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*  High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity. | nanomedicines.org
Glycosylated analogues of novobiocin, discovered using a broad library of enzymes, have 100-fold improved activity against ... High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity. ... High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity.. ...
http://www.nanomedicines.org/node/24
*  gyrB - DNA gyrase subunit B - Mycobacterium smegmatis - gyrB gene & protein
... which is inhibited by ciprofloxacin and novobiocin (PubMed:12000834). Cleaves dsDNA at the sequence 5'-AT/GGCC-3', leaving a 4 ... DNA supercoiling is inhibited by the coumarin antibiotic novobiocin (PubMed:8574396). Also inhibited by the fluoroquinolones ... which is inhibited by ciprofloxacin and novobiocin (PubMed:12000834). Cleaves dsDNA at the sequence 5'-AT/GGCC-3', leaving a 4 ...
http://www.uniprot.org/uniprot/P0C559
*  SMART: Secondary literature for TOP4c domain
Novobiocin is an antibiotic which binds to a 24 kDa fragment from the B subunit of DNA gyrase. Naturally occurring resistance ... Novobiocin, a competitive inhibitor of ATP binding by gyrase, inhibits this reaction. The truncated enzyme, unlike gyrase, does ... The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA ... We have applied calorimetry to characterize the binding of novobiocin to wild-type and R136H mutant 24 kDa fragments. Upon ...
http://smart.embl.de/smart/show_secondary.cgi?domain=TOP4c
*  Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer...
Native Hsp90 complexes were identified by Native Western blot (Figure 3A). 17-AAG, novobiocin and F-4, an early novobiocin ... Hsp90prostate cancernovobiocinC-terminal inhibitorsN-terminal inhibitors. Background. Prostate cancer is generally recognized ... In contrast to N-terminal inhibitors, the coumarin antibiotic novobiocin (NB) binds to the C-terminus of Hsp90, inhibits its ... Burlison JA, Avila C, Vielhauer G, Lubbers DJ, Holzbeierlein J, Blagg BS: Development of novobiocin analogues that manifest ...
https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-11-468
*  Novobiocin - Wikipedia
Novobiocin is an aminocoumarin. Novobiocin may be divided up into three entities; a benzoic acid derivative, a coumarin residue ... Novobiocin is effective antistaphylococcal agent used in the treatment of MRSA. The molecular basis of action of novobiocin, ... which is resistant to novobiocin, in culture. Novobiocin was licensed for clinical use under the tradename Albamycin (Pharmacia ... The potency of novobiocin is considerably higher than that of the fluoroquinolones that also target DNA gyrase, but at a ...
https://en.wikipedia.org/wiki/Novobiocin
*  Novobiocin - Medical Dictionary / Glossary | Medindia
Novobiocin' - An antibiotic drug used to treat infection, is clearly explained in Medindia s glossary of medical terms ... Novobiocin - Glossary. Written & Compiled by Medindia Content Team. Medically Reviewed by The Medindia Medical Review Team on ...
https://www.medindia.net/glossary/novobiocin.htm
*  Novobiocin - DrugBank
Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra ... Novobiocin is an aminocoumarin antibiotic that was produced by the actinomycete Streptomyces niveus. Novobiocin binds to DNA ... Novobiocin. PDB Entries. 1aj6 / 1kij / 1s14 / 3lps / 4urn / 4uro / 6b89. MSDS. Download (73 KB) ... Novobiocin sodium. Q9S9NQ5YIY. 1476-53-5. WWPRGAYLRGSOSU-RNROJPEYSA-M. International/Other Brands. Albamycin. Categories. * ...
https://www.drugbank.ca/drugs/DB01051
*  Novobiocin, sodium salt - Creative Enzymes
Along with other aminocoumarin antibiotics, novobiocin is a very potent inhibitor of ba ... Novobiocin is an aminocoumarin antibiotic that is produced by Streptomyces niveus. ... Novobiocin is an aminocoumarin antibiotic that is produced by Streptomyces niveus. Along with other aminocoumarin antibiotics, ... novobiocin is a very potent inhibitor of bacterial DNA gyrase. It works by targeting the GyrB subunit of the enzyme involved in ...
https://www.creative-enzymes.com/product/Novobiocin-Sodium-Salt_2977.html
*  Novobiocin | CTD
Monosodium Salt Novobiocin , Novobiocin Calcium , Novobiocin, Monosodium Salt , Novobiocin Sodium , Sodium, Novobiocin , ... Novobiocin 2.. Chemicals ← Heterocyclic Compounds ← Heterocyclic Compounds, Fused-Ring ← Heterocyclic Compounds, 2-Ring ← ... Novobiocin CAS Type 1 Name Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4 ... Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra ...
http://ctdbase.org/detail.go?type=chem&acc=D009675
*  Get PDF - Staphylococcus arlettae new species staphylococcus equorum new species and staphylococcus kloosii new species 3 new...
... new species staphylococcus equorum new species and staphylococcus kloosii new species 3 new coagulase negative novobiocin ... nov.: three new coagulase-negative, novobiocin-resistant species from animals. Systemic and Applied Microbiology 5(4): 501-509 ... nov.: Three New Coagulase-Negative, Novobiocin-Resistant Species from Animals. Systematic and Applied Microbiology 5(4): 501- ... Coagulase-negative, novobiocin-resistant staphylococci isolated from various animals were allocated to 3 new species. Strains ...
https://eurekamag.com/research/006/472/006472805.php
*  NOVOBIOCIN SODIUM | TM Media
A valid e-mail address. All e-mails from the system will be sent to this address. The e-mail address is not made public and will only be used if you wish to receive a new password or wish to receive certain news or notifications by e-mail ...
https://www.tmmedia.in/content/novobiocin-sodium
*  Novobiocin Sodium Salt |i|BioChemica|/i| - ITW Reagents
Novobiocin and Coumermycin A1.. (2). Cozzarelli, N.R. (1980) Science 207, 953-960. DNA gyrase and the supercoiling of DNA.. (3) ... Novobiocin Sodium Salt BioChemica. Specifications:. Assay (from N): min. 95 %. α25°C/D; 5 %, MeOH/HCl: -50° - -58°. Sulfated ... Inhibition of retrovirus RNA-dependent DNA polymerase by novobiocin and nalidixic acid.. Hazard pictograms. *. ...
https://www.itwreagents.com/united-states/en/product/diagnostics/novobiocin+sodium+salt+biochemica/A1944
*  Novobiocin Differentiation Disk - for identification of Staphylococcus saprophyticus
NOVOBIOCIN DIFFERENTIATION DISKS Cat. no. Z7291 Novobiocin Differentiation Disk, 5ug 50 disks/cartridge ... Each HardyDisk™ Novobiocin Differentiation Disk is prepared by impregnating 5ug of novobiocin onto high quality 6mm diameter ... Novobiocin-resistant (zone of inhibition , 16mm). Staphylococcus saprophyticus (ATCC® 15305) growing around a HardyDisk™ ... Novobiocin-sensitive (zone of inhibition , 16mm). Staphylococcus epidermidis (ATCC® 12228) inhibition zone around a HardyDisk™ ...
https://catalog.hardydiagnostics.com/cp_prod/Content/hugo/NovobiocinDiffDisks.htm
*  NOVOBIOCIN FOR INFECTIONS DUE TO MICROCOCCUS PYOGENES | JAMA | JAMA Network
... often respond to novobiocin. The drug has been ... NOVOBIOCIN FOR INFECTIONS DUE TO MICROCOCCUS PYOGENES. William ... NOVOBIOCIN FOR INFECTIONS DUE TO MICROCOCCUS PYOGENES. JAMA. 1956;162(12):1150-1153. doi:10.1001/jama.1956.02970290046011 ... The development of resistance to novobiocin by some strains of M. pyogenes has already been observed. ... often respond to novobiocin. The drug has been used successfully in the treatment of certain cases of bacteremia, soft tissue ...
https://jamanetwork.com/journals/jama/article-abstract/318916
*  Intramuscular administration of ceftiofur sodium versus intramammary infusion of penicillin/novobiocin for treatment of...
RESULTS The cure rate at 4 weeks (91.7%) and at 8 weeks (96.8%) after initial treatment for the penicillin/novobiocin-treated ... 150 mg of novobiocin and 100,000 U of procaine penicillin G was infused daily into each mammary gland of the other 36 cows for ... compared with that for a standard treatment of intramammary infusion of penicillin/novobiocin. DESIGN Prospective, randomized, ... lower in the penicillin/novobiocin-treated group after treatment. CLINICAL IMPLICATIONS Intramuscular administration of ...
https://www.semanticscholar.org/paper/Intramuscular-administration-of-ceftiofur-sodium-of-Erskine-Bartlett/372693dff9b0caf7ca6869db8224faf7ef0dd358
*  新生霉素:Novobiocin sodium salt | SIGMA-N1628 | BSZH | 北京北实纵横科技发展
Novobiocin sodium salt. 1476-53-5. 1G. ¥1,370.00. SIGMA. N1628. 新生霉素. Novobiocin sodium salt. 1476-53-5. 5G. ¥4,510.00. SIGMA. ... Novobiocin, an inhibitor of Hsp90, is used to study heat shock protein inhibition and to produce positively supercoiled plasmid ... Novobiocin sodium salt. 1476-53-5. 250MG. ¥490.00. SIGMA. N1628. 新生霉素. ... Novobiocin inhibits DNA synthesis by inhibiting the GyrB subunit of the Topoisomerase enzyme involved in energy transduction. ...
http://www.bszh.com/dts.aspx?Key=caa2dadb-de68-4396-924d-a9893964ff6c
*  Products in Microbiological Media, HiMedia on Thomas Scientific
Novobiocin Supplement HiMedia. An antibiotic supplement for the presumptive identification of Aeromonas hydrophila . Storage ...
http://www.thomassci.com/nav/cat1/media/cat2/media_microbiologicalmedia/manufacturer/himedia/0
*  Chapter 20 Review
These questions MAY BE similar to those found on your lecture exam. THERE MAY BE MORE THAN ONE CORRECT ANSWER FOR ANY OF THE QUESTIONS BELOW ...
https://docs.google.com/forms/d/e/1FAIpQLSeLTyeuF4DwEQa0r5WqBLXwVJXooj2SGIjQpFF2H7QI182fzw/viewform?usp=sf_link
*  DailyMed - Search Results for Penicillin G
ALBADRY PLUS (novobiocin sodium and penicillin g procaine) injection, solution *This is an animal drug. ...
https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Penicillin+G
*  Microbiological indoor air quality in an office building in Gliwice, Poland: analysis of the case study | SpringerLink
Bioaerosols play a significant role in indoor air quality (IAQ) as they can be the cause of several health problems, including acute allergies and infectious diseases. This study aimed to...
https://link.springer.com/article/10.1007%2Fs11869-018-0579-z
*  Patent US8156718 - Method of preparing a packaged antimicrobial medical device - Google Patents
... novobiocin; actinomycin; rifampin; aminoglycosides such as neomycin and gentamicin; tetracyclines such as doxycycline; ...
http://www.google.com/patents/US8156718?dq=6377161