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*  Mechlorethamine - DrugBank
Organic nitrogen compounds. Class. Organonitrogen compounds. Sub Class. Nitrogen mustard compounds. Direct Parent. Nitrogen ... This compound belongs to the class of organic compounds known as nitrogen mustard compounds. These are compounds having two ... Aliphatic acyclic compounds. External Descriptors. organochlorine compound, nitrogen mustard (CHEBI:28925) Targets. 1. DNA ... Nitrogen mustard / Tertiary aliphatic amine / Tertiary amine / Organopnictogen compound / Hydrocarbon derivative / ...
https://www.drugbank.ca/drugs/DB00888
*  Mustard Gas
It is an organic compound related to sulfur mustard and nitrogen mustard. Lewisite is an arsenic-containing agent, and like ... Mustard gas has been uses as a chemical weapon during combat in World War I, World War II, and the Iran-Iraq war in the 1980s. ... Filing a Mustard Gas Related Claim. The VA has recently relaxed some of their strict qualification requirements for filing a ... If you served in the military and have suffered due to the exposure of mustard gas, contact Jan Dils, Attorneys at Law today at ...
https://www.fight4vets.com/disabilities/mustard-gas/
*  Injury Induced by Chemical Warfare Agents: Characterization and Treatment of Ocular Tissues Exposed to Nitrogen Mustard | IOVS ...
... in copper levels 7 and a decrease in ascorbic acid within the anterior chamber 8 after ocular exposure to mustard compounds, ... Williams, RN, Bhattacherjee, P. (1984) Inhibition of the acute ocular responses to nitrogen mustard by colchicines Exp Eye Res ... Gonzalez, GG, Gallar, J, Belmonte, C. (1995) Influence of diltiazem on the ocular irritative response to nitrogen mustard Exp ... Mustard agents are among the most powerful tactical chemical weapons that exist today. Sulfur mustard was first used in Ypres, ...
http://iovs.arvojournals.org/article.aspx?articleid=2182145
*  Chemical Weapons Primer - Wisconsin Project on Nuclear Arms Control
Mustard gas is a colorless oily liquid with a garlic odor; nitrogen mustards are amber liquids with a fishy smell; lewisite is ... Military Chemistry and Chemical Compounds, Field Manual 3-9 (October 1974); U.S. General Accounting Office, Arms Control: U.S. ... Blister agents, such as mustard gas, nitrogen mustards and lewisite, attack and destroy the skin and body tissues. They cause ... Mustard gas was nevertheless used during the Iran-Iraq War and is still a viable chemical agent. At the least, obliging the ...
http://www.wisconsinproject.org/chemical-weapons/
*  Chlorambucil : usage, side effects, expert advice and chlorambucil based medicines | 1mg
Chlorambucil belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with ... Chlorambucil is metabolized in liver to form nontoxic compounds which are excreted in urine ...
https://www.1mg.com/generics/chlorambucil-209564
*  Organophosphorus compounds as chemical warfare agents: a review
... which are compounds that cause irritation and vesication of the skin and mucous membranes (mainly the lungs), being the mustard ... Phosphorus is an extremely versatile element, located below nitrogen in Group V of the Periodic Table. Its general application ... 4.1 Organophosphorus compounds. Neurotoxic chemical warfare agents are essentially organophosphorus compounds (OPCs) that ... 2. Black, R. M.; Harrison, J. M. In The Chemistry of Organophosphorus Compounds, Vol 4, Ter- and Quinque- phosphorus Acids and ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000300003&lng=en&nrm=iso&tlng=en
*  mechlorethamine
... is used to treat the symptoms of several types of cancer. Mechlorethamine treats only the symptoms of cancer but does not treat the cancer itself. Mechlorethamine is also sometimes injected into body spaces around the heart, lungs, or stomach to treat fluid retention in these areas caused by cancer...
http://www.healthbanks.com/PatientPortal/MyPractice.aspx?UAID=74FFEE33-2050-4F3A-981A-083E51DED8D6&ID=HW5d01339a1&Title=mechlorethamine
*  Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin...
Nitrogen Mustard Compounds. Podophyllotoxin. Antibodies. Immunoglobulins. Antibodies, Monoclonal. Antineoplastic Agents. ... Patient is currently participating or has participated in a study with an investigational compound or devise within 30 days of ... patients who have received such compounds for other indications, e.g. valproic acid for epilepsy, may enroll after a 30-day ... patients who have received compounds with HDAC inhibitor-like activity, such as valproic acid, as anti-tumor therapy should not ...
https://clinicaltrials.gov/ct2/show/NCT00992446?cond=%22mycosis+fungoides%22&rank=15
*  Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High...
Nitrogen Mustard Compounds. Liposomal doxorubicin. Etoposide phosphate. Carboplatin. Doxorubicin. Etoposide. Vincristine. ...
https://clinicaltrials.gov/ct2/show/NCT00567567
*  Anti-CD20 Radioimmunotherapy Before Chemotherapy and Stem Cell Transplant in Treating Patients With High-Risk B-Cell...
Nitrogen Mustard Compounds. Biotin. Antineoplastic Agents, Phytogenic. Antineoplastic Agents. Topoisomerase II Inhibitors. ...
https://www.clinicaltrials.gov/ct2/show/NCT02483000
*  Complement Component 6 Deficiency disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Nitrogen Mustard Compounds. Phase 2. 21. Protein Kinase Inhibitors. Phase 2. 22. tyrosine. Nutraceutical. Phase 2. ...
https://www.malacards.org/card/complement_component_6_deficiency
*  Find Research Outputs - MD Anderson Cancer Center
Nitrogen Mustard Compounds Patient Isolators Folic Acid Antagonists Carbenicillin Spontaneous Remission 3 Citations (Scopus) ...
https://mdanderson.elsevierpure.com/en/publications/?format=&page=3671
*  Ofatumumab Cardiac Repolarization (QTc) Study in Fludarabine-Refractory Chronic Lymphocytic Leukemia Subjects
A nitrogen mustard compound that functions as an ALKYLATING ANTINEOPLASTIC AGENT and is used in the treatment of CHRONIC ... Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual ... A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. ...
https://www.bioportfolio.com/resources/trial/65680/Ofatumumab-Cardiac-Repolarization-QTc-Study-in-Fludarabine-Refractory-Chronic-Lymphocytic-Leukemia-Subjects.html
*  Cyclophosphamide Plus Topotecan in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia
A nitrogen mustard compound that functions as an ALKYLATING ANTINEOPLASTIC AGENT and is used in the treatment of CHRONIC ... Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to ... Cyclophosphamide is a prodrug that is converted to inactive carboxy-cyclophosphamide, acrolein and phosphoramide mustard, an ... agent that adds alkyl groups to oxygen and nitrogen atoms of guanine, one o... ...
https://www.bioportfolio.com/resources/trial/126218/Cyclophosphamide-Plus-Topotecan-in-Treating-Patients-With-Refractory-or-Relapsed-Acute-Myelogenous.html
*  anthrax
Organic sulfur and nitrogen compounds (mustard gases): e.g. S-Lost (HD); N-Lost (HN); Lewisite (L); ... Organic phosphoric acid compounds: e.g. Tabune; Sarine; Somane; Tammelin Esters (VX) ... Organic arsenic compounds: e.g. Dichloro-(2-chlorovinyl) arsine; Ethylarsine dichloride; Methylarsine dichloride ...
http://www.menstuff.org/issues/byissue/anthrax.html
*  Emcyt Product NDC number 0013-0132 (estramustine phosphate sodium Drug) - Medical Code Data
Pharm Classes: Alkylating Activity [MoA],Alkylating Drug [EPC],Estradiol [Chemical/Ingredient],Nitrogen Mustard Compounds [ ... compounded, or processed for commercial distribution in the United States. An NDC number for a specific drug is created by the ...
https://medcodedata.com/product-ndc-number-0013-0132-nda018045/
*  Plus it
Goodman and Gilman carried out experiments in mice bearing a transplanted lymphoid tumor with one compound, nitrogen mustard. ... The use of nitrogen mustard for lymphomas spread rapidly throughout the United States after the publication of the Lindskog ... Nitrogen mustard therapy: use of methyl-bis (β-chloroethyl) amine hydrochloride and tris (β-chloroethyl)amine hydrochloride for ... The 1950s were a period of undue pessimism due to the disappointment over the failed promise of nitrogen mustard to produce ...
http://cancerres.aacrjournals.org/content/68/21/8643
*  Cyclosphosphamide | definition of Cyclosphosphamide by Medical dictionary
An alkylating agent with antitumor activity and uses similar to those of its parent compound, nitrogen mustard (mechlorethamine ... An alkylating agent with antitumor activity and uses similar to those of its parent compound, nitrogen mustard (mechlorethamine ... Alkylating agent with antitumor activity and uses similar to those of its parent compound, nitrogen mustard. ... a cytotoxic alkylating agent, one of the nitrogen mustards, used in antineoplastic therapy for a wide variety of conditions, ...
http://medical-dictionary.thefreedictionary.com/Cyclosphosphamide
*  MEDICATION DEPOT FOR MEDICAL IMPLANTS - Patent application
... in particular nitrogen mustard compounds and nitrosourea compounds; platinum compounds; hydroxyurea compounds; anti-metabolites ...
http://www.patentsencyclopedia.com/app/20110178593
*  TRITURATION OFMUSTARGEN®(Mechlorethamine HCl for Injection) - Drug label and information - Rx Drugs Info
Taylor, L.: A technique for intrapleural administration of nitrogen mustard compounds, Amer. J. Med. Sci. 233: 538-541, May ... MUSTARGEN, an antineoplastic nitrogen mustard also known as HN2 hydrochloride, is a nitrogen analog of sulfur mustard. It is a ... As nitrogen mustard therapy may contribute to extensive and rapid development of amyloidosis, it should be used only if foci of ... The usual dose of nitrogen mustard for intracavitary injection is 0.4 mg/kg of body weight, though 0.2 mg/kg (or 10 to 20 mg) ...
http://rxdrugsinfo.com/drug-info-label/mustargen
*  Carmustine - Wikipedia
It is a nitrogen mustard β-chloro-nitrosourea compound . As a dialkylating agent, carmustine can form interstrand crosslinks in ... is a medication used mainly for chemotherapy It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent ...
https://en.wikipedia.org/wiki/Carmustine
*  Thiotepa - Wikipedia
... compounds with nitrogen-mustard-like activity". Cancer. 6 (1): 142-148. doi:10.1002/1097-0142(195301)6:1. 3.0.CO;2-W. Kim, Kyu- ... Thiotepa is an organophosphorus compound with the formula SP(NC2H4)3. It is a analog of N,N′,N′′-triethylenephosphoramide (TEPA ...
https://en.wikipedia.org/wiki/Thiotepa
*  Browsing Cancer Therapeutics by issue date
Nine new nitrogen mustard compounds derived from 2,6-difluoro-4-hydroxy- (3a-e) and 2,6-difluoro-4-amino- (4a-d) aniline were ... aniline nitrogen mustards in gene-directed enzyme prodrug therapy systems.  Niculescu-Duvaz, I; Scanlon, I; Niculescu-Duvaz, D ... We describe herein the antitelomerase and antitumor properties of a small-molecule compound designed by ... ...
https://repository.icr.ac.uk/handle/internal/4/browse?type=dateissued
*  Report | CAMEO Chemicals | NOAA
This compound is a nitrogen mustard. It is highly irritating to skin, eyes, and mucous membranes. Nitrogen mustards have ... HN1 (nitrogen mustard-1); [Bis(2-chloroethyl)ethylamine] 538-07-8. CUM 100 grams. CW/CWP. ... Nitrogen mustard-1; (Ethylbis(2-chloroethyl)amine; Bis(2-chloroethyl)ethylamine) (538-07-8) 0.002 mg/m3 0.022 mg/m3 0.37 mg/m3 ... Interim AEGLs for Nitrogen Mustard-1 (538-07-8) Exposure Period. AEGL-1. AEGL-2. AEGL-3. ...
https://cameochemicals.noaa.gov/report?key=CH4991
*  Come è bella mia citta, comment elle est belle ma ville! (24.12.2007), Photos et images El Jadida
... gravis is unknown.hypertensive heart diseaseAfter World War II medical research continued into nitrogen mustard compounds.There ... MelisThese emerging agents have potential utility not only as biologi cal probes for preclinical studies but also as lead com pounds ...
http://www.eljadida.com/galerie/photo-membres-el-jadida-85-0-0.html