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*  What does nf-e2 transcription factor, p45 subunit mean?
Meaning of nf-e2 transcription factor, p45 subunit. What does nf-e2 transcription factor, p45 subunit mean? Information and ... translations of nf-e2 transcription factor, p45 subunit in the most comprehensive dictionary definitions resource on the web. ... Definition of nf-e2 transcription factor, p45 subunit in the Definitions.net dictionary. ... What does nf-e2 transcription factor, p45 subunit mean?. Definitions for nf-e2 transcription factor, p45 subunit. Here are all ...
https://www.definitions.net/definition/nf-e2%20transcription%20factor,%20p45%20subunit
*  Therapeutic Approach to Neurodegenerative Diseases by Medical Gases: Focusing on Redox Signaling and Related Antioxidant Enzymes
... type transcription factors [10]. NF-E2 is a heterodimeric protein which contains a large p45 and small p18 subunit [11]. ... Nuclear factor-erythroid 2 (NF-E2) related factor 2 (Nrf2) is an important transcription factor and is recognized as a major ... P. Moi, K. Chan, I. Asunis, A. Cao, and Y. W. Kan, "Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine ... In this paper, we highlight two major transcriptional regulation factors, nuclear factor-erythroid 2 (NF-E2) related factor 2 ( ...
https://www.hindawi.com/journals/omcl/2012/324256/
*  Nuclear Factor Erythroid Derived 2 Research Products: Novus Biologicals
Browse our Nuclear Factor Erythroid Derived 2 product catalog backed by our Guarantee+. ... Nuclear Factor Erythroid Derived 2 products available through Novus Biologicals. ... transcription factor NF-E2 45 kDa subunit. *Nuclear factor, erythroid-derived 2 45 kDa subunit ... nuclear factor (erythroid-derived 2), 45kD. *NF-E2. *p45 NF-E2. *nuclear factor (erythroid-derived 2), 45kDa ...
https://www.novusbio.com/common-name/nuclear-factor-erythroid-derived-2
*  SMART: WW domain annotation
Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II. ... By Far-Western blotting and yeast two-hybrid assay, we demonstrate that p45, the large subunit of NF-E2, is capable of binding ... NF-E2 is an erythroid-specific transcription factor required for expression of several erythroid-specific genes. ... Solution structure of the first WW domain from the mouse transcription elongation regulator 1, transcription factor CA150. ...
http://smart.embl.de/smart/do_annotation.pl?DOMAIN=WW&
*  Search Articles | University of Toronto Libraries
NF-E2 Transcription Factor, p45 Subunit - metabolism , Histone-Lysine N-Methyltransferase - genetics , Erythroid Cells - ... Basic Helix-Loop-Helix Transcription Factors - genetics , Core Binding Factor Alpha 2 Subunit - metabolism , Jurkat Cells , ... Risk factors , Genetics , Transgenic animals , Rodents , Stem cells , Flow cytometry , NF-B protein , Transformation , Data ... 1. Full Text Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages ...
https://query.library.utoronto.ca/index.php/search/q?kw=Author:Perez-Iratxeta,%20C
*  Recombinant Human NFE2 293 Cell Lysate NFE2-3855HCL - Creative BioMart
Recombinant Human NFE2 293 Cell Lysate can be used for research. ... Purified Recombinant Human NFE2 293 Cell Lysate from Creative ... transcription factor NF-E2 45 kDa subunit; NF E2; p45 NF-E2; leucine zipper protein NF-E2; nuclear factor, erythroid-derived 2 ... NFE2. Synonyms:. NFE2; nuclear factor (erythroid-derived 2), 45kDa; nuclear factor (erythroid derived 2), 45kD; ... NFE2-3855HCL. Description:. Antigen standard for nuclear factor (erythroid-derived 2), 45kDa (NFE2), transcript variant 1 is a ...
https://www.creativebiomart.net/description_405521_318.htm
*  High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated...
Two factors important in its detoxification are UDP-glucuronosyltransferase (UDP-GT), an ARE-regulated phase-II drug- ... transcription factor family, has been implicated as a key molecule involved in antioxidant-responsive element (ARE)-mediated ... Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene ... Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene.. *Jawed Alam, Daniel Stewart, ...
https://www.semanticscholar.org/paper/High-sensitivity-of-Nrf2-knockout-mice-to-with-of-Enomoto-Itoh/d30a88208b063b8239b854f66cedf1c4e06da183
*  KIX domain - Wikipedia
... of interactions between transactivation domain 1 of the p65 subunit of NF-κB and transcription regulatory factors". Nucleic ... NFE2 (NF-E2 p45) RELA (NF-κB p65) SREBP STAT1 TCF3 (E2A) TP53 (p53) YY1 Yeast proteins: Gal4p Gcn4 Pdr1 Pdr3 Oaf1 Viral ... The coactivators CBP (CREBBP) and P300 (EP300) are recruited to DNA-bound transcription factors to activate transcription. ... Goto, N. K.; Zor, T; Martinez-Yamout, M; Dyson, H. J.; Wright, P. E. (2002). "Cooperativity in transcription factor binding to ...
https://en.wikipedia.org/wiki/KIX_domain
*  Acetylation of Nrf2 by p300/CBP Augments Promoter-Specific DNA Binding of Nrf2 during the Antioxidant Response
The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and ... modifier subunit (GCLM) and catalytic subunit (GCLC) (2, 37, 40, 60). A growing body of evidence has established the Nrf2- ... Since acetylation of transcription factors is a reversible process that fine tunes transcription, it is conceivable that the ... Nrf2 is the critical transcription factor responsible for ARE-dependent transcription. We and others have previously ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2682049/
*  List of MeSH codes (D12.776.930) - Wikipedia
... nf-e2 transcription factor, p45 subunit MeSH D12.776.930.155.200.100 -- core binding factor alpha 1 subunit MeSH D12.776. ... mafk transcription factor MeSH D12.776.930.316.750.770 -- nf-e2 transcription factor, p45 subunit MeSH D12.776.930.323.500.500 ... core binding factor alpha 3 subunit MeSH D12.776.930.316.750.750 -- maf transcription factors, small MeSH D12.776.930.316. ... transcription factor brn-3b MeSH D12.776.930.632.625.875 -- transcription factor brn-3c MeSH D12.776.930.635.600.100 -- ets- ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.930)
*  The Cap 'n' Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and...
In the Nrf2(−/−) mice, the Gsta3 subunit was induced in the small intestine by BHA, OPZ, and CMRN, and the Gsta4 subunit was ... The Cap 'n' Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and ... The Cap 'n' Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and ... The Cap 'n' Collar Basic Leucine Zipper Transcription Factor Nrf2 (NF-E2 p45-related Factor 2) Controls Both Constitutive and ...
http://cancerres.aacrjournals.org/content/61/8/3299?ijkey=f6d9b50c791d61d3c3f5a1c64da58b5283ba5d6b&keytype2=tf_ipsecsha
*  Novel Hematopoietic Target Genes in the NRF2-Mediated Transcriptional Pathway
... analysis of putative heme regulatory motifs in the p45 NF-E2 transcription factor," Antioxidants and Redox Signaling, vol. 8, ... Made of four subunits as a tetramer, adult Hb consists of two alpha-globin and two beta-globin chains, each chain consisting of ... "Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network," Proceedings of ... R. A. Shivdasani and S. H. Orkin, "Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2," ...
https://www.hindawi.com/journals/omcl/2013/120305/
*  Identification of Bach2 as a B‐cell‐specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy...
... specific transcription factor NFE2 is a heterodimer formed between the erythroid‐ and megakaryocyte‐specific bZip protein, p45 ... The ubiquitous subunit of erythroid transcription factor NFE2 is a small basic‐leucine zipper protein related to the v‐maf ... Moi P, Chan K, Asunis I, Cao A and Kan YW (1994) Isolation of NFE2‐related factor 2 (Nrf2), an NFE2‐like basic leucine zipper ... Regulation of transcription by dimerization of erythroid factor NFE2 p45 with small Maf proteins. Nature, 367, 568-572. ...
http://emboj.embopress.org/content/17/19/5734
*  BRF2 Gene - GeneCards | BRF2 Protein | BRF2 Antibody
RNA Polymerase III Transcription Initiation Factor Subunit, including: function, proteins, disorders, pathways, orthologs, and ... BRF2, RNA Polymerase III Transcription Initiation Factor Subunit 2 3 5 * BRF2, Subunit Of RNA Polymerase III Transcription ... NF-E2 p45. See All at QIAGEN. Regulatory Element Products. * SwitchGear BRF2 promoter sequence ... transcription factor activity, RNA polymerase III transcription factor binding. IMP. 26638071. GO:0001032. RNA polymerase III ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=BRF2
*  ZNF326 Gene - GeneCards | ZN326 Protein | ZN326 Antibody
Binding Sites for Transcription Factors within promoters. ENSR00000009651. 688. 2401. PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ... NF-E2 p45. *NF-E2. *ER-alpha. *FOXD3. *Msx-1. See All at QIAGEN ... DBIRD complex subunit ZNF326 Protein Accession:. Q5BKZ1. ... Transcription Factor Binding Sites within enhancer. Gene Targets for Enhancer. GH01H089900. 2. FANTOM5 Ensembl ENCODE dbSUPER ... Transcription Factor Targets and HOMER Transcription for ZNF326 Gene ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=ZNF326
*  NFE2 - Transcription factor NF-E2 45 kDa subunit - Homo sapiens (Human) - NFE2 gene & protein
Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin ... Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C ... Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. ... "Sumoylation of p45/NF-E2: nuclear positioning and transcriptional activation of the mammalian beta-like globin gene locus.". ...
http://www.uniprot.org/uniprot/Q16621
*  Stuart Orkin, MD | Boston Children's Hospital
The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf ... cDNA cloning of murine Nrf 2 gene, coding for a p45 NF-E2 related transcription factor. Biochem Biophys Res Commun. 1995 Apr 06 ... Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus. Proc Natl ... Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in ...
http://specialists.childrenshospital.org/directory/physicians/o/stuart-orkin
*  Cancers | Free Full-Text | BRCA1 and Oxidative Stress | HTML
BRCA1 augments transcription by the NF-κB transcription factor by binding to the Rel domain of the p65/RelA subunit. J. Biol. ... Miao, W.; Hu, L.; Scrivens, P.J.; Batist, G. Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the ... Table 1. Transcription factors that bind to BRCA1.. Transcription factor. Region in BRCA1 (aa). Assays. References. ... NF-κB) and stimulate the tumor necrosis factor-α (TNF-α) and the interleukin-1β (IL-1β)-induced transcription of NF-κB-target ...
http://www.mdpi.com/2072-6694/6/2/771/htm
*  May 2019 - biobender.com
The NF-E2 theme binds a heteromeric complicated comprising an hematopoietic-specific 45-kDa subunit (p45 NF-E2) (23, 24), a ... The overall transcription factor complicated TFIID, which binds towards the TATA container, and an linked component TFIIB, have ... NF-E2 missing this activation domains within an NF-E2 null cell series does not support enhancer-dependent transcription in ... Protein-protein interaction research reveal that domains of p45 NF-E2 binds particularly to an element from the transcription ...
http://biobender.com/2019/05/
*  UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra‐embryonic cells | The EMBO...
... binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NFE2. ... In this report, we describe the molecular cloning of a novel transcription factor termed UTF1. This factor was isolated using a ... kDa subunit is a homolog of yeast AC19 subunit of RNA polymerase I and III. J Biol Chem, 271, 32881-32885. ... Rosner MH, Vigano MA, Ozato K, Timmons PM, Poirier F, Rigby PWJ and Staudt LM (1990) A POU‐domain transcription factor in early ...
http://emboj.embopress.org/content/17/7/2019
*  UNIVERSITA' DEGLI STUDI DI CATANIA
The Cap‗n'Collar basic leucine zipper transcription factor Nrf2 (NFE2 p45-related factor 2) controls both constitutive and ... Moi, P., Chan, K., Asunis, I., Cao, A., and Kan, Y. W. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine ... Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated by cellular redox. J ... Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its a subunit. J ...
http://spotidoc.com/doc/21737/universita%E2%80%99-degli-studi-di-catania
*  Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1) | SpringerLink
It has been clearly demonstrated that the nuclear factor-E2 p45-related factor 2 (Nrf2), the key transcriptional factor of ... Hayashi A, Suzuki H, Itoh K, Yamamoto M, Sugiyama Y (2003) Transcription factor Nrf2 is required for the constitutive and ... We appreciate the support of research grants (OTKA AT 048729, NF 61822), which allowed us to compile this review. László ... Similar to MRP1, another oxidative stress-sensitive gene product, the heavy subunit of γ-glutamylcysteine synthetase (γ-GCSh), ...
https://link.springer.com/article/10.1007%2Fs00424-006-0160-8
*  Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma | JEM
The transcription factor NF-E2-related factor 2 (Nrf2) is important for maintaining cellular homeostasis, and when cells are ... Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas. Head Neck. 28: ... glutamate-cysteine ligase, catalytic subunit. GCLM. glutamate-cysteine ligase, modifier subunit. HCC. hepatocellular carcinoma ... Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor ...
http://jem.rupress.org/content/213/5/859
*  Nitric Oxide and Mitochondrial Signaling | Arteriosclerosis, Thrombosis, and Vascular Biology
The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and ... Cheung PC, Salt IP, Davies SP, Hardie DG, Carling D. Characterization of AMP-activated protein kinase gamma-subunit isoforms ... Activation of NF-kappaB nuclear transcription factor by flow in human endothelial cells. Biochim Biophys Acta. 2003; 1642: 33- ... Among these, regulation of NF-E2 related factor (Nrf-2) (reviewed by Nguyen et al67) may be of relevance because of its ...
http://atvb.ahajournals.org/content/27/12/2524.full
*  SEURAT-1 liver gold reference compounds: a mechanism-based review | SpringerLink
Miao W, Hu L, Scrivens PJ, Batist G (2005) Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl ... Varga T, Czimmerer Z, Nagy L (2011) PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid ... Yang SY, Schulz H (1983) The large subunit of the fatty acid oxidation complex from Escherichia coli is a multifunctional ... Higgins LG, Hayes JD (2011) The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental ...
https://link.springer.com/article/10.1007/s00204-014-1410-8?sa_campaign=email/event/articleAuthor/onlineFirst