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*  Gene Discovery by MMTV Mediated Insertional Mutagenesis | SpringerLink
Gene Discovery by MMTV Mediated Insertional Mutagenesis. In: Dupuy A., Largaespada D. (eds) Insertional Mutagenesis Strategies ... Retroviral insertional mutagenesis (IM) screens provide one of the most efficient tools to identify genes involved in ... 2007). MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer. Nature of Genetics ... Lee, F. S., Lane, T. F., Kuo, A., Shackleford, G. M., & Leder, P. (1995). Insertional mutagenesis identifies a member of the ...
https://link.springer.com/chapter/10.1007/978-1-4419-7656-7_3
*  Insertional Mutagenesis - Definitive Vector Study 11042
... Testing Status of Insertional Mutagenesis - Definitive Vector Study ... Insertional mutagenesis studies using various vector exposures (LTR; uORF LTR, SIN, EFS LTR, and P(-) SIN vectors. ...
https://ntp.niehs.nih.gov/testing/status/agents/ts-11042.html
*  Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana | Science
Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana. By José M. Alonso, Anna N. Stepanova, Thomas J. Leisse, ... Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana. By José M. Alonso, Anna N. Stepanova, Thomas J. Leisse, ... Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana Message Subject. (Your Name) has forwarded a page to you from ...
http://science.sciencemag.org/content/301/5633/653?ijkey=7b4bc0f9b25c76f76024e79795b6771e9a08bf11&keytype2=tf_ipsecsha
*  Random insertional mutagenesis in fungal genomes to identify virulence factors
ATMT-based approaches such as random insertional mutagenesis and targeted knockout are widely used for gene functional analysis ... Here, we describe a protocol for the identification of pathogenicity and virulence genes through random insertional mutagenesis ...
http://library.wur.nl/WebQuery/wurpubs/425890
*  European Medicines Agency - Multidisciplinary - Management of clinical risks deriving from insertional mutagenesis
Gene therapy medicinal products, insertional mutagenesis, integration. Description. This document discusses the factors ... the strategies to reduce the risk associated to insertional mutagenesis and the assays to evaluate vector oncogenesis at the ...
http://www.ema.europa.eu/ema/index.jsp?curl=pages/regulation/general/general_content_001370.jsp&mid=WC0b01ac058002958d
*  INSERTIONAL MUTAGENESIS IN THE DIPLOID STRAWBERRY (FRAGARIA VESCA)
Challenges and Opportunities for Horticulture in the World INSERTIONAL MUTAGENESIS IN THE DIPLOID STRAWBERRY (FRAGARIA VESCA) ... INSERTIONAL MUTAGENESIS IN THE DIPLOID STRAWBERRY (FRAGARIA VESCA). Authors: R.E. Veilleux, T. Oosumi, P.A. Wadl, A.J. Baxter, ... Insertional mutant collections are essential tools in plant genomic research and functional genomics. Extensive collections in ... We have therefore undertaken a program to develop an insertional mutant collection of the diploid strawberry, Fragaria vesca, ...
http://www.actahort.org/books/941/941_3.htm
*  Insertional mutagenesis - Wikipedia
Insertional mutagenesis is mutagenesis of DNA by the insertion of one or more bases. Insertional mutations can occur naturally ... Directed mutagenesis Insertion (genetics) PCR mutagenesis Site-directed mutagenesis Transposon mutagenesis Biology-online Biffi ... Recombinant DNA Insertional inactivation Carlson CM, Largaespada DA (July 2005). "Insertional mutagenesis in mice: new ... mutagenesis caused by viral infections is a fairly common occurrence. Not all integrating viruses cause insertional mutagenesis ...
https://en.wikipedia.org/wiki/Insertional_mutagenesis
*  Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB | PNAS
Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB. Tao Lu, Mark W. ... While MLV-based insertional mutagenesis has a long history in gene discovery, we understand HIV-based insertion less well. ... Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB ... Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB ...
https://www.pnas.org/content/106/38/16339
*  Mouse genetic corneal disease resulting from transgenic insertional mutagenesis | British Journal of Ophthalmology
Another possibility is that the transgenic insertional mutagenesis affected a regulatory gene, such as Pax6 or a similar gene. ... Rijkers T, Peetz A, Ruther U. Insertional mutagenesis in transgenic mice. Transgenic Res 1994;3:203-15. ... Conclusion: Eye abnormality in T27aT15 mice results from random insertional mutagenesis of the transgene as it was only ... Insertional mutation of 'classical' and novel genes in transgenic mice. Trends Genet 1992;8:341-4. ...
http://bjo.bmj.com/content/88/3/428
*  Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for...
2011) Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis. Nat Genet 43( ... Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for ... Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for ... Sleeping Beauty (SB) transposon-based insertional mutagenesis screening in mice has emerged as a powerful, functional approach ...
http://www.pnas.org/content/114/11/E2215.full
*  An Insertional Mutagenesis and Immunochemical Analysis of Visual Arrestin Interaction with Rhodopsin | IOVS | ARVO Journals
A Dinculescu, JH McDowell, S Amici, D Dugger, N Richards, PA Hargrave, WC Smith; An Insertional Mutagenesis and Immunochemical ... An Insertional Mutagenesis and Immunochemical Analysis of Visual Arrestin Interaction with Rhodopsin ... An Insertional Mutagenesis and Immunochemical Analysis of Visual Arrestin Interaction with Rhodopsin ... Our goal was to further probe the structural determinants of arrestin function by using a combined insertional mutagenesis and ...
https://iovs.arvojournals.org/article.aspx?articleid=2418664
*  Winning Abstracts from the 2010 Medical Student Abstract Competition: Assessing Potential Toxicities Of Gene Therapy:...
Insertional Mutagenesis Risk Following Aav Vector-mediated Gene Transfer Author: Hojun Li, University of Pennsylvania School of ... Insertional Mutagenesis Risk Following Aav Vector-mediated Gene Transfer. Winning Abstracts from the 2010 Medical Student ... Insertional Mutagenesis Risk Following Aav Vector-mediated Gene Transfer. Author: Hojun Li, University of Pennsylvania School ... Insertional Mutagenesis Risk Following Aav Vector-mediated Gene Transfer. Winning Abstracts from the 2010 Medical Student ...
https://www.acponline.org/membership/medical-students/acp-impact/archive/september-2010/winning-abstracts-from-the-2010-medical-student-abstract-competition-assessing-potential-toxicities
*  Molecular mechanisms of insertional mutagenesis in yeasts and mycelium fungi, Russian Journal of Genetics | 10.1134...
"Molecular mechanisms of insertional mutagenesis in yeasts and mycelium fungi, Russian Journal of Genetics" on DeepDyve, the ... Molecular mechanisms of insertional mutagenesis in yeasts and mycelium fungi. Molecular mechanisms of insertional mutagenesis ... Molecular mechanisms of insertional mutagenesis in yeasts and mycelium fungi. Dmytruk, K.; Sibirny, A. ... "Molecular mechanisms of insertional mutagenesis in yeasts and mycelium fungi." Russian Journal of Genetics 43.8 (2007): 835-845 ...
https://www.deepdyve.com/lp/springer-journals/molecular-mechanisms-of-insertional-mutagenesis-in-yeasts-and-mycelium-9dOox8gEGT
*  "Analysis of HIV-2 Vpx by Modeling and Insertional Mutagenesis" by Lisa A. Mahnke, Michael Belshan et al.
1 Vpr in a central helical domain and probed regions of Vpx by insertional mutagenesis. A predicted loop between helices two ... Other insertional mutants in the predicted loop and in a linker region between the central domain and the C-terminus may be ... 1 Vpr in a central helical domain and probed regions of Vpx by insertional mutagenesis. A predicted loop between helices two ... Other insertional mutants in the predicted loop and in a linker region between the central domain and the C-terminus may be ...
http://digitalcommons.unl.edu/virologypub/83/
*  Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice - Universiteit Leiden
Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice. In this thesis, we used ... Using insertional mutagenesis to identify breast cancer drivers and therapy resistance genes in mice ... Secondly, we employed a Sleeping Beauty (SB)-based insertional mutagenesis screen in conditional Cdh1 knockout mice to identify ... We show that active transposon mutagenesis drives ILC formation and analysis of common insertion sites in SB-induced tumors ...
https://www.universiteitleiden.nl/onderzoek/onderzoeksoutput/wiskunde-en-natuurwetenschappen/using-insertional-mutagenesis-to-identify-breast-cancer-drivers-and-therapy-resistance-genes-in-mice
*  Inducible-targeted tagging system for localized insertional mutagenesis in arabidopsis thaliana | ScholarBank@NUS
Inducible Insertional mutagenesis, Ac/Ds Transposons, Arabidopsis thaliana, Gene trap, Genome Analysis, Saturation mutagenesis ... The present study describes a system of inducible insertional mutagenesis based on the Ac-Ds family of transposons for targeted ... BINDU NISHAL (2005-09-02). Inducible-targeted tagging system for localized insertional mutagenesis in arabidopsis thaliana. ... I mapped 40 single copy lines by TAIL-PCR, which could be used as potential launch pads for heat shock mutagenesis. Using a ...
http://scholarbank.nus.edu.sg/handle/10635/14973
*  "Insertional mutagenesis of the signal transduction pathway for low CO2" by Kyujung Van
... phenotype was used to generate insertional mutants, and Cah1 expression and having high CO2-requiring (HCR) phenotype were used ... Van, Kyujung, "Insertional mutagenesis of the signal transduction pathway for low CO2 acclimation in Chlamydomonas reinhardtii ... Insertional mutagenesis of the signal transduction pathway for low CO2 acclimation in Chlamydomonas reinhardtii ... phenotype was used to generate insertional mutants, and Cah1 expression and having high CO2-requiring (HCR) phenotype were used ...
https://lib.dr.iastate.edu/rtd/458/
*  iMapper: a web application for the automated analysis and mapping of insertional mutagenesis sequence data against Ensembl...
We have developed a web application called iMapper (Insertional Mutagenesis Mapping and Analysis Tool) for the efficient ... iMapper scans and trims the sequence to remove the linker and sequences derived from the insertional mutagen. The software then ... SUMMARY Insertional mutagenesis is a powerful method for gene discovery. To identify the location of insertion sites in the ... Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells.. *Yang Du, ...
https://www.semanticscholar.org/paper/iMapper%3A-a-web-application-for-the-automated-and-of-Kong-Zhu/08aa55ce8c43d8dbe31a5f0997e72109e1fc9b3b
*  Download Insertional Mutagenesis Strategies In Cancer Genetics
metals of asocial systems and of others from download insertional animals are viewing disappointed for moment summer. ... The download insertional mutagenesis strategies in cancer genetics networks deal layered in the Intellectuals of Adhirons, and ... Download Insertional Mutagenesis Strategies In Cancer Genetics. Yarn of the Month. contaminants on download insertional ... This download insertional mutagenesis strategies multi-organisation will share to walk sectors. In download insertional to help ...
http://patriciasyarns.com/ebook/download-insertional-mutagenesis-strategies-in-cancer-genetics
*  A Novel Lentiviral Vector Model to Investigate the Mechanism of Insertional Mutagenesis by Aberrant Splicing - UCL Discovery
Retrovirus vector-mediated insertional mutagenesis (IM) can lead to serious cancerous risks in gene therapy. Although multiple ... A Novel Lentiviral Vector Model to Investigate the Mechanism of Insertional Mutagenesis by Aberrant Splicing. Doctoral thesis ... A Novel Lentiviral Vector Model to Investigate the Mechanism of Insertional Mutagenesis by Aberrant Splicing ... A Novel Lentiviral Vector Model to Investigate the Mechanism of Insertional Mutagenesis by Aberrant Splicing. ...
http://discovery.ucl.ac.uk/1542407/
*  "Insertional Mutagenesis Screen Identifies HACE1 as a HER2 Cooperating " by Erik T. Goka
... we used an insertional mutagenesis screen on cells isolated from wild-type neu expressing mice and identified the E3 ligase ... Goka, Erik T., "Insertional Mutagenesis Screen Identifies HACE1 as a HER2 Cooperating Tumor Suppressor Whose Loss Results In ... Insertional Mutagenesis Screen Identifies HACE1 as a HER2 Cooperating Tumor Suppressor Whose Loss Results In Hyperactive Rac ... we used an insertional mutagenesis screen on cells isolated from wild-type neu expressing mice and identified the E3 ligase ...
https://scholarlyrepository.miami.edu/oa_dissertations/1411/
*  Germline Transgenesis and Insertional Mutagenesis in Schistosoma mansoni Mediated by Murine Leukemia Virus (pdf) | Paperity
Germline Transgenesis and Insertional Mutagenesis in Schistosoma mansoni Mediated by Murine Leukemia Virus, PLOS Pathogens, ... Germline Transgenesis and Insertional Mutagenesis in Schistosoma mansoni Mediated by Murine Leukemia Virus. PLOS Pathogens, Jul ... Germline Transgenesis and Insertional Mutagenesis in Schistosoma mansoni Mediated by Murine Leukemia Virus. et al. (2012) ... These findings represent the first report of wide-scale insertional mutagenesis of schistosome chromosomes and the first report ...
http://paperity.org/p/60879085/germline-transgenesis-and-insertional-mutagenesis-in-schistosoma-mansoni-mediated-by
*  Retroviruses and insertional mutagenesis in mice: proviral integratio" by P Soriano, T Gridley et al.
Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death. ... Soriano, P; Gridley, T; and Jaenisch, R, " Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 ...
https://mouseion.jax.org/stfb1980_1989/955/
*  Insertional mutagenesis of the maize P gene by intragenic transposition of Ac - CSHL Scientific Digital Repository
Athma, P., Grotewold, E., Peterson, T. (1992) Insertional mutagenesis of the maize P gene by intragenic transposition of Ac. ... Insertional mutagenesis of the maize P gene by intragenic transposition of Ac ... Base Sequence Cloning, Molecular *DNA Transposable Elements Gene Expression Molecular Sequence Data *Mutagenesis, Site-Directed ... mutagenesis. bioinformatics , genomics and proteomics , genetics & nucleic acid processing , DNA, RNA structure, function, ...
http://repository.cshl.edu/31798/
*  A resource of mapped dissociation launch pads for targeted insertional mutagenesis in the Arabidopsis genome - CSHL Scientific...
We describe a new resource for targeted insertional mutagenesis in Arabidopsis using a maize (Zea mays) Activator/Dissociation ... A resource of mapped dissociation launch pads for targeted insertional mutagenesis in the Arabidopsis genome ... A resource of mapped dissociation launch pads for targeted insertional mutagenesis in the Arabidopsis genome. Plant physiology ... Because Ds elements preferentially transpose to nearby genomic sites, they can be used in targeted mutagenesis of linked genes ...
http://repository.cshl.edu/27943/