Retinoblastoma (Rb) protein level was used as a nuclear protein loading control. D, NF-κB supershift analyses. EMSA experiments ... Retinoblastoma (Rb) protein level was used as a nuclear protein loading control. D, NF-κB supershift analyses. EMSA experiments ... Activity of Epidermal Growth Factor Receptor-Related Protein Is Mediated by Inactivation of ErbB Receptors and Nuclear Factor- ... Activity of Epidermal Growth Factor Receptor-Related Protein Is Mediated by Inactivation of ErbB Receptors and Nuclear Factor- ...
He H, Zhu D, Sun J, Pei R, Jia S (2011). "The novel protein TSR2 inhibits the transcriptional activity of nuclear factor-kappaB ... TSR2 ribosome maturation factor is a protein that in humans is encoded by the TSR2 gene. The protein encoded by this gene ... Mosk.). 45 (3): 496-502. doi:10.1134/S0026893311020099. PMID 21790011. S2CID 34475182. Gripp KW, Curry C, Olney AH, Sandoval C ... "Entrez Gene: TSR2 ribosome maturation factor". Retrieved 2020-04-12. ...
CCAAT/enhancer binding protein beta; HCC: Hepatocellular carcinoma; HNF1α: Human hepatocyte nuclear factor 1 α. ... and X protein, as well as pgRNA; (4) following nuclear export, the pgRNA is translated into the core protein and viral ... Shaul Y, Ben-Levy R, De-Medina T. High affinity binding site for nuclear factor I next to the hepatitis B virus S gene promoter ... Together, these independent findings confirm that HBV genomic nuclear factor I sites play important and complex roles in the ...
MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta ... normally functions as an inner nuclear membrane protein that antagonizes bone morphogenetic proteins and tumor growth factor- ... This autosomal dominant disorder is caused by a loss of function mutation in LEM domain-containing protein 3 (LEMD3) gene. [1, ... Iconography of Buschke Ollendorff syndrome: x ray computed tomography and nuclear magnetic resonance of osteopoikilosis]. Ann ...
Data are shown as means ± SE and corrected for the expression of ribosomal protein, large, P0. NRF1, nuclear respiratory factor ... Data are shown as means ± SE and corrected for the expression of ribosomal protein, large, P0. NRF1, nuclear respiratory factor ... nuclear genes encoding mitochondrial proteins (e.g., mitochondrial carrier proteins), and those involved in mitochondrial ... flux through the mitochondria reduce the expression of nuclear genes encoding mitochondrial proteins and transcription factors ...
It consisted of large cells with varying degrees of nuclear polymorphism and clear to basophilic cytoplasm. On ... MAL protein(+/-), Bcl-6(+/-), MUM1/IRF4(+/-), CD10(-/+), CD21(-), CD15(-), CD138(-), CD68(-), and CD3(-). Immunoglobulins were ... Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors ... and PU.1 transcription factors and the lack of IgV(H) gene crippling mutations. ...
This image depicts both nuclear and cytoplasmic MITF (melanocyte-inducing transcription factor) immunohistochemical staining ( ... A precursor protein to corticotropin and MSH is released (pro-opiomelanocortin); this protein causes the increased pigmentation ... This image depicts both nuclear and cytoplasmic MITF (melanocyte-inducing transcription factor) immunohistochemical staining ( ... and show nuclear pseudoinclusions due to nuclear membrane irregularity (see the following image). The abundant cytoplasm may be ...
... berries have gained great attention as functional food against several risk factors in chronic diseases. The number of related ... fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor ... and protein oxidation and proliferating cell nuclear antigen (PCNA) protein expression. Moreover, all the products inhibited ... Dat, N.T.; Cai, X.F.; Shen, Q.; Lee, I.S.; Kim, Y.H. New inhibitor against nuclear factor of activated T cells transcription ...
Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription ... Akt [also known as PKB (Protein kinase B) or RAC-PK (Related to the A and C kinases)] is a family of serine/threonine kinases ... Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 1996; 15(23):6541-6551. (Biology). View Reference ... Akt is activated by insulin and growth factors by a mechanism involving phosphoinositide 3-OH kinase. Phosphoinositide 3-OH ...
Nuclear factor-kappa B links carcinogenic and chemopreventive agents. Front Biosci (Schol Ed). 2009;1:45-60. ... angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett. 2008; ... Recognizing risk factors and counseling patients on how to affect risk factors such as obesity and sedentary lifestyle are ... much of the chemopreventative effect is thought to be achieved from blocking activation of nuclear factor kappa B (NFkB).83,84 ...
Mitogen-activated protein kinase-mediated disruption of enhancer-promoter communication inhibits hepatocyte nuclear factor ... Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor kappaB pathway. Biochem J. 398:439-450 ... Proteins. 64:513-523.. [Abstract]. Rizos AK, Tsikalas I, Morikis D, Galanakis P, Spyroulias GA, Krambovitis E. (2006) ... 2006) Impact of protein flexibility on hydride-transfer parameters in thermophilic and psychrophilic alcohol dehydrogenases. J ...
ROS induced by nanomaterial could result in nuclear DNA damages and leakeage of lipids, proteins and carbohydrates in the cell ... The apoptosis in cell is a highly conserved mechanism, and ROS is an important factor in the apoptotic process [45]. ... Kinetics of the formation of a protein corona around nanoparticles. Math Biosci. 2016;282:82-90. doi:10.1016/j.mbs.2016.09.018. ... A combination of bovine serum albumin with insulin-transferrin-sodium selenite and/or epidermal growth factor as alternatives ...
... mitogen-activated protein kinase 8), and RXRA (retinoic acid receptor RXR-alpha), thereby inhibiting long-chain fatty acid β- ... mitogen-activated protein kinase 8), and RXRA (retinoic acid receptor RXR-alpha), thereby inhibiting long-chain fatty acid beta ... nuclear factor kappa B subunit 1), Tnfrsf1b (TNF receptor superfamily member 1B), Ikbkb (inhibitor of nuclear factor kappa B ... STAT3 is a nuclear transcription factor that is phosphorylated and activated by JAK2 (tyrosine-protein kinase JAK2) to form an ...
... activation of the CB 1 receptor regulates renal vascular hemodynamics and stimulates the transport of ions and proteins in ... stress-related protein expression, and phosphorylation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB ... are G protein-coupled receptors that mainly signal via Gi/Go proteins, even though they may also activate Gs, Gq/11, and G ... Other factors besides HG may affect podocyte function and lead to DN, one of which is the renin-angiotensin system [68]. Indeed ...
Nuclear factor-κB (NF-κB) and activator protein-1 (AP-1) binding to DNA was quantified by ELISA in nuclear extracts using the ... and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in ... Protein expression was investigated by ELISA and immunofluorescence, transcription factor-DNA binding by ELISA, gene expression ... inflammatory and catabolic mediators could be the consequence of a lower activation of nuclear factor-κB and activator protein- ...
... an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta ... Showing Protein Inner nuclear membrane protein Man1 (HMDBP14557). IdentificationBiological propertiesGene propertiesProtein ... The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the ... an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin. J Biol Chem. 2000 ...
"Nuclear Factor 90 Proteins" by people in this website by year, and whether "Nuclear Factor 90 Proteins" was a major or minor ... "Nuclear Factor 90 Proteins" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Nuclear Factor 90 Protein Complex*Nuclear Factor 90 Protein Complex. Nuclear Factor 90 Protein*Nuclear Factor 90 Protein ... In addition to binding to RNA, nuclear factor 90 proteins form heterodimeric complexes that regulate GENETIC TRANSCRIPTION and ...
17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: Clinical ... Recently, heat shock protein (HSP)90α has been identified as an important molecular chaperone with PPARγ, which regulates the ... Furthermore, the nuclear import of PPARγ was also assessed to confirm the synergistic effect of HSP90α. Finally, the inhibitory ... Zininga T, Ramatsui L and Shonhai A: Heat shock proteins as immunomodulants. Molecules. 23(2846)2018.PubMed/NCBI View Article ...
... induced GFRα1 protein expression via nuclear factor kappa B (NF-κB) contributes to GDNF-induced Matrix metalloproteinase-9 (MMP ... activated protein kinase; NFкB, nuclear factor-kappa beta; Ape1/Ref-1, apurinic/apyrimidinic endonuclease 1; MMP-9, matrix ... Therefore, a new role for GFRα proteins can be described, in which these proteins act as ligand-induced cell adhesion molecules ... The glial cell line-derived neurotrophic factors (GDNFs), a family of neurotrophic factors, were initially thought to be able ...
... nucleocapsid protein binds to importin α proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor ... nucleocapsid protein binds to importin α proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor ... nucleocapsid protein binds to importin α proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor ... nucleocapsid protein binds to importin α proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor ...
... is a nuclear export factor, and RBM45 (Uniprot Q8IUH3) RNA-binding protein 45. It is entirely reasonable that these might be ... TATA-box binding protein, Uniprot P20226; 0.22) and YWHAZ (14-3-3 protein zeta/delta, Uniprot P63104; 0.255). However, the more ... mitoribosomal proteins; GC = 0.138), and PCBP1 (an oligo-single-stranded-dC-binding protein) GC = 0.139). Clearly their ... Tyzack, J.K., Wang, X., Belsham, G.J., and Proud, C.G. (2000). ABC50 interacts with eukaryotic initiation factor 2 and ...
17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical ... TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia. Proceedings of the National ... ASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions. Journal of ... Fc? receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and ...
This image depicts both nuclear and cytoplasmic MITF (melanocyte-inducing transcription factor) immunohistochemical staining ( ... A precursor protein to corticotropin and MSH is released (pro-opiomelanocortin); this protein causes the increased pigmentation ... This image depicts both nuclear and cytoplasmic MITF (melanocyte-inducing transcription factor) immunohistochemical staining ( ... and show nuclear pseudoinclusions due to nuclear membrane irregularity (see the following image). The abundant cytoplasm may be ...
Nuclear Markers (12) Phospho-Proteins (2) Postsynaptic proteins (4) Proteases (4) Protein Kinases/Phosphatase (10) Purinergic ... Protein Trafficking and Clearance (2) Signal Transduction (35) Stem Cells (89) Synaptic Biology (25) Transcription Factors (18 ... Adaptor Proteins (2) Adhesion Molecules (191) CD Molecules (615) Cytokine/Chemokine Receptors (103) Cytokines/Chemokines (45) ... Growth Factors (7) Immune Checkpoint Receptors (57) Innate Immune Signaling (2) MHC Antigens (23) ...
Endothelial dysfunction is a critical initiating factor contributing to cardiovascular diseases, involving the gut microbiome- ... such as the activator protein 1 (AP-1), nuclear factor-κB (NF-κB), cAMP response element-binding protein, and the ... Trimethylamine N-Oxide promotes vascular inflammation through signaling of mitogen-activated protein kinase and nuclear factor- ... In fact, dietary risk factors are key to CVD occurrence, before other common risk factors such as blood pressure or obesity, ...
Mapracorat, a selective glucocorticoid receptor agonist, upregulates RelB, an anti-inflammatory nuclear factor-kappaB protein, ... Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway.﻽. Woeller CF, ... Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis.﻽. Anderson D ... Peroxisome proliferator-activated receptor gamma ligands inhibit transforming growth factor-beta-induced, hyaluronan-dependent ...
... induced expression of c-Fos and nuclear factor of activated T cells 1 (NFATc1) via p38 mitogen-activated protein kinase ... Fexaramine Inhibits Receptor Activator of Nuclear Factor-κB Ligand-induced Osteoclast Formation via Nuclear Factor of Activated ... Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor- ... Activation of these signaling pathways induces the expression of transcription factors such as c-Fos and nuclear factor of ...
... nuclear assembly factor 1 homolog (NAF1), which is required for telomerase function [33]; centromere protein I (CENPI), which ... PLL functions as an attachment factor that enhances cell adherence due to its strong affinity for proteins and electrostatic ... The shortening of telomeres constitutes an intrinsic factor, whereas DNA damage is considered an extrinsic factor. Specifically ... M.-Y. Lee, H.-D. Hofmann, and M. Kirsch, "Expression of ciliary neurotrophic factor receptor-α messenger RNA in neonatal and ...
... and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein ... apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor- ... apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor- ... Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway. Lin YG, et ...