P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein ... creating the occludin/ZO-1/FAK/P-glycoprotein regulatory complex. Interestingly, a knockdown of P-glycoprotein by RNAi was ... This effect was mediated by changes in the protein phosphorylation status of occludin via the action of FAK, thereby affecting ... an ATP-dependent efflux drug transporter and an integrated component of the occludin/zonula occludens 1 (ZO-1) adhesion complex ...
The regulatory effects of proinflammatory cytokines (IFN-γ, IL-13, IL-17, TGF-β, TGF-α) on the expression of Occludin in ... The mean optical density of Claudin-1, Occludin and ZO-1 were 0.187 ± 0.076,0.172 ± 0.109 and 0.098 ± 0.035 respectively in the ... METHODS The expression of Claudin-1, Occludin and ZO-1 in nasal polyps (n = 20) and healthy uncinate mucosa (n = 15) were ... RESULTS The immunohistochemical results showed that Claudin-1, Occludin and ZO-1 were detected both in the nasal polyp group ...
Occludin is a protein that in humans is encoded by the OCLN gene. Occludin is a 65-kDa (522-amino acid polypeptide -human) ... "Entrez Gene: OCLN occludin". Furuse M, Hirase T, Itoh M, Nagafuchi A, Yonemura S, Tsukita S, Tsukita S (1993). "Occludin: a ... Occludin also plays an important role in the apoptosis. The C-terminus of occludin is important in receiving and transmitting ... Occludin plays a critical role in maintaining the barrier properties of a tight junction. Thus, mutation or absence of occludin ...
Occludin was the first molecular component of the tight junction to be identified. These are specialised membrane domains that ... Occludin and claudins in tight-junction strands: leading or supporting players?. Trends Cell Biol. 9 268-73 1999 ... Occludin is an ~65 kDa type II integral membrane protein, which has been shown to have four transmembrane (TM) domains, two ... since occludin-deficient cells are still able to form tight junctions when cultured in vitro [PMID: 10370242]. ...
Occludin is an integral membrane protein that localises to tight junctions [PMID: 8276896], while ELL is an elongation factor ... Occludin: a novel integral membrane protein localizing at tight junctions.. J. Cell Biol. 123 1777-88 1993 ... Occludin: a novel integral membrane protein localizing at tight junctions.. J. Cell Biol. 123 1777-88 1993 ... This represents a conserved region approximately 100 residues long within eukaryotic occludin proteins and the RNA polymerase ...
Buy our Recombinant Human Occludin protein. Ab114190 is a protein fragment produced in Wheat germ and has been validated in WB ...
Invitrogen Anti-Occludin Recombinant Monoclonal (6H10L9), Catalog # 701161. Tested in Western Blot (WB), Immunofluorescence (IF ... Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa. Occludin ... Cite Occludin Recombinant Rabbit Monoclonal Antibody (6H10L9). The following antibody was used in this experiment: Occludin ... The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at ...
Rabbit polyclonal Occludin antibody - Neural Stem Cell Marker. Validated in WB, IHC and tested in Mouse, Human. Cited in 16 ... All lanes : Anti-Occludin antibody - Neural Stem Cell Marker (ab168986) at 1 µg/ml. Lane 1 : Occludin-transfected 293T cell ... Anti-Occludin antibody - Neural Stem Cell Marker. See all Occludin primary antibodies. ... Anti-Occludin antibody - Neural Stem Cell Marker (ab168986) at 1 µg/ml + Human liver lysate at 50 µg. Secondary. Goat Anti- ...
24 antibodies to Occludin and validated for use in 6 applications (Immunohistochemistry,Flow Cytometry,Western Blot, ... Occludin Antibodies Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to ... The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at ... Occludin is thought to be involved in regulating both the localization and the function of occludin. Polyunsaturated fatty ...
Ausgesuchte Qualitäts-Hersteller für Occludin Antikörper. Hier bestellen. ... Monoklonale und polyklonale Occludin Antikörper für viele Methoden. ... occludin b , tight-junction protein , thiopurine methyltransferase , occludin , occludin-like , tight junction protein occludin ... Human Occludin (OCLN) Interaktionspartner * integration of claudin-2 (zeige CLDN2 Antikörper), occludin and ZO-1 (zeige TJP1 ...
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells.. Ploss A1, Evans MJ, Gaysinskaya VA, ... Occludin a new HCV entry factor: is the list of essential hepatitis C virus receptors complete? [Gastroenterology. 2009] ... Human occludin is a hepatitis C virus entry factor required for infection of mouse cells ... Human occludin is a hepatitis C virus entry factor required for infection of mouse cells ...
Anti-Rat Occludin (1A8) Mouse IgM MoAb. Occludin is an integral membrane protein, encoded by the OCLN gene, that is located at ... When occludin is expressed in cells that lack tight junctions, it is able to induce cell adhesion. Mutations in the OCLN gene ... Occludin is also known as BLCPMG. It is known to interact with several cytoplasmic proteins via its C terminus, while its ... This product is an affinity-purified IgG antibody that recognizes rat occludin protein. The antibody was raised in mouse using ...
Background of Occludin antibody. Kit Component:. - KN311431G1, Ocln gRNA vector 1 in pCas-Guide vector. - KN311431G2, Ocln gRNA ... Recombinant protein of human occludin (OCLN). Human. > 80 % Preparation: Recombint protein was captured through anti-DDK ... Human Lung stained with Anti-Occludin antibody Cat.-No AP15690PU. *AP15690PU-S ...
Background of Occludin antibody. Kit Component:. - KN311431G1, Ocln gRNA vector 1 in pCas-Guide vector. - KN311431G2, Ocln gRNA ... Human Lung stained with Anti-Occludin antibody Cat.-No AP15690PU. *AP15690PU-S ...
Also, testin RNAi caused the diffusion of two TJ structural proteins, occludin and ZO‐1, diffusing away from the Sertoli cell ... Association and colocalization between ZO‐1 and occludin were decreased after testin RNAi, examined by Co‐IP and ... Testin regulates the blood‐testis barrier via disturbing occludin/ZO‐1 association and actin organization. ...
Although occludin does not interact directly with virus, depletion of occludin prevents CVB entry into the cytoplasm and ... Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5 Cell Host Microbe ... Both occludin internalization and CVB entry require caveolin but not dynamin; both are blocked by inhibitors of ... Here we show that CVB does not induce major reorganization of the TJ, but stimulates the specific internalization of occludin-a ...
When human occludin is stably expressed in NRK and Rat-1 fibroblasts, which lack endogenous occludin and tight junctions but do ... Occludin-induced adhesion was next quantified using a suspended cell assay. In NRK and Rat-1 cells, occludin expression induces ... In the present study, we expressed occludin under an inducible promotor in occludin-null fibroblasts to determine whether this ... Occludin confers adhesiveness when expressed in fibroblasts Message Subject (Your Name) has sent you a message from Journal of ...
Jetzt diesen anti-Occludin Antikörper bestellen. , Produkt ABIN657822 ... Kaninchen Polyklonal Occludin Antikörper AA 446-474, C-Term für WB. Publiziert in 2 Pubmed Referenzen. ... Target Details Occludin Referenzen Bilder Handhabung Anwendungsinformationen zurück nach oben Target Details Occludin Anzeigen ... anti-Occludin Antikörper (OCLN) (AA 446-474) Occludin Antikörper (OCLN) (AA 446-474). Details for Product anti-OCLN Antibody No ...
Using a novel cell-based assay, inactivation of GSK3β significantly increased the half-life of occludin and claudin-5 by 32% ... occludin and claudin-5, but not claudin-3. This phenomenon was attributed to a decrease in TJ protein turnover and not ...
Occludin is a direct target of thyroid transcription factor-1 (TTF-1/NKX2-1). Runkle EA, Rice SJ, Qi J, Masser D, Antonetti DA ...
... occludin fragments. B: Occludin immunoblot with polyclonal occludin antibody. ... PKCβ-mediated occludin reduction by VEGF. A: VEGF-induced loss of occludin content in retinas was prevented by PKCβ inhibitors ... PKCβ-mediated occludin modifications in rat retinas. A: Occludin IP and phospho-Ser 490 or ubiquitin blot demonstrate time ... Occludin mutants were described previously (25). In brief, Ser490 of human occludin in pENTR221 (Invitrogen, Rockville, MD) was ...
Measurement of occludin protein synthesis.. Occludin protein synthesis was examined by using 35S-methionine-labeling technique ... To determine the effect of polyamines on the stability of occludin, the half-life of occludin protein was examined in the ... To determine the half-life of occludin protein, cycloheximide (50 μg/ml) was added to cultures, and levels of occludin protein ... The level of newly synthesized occludin protein was measured by using 35S-methionine-labeling technique, and the occludin ...
Jejunal epithelia were isolated from wild-type and EGFP-occludin transgenic mice. Occludin, EGFP-occludin, and actin content ... Wild-type tissue was labeled for occludin (top; green in merge) and F-actin (red). EGFP-occludin (top; green in merge) and ... EGFP-occludin mice are partially protected from TNF-induced occludin redistribution, barrier dysfunction, and fluid secretion. ... Regions of the tight junction completely lacking in occludin (arrows) develop in TNF-treated wild-type but not EGFP-occludin ...
... which differentially interact with the occludin promoter to induce expression of occludin in brain endothelium and repression ... Transcriptional control of occludin expression in vascular endothelia: regulation by Sp3 and YY1.. Biochimica et Biophysica ... Endothelium; occludin; tight junctions; differentiation; YY1; Sp3; transcription factors;. Academic Unit/School:. Faculty of ... Expression of occludin in brain endothelium corresponded with binding of Sp3 to a minimal promoter segment close to the ...
Phosphorylation of Occludin at S490 Contributes to VEGF Induced Endothelial Permeability. K. B. Gonsar; E. Felinski; J. ... protein occludin is associated with endothelial permeability and previous work has mapped 5 occludin phosphorylation sites ... We hypothesize that occludin serine 490 phosphorylation regulates endothelial permeability. Methods: : Site directed ... Phosphorylation of Occludin at S490 Contributes to VEGF Induced Endothelial Permeability. You will receive an email whenever ...