Thus, the membrane protein SV apparently contributes to myosin II assembly during cell spreading by modulating myosin II ... The L-MLCK- and myosin-binding site in SV, SV1-171, rearranges and co-localizes with mono- and di-phosphorylated myosin light ... and myosin II-dependent mechanism. Overexpression of SV reduces the rate of cell spreading, and RNAi-mediated knockdown of ... cortical bundles of F-actin and activated myosin II during early cell spreading. The effects of SV are reversed by inhibition ...
N2 - The actomyosin molecular motor, the motor composed of myosin II and actin filament, is responsible for muscle contraction ... AB - The actomyosin molecular motor, the motor composed of myosin II and actin filament, is responsible for muscle contraction ... The actomyosin molecular motor, the motor composed of myosin II and actin filament, is responsible for muscle contraction, ... abstract = "The actomyosin molecular motor, the motor composed of myosin II and actin filament, is responsible for muscle ...
Blebbistatin, a Myosin II Inhibitor, Blocks Melanosome Aggregation But Not Dispersion in Fish Retinal Pigment Epithelial (RPE) ... "Blebbistatin, a Myosin II Inhibitor, Blocks Melanosome Aggregation But Not Dispersion in Fish Retinal Pigment Epithelial (RPE) ...
T2 - Conformational changes induced by calmodulin-binding peptides from myosin light chain kinase and protein kinase II ... Conformational changes induced by calmodulin-binding peptides from myosin light chain kinase and protein kinase II. In: ... Conformational changes induced by calmodulin-binding peptides from myosin light chain kinase and protein kinase II. ... Conformational changes induced by calmodulin-binding peptides from myosin light chain kinase and protein kinase II. ...
... also called type I and type II fibers, respectively). Small numbers of other fiber types, such as superfast fibers and true- ... Contractile properties, fiber types, and myosin isoforms in fast and slow muscles of hyperactive Japanese waltzing mice. Exp. ... 4 A, peak Δ[CaTrop] shows a large difference between the two fiber types: 86 µM for slow-twitch fibers and 227 µM for fast- ... Δ[CaSlowB] is also very different in the two fiber types, with values of 9 and 146 µM, respectively, at t = 50 ms. This ...
In addition, irradiated wild-type mice treated with two distinct MLCK enzymatic inhibitors, ML-7 and PIK (peptide inhibitor of ... In addition, irradiated wild-type mice treated with two distinct MLCK enzymatic inhibitors, ML-7 and PIK (peptide inhibitor of ... In addition, irradiated wild-type mice treated with two distinct MLCK enzymatic inhibitors, ML-7 and PIK (peptide inhibitor of ... In addition, irradiated wild-type mice treated with two distinct MLCK enzymatic inhibitors, ML-7 and PIK (peptide inhibitor of ...
Opposite regulations by androgenic and thyroid hormones of V1 myosin expression in the two types of rabbit striated muscle: ... Publication type, MeSH terms, Substances. Publication type. *Research Support, Non-U.S. Govt ... The finding that V1 cardiac myosin is expressed in masticatory skeletal muscles of the rabbit provided a unique opportunity for ...
cDNA FLJ78685, highly similar to Homo sapiens myosin binding protein C, slow type (MYBPC1), transcript variant 2, mRNAImported ... tr,A8KAB1,A8KAB1_HUMAN cDNA FLJ78685, highly similar to Homo sapiens myosin binding protein C, slow type (MYBPC1), transcript ... cDNA FLJ78685, highly similar to Homo sapiens myosin binding protein C, slow type (MYBPC1), transcript variant 2, mRNA. ... It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have ...
The S. cerevisiae wild-type myosin type II (Myo1p) localizes to the bud-neck during cell division (Bi et al. 1998); the Myo1p ... Novel Interactome of Saccharomyces cerevisiae Myosin Type II Identified by a Modified Integrated Membrane Yeast Two-Hybrid ( ... Novel Interactome of Saccharomyces cerevisiae Myosin Type II Identified by a Modified Integrated Membrane Yeast Two-Hybrid ( ... Novel Interactome of Saccharomyces cerevisiae Myosin Type II Identified by a Modified Integrated Membrane Yeast Two-Hybrid ( ...
... pombe also uses type II myosin to execute cell division.. Mammalian type II myosin is a hexamer, composed of two copies each of ... Type II myosin heavy chains known to date carry two IQ motifs, agreeing with the hexameric structure of myosin II. However, we ... Thus, we suspect that the type II myosin heavy chain of S. pombe may interact with only one myosin light chain. Interestingly, ... 1991) The yeast type II myosin heavy chain: analysis of its predicted polypeptide sequence. J Muscle Res Cell Motil 12:61-68, ...
van Leeuwen, H, Elliott, G and OHare, P (2002) Evidence of a role for nonmuscle myosin II in herpes simplex virus type 1 ... Evidence of a role for nonmuscle myosin II in herpes simplex virus type 1 egress ...
Using RT-PCR and fluorescent in situ hybridization, we demonstrated that UCN II and type-2 CRH receptor (CRH-R2) mRNAs were ... Urocortin II is expressed in human pregnant myometrial cells and regulates myosin light chain phosphorylation: Potential role ... 2004) Urocortin II is expressed in human pregnant myometrial cells and regulates myosin light chain phosphorylation: Potential ... In this study we investigated the expression of urocortin II (UCN II) in human myometrium and its ability to phosphorylate ...
Publication types, MeSH terms, Substance, Grant support. Publication types. *Research Support, N.I.H., Extramural ... Determinants of myosin II cortical localization during cytokinesis.. Uehara R1, Goshima G, Mabuchi I, Vale RD, Spudich JA, ... Myosin II is an essential component of the contractile ring that divides the cell during cytokinesis. Previous work showed that ... In 20% of cells some transient bursts of myosin filament formation were observed. However, in 80% of cells no myosin filament ...
Histocompatibility Antigens Class II / metabolism* * Male * Mice * Microfluidic Analytical Techniques * Myosin Type II / ... We further highlight that myosin IIA enrichment at the cell front requires the MHC class II-associated invariant chain (Ii). ... Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells Nat Commun. 2015 Jun 25;6 ... We propose that the requirement for myosin II in both cell migration and specific cell functions may provide a general ...
1 Institute of Physiology II, University of Münster, Münster, Germany. [email protected] ... Publication types * Research Support, Non-U.S. Govt MeSH terms * Calcium / metabolism ... Real-time monitoring of cell elasticity reveals oscillating myosin activity Biophys J. 2010 Dec 1;99(11):3639-46. doi: 10.1016/ ... In conclusion, the collective activities of the myosin motor proteins define overall mechanical cell dynamics, reflecting ...
The level of myosin II phosphorylation is determined by activities of myosin light chain kinase and myosin phosphatase (MP). MP ... Phosphorylation of myosin II plays an important role in many cell functions, including smooth muscle contraction. ... Myosin Type II / chemistry, genetics, metabolism*. Myosin-Light-Chain Phosphatase / chemistry, genetics, metabolism*. ... The level of myosin II phosphorylation is determined by activities of myosin light chain kinase and myosin phosphatase (MP). MP ...
Type II myosin is the major constituent of sarcomeres. In the neck region of this protein, there are binding sites for a pair ... Myosin light chain kinase and myosin phosphorylation effect frequency-dependent potentiation of skeletal muscle contraction. ... Among the several paralogs of the myosin regulatory light chain in vertebrates (5), myosin regulatory light chain 2, ... Myoinformatics report: myosin regulatory light chain paralogs in the human genome. J. Muscle Res. Cell Motil. 27:69-74. View ...
Two types of mRNA encoding myosin regulatory light chain in carp fast skeletal muscle differ in their 3 non-coding regions and ... Two types of mRNA encoding myosin regulatory light chain in carp fast skeletal muscle differ in their 3 non-coding regions and ... Two types of mRNA encoding myosin regulatory light chain in carp fast skeletal muscle differ in their 3 non-coding regions and ... title = "Two types of mRNA encoding myosin regulatory light chain in carp fast skeletal muscle differ in their 3 non-coding ...
Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus- ... Publication types, MeSH terms, Substances, Grant support. Publication types. *Research Support, N.I.H., Extramural ... its role in type 2 diabetes mellitus (T2DM)-associated ESRD is unclear. ...
Here we report a phylogenetic analysis of DNA sequences from the myosin heavy chain type II (myosin II) gene from a large set ... Our study demonstrates, both for the myosin II data set alone and for a combined SSU + myosin II data set, that Platyhelminthes ... A phylogenetic analysis of myosin heavy chain type II sequences corroborates that Acoela and Nemertodermatida are basal ... A phylogenetic analysis of myosin heavy chain type II sequences corroborates that Acoela and Nemertodermatida are basal ...
Schematic drawings of wild-type myosin II and green fluorescent protein (GFP)-RLC-myosin rod. Wild-type myosin II is a ... GFP-RLC-myosin rod binds RLC but does not interact with actin. (A) (Left) Wild-type myosin II and GFP-RLC-myosin rod were ... GFP-myosin II and GFP-RLC-myosin rod, but not GFP-3xASP myosin II, are localized to the cleavage furrows. (A and B) Time-lapse ... Conventional myosin II is a hexameric molecule composed of two heavy chains, two essential light chains (ELCs), and two ...
We observed two pools of Slt2p, the final Mitogen Activated Protein Kinase (MAPK) of the PKC1 CWIP; one pool that is up ... a chitin synthase II null mutant that also activates the PKC1 CWIP and exhibits cytokinesis defects very similar to myo1Δ, ... Deletion of myosin type II (myo1Δ) in Saccharomyces cerevisiae results in a cell that has defective cytokinesis. To survive ... Deletion of myosin type II (myo1Δ) in Saccharomyces cerevisiae results in a cell that has defective cytokinesis. To survive ...
Myosin II (also known as conventional myosin) is the myosin type responsible for producing muscle contraction in muscle cells. ... holding the two heavy chains together (imagine two snakes wrapped around each other, as in a caduceus). Thus, myosin II has two ... Myosin Isoforms MBInfo - The Myosin Powerstroke Myosin Video A video of a moving myosin motor protein. Myosins at the US ... Myosin VI is thought to transport endocytic vesicles into the cell. Myosin VII is an unconventional myosin with two FERM ...
Role of the two type II myosins, Myo2 and Myp2, in cytokinetic actomyosin ring formation and function in fission yeast. ... Unlike most organisms in which its composition has been investigated, the fission yeast CAR contains two type II myosins ... II, and V. Unlike fission yeast, both contained a single type II myosin gene that, on the basis of its tail structure, was more ... To determine whether the presence of two type II myosinswas a feature of cytokinesis in other fungi that divide by septation, ...
Myosin Type II); SRQ9WWM084 (latrunculin A). ... On the other hand, inhibition of myosin II activity by (-)- ... Comparative fluorescence microscopy of the distribution of actin filaments and that of myosin II revealed that the inhibition ... while the myosin II activity is involved in the maintenance of the dynamic turnover of actin in lamellipodium.. ... relative importance of the forces generated by actin polymerization and myosin II in this process remains elusive. We have ...