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*  Safety assessment of Apoaequorin, a protein preparation: subchronic toxicity study in rats. | CureHunter
Based on the results of this study, the No Observed-Adverse-Effect Level (NOAEL) for Apoaequorin was determined as 666.7 mg/kg ... The objective of the present study was to investigate potential adverse effects, if any, of Apoaequorin, a recombinant protein ... Any changes noted were incidental and in agreement with those historically observed in the age and strain of rats used in this ...
http://www.curehunter.com/public/pubmed23470325.do
*  Biosafety Information Centre
... effect is observed - otherwise known as the NOAEL or No Observed Adverse Effect Level.. Christian Vélot, who led the study, ... The Roundup formulation contained 450g/l of glyphosate, a 'No Observed Adverse Effect Level'. The results showed that even at ... nidulans exposed to R450 at a dose corresponding to the no-observed-adverse-effect level (NOAEL) for macroscopic parameters ( ... But Vélot says the fact that molecular and metabolic effects were observed at doses without visible toxicity suggests that this ...
https://biosafety-info.net/article.php?aid=1438
*  TIPS CHANNEL: Canned soup ups BPA levels 1200% in urine
"Previous studies have linked elevated BPA levels with adverse health effects. The next step was to figure out how people are ... "The magnitude of the rise in urinary BPA we observed after just one serving of soup was unexpected and may be of concern among ... that consumption of a serving of canned soup daily was associated with a 1,221 percent increase in BPA compared to levels in ...
http://tipschannel.blogspot.com/2011/11/canned-soup-ups-bpa-levels-1200-in.html
*  No-observed-adverse-effect level - Wikipedia
Lowest-observed-adverse-effect level Engelhardt JA, Dorato MA (August 2005). "The no-observed-adverse-effect-level in drug ... The no-observed-adverse-effect level (NOAEL) denotes the level of exposure of an organism, found by experiment or observation, ... some effects may be produced at this level, but they are not considered as adverse, or as precursors to adverse effects. In an ... "Relation between benchmark dose and no-observed-adverse-effect level in clinical research: Effects of daily alcohol intake on ...
https://en.wikipedia.org/wiki/No-observed-adverse-effect_level
*  Lowest-observed-adverse-effect level - Wikipedia
The lowest-observed-adverse-effect level (LOAEL) is the lowest concentration or amount of a substance found by experiment or ... No-observed-adverse-effect level Reference dose "IUPAC glossary of terms used in toxicology - terms starting with L". ... lowest level of a chemical stressor evaluated in a toxicity test that shows harmful effects on a plant or animal. While LOAELs ... Federal agencies use set approval standards below this level. The United States Environmental Protection Agency defines LOAEL ...
https://en.wikipedia.org/wiki/Lowest-observed-adverse-effect_level
*  Gene Expression - Contract Pharma
No Observed Adverse Effect Level (NOAEL) A dose in toxicology studies that produces no adverse effects.… ... The parameters tested in these studies may include specificity, matrix effects, linearity, robustness, etc. Results… ...
http://www.contractpharma.com/contents/view_glossary/2012-02-27/gene-expression/
*  Screening of new Monsanto Papers | Corporate Europe Observatory
how Monsanto is trying at all cost to get regulators to stick to their preferred No Observed Adverse Effect Level (NOAEL) for ... 3. JMPR and the No Observed Adverse Effect Level (NOAEL). In 2003, Stephen Wratten, Mark Martens and Donna Farmer of Monsanto ... "no observed adverse effect level".. On page 4, Wratten says: "I believe their [sic] needs to be a harsher dismissal of the ... To this effect, he suggests to change the sentence in the study as follows: "In the rabbit, doses above 175 mg/kg were ...
https://corporateeurope.org/en/food-and-agriculture/2017/11/screening-new-monsanto-papers
*  Classification and Technological Purposes of Food Additives: The European Point of View | SpringerLink
No Observed Adverse Effect Level. O2. Oxygen. PHB. p-hydroxybenzoic acid ... EFSA (2013b) EFSA completes full risk assessment on Aspartame and Concludes it is safe at current level of exposure. European ...
https://link.springer.com/chapter/10.1007/978-3-319-57042-6_1
*  Glossary of Terms
No Observed Adverse Effect Concentration NOAEL See No Observed Adverse Effect Level NOEC No Observed Effect Concentration NOEL ... Lowest Observed Adverse Effect Level (LOAEL) The lowest dose in a study at which an effect (or effects) is considered to be ... No Observed Adverse Effect Level (NOAEL) The highest exposure level in a toxicity study at which there are no statistically ... See Lowest Observed Adverse Effect Level Local Environment Risk Assessment for Pesticides (LERAP) A Local Environmental Risk ...
http://www.hse.gov.uk/pesticides/topics/resources/glossary.htm
*  List of Abbreviations | Waste Incineration and Public Health | The National Academies Press
no-observed-adverse-effect level. NOx. oxides of nitrogen. NO2 ... Biographical Information on the Committee on Health Effects of ... The book also examines some of the social, psychological, and economic factors that affect the communities where incineration ... Tools and approaches for assessing possible human health effects.. *Scientific concerns pertinent to future regulatory actions. ... takes place and addresses the problem of uncertainty and variation in predicting the health effects of incineration processes. ...
https://www.nap.edu/read/5803/chapter/14
*  Index | Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride | The National Academies Press
No-Observed-Adverse-Effect Level (NOAEL). calcium, 137-138, 140. defined, 57 ... Tolerable Upper Intake Levels (ULs). Intakes below the UL are unlikely to pose risks of adverse health effects in healthy ... 3 A Model for the Development of Tolerable Upper Intake Levels 51-70 ... may affect how it works, and how the nutrient may be related to chronic disease. ...
https://www.nap.edu/read/5776/chapter/19
*  An In Silico Approach for Evaluating a Fraction-Based, Risk Assessment Method for Total Petroleum Hydrocarbon Mixtures
... as both have similar lowest-observed-adverse-effect levels (LOAELs) of 291 and 331 mg/kg-day, no-observed-adverse-effect levels ... No-observed-adverse-effect level. LOAEL:. Lowest-observed-adverse-effect level. MADEP:. Massachusetts Department of ... However, we also observed some discrepancies between our results and those of MADEP. For instance, MADEP includes the C5-C8 ... Because most TPHs are postulated to have similar toxic effects or modes of action (e.g., toxicity, binding affinity, etc.), a ...
https://www.hindawi.com/journals/jt/2012/410143/
*  KAKEN - Research Projects | DEVELOPMENT OF STATISTICAL THEORY AND ITS APPLICATION FOR COMPLEX NONLINEAR DATA (KAKENHI-PROJECT...
Publications] Yanagawa,T.and Kikuchi,Y.: 'Statistical issues on the determination of the No-Observed-Adverse-Effect levels in ... Publications] Yanagawa,T.and Kikuchi,Y.: 'Statistical issues on the determination of the No-Observed-Adverse-Effect levels in ... Publications] Yanagawa, T.and Kikuchi, Y.: 'Statistical issues on the determination of the No-Observed-Adverse-Effect levels in ... Publications] Sakata,T.and Yanagawa,T.: 'Determination of the No-Observed-Adverse Effect level by controlling over-estimation ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09440083/
*  Federal Register :: Spinetoram; Pesticide Tolerances
LOC = level of concern. mg/kg/day = milligram/kilogram/day. MOE = margin of exposure. NOAEL = no-observed-adverse-effect-level ... the studies received and the nature of the adverse effects caused by spinetoram as well as the no-observed-adverse-effect-level ... and the lowest-observed-adverse-effect-level (LOAEL) from the toxicity studies can be found at http://www.regulations.gov in ... or left in effect, demonstrating that the levels in food are not above the levels anticipated. For the present action, EPA will ...
https://www.federalregister.gov/documents/2018/08/08/2018-16989/spinetoram-pesticide-tolerances
*  Federal Register :: Metconazole; Pesticide Tolerances
LOAEL= lowest observed adverse effect level. NOAEL = no observed adverse effect level. ... "adverse" and formed the basis of the study lowest observed adverse effect levels (LOAELs). Metconazole is considered ... The chronic Reference Dose of 0.04 mg/kg/day based on the 2-year chronic rat study with a no observed adverse effect level ( ... rat and dog at dose levels where liver effects were also observed. In dogs, lenticular degeneration (cataracts) was observed at ...
https://www.federalregister.gov/documents/2012/05/04/2012-10689/metconazole-pesticide-tolerances
*  Ultram (Tramadol Hcl): Side Effects, Interactions, Warning, Dosage & Uses
... side effects, drug interactions, warnings, patient labeling, reviews, and related medications. ... APAP = acetaminophen; B.W. = body weight; NOAEL = no-observed-adverse-effect level; p.o. = oral; ↑ = increased; ↓ = decreased. ... No effects on fertility were observed for tramadol at oral dose levels up to 50 mg/kg (300 mg/m²) in male rats and 75 mg/kg ( ... SIDE EFFECTS. Adverse Drug Reaction Overview. The most commonly reported adverse reactions are dizziness, nausea, constipation ...
https://www.rxlist.com/ultram-drug.htm
*  Pesticide residues in food - 2002 - Introduction
1.Pesticide residues - toxicity 2.Food contamination 3.No-observed-adverse-effect level I.FAO Panel of Experts on Pesticide ... Dr E. Mendez, Health Effects Division, Office of Pesticide Programs, Environmental Protection Agency, Washington DC, USA (WHO ... Dr Whang Phang, Health Effects Division, Office of Pesticide Programs, Environmental Protection Agency, Washington DC, USA (WHO ... Dr V.L. Dellarco, Environmental Protection Agency, Office of Pesticide Programs, Health Effects Division, Washington DC, USA ...
http://www.inchem.org/documents/jmpr/jmpmono/2002pr01.htm
*  Glossary: PCBs
No Observed Adverse Effect Level. The highest tested dose of a substance that has been reported to have no harmful (adverse) ... Lowest Observed Adverse Effect Level. The lowest tested dose of a substance that has been reported to cause harmful (adverse) ... Ground-level ozone: At ground level (in the troposphere), ozone is considered an air pollutant that can seriously affect the ... Toxic substances can cause adverse health effects. (Source: GreenFacts) Tumour. An abnormal mass of tissue resulting from ...
http://www.greenfacts.org/en/pcbs/glossary-pcbs.htm
*  Pesticide residues in food-2003 (JMPR 2003)
1.Pesticide residues toxicity 2.Food contamination 3.No-observed-adverse-effect level I. FAO Panel of Experts on Pesticides ... no-observed-adverse-effect level. NOEL. no-observed-effect level. OECD. Organization for Economic Co-operation and Development ... Dr S. Funk, Health Effects Division, United States Environmental Protection Agency, Washington DC, USA (Vice-Chairman) ... Dr V.L. Dellarco, United States Environmental Protection Agency, Office of Pesticide Programs, Health Effects Division, ...
http://inchem.org/documents/jmpr/jmpmono/v2003pr01.htm
*  Glossary: Boron
No Observed Adverse Effect Level. The highest tested dose of a substance that has been reported to have no harmful (adverse) ... health effects. (Source: GreenFacts) Toxicity. The capacity or property of a substance to cause adverse effects. (Source: ... Adverse health effect. A change in body function or cell structure that might lead to disease or health problems. (Source: ... The study of the harmful effects of substances on humans or animals. (Source: ATSDR Glossary of Terms ) ...
http://www.greenfacts.org/en/boron/glossary-boron.htm
*  Fluoride Action Network | The toxicity of Sulfoxaflor
LOC = level of concern. mg/kg/day = milligram/kilogram/day. MOE = margin of exposure. NOAEL = no-observed-adverse-effect-level ... Study and toxicological effects. FQPA SF = Food Quality Protection Act Safety Factor. LOAEL = lowest-observed-adverse-effect- ... Effects in the male reproductive organs were observed in the chronic/carcinogenicity study in rats that included increased ... Since the neurotoxicity was observed only at a very high dose and many of the effects are not consistent with the perturbation ...
https://fluoridealert.org/content/sulfoxaflor-toxicity/
*  Glossary - Household Products Database
Lowest Observed Adverse Effect Level. The lowest dose in a study in which there was an observed toxic or adverse effect. ... No Observed Adverse Effect Level. The highest dose in a toxicity study at which there were no toxic or adverse effects observed ... Generally, acute effects will be evident within 14 days. Acute Health Effect. An adverse health effect resulting from a single ... Chronic Health Effect. An adverse health effect resulting from long-term exposure to a substance. ...
https://hpd.nlm.nih.gov/householdGlossary.htm
*  Plus it
no observed adverse effect level. PF-3893787. (R)-N4-(cyclopropylmethyl)-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4- ... In the GLP 3-month oral toxicity study in rats (0, 10, 50, and 250 mg/kg per day), the no observed adverse effect level (NOAEL ... No compound-related adverse effects were observed in males at any dose or duration or in females at any dose for 3 months. ... No deaths, serious adverse events, discontinuations due to adverse events, or other significant adverse events occurred. ...
http://jpet.aspetjournals.org/content/349/2/176
*  Lombardo A[au] - PubMed - NCBI
CORAL: model for no observed adverse effect level (NOAEL).. Toropov AA, Toropova AP, Pizzo F, Lombardo A, Gadaleta D, Benfenati ...
https://www.ncbi.nlm.nih.gov/pubmed?access_num=Lombardo+A&link_type=AUTHORSEARCH&cmd=search&term=Lombardo+A%5Bau%5D&dispmax=50
*  RoundupandBirthDefectsv5 | Congenital Disorder | Herbicide
observed adverse effect level, the level at which the 4.2. EFSA undermines democratic. effect being looked for is not found). ... anomalies was high in all treatment groups, NOAEL (no observed adverse effect level). In this. including the low-dose level of ... NOAEL (no observed adverse effect level). In other. Based on this biased selection of data, words, even the lowest dose ... effects observed in independent studies on EFSA refuses to take decisive action restricting. BPA, such as some adverse effects ...
https://www.scribd.com/doc/57277946/RoundupandBirthDefectsv5