Recombinant Human Occludin protein (ab114190) | Abcam
Buy our Recombinant Human Occludin protein. Ab114190 is a protein fragment produced in Wheat germ and has been validated in WB ...http://www.abcam.com/recombinant-human-occludin-protein-ab114190.html
Anti-Rat Occludin Antibody | Rat Occludin Antibody | Occludin Antibody
Anti-Rat Occludin (1A8) Mouse IgM MoAb. Occludin is an integral membrane protein, encoded by the OCLN gene, that is located at ... When occludin is expressed in cells that lack tight junctions, it is able to induce cell adhesion. Mutations in the OCLN gene ... Occludin is also known as BLCPMG. It is known to interact with several cytoplasmic proteins via its C terminus, while its ... This product is an affinity-purified IgG antibody that recognizes rat occludin protein. The antibody was raised in mouse using ...http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Cell_Adhesion_and_Extracellular_Matrix/Occludin?sitex=10020:22372:US&PEBCL1=zLSjmxeOHFQ4fzng3rPLKxEY2J&PEBCL1_pses=ZG3CA3A96ED9130025CEC007C52BEC16721BCE94DD4079701833DC95A17BFDCB947B22F5DDED73E29F747C4331E08306E4C8890DB2E388CF13
Transcriptional control of occludin expression in vascular endothelia: regulation by Sp3 and YY1 - Open Research Online
... which differentially interact with the occludin promoter to induce expression of occludin in brain endothelium and repression ... Transcriptional control of occludin expression in vascular endothelia: regulation by Sp3 and YY1.. Biochimica et Biophysica ... Endothelium; occludin; tight junctions; differentiation; YY1; Sp3; transcription factors;. Academic Unit/School:. Faculty of ... Expression of occludin in brain endothelium corresponded with binding of Sp3 to a minimal promoter segment close to the ...http://oro.open.ac.uk/12977/
P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein...
P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein ... creating the occludin/ZO-1/FAK/P-glycoprotein regulatory complex. Interestingly, a knockdown of P-glycoprotein by RNAi was ... This effect was mediated by changes in the protein phosphorylation status of occludin via the action of FAK, thereby affecting ... an ATP-dependent efflux drug transporter and an integrated component of the occludin/zonula occludens 1 (ZO-1) adhesion complex ...http://www.popcouncil.org/research/p-glycoprotein-regulates-blood-testis-barrier-dynamics-via-its-effects-on-t
Expression and regulation of tight junction protein Occludin in nasal polyps]. - Semantic Scholar
The regulatory effects of proinflammatory cytokines (IFN-γ, IL-13, IL-17, TGF-β, TGF-α) on the expression of Occludin in ... The mean optical density of Claudin-1, Occludin and ZO-1 were 0.187 ± 0.076,0.172 ± 0.109 and 0.098 ± 0.035 respectively in the ... METHODS The expression of Claudin-1, Occludin and ZO-1 in nasal polyps (n = 20) and healthy uncinate mucosa (n = 15) were ... RESULTS The immunohistochemical results showed that Claudin-1, Occludin and ZO-1 were detected both in the nasal polyp group ...https://www.semanticscholar.org/paper/Expression-and-regulation-of-tight-junction-prote-Chen-Guo/ca33633b1facac1950a14a3174b98809b4430324
Tight junction regulation through vesicle trafficking: bringing cells together | Biochemical Society Transactions
... in particular trafficking of the TJ protein occludin. We examine how endocytosis and endosomal recycling modulate occludin ...http://www.biochemsoctrans.org/content/42/1/195
Amyloid-β Contributes to Blood-Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With...
... occludin, and ZO-1 expression in human brain microvessels.23 We did not observe reduced occludin and ZO-1 expression but found ... ZO-1, occludin, claudin-1, and claudin-5 antibodies were from Invitrogen (Carlsbad, CA). MMP-2, MMP-9, β-actin antibodies, and ... Amyloid-beta-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK ... Expression of the TJ proteins ZO-1 and occludin remained unchanged. C, Zymogram showing increased MMP-9 activity in isolated ...http://stroke.ahajournals.org/content/43/2/514
Quantitative MRI reveals the elderly ischemic brain is susceptible to increased early blood-brain barrier permeability...
... to increased early blood-brain barrier permeability following tissue plasminogen activator related to claudin 5 and occludin ... alteplase; claudin 5; gadolinium pentetate; occludin; age distribution; aged; aging; animal experiment; animal model; article; ... mediated through the acute disassembly of claudin 5 and occludin. Increased T 2 values over the first hour of postreperfusion ... Both tPA and age independently increased claudin 5 and occludin phosphorylation during ischemia. Early BBB permeability ...http://nparc.nrc-cnrc.gc.ca/eng/view/object/?id=ae12c4a7-5885-474d-9f42-8acdfa74a406
Barriers and Channels Formed by Tight Junction Proteins I, Volume 1257 | Proteins & Macromolecules | Cell & Molecular Biology |...
... occludin, Marvel-D2, and tricellulin). Barriers and Channels Formed by Tight Junction Proteins I showcases work in this area ...https://www.wiley.com/en-us/Barriers+and+Channels+Formed+by+Tight+Junction+Proteins+I%2C+Volume+1257-p-9781573318730
Occludin (IPR002958) | InterPro | EMBL-EBI
Occludin was the first molecular component of the tight junction to be identified. These are specialised membrane domains that ... Occludin and claudins in tight-junction strands: leading or supporting players?. Trends Cell Biol. 9 268-73 1999 ... Occludin is an ~65 kDa type II integral membrane protein, which has been shown to have four transmembrane (TM) domains, two ... since occludin-deficient cells are still able to form tight junctions when cultured in vitro [PMID: 10370242]. ...http://www.ebi.ac.uk/interpro/entry/IPR002958
Occludin homology domain (IPR010844) | InterPro | EMBL-EBI
Occludin is an integral membrane protein that localises to tight junctions [PMID: 8276896], while ELL is an elongation factor ... Occludin: a novel integral membrane protein localizing at tight junctions.. J. Cell Biol. 123 1777-88 1993 ... Occludin: a novel integral membrane protein localizing at tight junctions.. J. Cell Biol. 123 1777-88 1993 ... This represents a conserved region approximately 100 residues long within eukaryotic occludin proteins and the RNA polymerase ...https://www.ebi.ac.uk/interpro/entry/IPR010844
Produktübersicht anti-Occludin Antikörper
Ausgesuchte Qualitäts-Hersteller für Occludin Antikörper. Hier bestellen. ... Monoklonale und polyklonale Occludin Antikörper für viele Methoden. ... occludin b , tight-junction protein , thiopurine methyltransferase , occludin , occludin-like , tight junction protein occludin ... Human Occludin (OCLN) Interaktionspartner * integration of claudin-2 (zeige CLDN2 Antikörper), occludin and ZO-1 (zeige TJP1 ...http://www.antikoerper-online.de/cell-cell-junction-organization-pathway-74/occludin-antibody-11504/
Occludin antibody | acris-antibodies.com
Background of Occludin antibody. Kit Component:. - KN311431G1, Ocln gRNA vector 1 in pCas-Guide vector. - KN311431G2, Ocln gRNA ... Recombinant protein of human occludin (OCLN). Human. > 80 % Preparation: Recombint protein was captured through anti-DDK ... Human Lung stained with Anti-Occludin antibody Cat.-No AP15690PU. *AP15690PU-S ...https://www.acris-antibodies.com/target/occludin-antibody.htm?target=Occludin
Occludin antibody | acris-antibodies.com
Background of Occludin antibody. Kit Component:. - KN311431G1, Ocln gRNA vector 1 in pCas-Guide vector. - KN311431G2, Ocln gRNA ... Human Lung stained with Anti-Occludin antibody Cat.-No AP15690PU. *AP15690PU-S ...https://www.acris-antibodies.com/target/occludin-antibody.htm?ab_host=Guinea+Pig
Occludin - Wikipedia
Occludin is a protein that in humans is encoded by the OCLN gene. Occludin is a 65-kDa (522-amino acid polypeptide -human) ... "Entrez Gene: OCLN occludin". Furuse M, Hirase T, Itoh M, Nagafuchi A, Yonemura S, Tsukita S, Tsukita S (1993). "Occludin: a ... Occludin also plays an important role in the apoptosis. The C-terminus of occludin is important in receiving and transmitting ... Occludin plays a critical role in maintaining the barrier properties of a tight junction. Thus, mutation or absence of occludin ...https://en.wikipedia.org/wiki/Occludin
anti-Occludin Antikörper (AA 446-474, C-Term) | Produkt Nr. ABIN657822
Jetzt diesen anti-Occludin Antikörper bestellen. , Produkt ABIN657822 ... Kaninchen Polyklonal Occludin Antikörper AA 446-474, C-Term für WB. Publiziert in 2 Pubmed Referenzen. ... Target Details Occludin Referenzen Bilder Handhabung Anwendungsinformationen zurück nach oben Target Details Occludin Anzeigen ... anti-Occludin Antikörper (OCLN) (AA 446-474) Occludin Antikörper (OCLN) (AA 446-474). Details for Product anti-OCLN Antibody No ...http://www.antikoerper-online.de/antibody/657822/anti-Occludin+OCLN+AA+446-474,+C-Term+antibody/
Occludin Antibody (66378-1-Ig) | | Proteintech
Proteintech mouse monoclonal Occludin antibody manufactured and validated in-house in WB, and IHC to detect human, mouse, rat ... WB result of Occludin antibody (66378-1-Ig; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-Occludin ... WB result of Occludin antibody (66378-1-Ig; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-Occludin ... Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can ...https://www.ptglab.com/Products/Occludin-Antibody-66378-1-Ig.htm
Occludin Antibody 27260-1-AP | Proteintech
Occludin Antibody 27260-1-AP has been identified with IHC, IP, WB, ELISA. 27260-1-AP detected 59 kDa band in HUVEC cells with 1 ... Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can ... Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane ... mouse kidney tissue were subjected to SDS PAGE followed by western blot with 27260-1-AP( Occludin Antibody) at dilution of 1: ...https://www.ptglab.com/Products/Occludin-Antibody-27260-1-AP.htm
Metformin promoted ZO-1, occludin and claudin-5 rearran | Open-i
A) Occludin, ZO-1 and claudin-5 expression in sham ... occludin and claudin-5 rearrangement and lessened IgG and Evans ... Fig4: Metformin promoted ZO-1, occludin and claudin-5 rearrangement and lessened IgG and Evans blue extravasation. (A) Occludin ... Fig4: Metformin promoted ZO-1, occludin and claudin-5 rearrangement and lessened IgG and Evans blue extravasation. (A) Occludin ... Result indicated that occludin and ZO-1 were continuously located on the margin of ECs in sham group, claudin-5 was ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4201919_12974_2014_177_Fig4_HTML&req=4
Addgene: Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1).
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). Runkle EA, Rice SJ, Qi J, Masser D, Antonetti DA ...http://www.addgene.org/browse/article/6917/
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo | JCB
Jejunal epithelia were isolated from wild-type and EGFP-occludin transgenic mice. Occludin, EGFP-occludin, and actin content ... Wild-type tissue was labeled for occludin (top; green in merge) and F-actin (red). EGFP-occludin (top; green in merge) and ... EGFP-occludin mice are partially protected from TNF-induced occludin redistribution, barrier dysfunction, and fluid secretion. ... Regions of the tight junction completely lacking in occludin (arrows) develop in TNF-treated wild-type but not EGFP-occludin ...http://jcb.rupress.org/content/189/1/111?ijkey=0fd6e670acc2a1bca0097826e197e7289935842c&keytype2=tf_ipsecsha
Polyamines are necessary for synthesis and stability of occludin protein in intestinal epithelial cells | Gastrointestinal and...
Measurement of occludin protein synthesis.. Occludin protein synthesis was examined by using 35S-methionine-labeling technique ... To determine the effect of polyamines on the stability of occludin, the half-life of occludin protein was examined in the ... To determine the half-life of occludin protein, cycloheximide (50 μg/ml) was added to cultures, and levels of occludin protein ... The level of newly synthesized occludin protein was measured by using 35S-methionine-labeling technique, and the occludin ...http://ajpgi.physiology.org/content/288/6/G1159
Protein Kinase Cβ Phosphorylates Occludin Regulating Tight Junction Trafficking in Vascular Endothelial Growth Factor-Induced...
... occludin fragments. B: Occludin immunoblot with polyclonal occludin antibody. ... PKCβ-mediated occludin reduction by VEGF. A: VEGF-induced loss of occludin content in retinas was prevented by PKCβ inhibitors ... PKCβ-mediated occludin modifications in rat retinas. A: Occludin IP and phospho-Ser 490 or ubiquitin blot demonstrate time ... Occludin mutants were described previously (25). In brief, Ser490 of human occludin in pENTR221 (Invitrogen, Rockville, MD) was ...http://diabetes.diabetesjournals.org/content/61/6/1573
Inhibition of Glycogen Synthase Kinase 3β Promotes Tight Junction Stability in Brain Endothelial Cells by Half-Life Extension...
Using a novel cell-based assay, inactivation of GSK3β significantly increased the half-life of occludin and claudin-5 by 32% ... occludin and claudin-5, but not claudin-3. This phenomenon was attributed to a decrease in TJ protein turnover and not ...http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055972
The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection |...
Occludin knockdown in the "donor" cells was performed to avoid cis-interactions with HCVgp and trans-interactions with occludin ... A) Occludin was silenced using shRNA technology on Huh7, PLC/PRF/5 (PLC), and 293T-Claudin-1 cells. Occludin knockdown was ... Occludin knockdown does not affect HCV initial attachment to target cells. Control or occludin shRNA-transduced Huh7 or PLC/PRF ... Control or occludin shRNA-transduced PLC/PRF/5 cells were processed for immunofluorescence with antibodies against occludin, ZO ...https://jvi.asm.org/content/83/16/8012