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Application of 8-Br at the end of ischaemia protected the heart during reperfusion. 8-Br promoted binding of HKII to the ... Thus, 8-Br protects the heart when administered before regional ischaemia or at the beginning of reperfusion. This effect is ... Infarct size was evaluated at the end of reperfusion. 8-Br administered before ischaemia attenuated ventricular arrhythmias, ... Haemodynamic function and ventricular arrhythmias were monitored during ischaemia and 2 h reperfusion. ...
Intraoperative tissue hypoperfusion and re-reperfusion injury, which generate reactive oxygen species (ROS), are suggested to ... Imaging Predictors of Left Ventricular Functional Recovery after Reperfusion Therapy of ST-Elevation Myocardial Infarction ... Henry, P.T.; Chandy, M.J. Effect of Ascorbic Acid on Infarct Size in Experimental Focal Cerebral Ischaemia and Reperfusion in a ... The lower postoperative ascorbic acid plasma levels might be the result of severe ischemia/reperfusion injury and might be the ...
Joint Cardioprotective Effect of Vitamin C and Other Antioxidants against Reperfusion Injury in Patients with Acute Myocardial ... An ideal radiotracer for myocardial perfusion imaging should have a high myocardial uptake; a high and stable target-to- ... Despite its peculiar properties, the clinical use of [99mTc]Tc-Teboroxime was quickly abandoned due to its rapid myocardial ... In the last decade, the contribution of DJ-1 to the protection from ischemia-reperfusion injury has been recognized and its ...
Although coronary reperfusion is the most straightforward treatment for limiting the MI size, it has nevertheless been shown to ... Ischemic heart disease (IHD), especially myocardial infarction (MI), is a leading cause of death worldwide. Although coronary ... Nevertheless, the cardiovascular-specific context involving DCs in negotiating the biological response to myocardial injury is ... Ischemic heart disease (IHD), especially myocardial infarction (MI), is a leading cause of death worldwide. ...
... myocardial fibrosis, and heart failure. This review presents recent research advances in SIRT3-mediated metabolic adaptation in ... Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 2011, 123, ... myocardial hypertrophy, myocardial fibrosis, and heart failure. This review presents recent research advances in SIRT3-mediated ... Stanley, W.C.; Recchia, F.A.; Lopaschuk, G.D. Myocardial substrate metabolism in the normal and failing heart. Physiol. Rev. ...
... attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. J. Pharmacol. Exp. Ther 2005, ... Cardioprotection and myocardial salvage by a disodium disuccinate astaxanthin derivative (Cardax). Life Sci 2004, 5, 215-224. [ ... poor aqueous solubility and enabled investigation of this agent in the animal models of myocardial ischaemia and reperfusion ... Thrombosis is a major complication of coronary atherosclerosis that can lead to myocardial infarction. Docosahexaenoic acid ( ...
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A Study on the Protective Effect of sRAGE-MSCs in a Rodent Reperfusion Model of Myocardial Infarction by Delger Bayarsaikhan ... Acute myocardial infarction (AMI) is one of the major leading causes of death in humans globally. Recently, increased levels of ... Acute myocardial infarction (AMI) is one of the major leading causes of death in humans globally. Recently, increased levels of ... Cardiac aging is characterized by increased cardiomyocyte hypertrophy, myocardial stiffness, and fibrosis, which enhance ...
El Morsy, E.M.; Ahmed, M.A.E.; Ahmed, A.A.E. Attenuation of renal ischemia/reperfusion injury by açaí extract preconditioning ... Decrease in myocardial lipid hydroperoxide and MMP-1 activities occurring in doxorubicin cardiotoxicity.. [34]. ... On the other hand, the concentration of myocardial lipid hydroperoxide and the activity of the matrix metalloproteinase MMP-2 ... Treatment performed with EO seed extract improved cardiac dysfunction and exercise intolerance in rats with induced myocardial ...
The results showed that endothelial-derived recombinant human SLPI (rhSLPI) reduced simulated ischemia/reperfusion (I/R)-(81.75 ... Turer, A.T.; Hill, J.A. Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy. Am. J. Cardiol. 2010 ... Singhal, A.K.; Symons, J.D.; Boudina, S.; Jaishy, B.; Shiu, Y.-T. Role of Endothelial Cells in Myocardial Ischemia-Reperfusion ... Myocardial ischemia/reperfusion (I/R) is a pathological process of cardiomyocytes involving inflammatory responses [1]. ...
In our diabetic mouse model, apocynin improved myocardial mitochondrial function and ROS overproduction through the recovery of ... Apocynin can improve myocardial reactive oxygen species overproduction and mitochondrial function through the recovery of the ... Porter, G.A.; Urciuoli, W.R.; Brookes, P.S.; Nadtochiy, S.M. SIRT3 deficiency exacerbates ischemia-reperfusion injury: ... Cardiomyocyte hypertrophy and myocardial fibrosis improved after apocynin treatment (Figure 2E). Meanwhile, apocynin attenuated ...
Holland, N.A. Intratracheal Instillation of Silver Nanoparticles Exacerbates Cardiac Ischemia/Reperfusion Injury in Male ... The acute toxic effects of silver nanoparticles on myocardial transmembrane potential, I Na and I K1 channels and heart rhythm ... AgNP resulted in exacerbation of cardiac ischemic-reperfusion injury.. N/A. [164]. ... Cardiac ischemia reperfusion injury following instillation of 20 nm citrate-capped nanosilver. J. Nanomed. Nanotechnol. 2015, 6 ...
Experimental models of ischemia followed by reperfusion on brain, heart and lesions of the kidney, lung and intestine and for ... secreted by ischemic myocardial cells significantly decreased by 50% in comparison to control animals. Based on these results, ...
Endothelial cells are exposed to hypoxic environments in several physiopathological conditions, such as myocardial infarction, ... Salidroside and Tyrosol from Rhodiola protect H9c2 cell from ischemia/reperfusion-induced apoptosis. Life Sci. 2012, 91, 151- ...
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