Loading...
*  Role of ischaemic postconditioning regulates endoplasmic reticulum stress in prevention of myocardial reperfusion injury | Heart
Role of ischaemic postconditioning regulates endoplasmic reticulum stress in prevention of myocardial reperfusion injury ... Role of ischaemic postconditioning regulates endoplasmic reticulum stress in prevention of myocardial reperfusion injury ... Left ventricular myocardial was separated and cut to five slice. After experiment, the myocardial was used for myocardial ... Acute myocardial infarction (AMI) is one of the leading causes of death in the world, demands early and complete reperfusion in ...
http://heart.bmj.com/content/97/Suppl_3/A127.3
*  1 The cathepsin-L inhibitor CAA0225 protects against myocardial ischaemia-reperfusion injury | Heart
Ischaemia-reperfusion (IR) injury contributes to the cardiac damage following myocardial infarction and paradoxically reduces ... 1 The cathepsin-L inhibitor CAA0225 protects against myocardial ischaemia-reperfusion injury ... 1 The cathepsin-L inhibitor CAA0225 protects against myocardial ischaemia-reperfusion injury ... Ischaemia-reperfusion injury was induced by 45 min temporary coronary artery ligation and CAA0225 was given by intra-venous ...
http://heart.bmj.com/content/101/Suppl_6/A1.1
*  Myocardial Reperfusion Injury Summary Report | CureHunter
Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) ... Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary ... Myocardial Ischemic Reperfusion Injury; Injuries, Myocardial Reperfusion; Myocardial Reperfusion Injuries; Reperfusion Injuries ... Myocardial Reperfusion Injury. Subscribe to New Research on Myocardial Reperfusion Injury Damage to the MYOCARDIUM resulting ...
http://www.curehunter.com/public/keywordSummaryD015428-Myocardial-Reperfusion-Injury.do
*  Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion
"Sivelestat reduces myocardial ischemia and reperfusion injury in rat hearts even when administered after onset of myocardial ... "Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion," ... Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion. Sverre E. Aune,1 Steve T. Yeh, ... B. R. Lucchesi, "Myocardial ischemia, reperfusion and free radical injury," American Journal of Cardiology, vol. 65, no. 19, pp ...
https://www.hindawi.com/journals/omcl/2013/279847/ref/
*  Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury - Full Text View - ClinicalTrials.gov
Myocardial Ischemia. Reperfusion Injury. Myocardial Reperfusion Injury. Pathologic Processes. Necrosis. Heart Diseases. ... Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury. The safety and scientific validity of this study is the ... Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury) trial. J Am Coll Cardiol. 2009 Feb 24;53(8):720-9. doi: ... the Efficacy of FX06 in the prevention of myocardial reperfusion injury trial. EuroIntervention. 2010 Apr;5(8):946-52. doi: ...
https://clinicaltrials.gov/ct2/show/NCT00326976
*  Vitamin D Receptor Activation Protects against Myocardial Reperfusion Injury through Inhibition of Apoptosis and Modulation of...
... in ischemia/reperfusion-induced myocardial injury and to investigate the underlying mechanisms involved. Results: The ... endogenous VDR expression was detected in the mouse heart, and myocardial i ... Aims: To determine the roles of vitamin D receptor (VDR) in ischemia/reperfusion-induced myocardial injury and to investigate ... Vitamin D Receptor Activation Protects against Myocardial Reperfusion Injury through Inhibition of Apoptosis and Modulation of ...
http://www.biomedsearch.com/nih/Vitamin-D-Receptor-Activation-Protects/25365634.html
*  Beneficial effects of sevoflurane and desflurane against myocardial reperfusion injury after cardioplegic arrest | Springer for...
Purpose To determine whether sevoflurane or desflurane offer additional protective effects against myocardial reperfusion ... injury after protecting the heart against the ischemic injury by cardioplegic... ... Enflurane and isoflurane, but not halothane, protect against myocardial reperfusion injury after cardioplegic arrest with HTK ... Effects of halothane, enflurane, isoflurane, sevoflurane and desflurane on myocardial reperfusion injury in the isolated rat ...
https://rd.springer.com/article/10.1007/BF03013206
*  JCI - Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Lethal myocardial reperfusion injury attenuates the full benefits of myocardial reperfusion in terms of MI size reduction and ... This figure illustrates the individual contributions of acute myocardial ischemic injury and myocardial reperfusion injury to ... a phenomenon known as myocardial reperfusion injury (1-3). Although the process of myocardial reperfusion continues to improve ... there is still no effective therapy for preventing myocardial reperfusion injury. In this respect, myocardial reperfusion ...
https://www.jci.org/articles/view/62874
*  Myocardial reperfusion injury: looking beyond primary PCI - UCL Discovery
Myocardial reperfusion injury, ST-elevation myocardial infarction, Primary percutaneous coronary intervention, Cardioprotection ... Myocardial reperfusion injury: looking beyond primary PCI. EUROPEAN HEART JOURNAL , 34 (23) 1714-+. 10.1093/eurheartj/eht090. ...
http://discovery.ucl.ac.uk/1389522/
*  JCI - Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury
Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury. Chengjun Hu,1,2 Yihao Tian ... including myocardial ischemia-reperfusion injury (IRI), but the molecular basis of UPS impairment remains poorly understood. ... particularly in response to myocardial ischemia/reperfusion injury, thereby suggesting that this may be a new avenue for ... Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury ...
https://www.jci.org/articles/view/98287
*  Combination of necroptosis and apoptosis inhibition enhances cardioprotection against myocardial ischemia-reperfusion injury |...
We investigated whether necroptosis is involved in myocardial ischemia-reperfusion... ... We investigated whether necroptosis is involved in myocardial ischemia-reperfusion injury in isolated guinea pig hearts and, if ... Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury. Br J Pharmacol. ... Necroptosis is involved in myocardial ischemia-reperfusion injury, and simultaneous inhibition of necroptosis and apoptosis ...
https://link.springer.com/article/10.1007%2Fs00540-013-1716-3
*  Frontiers | Ginsenoside Rg1 Ameliorates Rat Myocardial Ischemia-Reperfusion Injury by Modulating Energy Metabolism Pathways |...
The present study was designed to investigate the protective effect of Rg1 on heart ischemia and reperfusion (I/R) injury, with ... These results indicated that Rg1 had protective potential against I/R-induced myocardial injury, which may be related to ... These results indicated that Rg1 had protective potential against I/R-induced myocardial injury, which may be related to ... Rg1 prevented I/R-elicited insults in myocardium, including myocardial infarction and apoptosis, decreased myocardial blood ...
https://www.frontiersin.org/articles/10.3389/fphys.2018.00078/full
*  Increased myocardial ischemia-reperfusion injury in renal failure involves cardiac adiponectin signal deficiency. | Sigma...
Increased myocardial ischemia-reperfusion injury in renal failure involves cardiac adiponectin signal deficiency.. [Yanbin Song ... The present study was designed to determine the role of APN in myocardial ischemia-reperfusion (MI/R) injury in mice with renal ... The present study demonstrates that renal dysfunction increases cardiac susceptibility to ischemic-reperfusion injury, which is ... Moreover, SN increased myocardial NO metabolites, superoxide, and their cytotoxic reaction product peroxynitrite, upregulated ...
https://www.sigmaaldrich.com/catalog/papers/24595307
*  Protective Effects of L-Malate against Myocardial Ischemia/Reperfusion Injury in Rats
... Shiao Ding, Yang Yang, and Ju Mei ... Shiao Ding, Yang Yang, and Ju Mei, "Protective Effects of L-Malate against Myocardial Ischemia/Reperfusion Injury in Rats," ...
https://www.hindawi.com/journals/ecam/2016/3803657/cta/
*  Management of Myocardial Reperfusion Injury 2012th Edition | PDF Free Download
Much has been written about reperfusion injury in the past decade but unfortunately the information has been generally ... Management of Myocardial Reperfusion Injury will tackle these issues in a modern and systematic way and the information will be ... Much has been written about reperfusion injury in the past decade but unfortunately the information has been generally ... The pathophysiology and molecular mechanisms of reperfusion injury are complex and, regarding diagnosis, individual diagnostic ...
http://ebook-dl.com/book/79416
*  IJMS | Free Full-Text | Combined Therapy with SS31 and Mitochondria Mitigates Myocardial Ischemia-Reperfusion Injury in Rats
... injury contributes to adverse cardiac outcomes after myocardial ischemia, cardiac surgery, or circulatory arrest. In this study ... therapy to protect heart cells from myocardial IR injury. Adult male SD rats (n = 8/each group) were randomized: group 1 (sham- ... operated control), group 2 (IR, 30-min ischemia/72 h reperfusion), group 3 (IR-SS31 (2 mg intra-peritoneal injection at 30 min/ ... demonstrates that the combined SS31-Mito therapy is superior to either therapy alone for protecting myocardium from IR injury ...
https://www.mdpi.com/1422-0067/19/9/2782
*  Postconditioning A new link in nature's armor against myocardial ischemia-reperfusion injury | SpringerLink
Reperfusion injury is a complex process involving several cell types (endothelial cells, neutrophils, and cardiomyocytes), ... Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion. ... Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat. Circulation ... Ischemic postconditioning during reperfusion fails to protect against lethal myocardial ischemia-reperfusion injury in pigs. ...
https://link.springer.com/article/10.1007%2Fs00395-005-0523-x
*  Imbalance Between Tissue Inhibitor of Metalloproteinase-4 and Matrix Metalloproteinases During Acute Myocardial Ischemia...
Tissue Inhibitor of Metalloproteinase-4 and Matrix Metalloproteinases During Acute Myocardial Ischemia-Reperfusion Injury. ... Tissue Inhibitor of Metalloproteinase-4 and Matrix Metalloproteinases During Acute Myocardial Ischemia-Reperfusion Injury ... Tissue Inhibitor of Metalloproteinase-4 and Matrix Metalloproteinases During Acute Myocardial Ischemia-Reperfusion Injury ... Tissue Inhibitor of Metalloproteinase-4 and Matrix Metalloproteinases During Acute Myocardial Ischemia-Reperfusion Injury ...
http://circ.ahajournals.org/content/early/2003/04/21/01.CIR.0000065603.09430.58
*  Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury. - Semantic Scholar
Muscular exercise is a countermeasure to protect against IR-induced cardiac injury in both young and old animals. Specifically ... Of the known putative cardioprotective mechanisms, current evidence suggests that elevated myocardial levels of antioxidants ... induction of myocardial heat shock proteins, improved cardiac antioxidant capacity, and/or elevation of ATP-sensitive potassium ... injury is a major contributor to the morbidity and mortality associated with coronary artery disease. ...
https://www.semanticscholar.org/paper/Exercise-induced-cardioprotection-against-injury.-Powers-Quindry/7467eaac812d7683b8802d1777b20178510732b2
*  Increase in experimental infarct size with digoxin in a canine model of myocardial ischemia-reperfusion injury.
These data suggest that an exacerbation or enhancement of myocardial ischemia-reperfusion injury may occur in the presence of ... followed by 6 hours of reperfusion. Anatomic myocardial infarct size, expressed as a percentage of the areas at risk of ... Myocardial Infarction / blood, pathology*, physiopathology. Myocardium / pathology*. Potassium / blood. Sodium / blood. Grant ... Next Document: Management of patients with prolonged ischemic chest pain without acute myocardial infarction.. ...
http://www.biomedsearch.com/nih/Increase-in-experimental-infarct-size/3376834.html
*  Sulfonylurea receptor 1 subunits of ATP-sensitive potassium channels and myocardial ischemia/reperfusion injury. - PubMed -...
Sulfonylurea receptor 1 subunits of ATP-sensitive potassium channels and myocardial ischemia/reperfusion injury.. Lefer DJ1, ... Myocardial Reperfusion Injury/etiology. *Myocardial Reperfusion Injury/metabolism*. *Myocardial Reperfusion Injury/prevention ... Sulfonylurea Receptor 1 Subunits of ATP-Sensitive Potassium Channels and Myocardial Ischemia/Reperfusion Injury ... and a surprising protection from myocardial ischemia/reperfusion in SUR1-null mice. Here, we review some of the extra- ...
https://www.ncbi.nlm.nih.gov/pubmed/19577714
*  Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion - pdf descargar
Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion. . Biblioteca virtual para leer ... Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion - Descarga este documento en ... Since myocardial ischemia-reperfusion injury is strongly associated with endothelial dysfunction and reactive oxygen species ... Infusion of L-NAME nonspecific blocker of endothelial nitric oxide synthase eNOS along with sivelestat during reperfusion ...
http://libros.duhnnae.com/2017/jul7/150100082667-Sivelestat-Attenuates-Myocardial-Reperfusion-Injury-during-Brief-Low-Flow-Postischemic-Infusion.php
*  British Library EThOS: The role of T lymphocytes in myocardial ischaemia/reperfusion injury
Evidence from animal studies points to a role for lymphocytes, and in particular T cells, in myocardial I/R injury, but this ... but ischaemia/reperfusion (I/R) injury remains an important complication. ... Myocardial infarction is the greatest cause of mortality worldwide, and a source of considerable morbidity. Treatment of ... These findings identify a possible therapeutic target in I/R injury postCPPCI, opening up a new avenue for further research and ...
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697919
*  Investigating the protective role of nitrite against myocardial ischaemia reperfusion injury at University of Birmingham on...
Investigating the protective role of nitrite against myocardial ischaemia reperfusion injury at University of Birmingham, ... paradoxically the process of reperfusion itself causes myocardial injury - a phenomenon called ischaemia-reperfusion injury ( ... Investigating the protective role of nitrite against myocardial ischaemia reperfusion injury University of Birmingham. , ... In experimental studies, it has been shown that nitrite protects against myocardial ischaemia reperfusion injury. In man, we ...
https://www.findaphd.com/phds/project/investigating-the-protective-role-of-nitrite-against-myocardial-ischaemia-reperfusion-injury/?p85053
*  Quercetin postconditioning attenuates myocardial ischemia/reperfusion injury in rats through the PI3K/Akt pathway
Although early reperfusion is essential for myocardial salvage, it induces reperfusion injury, which reduces the benefits of ... Activating PI3K/Akt at the time of reperfusion has been demonstrated to provide protection against myocardial I/R injury (4,18, ... Myocardial ischemia-reperfusion injury: a neglected therapeutic target. J Clin Invest 2013; 123: 92-100, doi: 10.1172/JCI62874 ... Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000861&lng=en&tlng=en