell (ESC) ... is a transcription factor that is critically involved in the self-renewal of pluripotent stem cells, and its expression is ... from mouse somatic cells by transduction of four defined transcription factors. Here, we demonstrate the generation of iPS ... OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and Tet1, a gene known to be involved in DNA demethylation. View ...
Mouse Pluripotent Stem Cell Transcription Factor Analysis Kit
Okamoto K, Okazawa H, Okuda A, Sakai M, Muramatsu M, Hamada H. A novel octamer binding transcription factor is differentially ... The entire BD Mouse Pluripotent Stem Cell Transcription Factor Analysis Kit must be stored in the dark at 2° to 8°C. Do not ... mouse ESC from the ES-E14TG2a cell line stained using the BD Stemflow Mouse Pluripotent Stem Cell Transcription Factor Analysis ... mouse ESC from the ES-E14TG2a cell line stained using the BD Stemflow Mouse Pluripotent Stem Cell Transcription Factor Analysis ...
Role of Alix in miRNA packaging during extracellular vesicle biogenesis
... octamer-binding transcription factor 3/4 (Oct 3/4), Sox2, Musashi1, nestin, nanog and pax2 (20,22). The expression of albumin ... In particular, the transfer of transcription factors, mRNAs and non-coding RNAs has been shown to induce epigenetic ... cDNA obtained by reverse transcription of 200 ng of RNA using the miScript Reverse Transcription kit was then subjected to RT- ... Following reverse transcription of the RNA (200 ng), the cDNA was subjected to RT-qPCR to quantify miRNAs as described above. ...
Human GABPa(GA Binding Protein Transcription Factor Alpha) ELISA Kit - Theragen Bio
Human Octamer Binding Transcription Factor 4 (OCT4) ELISA Kit. SEA424Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate ... Human GABPa(GA Binding Protein Transcription Factor Alpha) ELISA Kit. Human GA Binding Protein Transcription Factor Alpha ( ... Human OCT4(Octamer Binding Transcription Factor 4) ELISA Kit. *Human OCTN1(Organic Cation/Ergothioneine Transporter) ELISA Kit ... Description: A sandwich ELISA kit for detection of Octamer Binding Transcription Factor 4 from Human in samples from blood, ...
Transcriptiojn Factor Binding Assay - PeanutDB Plant Genomic sequence Database
Description: A sandwich ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 4 in samples from blood ... Description: A sandwich ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 4 in samples from blood ... Description: A sandwich ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 4 in samples from blood ... Description: A competitive ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 1 in samples from ...
Cigarette smoking promotes keratinocyte malignancy via generation of cancer stem-like cells<...
... which are rich in octamer-binding transcription factor (OCT)-4, inhibitor of differentiation 1 (ID1), nuclear factor (NF)-κB, ... which are rich in octamer-binding transcription factor (OCT)-4, inhibitor of differentiation 1 (ID1), nuclear factor (NF)-κB, ... which are rich in octamer-binding transcription factor (OCT)-4, inhibitor of differentiation 1 (ID1), nuclear factor (NF)-κB, ... which are rich in octamer-binding transcription factor (OCT)-4, inhibitor of differentiation 1 (ID1), nuclear factor (NF)-κB, ...
SMART: POU domain annotation
... is derived from the names of three mammalian transcription factors, the pituitary-specific Pit-1, the octamer-binding proteins ... Pituitary-specific positive transcription factor 1 (P28069) (SMART). OMIM:173110: Pituitary hormone deficiency, combined. ... TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE ... POU proteins are eukaryotic transcription factors containing a bipartite DNA binding domain referred to as the POU domain. The ...
Investigating the role of the DNA entry-exit site of the nucleosome in transcription termination - D-Scholarship@Pitt
Transcription is controlled by factors that remove or modify nucleosomes, allowing RNA polymerase II to contact otherwise ... Chromatin consists of repeating nucleosomes, which contain approximately 147 base pairs of DNA surrounding an octamer of ... function of the DNA entry-exit site in transcription termination depends on interaction with other chromatin-related factors. ... In eukaryotes, DNA is packaged as chromatin, which acts as a barrier between the transcription machinery and genomic material. ...
Regulation of Chromatin Accessibility in Cellular Reprogramming: Pioneer Transcription Factors, Epigenetics and Nuclear Actin
In eukaryotes, genomic DNA is wound around an octamer of the four core histones to form nucleosomes, which creates a higher- ... This subset of transcription factors, known as pioneer transcription factors (PTFs), possess the ability to engage closed ... Above: Pioneer transcription factors bind closed chromatin to enhance accessibility for other transcription factors and ... identified the transcription factor LEAFY as a PTF with the ability to bind nucleosome-occupied[6] DNA, displace H1 linker ...
Characterization of an acetylcholine receptor α3 gene promoter and its activation by the POU domain factor SCIP/Tst-1<...
Octamer Transcription Factor-6 Medicine & Life Sciences 43% * Sympathetic Ganglia Medicine & Life Sciences 26% ... that the POU domain transcription factor, SCIP/Tst-1, specifically activates α3 in a neural context. Other POU domain factors ... that the POU domain transcription factor, SCIP/Tst-1, specifically activates α3 in a neural context. Other POU domain factors ... that the POU domain transcription factor, SCIP/Tst-1, specifically activates α3 in a neural context. Other POU domain factors ...
Xenopus laevis octamer-binding proteins - WRAP: Warwick Research Archive Portal
The ubiquitous human octamer-binding transcription factor, Oct-1, is believed to regulate the expression of a number of ... The octamer motif may be required for the expression of both H2B and H2A genes. The degenerate octamer motif contained in this ... It is possible that histone gene transcription factors are stored for the same purpose. ... Oct-1, and a second, previously unidentified octamer-binding protein which has been termed Oct-R, for octamer-related. Oct-1 ...