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*  PLOS ONE: Compensatory Feto-Placental Upregulation of the Nitric Oxide System during Fetal Growth Restriction
... and of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine. Umbilical vein endothelial cells were also ... Methods Prenatal assessment of feto-placental vascular function was combined with measurement of nitric oxide (in the form of S ... Conclusion Fetal growth restriction is typified by increased nitric oxide production during pregnancy and after birth. This ... demonstrate any abnormality in the nitric oxide system. ...
http://journals.plos.org/plosone/article/comments?id=10.1371/journal.pone.0045294
*  Patent US6147109 - Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA ... - Google Patents
HMG-CoA reductase inhibitors are found to upregulate endothelial cell Nitric Oxide Synthase activity through a mechanism other ... preventing conditions that result from the abnormally low expression and/or activity of endothelial cell Nitric Oxide Synthase ... Nitric Oxide Synthase is the enzyme that catalyzes the reaction that produces nitric oxide from the substrate L-arginine. As ... cell Nitric Oxide Synthase and/or a nonHMG-CoA reductase inhibitor agent that increases endothelial cell Nitric Oxide Synthase ...
http://www.google.com/patents/US6147109?dq=%22robert+sheehan%22
*  Nitric oxide synthase activity is increased in relation to the severity of liver dysfunction | Clinical Science
Nitric oxide synthase activity was measured using the conversion of oxyhaemoglobin to methaemoglobin by nitric oxide and ... The hyperdynamic circulation of cirrhosis has been linked to nitric oxide.. 2.We measured neutrophil nitric oxide synthase ... Nitric oxide synthase activity is increased in relation to the severity of liver dysfunction. Helen F. GALLEY, David ... 5.Our results show that nitric oxide synthase activity increases with increasing Child-Pugh score and is associated with the ...
http://www.clinsci.org/content/95/3/355
*  Indazoles - Halogenated Heterocycles | Sigma-Aldrich
... and nitric oxide synthase inhibitors. The presence of a halogen allows these reagents to be used as substrates in various ... and nitric oxide synthase inhibitors. The presence of a halogen allows these reagents to be used as substrates in various ...
https://www.sigmaaldrich.com/chemistry/chemistry-products.html?TablePage=16269140
*  Patent US6180597 - Upregulation of Type III endothelial cell nitric oxide synthase by rho ... - Google Patents
... rho GTPase function inhibitors are found to upregulate endothelial cell Nitric Oxide Synthase activity. As a result, rho GTPase ... preventing conditions that result from the abnormally low expression and/or activity of endothelial cell Nitric Oxide Synthase ... Nitric Oxide Synthase is the enzyme that catalyzes the reaction that produces nitric oxide from the substrate L-arginine. As ... Nitric Oxide Synthase and/or a non-rho GTPase function inhibitor agent that increases endothelial cell Nitric Oxide Synthase ...
http://www.google.ca/patents/US6180597
*  Inducible and endothelial nitric oxide synthase expression during development of transplant arteriosclerosis in rat aortic...
Inducible and endothelial nitric oxide synthase expression during development of transplant arteriosclerosis in rat aortic ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:79783
*  Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by...
The endogenous NO synthase inhibitor asymmetric dimethylarginine (ADMA) circulates in plasma, and its concentrations are ... the activity of which regulates ADMA concentrations and provides a mechanism for modulating NO synthase in vivo. We ... BACKGROUND Nitric oxide (NO) plays an important part in lowering pulmonary vascular resistance after birth, and in persistent ... Birth upregulates nitric oxide synthase activity in the porcine lung.. *F I Arrigoni. , A A Hislop. , J S Pollock. , S G ...
https://www.semanticscholar.org/paper/Metabolism-of-asymmetric-dimethylarginines-is-regu-Arrigoni-Vallance/74611773c3ba9297c156b631e871167fe32983b2
*  Research programme: neuronal nitric oxide synthase inhibitors - Pfizer - AdisInsight
Pfizer was undertaking a research programme to develop a series of centrally-active and selective neuronal nitric oxide ... Mechanism of Action Nitric oxide synthase inhibitors * Orphan Drug Status Orphan designation is assigned by a regulatory body ... Research programme: neuronal nitric oxide synthase inhibitors - Pfizer Alternative Names: CP 536404; CP 601073; CP 695516 ...
http://adisinsight.springer.com/drugs/800023672?error=cookies_not_supported&code=74511f4b-75c2-4aee-9f6c-aa01a8185e20
*  Nitric oxide synthase - Wikipedia
Biological functions of nitric oxide Nitric-oxide synthase (NAD(P)H-dependent) Nitric oxide synthase 2 (inducible) PDB: 3N5P​; ... Nitric oxide synthases (EC 1.14.13.39) (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L- ... "Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression". Arch Surg. 132 (11): 1177-83. doi: ... which is then recaptured to enable nitric oxide release. The first nitric oxide synthase to be identified was found in neuronal ...
https://en.wikipedia.org/wiki/Nitric_oxide_synthase
*  Neuronal Nitric Oxide Synthase | IntechOpen
... regulates nitric oxide (NO) synthesis that has dual biological activities: as an important signalling molecule in ... Neuronal Nitric Oxide Synthase, Nitric Oxide Synthase - Simple Enzyme-Complex Roles, Seyed Soheil Saeedi Saravi, IntechOpen, ... Neuronal Nitric Oxide Synthase, Nitric Oxide Synthase - Simple Enzyme-Complex Roles, Seyed Soheil Saeedi Saravi, IntechOpen, ... Nitric oxide synthase (NOS), a flavo‐hemoprotein, regulates nitric oxide (NO) synthesis that has dual biological activities: as ...
https://www.intechopen.com/books/nitric-oxide-synthase-simple-enzyme-complex-roles/neuronal-nitric-oxide-synthase
*  Nitric oxide synthase 2 (inducible) - Wikipedia
Nitric oxide synthase, inducible is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide is a reactive free ... "Entrez Gene: NOS2A nitric oxide synthase 2A (inducible, hepatocytes)". Felley-Bosco E, Bender FC, Courjault-Gautier F, Bron C, ... Nitric oxide synthase 2A has been shown to interact with Caveolin 1 and Rac2. GRCh38: Ensembl release 89: ENSG00000007171 - ... This gene encodes a nitric oxide synthase which is expressed in the liver and is inducible by a combination of ...
https://en.wikipedia.org/wiki/Nitric_oxide_synthase_2_(inducible)
*  What is Nitric Oxide Synthase? (with pictures)
Nitric oxide synthase is a small molecule with a double covalent bond between nitrogen and oxygen atoms. In most cases, nitric ... Its production in epithelial cells is controlled by epithelial nitric oxide synthase (eNOS). Nitric oxide synthase is bound in ... Inducible nitric oxide synthase (iNOS) is employed by the body to stall the growth of cells in gastric epithelial, breast, and ... Neuronal nitric oxide synthase (nNOS) is continuously recycled to produce NO, as the NO is stable for mere seconds before being ...
https://www.wisegeek.com/what-is-nitric-oxide-synthase.htm
*  Structures: Nitric-oxide synthase, eukaryote (IPR012144) | InterPro | EMBL-EBI
Structures: Nitric-oxide synthase, eukaryote (IPR012144). PDBe. The Protein Data Bank (PDB) is a repository for the 3-D ...
http://www.ebi.ac.uk/interpro/entry/IPR012144/structures
*  nitric-oxide synthase, inducible Protein Superfamily Detail
Term: nitric-oxide synthase, inducible. ID: PIRSF000333 Mouse Protein Superfamily Annotations. Select one or more mouse PIRSF ...
http://www.informatics.jax.org/vocab/pirsf/PIRSF000333
*  Nitric-oxide synthase (NAD(P)H-dependent) - Wikipedia
Nitric-oxide synthase (NAD(P)H-dependent) (EC 1.14.13.165, nitric oxide synthetase, NO synthase) is an enzyme with systematic ... 2 nitric oxide + NAD(P)+ + 2 H2O Nitric-oxide synthase (NAD(P)H-dependent) binds heme (iron protoporphyrin IX) and ... "Bacterial flavodoxins support nitric oxide production by Bacillus subtilis nitric-oxide synthase". J. Biol. Chem. 282 (4): 2196 ... Nitric oxide synthase Wang, Z.Q.; Lawson, R.J.; Buddha, M.R.; Wei, C.C.; Crane, B.R.; Munro, A.W.; Stuehr, D.J. (2007). " ...
https://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NAD(P)H-dependent)
*  Proteins matched: Nitric oxide synthase, N-terminal (IPR004030) | InterPro | EMBL-EBI
Proteins matched: Nitric oxide synthase, N-terminal (IPR004030) This domain is found in the following proteins: Showing 1 to 20 ... Nitric oxide synthase, endothelial. Ovis aries (Sheep). Loading... P79290 Nitric oxide synthase, inducible. Sus scrofa (Pig). ... Nitric oxide synthase, brain. Homo sapiens (Human). Loading... P29476 3D Nitric oxide synthase, brain. Rattus norvegicus (Rat) ... Nitric oxide synthase, inducible. Mus musculus (Mouse). Loading... P35228 3D Nitric oxide synthase, inducible. Homo sapiens ( ...
http://www.ebi.ac.uk/interpro/entry/IPR004030/proteins-matched
*  Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation | PNAS
Nitric oxide is derived from L-arginine by isoforms of nitric-oxide synthase (NOS; EC 1.14.13.39): constitutive (cNOS; calcium- ... Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. J R Vane, J A Mitchell, I Appleton, A Tomlinson ... Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. J R Vane, J A Mitchell, I Appleton, A Tomlinson ... Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. J R Vane, J A Mitchell, I Appleton, A Tomlinson ...
http://www.pnas.org/content/91/6/2046
*  Uncoupling of Vascular Nitric Oxide Synthase Caused by Intermittent Hypoxia
... Mohammad Badran,1 Bisher Abuyassin,1 Saeid Golbidi ... U. Förstermann and T. Münzel, "Endothelial nitric oxide synthase in vascular disease: from marvel to menace," Circulation, vol ... A. Daiber, M. Oelze, S. Daub et al., "Vascular redox signaling, redox switches in endothelial nitric oxide synthase (eNOS ... S. Varadharaj, K. Porter, A. Pleister et al., "Endothelial nitric oxide synthase uncoupling: a novel pathway in OSA induced ...
https://www.hindawi.com/journals/omcl/2016/2354870/
*  Oxidative Stress, Nitric Oxide Synthase, and Superoxide Dismutase | Hypertension
Oxidative Stress, Nitric Oxide Synthase, and Superoxide Dismutase. A Matter of Imbalance Underlies Endothelial Dysfunction in ... Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest. ... oxidase and uncoupling of endothelial nitric oxide synthase (eNOS). There is also increased expression of endothelin-1 (ET-1), ... effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling. Circulation. 2006; 114: ...
http://hyper.ahajournals.org/content/51/1/31
*  Nitric Oxide Synthase Radiometric Assay Kit from Cayman Chemical
... ,The NOS assay kit measures NOS activity by monitoring the ... Mouse Anti-Thymidylate Synthase Monoclonal Antibody, Unconjugated, Clone 3A7.A11 from Abcam. 2. Mouse Anti-Bovine Complex V ( ... F1F0 ATP Synthase) Heart Mitochondria Monoclonal Antibody, Unconjugated, Clone 12F4AD8AF8 from MitoScience LLC. 3. Histone ...
http://www.bio-medicine.org/biology-products/Nitric-Oxide-Synthase-Radiometric-Assay-Kit-from-Cayman-Chemical-3566-1/
*  Endothelial Nitric Oxide Synthase Genotype and Ischemic Heart Disease | Circulation
Plasma nitric oxide concentrations and nitric oxide synthase gene polymorphisms in coronary artery disease. Clin Chem. 2000; 46 ... Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler ... Endothelial Nitric Oxide Synthase Genotype and Ischemic Heart Disease. Juan P. Casas, Leonelo E. Bautista, Steve E. Humphries ... Endothelial Nitric Oxide Synthase Genotype and Ischemic Heart Disease. Juan P. Casas, Leonelo E. Bautista, Steve E. Humphries ...
http://circ.ahajournals.org/content/109/11/1359
*  Nitric oxide synthase - definition of Nitric oxide synthase by The Free Dictionary
Nitric oxide synthase synonyms, Nitric oxide synthase pronunciation, Nitric oxide synthase translation, English dictionary ... definition of Nitric oxide synthase. n. See synthetase. n an enzyme that catalyses a process of synthesis ... Nitric oxide synthase - definition of Nitric oxide synthase by The Free Dictionary https://www.thefreedictionary.com/Nitric+ ... redirected from Nitric oxide synthase). Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.. Related to Nitric oxide ...
https://www.thefreedictionary.com/nitric+oxide+synthase
*  Frontiers | Nitric Oxide Synthases and Atrial Fibrillation | Physiology
Potential sources of oxidants include nitric oxide synthases, which normally produce nitric oxide in the heart. Two nitric ... which normally produce nitric oxide in the heart. Two nitric oxide synthase isoforms (1 and 3) are normally expressed in the ... During pathologies such as heart failure, there is induction of nitric oxide synthase 2 in multiple cell types in the ... During pathologies such as heart failure, there is induction of nitric oxide synthase 2 in multiple cell types in the ...
https://www.frontiersin.org/articles/10.3389/fphys.2012.00105/full
*  RCSB PDB - Protein Feature View - Nitric oxide synthase oxygenase - O34453 (NOSO BACSU)
2 L-arginine + 4 O2 + 3 reduced [flavodoxin] = 5 H+ + 4 H2O + 2 L-citrulline + 2 nitric oxide + 3 oxidized [flavodoxin] UniProt ...
https://www.rcsb.org/pdb/protein/O34453