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*  1LEI: The Kb Dna Sequence From The Hlv-Ltr Functions As An Allosteric Regulator Of Hiv Transcription
Nuclear Factor Nf-kappa-b P65 Subunit(Gene symbol: Rela). B. 1. Nuclear Factor Nf-kappa-b P50 Subunit(Gene symbol: Nfkb1) ... 3'NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT ...
https://www.ncbi.nlm.nih.gov/Structure/pdb/1LEI
*  Reactome | NFKB1(1-433) [nucleoplasm]
NFkB1 p50, Nuclear factor NF-kappa-B p50 subunit Locations in the PathwayBrowser Expand all ... NF-kappaB p50,p65,c-Rel dimer [nucleoplasm] (Homo sapiens) * NF-kappaB p50:c-Rel [nucleoplasm] (Homo sapiens) * NFKB1(1-433) [ ... p75NTR signals via NF-kB (Homo sapiens) * NF-kB is activated and signals survival (Homo sapiens) * NF-kB migrates to the ... NF-kappaB p50:p50 [nucleoplasm] (Homo sapiens) * NFKB1(1-433) [nucleoplasm] (Homo sapiens) ...
https://reactome.org/content/detail/R-HSA-177655
*  Staff Profile - Institute of Cellular Medicine - Newcastle University
Phosphorylation of serine 343 on the NF-kappa B P50 subunit is a pivotal regulator of inflammation. In: Hepatology: 59th Annual ... Regulation of NF-kappa B responses by epigenetic suppression of I kappa B alpha expression in HCT116 intestinal epithelial ... Elsharkawy AM, Oakley F, Lin F, Packham G, Mann DA, Mann J. The NF-κB p50:p50:HDAC-1 repressor complex orchestrates ... NF-KB1 (p50) protects against growth of hepatocellular carcinoma by suppressing ROS, inhibiting hepatic phospho-Stat3 and ...
https://www.ncl.ac.uk/icm/people/profile/jelenamann.html
*  Anti-Bcl3 antibody [Ham150-3.5] (ab15046) | Abcam
In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional ... Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. ... activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation. ...
http://www.abcam.com/bcl3-antibody-ham150-35-ab15046.html
*  Tissue expression of NFKB1 - Summary - The Human Protein Atlas
NF-kB1, NFkappaB, NFKB-p50, p105, p50) expression in human tissue. General cytoplasmic expression. Additional nuclear ... Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p50 subunit. A0A024RDJ4 [Target identity:100%; Query identity: ... Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p50 subunit. A0A024RDJ4 [Target identity:100%; Query identity: ... Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p50 subunit. ...
http://www.proteinatlas.org/ENSG00000109320-NFKB1/tissue
*  miR-16 reduced Ki-67 (a), MMP9 (b), and nuclear factor- | Open-i
NF-κB1) (c) expression in an in vivo mouse model using U87 glioma cells. miR-16, microRNA-16. ... NF-kappa B p50 Subunit/metabolism. *Neoplasm Invasiveness. *Neoplasm Transplantation. *RNA Interference ... fig06: miR-16 reduced Ki-67 (a), MMP9 (b), and nuclear factor-κB1 (NF-κB1) (c) expression in an in vivo mouse model using U87 ... fig06: miR-16 reduced Ki-67 (a), MMP9 (b), and nuclear factor-κB1 (NF-κB1) (c) expression in an in vivo mouse model using U87 ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4317940_cas0105-0265-f6&req=4
*  Rel homology domain, conserved site (IPR030492) | InterPro | EMBL-EBI
Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-kappa B in vitro.. Gene 145 197 ... It includes a conserved cysteine that seems to be essential for DNA-binding in p50 [PMID: 8056331]. ...
http://www.ebi.ac.uk/interpro/entry/IPR030492
*  A Dap12-Mediated Pathway Regulates Expression of Cc Chemokine Receptor 7 and Maturation of Human Dendritic Cells | JEM
1995) Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses. Cell 80:321-330, ... 1995) Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alphasignal-induced phosphorylation of I kappa B ... 1998) NF-kappa B and Rel proteinsevolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:225-260, pmid: ... NF-κB) or mutant (NF-κBmut) competing oligonucleotides. DNA-protein complexes were resolved by electrophoresis. The NF-κB- ...
http://jem.rupress.org/content/194/8/1111
*  NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1.
The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor. Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):8145 ... Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, Akira S. Transcription factors NF-IL6 and NF-kappa B ... Activation by NF-IL6 requires an intact NF-IL6 site and is modulated by the ratio of activator to inhibitor NF-IL6 isoforms ... Stein B, Baldwin AS, Jr, Ballard DW, Greene WC, Angel P, Herrlich P. Cross-coupling of the NF-kappa B p65 and Fos/Jun ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC359186/?lang=en-ca
*  Nfkbie - NF-kappa-B inhibitor epsilon - Mus musculus (Mouse) - Nfkbie gene & protein
Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes (By similarity). ... Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. ... Interacts with RELA, REL, NFKB1 nuclear factor NF-kappa-B p50 subunit and NFKB2 nuclear factor NF-kappa-B p52 subunit.By ... Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c- ...
https://www.uniprot.org/uniprot/O54910
*  anti-NFKB1 antibody | Rabbit anti-Human NFKB1-S907 Antibody-P19838.2
NF-kappabeta; DNA binding factor KBF1; DNA-binding factor KBF1; nuclear factor NF-kappa-B p50 subunit; nuclear factor kappa-B ... p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B. [Similar Products] ... Phospho-NFKB1-S907: p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B ... Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Nuclear factor NF-kappa-B p50 subunit. ...
https://www.mybiosource.com/prods/Antibody/NFKB1-S907/NFKB1/datasheet.php?products_id=128493
*  B-cell lymphoma 3 protein elisa and antibody
In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional ... In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional ... he nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] ... The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls t. >>> ...
https://www.mybiosource.com/protein_family.php?root=b-cell-lymphoma-3-protein
*  Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. - Semantic Scholar
The NFKB1 gene encodes the NF-kappaB p105/p50 isoforms. Genome-wide screens in IBD families show evidence for linkage on ... NF-kappaB) is a major transcription regulator of immune response, apoptosis and cell-growth control genes, and is upregulated ... The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its ... Relationship between NF-κB1 and NF-κBIA genetic polymorphisms and Crimean-Congo hemorrhagic fever.. Serdal Arslan, Aynur Engin ...
https://www.semanticscholar.org/paper/Functional-annotation-of-a-novel-NFKB1-promoter-for-Karban-Okazaki/500ef7cd5453566a719a05d6208f4a2fcc45a415
*  Impact on antibody responses of B-cell-restricted transgenic expression of a viral gene inhibiting activation of NF-κB and NFAT...
... an inhibitor of both NF-κB- and NFAT-mediated transcription. The A238L gene was selectively... ... Sha WC, Liou HC, Tuomanen EI, Baltimore D (1995) Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal ... Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha ... Granja AG, Perkins ND, Revilla Y (2008) A238L inhibits NF-ATc2, NF-kappa B, and c-Jun activation through a novel mechanism ...
https://link.springer.com/article/10.1007%2Fs00705-015-2419-x
*  Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors. | Molecular and...
Evidence is presented for a direct interaction between GR and the NF-kappa B subunits p65 and p50. In addition, we demonstrate ... synergistic NF-kappa B/AP-1 activity is largely unaffected. These data suggest that NF-kappa B, AP-1, and GR interact in a ... These data reveal a second mechanism by which NF-kappa B activity may be regulated by DEX. We also report that RU486 treatment ... This domain is also required for GR repression of AP-1. Surprisingly, while both AP-1 and NF-kappa B can be inhibited by ...
https://mcb.asm.org/content/15/2/943?ijkey=aea54cee7e6e126c0dc115a744e4fb0c44a6e263&keytype2=tf_ipsecsha
*  The MAPK Pathway Is a Predominant Regulator of HLA-A Expression in Esophageal and Gastric Cancer | The Journal of Immunology
... suppresses major histocompatibility complex class I gene expression through down-regulation of the p50 subunit of NF-kappa B. ... the constitutive proteasome subunit X, PSY, the constitutive proteasome subunit Y; PSZ, the constitutive proteasome subunit Z; ...
https://www.jimmunol.org/content/191/12/6261?ijkey=d9f6962873f804a0d4948fa2fba62492932838d2&keytype2=tf_ipsecsha
*  Low CCR7-Mediated Migration of Human Monocyte Derived Dendritic Cells in Response to Human Respiratory Syncytial Virus and...
ShaWCLiouHCTuomanenEIBaltimoreD 1995 Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune ... LPS is a strong NFκ-B and AP-1 dependent DC activator [66], [67]. Secondary stimulation of HRSV- and HMPV-infected MDDC with ... KrappmannDWegenerESunamiYEsenMThielA 2004 The IkappaB kinase complex and NF-kappaB act as master regulators of ... the NFκ-B/AP-1-dependent pro-inflammatory cytokines TNF-α, IL-1α and IL-6, at concentrations comparable to those induced by LPS ...
https://www.prolekare.cz/casopisy/plos-pathogens/2011-6/low-ccr7-mediated-migration-of-human-monocyte-derived-dendritic-cells-in-response-to-human-respiratory-syncytial-virus-and-human-metapneumovirus-46075
*  NF-κB Role and Potential Drug Targets in Gastrointestinal Cancer | SpringerLink
Urban MB, Baeuerle PA (1991) The role of the p50 and p65 subunits of NF-kappa B in the recognition of cognate sequences. New ... The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa ... Bargou RC, Leng C, Krappmann D, Emmerich F, Mapara MY, Bommert K, …, Dorken B (1996) High-level nuclear NF-kappa B and Oct-2 is ... Hewamana S, Alghazal S, Lin TT, Clement M, Jenkins C, Guzman ML, …, Pratt G (2008) The NF-κB subunit Rel A is associated with ...
https://link.springer.com/chapter/10.1007%2F978-981-10-6728-0_5
*  DiVA - Søkeresultat
... and changes in the expression of the p50 NF-kappa B subunit and the proinflammatory neuropeptides substance P (SP) and ... The elevated DNA-binding activity of the NF-kappa B/p50 homodimer and p50, as well as the neuronal expression of SP and CGRP, ... These effects may be mediated through the inhibition of NF-kappa B activation and may possibly involve the peripheral nervous ... Synthesis of these mediators is regulated by the transcription factor NF-kappa B, which is controlled by the ubiquitin ...
http://www.diva-portal.org/smash/resultList.jsf?dswid=-666&searchType=SUBJECT&language=no&onlyFullText=false&af=%5B%5D&aq=%5B%5B%7B%22categoryId%22%3A%2211651%22%7D%5D%5D
*  NF-kappaB Detection: Antibodies
... and nuclear factor NF-kappa-B p65 subunit.. Antibodies for NF-kappaB Detection. The NF-kappaB p50 and p65 antibodies are ... Alternate names for p50 include NFKB1, NFKB-p50, KBF1, EBP-1, DNA-binding factor KBF1, and nuclear factor NF-kappa-B p50 ... This subunit can form homodimers or heterodimers with other subunits; the most abundant NF-kappaB form consists of a p50-p65 ... NF-kappaB Detection. Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) is an ubiquitous transcription ...
http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Cytokines/NF_Kappa_B?sitex=10020:22372:US&PEBCL1=suphWgtkLuiwQDG0gCLXVRGQzV&PEBCL1_pses=ZG758E3CEF3953A99FA57F664ADFADF91C2C45283788F9F2473AD4AAA0A881D5B2BEB7F37271BB7FFB8076011C9558A77872DC88C2C19E4D62
*  Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: Novel insights into the regulation of Rev nuclear...
Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit. ... Huxford T, Huang DB, Malek S, Ghosh G: The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF- ... This is similar to I-κB, which interacts with and masks the NF-κB NLS domain, also preventing its nuclear import [35, 36]. To ...
https://rd.springer.com/article/10.1186/1742-4690-8-17
*  Sankar Ghosh - Wikipedia
265(5174): p. 956-9. Ghosh, S., et al., Cloning of the p50 DNA bin ding subunit of NF-kappa B: homology to rel and dorsal. Cell ... Ghosh, G., et al., Structure of NF-kappa B p50 homodimer bound to a kappa B site. Nature, 1995. 373(6512): p. 303-10. Thompson ... NF-kappa B and rel proteins in innate immunity. Adv Immunol, 1995. 58: p. 1-27. Kopp, E. and S. Ghosh, Inhibition of NF-kappa B ... 17(8): p. 4390-6. May, M.J. and S. Ghosh, Rel/NF-kappa B and I kappa B proteins: an overview. Semin Cancer Biol, 1997. 8(2): p ...
https://en.wikipedia.org/wiki/Sankar_Ghosh
*  NFRKB - Wikipedia
Urban MB, Schreck R, Baeuerle PA (1991). "NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit". EMBO J. 10 (7 ... Nuclear factor related to kappa-B-binding protein is a protein that in humans is encoded by the NFRKB gene. GRCh38: Ensembl ... Adams BS, Leung KY, Hanley EW, Nabel GJ (1992). "Cloning of R kappa B, a novel DNA-binding protein that recognizes the ... "Localization of the gene encoding R kappa B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25". Genomics ...
https://en.wikipedia.org/wiki/NFRKB
*  Bcl3抗体[Ham150-3.5]|Abcam中国|Anti-Bcl3抗体[Ham150-3.5]
In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional ... Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. ... activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation. ...
http://www.abcam.cn/bcl3-antibody-ham150-35-ab15046.html
*  Serial analysis of gene expression in the frontal cortex of patients with bipolar disorder | The British Journal of Psychiatry
Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by C-REL. Journal of Immunology, 150, ... encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation. EMBO Journal, 11, 195 -203. ... Deloukas, P. & van Loon, A. P. (1993) Genomic organization of the gene encoding the p65 subunit of NF-kappa B: multiple ... Liptay, S., Schmid, R. M., Nabel, E. G., et al (1994) Transcriptional regulation of NF-kappa B2: evidence for kappa B-mediated ...
http://bjp.rcpsych.org/content/178/41/s137