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*  Chemical Synthesis of Nucleoside Analogues | Biochemistry (Chemical Biology) | Chemistry | Subjects | Wiley
Chemical Synthesis of Nucleoside Analogues covers all the major classes of nucleosides, including pronucleotides, C-nucleosides ... 11 l-Nucleosides 473. Daniela Perrone and Massimo L. Capobianco. 12 Chemical Synthesis of Carbocyclic Analogues of Nucleosides ... 10 Synthesis of 3-Spiro-Substituted Nucleosides: Chemistry of TSAO Nucleoside Derivatives 427. Mar´ýa-Jos´e Camarasa, Sonsoles ... However, many of these nucleoside analogues have undesirable side effects. With Chemical Synthesis of Nucleoside Analogues as ...
https://www.wiley.com/en-gb/Chemical+Synthesis+of+Nucleoside+Analogues-p-9781118007518
*  British Library EThOS: Design, synthesis and biological evaluation of novel bioactive nucleosides and nucleotides
Bicyclic nucleoside analogues are a new class of anti-varicella zoster agents of which Cfl743 is the most potent anti-varicella ... One of the major issues related to nucleoside analogues is the emergence of resistance due to a lack of bioactivation to the ... At the present there are 36 approved antiviral drugs in the UK of which half are nucleoside analogues. However, the emergence ... These striking results prompted us to investigate other different nucleoside analogues, through a virtual screening using ...
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584729
*  Frontiers | Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets | Pharmacology
Two gene families are implicated in the uptake of nucleosides and nucleoside analogs into cells, SCL28 and SLC29. The former ... Two gene families are implicated in the uptake of nucleosides and nucleoside analogs into cells, SCL28 and SLC29. The former ... Some nucleoside-derived drugs can also interact with and be translocated by members of the SLC22 gene family, particularly hOCT ... Some nucleoside-derived drugs can also interact with and be translocated by members of the SLC22 gene family, particularly hOCT ...
https://www.frontiersin.org/articles/10.3389/fphar.2015.00013/full
*  Nucleoside reverse transcriptase inhibitor legal definition of nucleoside reverse transcriptase inhibitor
What is nucleoside reverse transcriptase inhibitor? Meaning of nucleoside reverse transcriptase inhibitor as a legal term. What ... Definition of nucleoside reverse transcriptase inhibitor in the Legal Dictionary - by Free online English dictionary and ... does nucleoside reverse transcriptase inhibitor mean in law? ... Usually one PI is combined with 2 nucleoside reverse ... protease inhibitors, non- nucleoside reverse transcriptase inhibitors, nucleoside/nucleotide reverse transcriptase inhibitors) ...
http://legal-dictionary.thefreedictionary.com/nucleoside+reverse+transcriptase+inhibitor
*  Identification of nucleoside diphosphate kinase from Pea microsomal membranes | Biochemical Society Transactions
Identification of nucleoside diphosphate kinase from Pea microsomal membranes. PETER M. FINAN, IAN R. WHITE, JOHN B.C. FINDLAY ... Identification of nucleoside diphosphate kinase from Pea microsomal membranes. PETER M. FINAN, IAN R. WHITE, JOHN B.C. FINDLAY ... Identification of nucleoside diphosphate kinase from Pea microsomal membranes Message Subject (Your Name) has forwarded a page ...
http://www.biochemsoctrans.org/content/20/1/10S
*  Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue
Purine nucleoside phosphorylase (PNP) in mammalian tissue is an enzyme responsible for formation of purine bases in DNA. It is ... Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. Åberg, Anna-Maja ... Analytical chemistry, myocardium, purine-nucleoside phosphorylase, enzyme activity, myocardial ischemia National Category ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:303989
*  β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction | Biochemical Journal
β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction. X M Guo, M Ashwell, M L Sinnott, T A ... β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction. X M Guo, M Ashwell, M L Sinnott, T A ... β-deuterium kinetic isotope effects in the purine nucleoside phosphorylase reaction Message Subject (Your Name) has forwarded a ... for phosphorolysis of this compound by the purine nucleoside phosphorylase of Escherichia coli as a function of pH. 3. The pH ...
http://www.biochemj.org/content/278/2/487
*  Role of Purine Nucleoside Phosphorylase in Interactions between 2′,3′-Dideoxyinosine and Allopurinol, Ganciclovir, or Tenofovir
Antiviral acyclic nucleoside phosphonate analogues as inhibitors of purine nucleoside phosphorylase. Adv. Exp. Med. Biol. 431: ... Human erythrocytic purine nucleoside phosphorylase: reaction with sugar-modified nucleoside substrates. Biochemistry 19:102-107 ... Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides. Biochem. Pharmacol. 36:1237-1244. [ ... Interactions of calf spleen purine nucleoside phosphorylase with antiviral acyclic nucleoside phosphonate inhibitors: kinetics ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC375307/?lang=en-ca
*  The SLC28 (CNT) and SLC29 (ENT) nucleoside transporter families: a 30-year collaborative odyssey | Biochemical Society...
Specialized nucleoside transporter (NT) proteins are required for passage of nucleosides and hydrophilic nucleoside analogues ... concentrative nucleoside transporter; ei, equilibrative, insensitive to inhibition by NBMPR; ENT, equilibrative nucleoside ... Physiologic nucleosides serve as central salvage metabolites in nucleotide biosynthesis, and nucleoside analogues are used as ... concentrative, NBMPR-insensitive, broadly selective for both purine and pyrimidine nucleosides; cif, concentrative, NBMPR-i ...
http://www.biochemsoctrans.org/content/44/3/869
*  Equilibrative Nucleoside Transporters
Category: Equilibrative Nucleoside Transporters. In a series of experiments with biosynthesis, long-distance transport, and ...
http://researchhunt.com/category/equilibrative-nucleoside-transporters/page/2/
*  Nucleoside diphosphate kinase B | P2X7
Nucleoside diphosphate kinase B. Interactor Gene Name:. NME2. Interactor protein name:. Nucleoside diphosphate kinase B. ... Nucleoside diphosphate kinase B (NME2) is ubiquitously expressed; it is an enzyme responsible for the synthesis of nucleoside ...
http://www.p2x7.co.uk/proteins/nucleoside-diphosphate-kinase-b/
*  Synthesis, Docking and Anti-Tumor Activity of Beta-L-1,3-Thiazolidine Pyrimidine Nucleoside Analogues - MAHE Digital Repository
Here we have described the versatile synthesis of beta-L-1,3- thiazolidine nucleoside analogues. These analogues are all ... Synthesis, Docking and Anti-Tumor Activity of Beta-L-1,3-Thiazolidine Pyrimidine Nucleoside Analogues ... a variety of strategies have been devised to design nucleoside analogues. ... 3-Thiazolidine Pyrimidine Nucleoside Analogues. Medicinal Chemistry, 3 (5). pp. 425-432. ...
http://eprints.manipal.edu/2669/
*  High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients...
Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine. Nucleosides, Nucleotides ... Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine. Nucleosides, Nucleotides ... Decitabine and physiologic nucleosides are hydrophilic, and diffusion through the cell membrane lipid layer is slow. Therefore ... Mechanisms of in vivo resistance to nucleoside analogs are complex and remain unresolved. One possibility may result from the ...
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-0817-9
*  Enzymatic production of non‐natural nucleoside‐5'-monophosphates by a novel thermostable uracil phosphoribosyltransferase
The use of enzymes as biocatalysts applied to synthesis of modified nucleoside-5'-monophosphates (NMPs) is an interesting ... Enzymatic production of non‐natural nucleoside‐5'-monophosphates by a novel thermostable uracil phosphoribosyltransferase. Arco ... Enzymatic production of non‐natural nucleoside‐5'-monophosphates by a novel thermostable uracil phosphoribosyltransferase. ...
http://abacus.universidadeuropea.es/handle/11268/6578
*  "Nucleoside reverse-transcriptase inhibitor dosing errors in an outpati" by James H. Willig, Andrew O. Westfall et al.
We evaluated factors associated with nucleoside reverse-transcriptase inhibitor dosing errors in a university-based HIV clinic ... Understanding the factors related to nucleoside reverse-transcriptase inhibitor dosing errors is an important step in the ... contributed to the higher rates of errors in nucleoside reverse-transcriptase inhibitor dosing. ... Nucleoside reverse-transcriptase inhibitor dosing errors in an outpatient HIV clinic in the electronic medical record era ...
http://escholarship.umassmed.edu/qhs_pp/818/
*  etd AT Indian Institute of Science: Structural, Functional And Transcriptional Analysis Of Nucleoside Diphosphate Kinase From...
Mycobacterial Nucleoside Diphosphate Kinase. Mycobacterium Smegmatis Nucleoside Diphosphate Kinase. Nucleoside Diphosphate ... The enzyme nucleoside diphosphate kinase (NDK) utilises an autophosporylated enzyme intermediate to catalyse the transfer of 5 ... Chapter 4. Mycobacterial Nucleoside Diphosphate Kinase Functions as GTPase Activating Protein for Mycobacterial Cytokinetic ... Maintenance of the levels of nucleoside triphosphates (NTPs) as well as their corresponding deoxy derivatives (dNTPs) is ...
http://etd.ncsi.iisc.ernet.in/handle/2005/1338
*  Bromine in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel...
Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel Monocyclic Inhibitor ... The binding sites of Bromine atom in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase ... Bromine in the structure of Crystal Structure of Schistosoma Mansoni Purine Nucleoside Phosphorylase Complexed With A Novel ...
http://bromine.atomistry.com/pdb3e0q.html
*  Human equilibrative nucleoside transporter 1 (hENT1) levels predict response to gemcitabine in patients with biliary tract...
BACKGROUND AND AIM: Translational data suggest that nucleoside transporters, in particular human equilibrative nucleoside ... BACKGROUND AND AIM: Translational data suggest that nucleoside transporters, in particular human equilibrative nucleoside ... Human equilibrative nucleoside transporter 1 (hENT1) levels predict response to gemcitabine in patients with biliary tract ... Human equilibrative nucleoside transporter 1 (hENT1) levels predict response to gemcitabine in patients with biliary tract ...
https://iris.unicampania.it/handle/11591/187804
*  中国科学院大连化学物理研究所机构知识库(DICP OpenIR): Determination of urinary nucleosides by direct injection and coupled-column
Urinary nucleosides analysis can be carried out by this procedure in 50 min requiring only pH adjustment and the protein ... Determination of urinary nucleosides was performed on Col-2 column by using a linear gradient elution comprising 25 mmol/L ... coupled-column ; urinary nucleosides ; high-performance liquid chromatography 刊名: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL ... Determination of urinary nucleosides by direct injection and coupled-column high-performance liquid chromatography[J]. JOURNAL ...
http://cas-ir.dicp.ac.cn/handle/321008/92895
*  nucleoside (CHEBI:33838)
purine nucleoside (CHEBI:26394) is a nucleoside (CHEBI:33838). pyridine nucleoside (CHEBI:47896) is a nucleoside (CHEBI:33838) ... pyrimidine nucleoside (CHEBI:26440) is a nucleoside (CHEBI:33838). ribonucleoside (CHEBI:18254) is a nucleoside (CHEBI:33838). ... nucleoside (CHEBI:33838) is a N-glycosyl compound (CHEBI:21731) nucleoside (CHEBI:33838) is a nucleobase-containing molecular ... tunicamycin A0 (CHEBI:64228) is a nucleoside (CHEBI:33838). tunicamycin A1 (CHEBI:64245) is a nucleoside (CHEBI:33838). ...
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:7647
*  Nucleosides for Oligo Synthesis | Sigma-Aldrich
Sigma-Aldrich offers a collection of useful building blocks and modified nucleosides and nucleotides for use in oligonucleotide ... nucleoside derivatives and intermediates will provide you with a useful starting point for your oligo synthetic or nucleoside ... Nucleosides are the basic structural units that make up nucleic acids (DNA and RNA), which are responsible for encoding, ... Nucleoside chemistry in general has been able to produce non-natural analogs that have been useful in medicine with ...
https://www.sigmaaldrich.com/chemistry/chemistry-products.html?TablePage=16255127
*  Nucleoside phosphorylases definition | Drugs.com
Definition of nucleoside phosphorylases. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and ... nucleoside phosphorylases. Definition: enzymes that catalyze the phosphorolysis of a nucleoside, forming the free purine or ...
https://www.drugs.com/dict/nucleoside-phosphorylases.html
*  Nucleoside Radiosensitizers | SpringerLink
Nucleoside/nucleobase analogs (bromodeoxyuridine, iododeoxyuridine, 5fluorouracil, fluorodeoxyuridine, difluorodeoxycytidine, ... Iliakis, G., and Bryant, P. E. Effects of the nucleoside analogs α-ara-A,β-ara-A and β-ara-C on cell-growth and repair of both ... McGinn, C. J., Shewach, D. S., and Lawrence, T. S. Radiosensitizing nucleo-sides. J.N.C.I., 4, 1193-1203, 1996.CrossRefGoogle ... Hammond, J. R., Lee, S., and Ferguson, P. J. [H-3]Gemcitabine uptake by nucleoside transporters in a human head and neck ...
https://link.springer.com/chapter/10.1007%2F978-1-59745-148-2_13
*  Nucleosides - Phenotypes | CTD
ethylcarboxamidoadenosine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased macrophage activation] which results in increased abundance of Nitrites ...
http://ctd.mdibl.org/detail.go?type=chem&acc=D009705&view=phenotype