Loading...
*  British Library EThOS: Signalling pathways regulating Schwann cell survival and differentiation
I also discovered that STAT3 promotes the expression of myelin proteins in vitro and that it is involved in the timing of ... cell type by promoting its differentiation from the Schwann cell precursor and inhibiting the upregulation of myelin proteins. ... in immature Schwann cells and found that this occurs mainly at the protein, rather than the transcriptional level. ...
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505543
*  Charcot-Marie-Tooth Disease Fact Sheet | National Institute of Neurological Disorders and Stroke
The PMP-22 protein is a critical component of the myelin sheath. Overexpression of this gene causes the structure and function ... making up a single segment of the myelin sheath. This protein may be involved in Schwann cell communication with the axon. ... Myelin twists around the axon like a jelly-roll cake and prevents the loss of electrical signals. Without an intact axon and ... Kinesins are proteins that act as motors to help power the transport of materials along the cell. Other less common forms of ...
https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Charcot-Marie-Tooth-Disease-Fact-Sheet
*  Characterization of a chromosomal duplication in the Plp1 locus: a new mouse model of Pelizaeus-merzbacher disease
Mice with the genomic duplication also display altered expression in other important myelin proteins leading to a disruption in ... which is located on the X chromosome and encodes the most abundant protein of myelin. About 50-75% of PMD cases are due to ... The disease is one of the leukodystrophies, a group of disorders that affect growth of the myelin sheath. It is caused by ... normal myelin formation. Our initial Plp1dup mice characterization studies have only begun to reveal how a duplication of the ...
http://udspace.udel.edu/handle/19716/13069
*  What is Pelizaeus-Merzbacher Disease?
The disease is caused by a mutation in the gene that controls the production of a myelin protein called proteolipid protein-1 ( ... Myelin Project. P.O. Box 39. Pacific Palisades, CA 90272. margaret.weis@myelin.org. http://www.myelin.org. Tel: 800-869-3546 ... The disease is one of a group of gene-linked disorders known as the leukodystrophies, which affect growth of the myelin sheath ...
http://todays-health.blogspot.com/2011/09/what-is-pelizaeus-merzbacher-disease.html
*  "Connexin32 and X-linked Charcot-Marie-Tooth Disease" by Linda Jo Bone, Suzanne M. Deschênes et al.
In peripheral nerve, Cx32 is localized to incisures and paranodes, regions of noncompact myelin within the myelin sheath. This ... In transfected cells, the mutant Cx32 proteins encoded by someCx32mutations fail to reach the cell surface; other mutant ... proteins reach the cell surface, but only one of these forms functional gap junctions. ... More than 130 different mutations have been described, affecting all portions of the Cx32 protein. ...
http://digitalcommons.sacredheart.edu/bio_fac/50/
*  Proposed nomenclature for PNS myelin proteins | SpringerLink
The PO protein. The major glycoprotein of peripheral nerve myelin. Biochim. Biophys. Acta 536:112-121.PubMedGoogle Scholar ... Protein composition of myelin of the PNS. J. Neurochem. 20:1207-1216.PubMedGoogle Scholar ... Comparative studies on the myelin proteins of peripheral nerve and spinal cord. J. Neurochem. 19:2607-2614.PubMedGoogle Scholar ... The proposed amino acid sequence of the P1 protein of rabbit sciatic nerve myelin. Arch. Biochem. Biophys. 153:590-598.PubMed ...
https://link.springer.com/article/10.1007/BF00964152
*  Literature: Myelin protein P0 (IPR029869) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... Literature: Myelin protein P0 (IPR029869). References used in this entry. The following publications were referred to in the ... Myelin P0: new knowledge and new roles.. Eichberg J.. Neurochem. Res. 27 1331-40 2002 PMID: 12512938 Related citations ...
http://www.ebi.ac.uk/interpro/entry/IPR029869/literature
*  Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination | Journal of Neuroscience
The ACPD effect on expression of myelin proteins is dependent on BDNF signaling. The ACPD-mediated increase in myelin protein ... Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination. Clifton G. Fulmer, Melissa W. ... Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination. Clifton G. Fulmer, Melissa W. ... We note an increase in BDNF, as well as myelin proteins 6 h following the ACPD injection. This effect of ACPD is consistent ...
http://www.jneurosci.org/content/34/24/8186
*  Myelin protein zero - Wikipedia
Myelin protein zero has been shown to interact with peripheral myelin protein 22. myelin GRCh38: Ensembl release 89: ... "Peripheral myelin protein 22 and protein zero: a novel association in peripheral nervous system myelin" (PDF). J. Neurosci. ... Myelin protein zero (P0, MPZ) is a glycoprotein which in humans is encoded by the MPZ gene. P0 is a major structural component ... 1993). "Myelin protein zero gene mutated in Charcot-Marie-tooth type 1B patients". Proc. Natl. Acad. Sci. U.S.A. 90 (22): 10856 ...
https://en.wikipedia.org/wiki/Myelin_protein_zero
*  MPZL1 - Myelin protein zero-like protein 1 precursor - Homo sapiens (Human) - MPZL1 gene & protein
... which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks ... Myelin protein zero-like protein 1Add BLAST. 234. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... sp,O95297,MPZL1_HUMAN Myelin protein zero-like protein 1 OS=Homo sapiens OX=9606 GN=MPZL1 PE=1 SV=1 ... "Cloning of human myelin protein zero-like genes by bioinformatics strategy.". Tang D.S., Yu K.P., Tang X.X., Zhang H.L., Pan Q. ...
https://www.uniprot.org/uniprot/O95297
*  Peripheral myelin protein 22 - Wikipedia
Growth arrest-specific protein 3 (GAS-3), also called peripheral myelin protein 22 (PMP22), is a protein which in humans is ... Peripheral myelin protein 22 has been shown to interact with myelin protein zero. GRCh38: Ensembl release 89: ENSG00000109099 ... "Peripheral myelin protein 22 and protein zero: a novel association in peripheral nervous system myelin" (PDF). The Journal of ... of total protein content in compact myelin. Compact myelin is the bulk of the peripheral neuron's myelin sheath, a protective ...
https://en.wikipedia.org/wiki/Peripheral_myelin_protein_22
*  Reevaluation of the growth-permissive substrate properties of goldfish optic nerve myelin and myelin proteins | Journal of...
Reevaluation of the growth-permissive substrate properties of goldfish optic nerve myelin and myelin proteins. M Wanner, DM ... Reevaluation of the growth-permissive substrate properties of goldfish optic nerve myelin and myelin proteins ... Reevaluation of the growth-permissive substrate properties of goldfish optic nerve myelin and myelin proteins ... Reevaluation of the growth-permissive substrate properties of goldfish optic nerve myelin and myelin proteins ...
http://www.jneurosci.org/content/15/11/7500
*  Dejerine-Sottas syndrome associated with point mutation in the peripheral myelin protein 22 (PMP22) gene.
0/Myelin Proteins; 0/PMP22 protein, human; 9007-49-2/DNA From MEDLINE®/PubMed®, a database of the U.S. National Library of ... results either from duplication of a 1.5-megabase DNA region in chromosome 17p11.2-p12 containing the myelin gene PMP22, or ...
http://www.biomedsearch.com/nih/Dejerine-Sottas-syndrome-associated-with/8275092.html
*  Distinct endocytic recycling of myelin proteins promotes oligodendroglial membrane remodeling | Journal of Cell Science
Endocytosis is common to myelin proteins. In light of the fact that the main myelin protein PLP is enriched in LE/Lys ... Endocytic uptake of myelin proteins in oligodendrocytes. (A) Oli-neu cells transiently expressing the myelin proteins PLP, MAG ... Myelin proteins are sorted to distinct endocytic trafficking pathways. The selective endocytosis of myelin proteins from the ... Myelin protein endocytosis was prominent over that of other oligodendroglial plasma membrane proteins not located in myelin, ...
http://jcs.biologists.org/content/121/6/834
*  Structure and expression of a novel compact myelin protein - Small VCP-interacting protein (SVIP) (Journal Article) | SciTech...
Highlights: •SVIP (small p97/VCP-interacting protein) co-localizes with myelin basic protein (MBP) in compact myelin. •We ... Interestingly, we also observed that SVIP co-localizes with myelin basic protein (MBP) in compact myelin, where VCP was absent ... Journal Article: Structure and expression of a novel compact myelin protein - Small VCP-interacting protein (SVIP) ... Title: Structure and expression of a novel compact myelin protein - Small VCP-interacting protein (SVIP) ...
https://www.osti.gov/scitech/biblio/22242137-structure-expression-novel-compact-myelin-protein-small-vcp-interacting-protein-svip
*  Myelin basic protein - Wikipedia
1987). "Myelin deficient mice: expression of myelin basic protein and generation of mice with varying levels of myelin". Cell. ... 2004). "Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin ... "Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3':5'-monophosphate-dependent protein ... Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system ...
https://en.wikipedia.org/wiki/Myelin_basic_protein
*  Myelin Basic Protein | Sigma-Aldrich
... of the myelin sheath in neuronal axons. MBP is commonly used to induce autoimmune encephalomyelitis in animal models. ... Life Science > Metabolomics > Enzymes & Proteins > Learning Center > Structural Proteins > Myelin Basic Protein ... Myelin basic protein (MBP) comprises about 20% of the myelin sheath in neuronal axons. MBP is commonly used to induce ...
https://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/learning-center/structural-proteins/myelin-basic-protein.html
*  Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2. | Physician's Weekly for...
... were discovered in the abundant peripheral myelin protein P2. These mutations trigger abnormal myelin structure, leading to ... P2 is a myelin-specific protein expressed by Schwann cells that binds to fatty acids and membranes, contributing to peripheral ... Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2. by Physicians Weekly , ... In addition, P2 disease mutations affect protein dynamics. Both fatty acid binding by P2 and the kinetics of its membrane ...
https://www.physiciansweekly.com/molecular-mechanisms-of-charcot-marie-tooth-neuropathy-linked-to-mutations-in-human-myelin-protein-p2-2/
*  Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point...
Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point ... Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point ...
https://www.zora.uzh.ch/id/eprint/116005/
*  Myelin proteins synonyms, Myelin proteins antonyms - FreeThesaurus.com
Antonyms for Myelin proteins. 2 synonyms for myelin: medulla, myeline. What are synonyms for Myelin proteins? ... Myelin proteins synonyms, Myelin proteins antonyms - FreeThesaurus.com https://www.freethesaurus.com/Myelin+proteins ... Many different brain proteins, including myelin proteins as well as astrocytic or neuronal proteins, can induce a T-cell ... myelin. (redirected from Myelin proteins). Also found in: Dictionary, Medical, Encyclopedia. #vtZoom,.vt-link{cursor:pointer} . ...
https://www.freethesaurus.com/Myelin+proteins
*  Autoantibodies to Myelin Basic Protein In Multiple Sclerosis | SpringerLink
Warren KG, Catz I: A correlation between CSF myelin basic protein and anti-myelin basic protein in multiple sclerosis patients ... Braun PE, Brostoff SW: Proteins of myelin. In Morell P (ed): Myelin, Plenum Press, New York, 1977, pp 201-230Google Scholar ... Wajgt A, Gorny M: CSF antibodies to myelin basic protein and to myelin-associated glycoprotein in multiple sclerosis - evidence ... Whitaker JN: The antigenicity of myelin basic protein: Production of antibodies to encephalitogenic protein with DNA- ...
https://link.springer.com/chapter/10.1007/978-1-4613-0777-8_17
*  'myelin basic proteins' Protocols and Video...
... myelin basic proteins' include 'Monitoring Cleaved Caspase-3 Activity and Apoptosis of Immortalized Oligodendroglial Cells ... Myelin Basic Proteins: A group of 7 proteins produced from a single gene by alternate splicing found in central and peripheral ... myelin basic protein 18.5-kDa is often referred to as the P1 protein. (From Siegel et al., Basic Neurochemistry, 5th ed, p130, ... nervous system myelin. The major basic protein (Mbp) has long been of interest because it is the antigen, that, when injected ...
https://www.jove.com/keyword/myelin+basic+proteins
*  Domain architectures: Myelin proteolipid protein PLP (IPR001614) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... Domain architectures: Myelin proteolipid protein PLP (IPR001614). Showing 1 to 9 of 9 results ...
http://www.ebi.ac.uk/interpro/entry/IPR001614/domain-organisations
*  Anti-Myelin Basic Protein antibody (ab123499) | Abcam
Chicken polyclonal Myelin Basic Protein antibody validated for WB, ICC/IF and tested in Human, Mouse, Rat and Cow. Immunogen ... Anti-Myelin Basic Protein antibody. See all Myelin Basic Protein primary antibodies. ... Mixture of 3 Human Myelin Basic Protein synthetic peptides, representing the different forms of the protein (alternate ... Anti-Myelin Basic Protein antibody (ab123499) at 1/10000 dilution + whole tissue homogenate of Rat spinal cord. Predicted band ...
http://www.abcam.com/myelin-basic-protein-antibody-ab123499.html
*  Anti-Myelin Basic Protein antibody (ab28541) Protocols
Abcam provides specific protocols for Anti-Myelin Basic Protein antibody (ab28541) : Western blot protocols, ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ...
http://www.abcam.com/myelin-basic-protein-antibody-ab28541-protocols.html