Keywords : micronucleus test; mutagenicity; electromagnetic fields. · text in English · English ( pdf epdf ) ...
... indicates the levels of mutagenicity as the number of revertant colonies obtained increases 10 times. ... Compound was tested for the mutagenicity activity in the Salmonella Typhimurium reverse mutation assay; +++- ...
"Efficiency of Batteries of Tests for Estimating Potential Mutagenicity of Chemicals, Russian Journal of Genetics" on DeepDyve, ... Amess test, the test for chromosome aberrations in vitro, the test for cytogenetic defects in vivo, and the test for dominant ... The results of tests in each test system has been presented as the probability to obtain a positive result in the given test ... Efficiency of Batteries of Tests for Estimating Potential Mutagenicity of Chemicals. Efficiency of Batteries of Tests for ...
... although the Ames test may not be a good indicator for nano-object mutagenicity. Clift, Martin J. D.; Raemy, David O.; Endes, ... were the only particle stimulus to induce any significant mutagenicity through the Ames test. Comparison with a sophisticated ... and how such an interaction may relate to the potential mutagenicity of nano-objects. Transmission electron microscopy showed ... nano-object(s) ; nano-bacterial interactions ; mutagenicity ; Ames test ; mammalian cells. OAI-PMH Identifier. *oai:doc.rero.ch ...
... for mutagenicity, in Salmonella typhimurium; 35 of the chemicals were tested more than once in the same or different ... The tests were conducted using a preincubation protocol in the absence of exogenous metabolic activation, and in the presence ... Some of the volatile chemicals were also tested in desiccators. A total of 120 chemicals were mutagenic or weakly mutagenic, 3 ... The remaining 16 chemicals produced different responses in the two or three laboratories in which they were tested. The results ...
A significant decrease in mutagenicity in Salmonella assay and both CA and SCE were observed in all the different ... pyrene induced mutagenicity and genotoxicity by black tea polyphenols theaflavins and thearubigins in multiple test systems.. * ... Genotoxicity, Mutagenicity and Carcinogenicity and REACH. Kristine B. Gutzkow + 1 • Oct 17, 2017 ...
Mutagenicity Testing. The mutagenicity of 2ME was tested in Salmonella typhimurium strains TA 1535, TA 1537, TA 98, and TA 100 ... Mutagenicity Testing. The mutagenicity of 2EE was tested in Salmonella typhimurium strains TA 1535, TA 1537, TA 98, and TA 100 ... Ong, T.: Mutagenicity testing of 2-ethoxy/methoxy ethanol (September 29, 1980). ... Carcinogenicity Testing. The Department of Health and Human Services National Toxicology Program is currently testing 2EE for ...
Ames testing laboratory, fluctuation assay, Ames Express strains, S9 liver fractions, Biotoxicology, mutagenicity, revertants ... Mutagenicity Testing. EBPI offers a full line of mutagenicity (Ames) tests to detect direct DNA damage in both 96 well or 384 ... Test Method Options. EBPI Analytics also offers three testing methods for our mutagenicity assays that can be chosen depending ... Ames Test Information Bacterial mutagenicity testing was pioneered in the late 1960s and early 1970s by Bruce Ames and Phil ...
Mutagenicity testing. In 1996, IPCS produced harmonized methods for the prediction and quantification of human/mutagenic hazard ... The Scheme is published in the article Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized ... Selection of appropriate in vitro and in vivo tests as well as a strategy for germ cell testing are described. ... Otherwise known as the IPCS Qualitative Scheme for Mutagenicity, and published in the journal Mutation Research, this guidance ...
Ames Mutagenicity Test. The Ames Mutagenicity test is used to determine the potential mutagenic activity of an extract from a ... A spot test is also performed in which the extracts of the test article are spotted on a plate containing the test organism ... The tests are performed by mixing an extract of the test article with the test organism in a soft agar solution, which contains ... The Ames Mutagenicity test employs several strains of Salmonella typhimurium which have been selected based on their ...
Evaluation and testing of drugs for mutagenicity : principles and problems, report of a WHO scientific group [meeting held in ... by WHO Scientific Group on the Evaluation and Testing of Drugs for Mutagenicity: Principles and Problems , World Health ... by WHO Scientific Group on the Evaluation and Testing of Drugs for Mutagenicity : Principles and Problems , World Health ... by WHO Scientific Group on the Evaluation and Testing of Drugs for Mutagenicity: Principles and Problems , World Health ...
Testing the mutagenicity of malondialdehyde and formaldehyde by the Drosophila mosaic and the sex-linked recessive lethal tests ... Haworth S, Lawlor T, Mortelmans K, Speck W, Zeiger E [1983]. Salmonella mutagenicity test results for 250 chemicals. Environ ... 1984]. Valeraldehyde tested negative in the S. typhimurium assay, and no other testing is scheduled [NTP 1990]. ... mammalian-microsome mutagenicity test. Mutat Res 31:347-363.. ANSI [1988]. American national standard fundamental governing the ...
Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays. In: Mutation ... Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays Primary tabs. *Détail ... Home» Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays ... For example, Liver S9 preparations may be used with some indicator systems (e.g., bacterial mutagenicity), and metabolically ...
The qualitative relationship between carcinogenicity and mutagenicity (DNA-damaging activity), based on chemicals which are ... Confidence in positive tests results is increased when they are confirmed in multiple short-term tests using nonrepetitive end ... 18727827 - Testing for allergic disease: parameters considered and test value.. 25096827 - North-american survey on hpv-dna and ... In the absence of studies in man, long-term animal tests are still today the only ones capable of providing evidence of the ...
11]If no preliminary cytotoxicity test was performed, enter "not performed." [12]If more than one mutagenicity test was ... B. Test Title/Report Number: C. Name of Author or Director of Test: D. Name and Address of Testing Laboratory:. E. Date of Test ... This template is for the S. typhimurium Test (Ames Test), the most commonly used reverse mutation test. In addition to the S. ... 23]Briefly summarize the second test as you did the first test. Do the results of the second test agree or disagree with those ...
The Ames test for mutagenicity. The test uses a strain of Salmonella bacteria that require histidine in the medium because of a ... In one popular test for mutagenicity, the carcinogen is mixed with an activating extract prepared from rat liver cells (to ... When mutagenicity data from various sources are analyzed, one finds that the majority of identified carcinogens are mutagens. ... Even when evidence is obtained that a substance may be carcinogenic, either from epidemiology or from laboratory tests, it may ...
MUTAGENICITY AND ANTIMUTAGENICITY OF MEDICINAL PLANTS, NOM NANG, SUN SOKE AND STEVIA, EXTRACTS IN AMES TEST. ... But co-mutagenicity to Trp-P-1 was observed in 80% alcoholic extract of Nom Nang and to AFB1 was in aqueous extract of Sun Soke ... Sun Soke and Stevia showed non-genotoxicity in Ames test in the presence or absencc of metabolic enzymes activation. However, ...
Mutagenicity of fractionated test material from the synthetic fuel technology with bacterial systems Description: The ... Description: Sufficient supplies were purchased to test ten explosives using the NOL Card Gap Test as described in Department ... Tests were performed while firing coal as the primary fuel, and natural gas and coal as reburn fuels. The results for the ... The filter and line were cleaned periodically throughout testing to avoid ash build-up; ash has also been shown to convert NO[ ...
We examined the mutagenicity of cigarette smokers urine in 32 healthy male cigarette smoker and 37 healthy male non-smoker. ... The mutagens were measured by using an S9-mediated Salmonella mutagenicity test on strain TA98. Compared with those with non- ... Heavy Cigarette Smokers Show Higher Mutagenicity in Urine Mutat Res. 1997 Jan 3;373(1):107-11. doi: 10.1016/s0027-5107(96)00195 ... We examined the mutagenicity of cigarette smokers urine in 32 healthy male cigarette smoker and 37 healthy male non-smoker. ...
The in vitro PIG-A gene mutation assay: mutagenicity testing via flow cytometry based on the glycosylphosphatidylinositol (GPI ...
However, its mutagenicity in vitro and in vivo has not yet been reported. The Ames test for mutagenicity is used worldwide. The ... need modified Ames tests to assay their in vitro mutagenicity. The mutagenicity of SAA was evaluated by the standard and two ... The standard Ames test showed a positive result for mutagenicity of SAA. In contrast, a negative response was obtained with the ... The standard Ames test was not suitable for evaluating the mutagenicity of SAA, because false-positive result could be resulted ...
The present study investigated the in silico and in vitro mutagenicity of the fruit, leaf, seed and stem extracts of Avicennia ... The mutagenicity of these extracts was also investigated using Ames test. In silico analysis of 15 dominant compounds of the ... Activity of Avicennia marina Methanol Extracts on Proliferation of Lymphocytes and their Mutagenicity Using Ames Test and In ... Activity of Avicennia marina Methanol Extracts on Proliferation of Lymphocytes and their Mutagenicity Using Ames Test and In ...
Mutagenicity Tests. Occupational Exposure*. Phlebotomy Polymerase Chain Reaction. Polymorphism, Single Nucleotide. Pregnancy ...