High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients...High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients...

Nucleosides, Nucleotides Nucleic Acids. 2012;31:236-55.View ArticlePubMedGoogle Scholar. ... Nucleosides, Nucleotides Nucleic Acids. 2012;31:236-55.View ArticlePubMedGoogle Scholar. ... Nucleic Acids Res. 2004;32:e38.View ArticlePubMedPubMed CentralGoogle Scholar. ... One possibility may result from the presence of insufficient intracellular triphosphate, as seen for some nucleic acid analogs ...
more infohttps://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-0817-9

Nucleic Acids, Nucleotides, and Nucleosides | CTDNucleic Acids, Nucleotides, and Nucleosides | CTD

Nucleic Acids, Nucleotides, and Nucleosides Definition Complex compounds of high molecular weight occurring in living cells. ... These are basically of two types, ribonucleic (RNA) and deoxyribonucleic (DNA) acids, both of which consist of nucleotides ( ... Chemicals ← Nucleic Acids, Nucleotides, and Nucleosides Top ↑ Descendants Nucleic Acids, Nucleotides, and Nucleosides ...
more infohttp://ctd.mdibl.org/detail.go?type=chem&acc=D009706

Sugars, Derivatives Thereof, Nucleosides, Nucleotides, Nucleic AcidsSugars, Derivatives Thereof, Nucleosides, Nucleotides, Nucleic Acids

METHOD FOR SYNTHESIZING NUCLEIC ACID. Disclosed is a novel production method for efficiently and easily synthesizing an NC-type ... CROSSLINKED NUCLEIC ACID GUNA, METHOD FOR PRODUCING SAME, AND INTERMEDIATE COMPOUND. The present invention provides a method ... ACID DIFFUSION CONTROL AGENT, RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, COMPOUND, AND METHOD ... The present invention is an acid diffusion control agent consisting of at least one compound selected from among the group ...
more infohttp://www.sumobrain.com/ICL-C07H9.html

Sugars, Derivatives Thereof, Nucleosides, Nucleotides, Nucleic AcidsSugars, Derivatives Thereof, Nucleosides, Nucleotides, Nucleic Acids

OXIDATION OF URONIC ACIDS TO ALDARIC ACIDS. Disclosed is the oxidation of uronic acids, such as galacturonic acid, to the ... CATALYTIC OXIDATION OF URONIC ACIDS TO ALDARIC ACIDS. Disclosed is the oxidation of uronic acids, such as galacturonic acid, to ... The method uses oligomeric mannuronic acid as the starting material and obtains the target substance by means of steps of acid ... NOVEL PIPECOLIC ACID CO-CRYSTALS OF DAPAGLIFLOZIN AND PROCESS FOR THE PREPARATION THEREOF. The present invention discloses the ...
more infohttp://www.sumobrain.com/ICL-C07H7.html

Nucleosides, Nucleotides & Nucleic Acids - WikipediaNucleosides, Nucleotides & Nucleic Acids - Wikipedia

Nucleosides, Nucleotides & Nucleic Acids is a monthly academic journal published by Taylor & Francis since 2000, continuing the ... earlier Nucleosides and Nucleotides in series. It discusses topics relating to the biochemistry of molecules in these classes. ...
more infohttps://en.wikipedia.org/wiki/Nucleosides,_Nucleotides_&_Nucleic_Acids

KAKEN - Research Projects | identification of candidate genes responsible for an autism patient with pericentric inversion in...KAKEN - Research Projects | identification of candidate genes responsible for an autism patient with pericentric inversion in...

Nucleosides Nucleotides and Nucleic Acid. in press. (2004). *. Related Report. 2003 Annual Research Report ... Nucleosides Nucleotides and Nucleic Acid. in press. (2004). *. Related Report. 2003 Annual Research Report ... Then, we tried to further limit the breaking area by FISH, but the nucleotide sequences of both regions were too similar to ...
more infohttps://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15591252/

Antioxidant - WikipediaAntioxidant - Wikipedia

"Nucleosides, Nucleotides & Nucleic Acids. 27 (6): 608-19. doi:10.1080/15257770802138558. PMC 2895915 . PMID 18600514.. ... Uric acid[edit]. Uric acid is by far the highest concentration antioxidant in human blood. Uric acid (UA) is an antioxidant ... Besides ascorbate, medically important conditional pro-oxidants include uric acid and sulfhydryl amino acids such as ... "Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids". Biological Chemistry. 387 (4): 373-9. doi:10.1515/BC. ...
more infohttps://en.wikipedia.org/wiki/Free_radical_scavenger

Thiopurine methyltransferase - WikipediaThiopurine methyltransferase - Wikipedia

Nucleosides Nucleotides Nucleic Acids. 23 (8-9): 1385-91. doi:10.1081/NCN-200027637. PMID 15571264.. ... "Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with ...
more infohttps://en.wikipedia.org/wiki/Thiopurine_methyltransferase

Stülke J[au] - PubMed - NCBIStülke J[au] - PubMed - NCBI

Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):296-304. doi: 10.1080/15257770.2013.853783. ... Nucleic Acids Res. 2014 Jan;42(Database issue):D692-8. doi: 10.1093/nar/gkt1002. Epub 2013 Oct 30. ... Nucleic Acids Res. 2016 Jan 4;44(D1):D654-62. doi: 10.1093/nar/gkv1006. Epub 2015 Oct 3. ... Nucleic Acids Res. 2018 Jan 4;46(D1):D743-D748. doi: 10.1093/nar/gkx908. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=St%C3%BClke+J%5Bau%5D&dispmax=50

Patent US7652001 - Pharmacologically active agents containing esterified phosphonates and ... - Google PatentsPatent US7652001 - Pharmacologically active agents containing esterified phosphonates and ... - Google Patents

Nucleosides Nucleotides Nucleic Acids. Jan.-Feb. 2000;19(1-2)501-13. ... carboxylic acids, phosphoric acids, phosphinic acids, sulfonic acids, sulfinic acids and boronic acids. Pharmaceutically ... ascorbic acid, malic acid, sorbitol, phosphoric acid, thiodipropionic acid and its esters, and dithiocarbamates. ... also referred to interchangeably as nucleoside analogs, modified nucleosides, non-natural nucleosides, non-standard nucleosides ...
more infohttp://www.google.com/patents/US7652001?dq=Xerox+%2B+%22centroid

Yarmolinsky D[au] - PubMed - NCBIYarmolinsky D[au] - PubMed - NCBI

Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):767-72.. PMID:. 18066898. ... A Rationally Designed Agonist Defines Subfamily IIIA Abscisic Acid Receptors As Critical Targets for Manipulating Transpiration ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Yarmolinsky+D%5Bau%5D&dispmax=50

Baseline and changes in serum uric acid independently predict glucose control among community-dwelling women | SpringerLinkBaseline and changes in serum uric acid independently predict glucose control among community-dwelling women | SpringerLink

Background Elevated serum uric acid (SUA) levels are associated with glucose control. However, whether baseline and changes in ... Inactivation of nitric oxide by uric acid. Nucleosides Nucleotides Nucleic Acids. 2008;27(8):967-78.CrossRefPubMedPubMedCentral ... Relationship between changes in serum uric acid and follow-up HbA1c in women categorized by baseline serum uric acid. In the ... Uric acid and oxidative stress. Curr Pharm Des. 2005;11(32):4145-51.CrossRefPubMedGoogle Scholar ...
more infohttps://link.springer.com/article/10.1186%2Fs13098-018-0356-z

Antioxidante - Wikipédia, a enciclopédia livreAntioxidante - Wikipédia, a enciclopédia livre

Sautin, Yuri; Johnson, Richard (2008). «Uric Acid: The Oxidant-Antioxidant Paradox». Nucleosides, Nucleotides and Nucleic Acids ... Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids». Biological Chemistry. 387 (4): 373-9. PMID 16606334. ... Becker, B (1993). «Towards the physiological function of uric acid». Free Radical Biology and Medicine. 14 (6): 615-31. PMID ... Hornig D, Vuilleumier J, Hartmann D (1980). «Absorption of large, single, oral intakes of ascorbic acid». Int J Vitam Nutr Res ...
more infohttps://pt.wikipedia.org/wiki/Antioxidantes

Gout and Pseudogout Treatment & Management: Approach Considerations, Treatment of Acute Attacks, Treatment of Chronic GoutGout and Pseudogout Treatment & Management: Approach Considerations, Treatment of Acute Attacks, Treatment of Chronic Gout

Nucleosides Nucleotides Nucleic Acids. 2008 Jun. 27(6):585-91. [Medline]. *. Yü T, Talbott JH. Changing trends of mortality in ... Adjust the dosage upward every 2-5 weeks according to the uric acid level until the goal of a uric acid level of 6 mg/dL or ... The goal of therapy is to reduce serum uric acid levels to below 6 mg/dL, at minimum. In many cases, lowering uric acid levels ... Low-dose aspirin alters uric acid levels, increasing the risk of gout attacks and requiring close uric acid monitoring when ...
more infohttps://emedicine.medscape.com/article/329958-treatment

James C Harris, M.D.James C Harris, M.D.

Nucleosides Nucleotides Nucleic Acids. 23:1185-1187, 2004.. De Gregorio L, Jinnah HA, Harris JC, Nyhan WL, Schretlen DJ, ... Nucleotide degradation products in cerebrospinal fluid (CSF) in inherited and acquired pathologies. ...
more infohttps://www.hopkinsmedicine.org/profiles/results/directory/profile/0001820/james-harris?setsize=10&dbase=main&spec_disease=Psychiatry&CLEARPAGECACHE=false&directRef=%2Fdoctors%2Fresults%2Fdirectory%2Fprofile%2F0001820%2Fjames-harris

RCSB PDB - ADN Ligand Summary PageRCSB PDB - ADN Ligand Summary Page

... nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to ... Nucleic Acids, Nucleotides, and Nucleosides. *Nucleosides. *Organic Chemicals. *Oxidoreductases. *Peripheral Nervous System ... Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. , PMID:21059682 ... A nucleoside that is composed of adenine and d-ribose. Adenosine or adenosine derivatives play many important biological roles ...
more infohttp://www.rcsb.org/ligand/ADN

RCSB PDB - Ligand Summary PageRCSB PDB - Ligand Summary Page

... nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to ... Nucleic Acids, Nucleotides, and Nucleosides. *Nucleotides. *Polydeoxyribonucleotides. *Polynucleotides. *Pyrimidine Nucleotides ... 5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety. ... Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. , PMID: 21059682 ...
more infohttp://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=DT

Antibiotics induce redox-related physiological alterations as part of their lethality | PNASAntibiotics induce redox-related physiological alterations as part of their lethality | PNAS

Nucleosides Nucleotides Nucleic Acids 22(9):1757-1780.. OpenUrlCrossRefPubMed. *↵. Rush JD, Maskos Z, Koppenol WH (1990) ... then one would anticipate oxidative damage to nucleic acids and their building blocks during drug treatment. Although ... these results highlight the lethal effects of nucleotide oxidation. DNA incorporation of oxidized nucleotides can lead to ... 5D). Importantly, pretreatment with glutathione or ascorbic acid did not introduce growth defects (SI Appendix, Fig. S8 B and C ...
more infohttps://www.pnas.org/content/111/20/E2100?ijkey=6e71cf4de7b5baba6389b99a6d798eb927e3c97e&keytype2=tf_ipsecsha

Malaria 2012: Drugs, Vaccines, and Pathogenesis | The New York Academy of SciencesMalaria 2012: Drugs, Vaccines, and Pathogenesis | The New York Academy of Sciences

Immucillins as antibiotics for T-cell proliferation and malaria. Nucleosides Nucleotides Nucleic Acids 2004. 23(8-9):1305-11. ... Increasing concentrations of uric acid as well as other changes within the infected RBCs might be causing soluble uric acid to ... The team further found that unlike soluble uric acid, the precipitated uric acid activated human dendritic cells (DCs), up- ... form of uric acid. Electron microscopy experiments helped Rodriguez and colleagues precisely locate the uric acid precipitates ...
more infohttps://www.nyas.org/ebriefings/malaria-2012-drugs-vaccines-and-pathogenesis/

Detecting Rare Mutations with Heterogeneous Effects Using a Family-Based Genetic Random Field Method | GeneticsDetecting Rare Mutations with Heterogeneous Effects Using a Family-Based Genetic Random Field Method | Genetics

2011 Purine nucleoside phosphorylase deficiency: a mutation update. Nucleosides Nucleotides Nucleic Acids 30: 1243-1247. doi: ... 2012 Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and ... It encodes an enzyme that reversibly catalyzes the phosphorolysis of purine nucleosides. Mutations within gene PNP may lead to ... within which single nucleotide polymorphisms (SNP) were tested as a SNP-set for joint association with the simulated phenotypes ...
more infohttps://www.genetics.org/content/210/2/463

Beta-ureidopropionase deficiency - Genetics Home Reference - NIHBeta-ureidopropionase deficiency - Genetics Home Reference - NIH

Nucleosides Nucleotides Nucleic Acids. 2006;25(9-11):1093-8. Citation on PubMed ... Both beta-aminoisobutyric acid and beta-alanine are thought to play roles in the nervous system. Beta-aminoisobutyric acid ... This step converts N-carbamyl-beta-aminoisobutyric acid to beta-aminoisobutyric acid and also breaks down N-carbamyl-beta- ... Loss of this enzyme function reduces the production of beta-aminoisobutyric acid and beta-alanine, and leads to an excess of ...
more infohttps://ghr.nlm.nih.gov/condition/beta-ureidopropionase-deficiency

TYMP gene - Genetics Home ReferenceTYMP gene - Genetics Home Reference

Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1217-25. Citation on PubMed ... Thymidine is a molecule known as a nucleoside, which (after a chemical modification) is used as a building block of DNA. ... This chemical reaction is an important step in the breakdown of thymidine, which helps regulate the level of nucleosides in ... Martí R, Nishigaki Y, Vilá MR, Hirano M. Alteration of nucleotide metabolism: a new mechanism for mitochondrial disorders. Clin ...
more infohttps://ghr.nlm.nih.gov/gene/TYMP

Adenosine A3 Receptor Deficiency Exerts Unanticipated Protective Effects on the Pressure-Overloaded Left Ventricle | CirculationAdenosine A3 Receptor Deficiency Exerts Unanticipated Protective Effects on the Pressure-Overloaded Left Ventricle | Circulation

Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors. Nucleosides Nucleotides Nucleic Acids. 2006; 25: ...
more infohttp://circ.ahajournals.org/content/118/17/1713