Find a Scientist | Fox Chase Cancer Center - Philadelphia PA
JCI - The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells
Understanding the molecular mechanisms of metastasis is a major step in designing effective cancer therapeutics. Here we show ... on lung tumor tissue cDNA from 80 lung cancer patients of the indicated stages of disease. The stage II, III, and IV cDNA ... The selective expression of Brachyury in tumor cells and its role in EMT and cancer progression suggest that Brachyury may be ... Metastatic disease is responsible for the majority of human cancer deaths. ...
Proteome Profiler Mouse Cytokine Array Kit, Panel A (ARY006): R&D Systems
Molecular Cancer Therapeutics, 2022-11-03;0(0):. 2022-11-03 * Glutamyl-prolyl-tRNA synthetase 1 coordinates early endosomal ... Androgen receptor in cancer-associated fibroblasts influences stemness in cancer cells Authors: CP Liao, LY Chen, A Luethy, Y ... Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid- ... Cancer Res., 2018-09-19;0(0):. 2018-09-19 * CLEC16A regulates splenocyte and NK cell function in part through MEK signaling ...
2005 Publications
Molecular Cancer Therapeutics 2005, 4(6), 1019-1025.. DOI: 10.1158/1535-7163.MCT-04-0342 ... Terphenyl-based Bak-BH3 α-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.. Journal of the American ... Journal of Computer Aided Molecular Design 2005, 19(12), 871-875.. DOI: 10.1007/s10822-005-9030-2 ...
The Conference Forum Announces 4th Annual "Patients as Partners" US Event
Janet Freeman-Daily, Lung Cancer Patient & Activist. * Ken Getz, MBA, Director of Sponsored Research / Founder, Tufts CSDD / ... Gary Ostroff, PhD, Research Professor in Molecular Medicine, UMass Medical School. * Christine Pierre, President, Society for ... Jamie Ring, Head, Patient Advocacy, Spark Therapeutics. * Suzanne Schrandt, JD, Director, Patient Engagement, Arthritis ... Sarah Krüg, CEO / President, Cancer 101 / Society of Participatory Medicine * Deb Maskens, Vice Chair, International Kidney ...
Glycobiology - Research output - Lund University
Mani, K., Sandgren, S., Welch, J., Cheng, F., Svensson, K., Persson, L. & Belting, M., 2007, In: Molecular Cancer Therapeutics. ... Cheng, F., Johnsson, R., Nilsson, J., Fransson, L-Å., Ellervik, U. & Mani, K., 2009, In: Cancer Letters. 273, p. 148-154. ... Aili, U., Johnsson, R., Fransson, L-Å., Ellervik, U. & Mani, K., 2010, In: Cancer Research. 70, 9, p. 3771-3779. Research ... Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior. Cheng, F. ...
New novel non-MHC genes were identified for cervical cancer with an integrative analysis approach of transcriptome-wide...
Eps8 decreases chemosensitivity and affects survival of cervical cancer patients. Molecular cancer therapeutics. 2008;7:1376-85 ... Comprehensive analysis of HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 loci and squamous cell cervical cancer risk. Cancer ... Molecular & cellular proteomics: MCP. 2010;9:1369-82 55. Deliot N, Constantin B. Plasma membrane calcium channels in cancer: ... B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer. International journal of cancer. 2016;139: ...
Philip Dunne - Research output - Queen's University Belfast
Molecular Cancer Therapeutics. 20, 9, p. 1627-1639 13 p.. Research output: Contribution to journal › Article › peer-review ... 1) Molecular subtyping in colorectal cancer. 2) Stromal and immune interactions in colorectal cancer. 3) Tumour invasion and ... MmCMS: mouse models consensus molecular subtypes of colorectal cancer. Amirkhah, R., Gilroy, K., Malla, S. B., Lannagan, T. R ... Distinct molecular profiles of sporadic early onset colorectal cancer: a population-based cohort and systematic review. ...
Fox Chase Cancer Center Archives | Caris Life Sciences
Molecular Cancer Therapeutics. Multidisciplinary Head and Neck Cancer Symposium. Nature Communications. Natures Scientific ... Cancer Biology and Therapy. Cancer Medicine. Cancer Reviews. Cancers. Case Reports in Oncological Medicine. Cells. Clinical ... International Journal of Cancer. International Journal of Gynecological Cancer. International Journal of Molecular Sciences. ... Clinical Genitourinary Cancer. CMS. Cureus. Current Oncology. EACR. ECCO. EClinicalMedicine. ESMO. ESMO GI. ESMO Open. European ...
RCSB PDB - 3KAF: Structure-guided design of alpha-amino acid-derived Pin1 inhibitors
The peptidyl prolyl cis/trans isomerase Pin1 is a promising molecular target for anti-cancer therapeutics. Here we report the ... The peptidyl prolyl cis/trans isomerase Pin1 is a promising molecular target for anti-cancer therapeutics. Here we report the ... and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General ...
Columbia University Archives | Caris Life Sciences
Molecular Cancer Therapeutics. Multidisciplinary Head and Neck Cancer Symposium. Nature Communications. Natures Scientific ... Cancer Biology and Therapy. Cancer Medicine. Cancer Reviews. Cancers. Case Reports in Oncological Medicine. Cells. Clinical ... International Journal of Cancer. International Journal of Gynecological Cancer. International Journal of Molecular Sciences. ... Clinical Genitourinary Cancer. CMS. Cureus. Current Oncology. EACR. ECCO. EClinicalMedicine. ESMO. ESMO GI. ESMO Open. European ...
Asad Ali | IntechOpen
The landscape of cancer therapeutics is rapidly advancing with development of new and sophisticated approaches to diagnostic ... It embraces multiple techniques to arrive at comprehensive diagnosis, molecular images and an individualized treatment regimen ... Theranostic approach to management of cancer offers numerous advantages. They are designed to monitor cancer treatment in real ... Cancer is a leading cause of mortality worldwide, accounting for 8.8 million deaths in 2015. ...
Simon Cook - Publications | Babraham Institute
view abstract Molecular cancer therapeutics, PMID: 31748345 20 Nov 2019 An mTORC1-to-CDK1 Switch Maintains Autophagy ... In this article, we review FGFR signalling and describe recent advances in cancer genomics and cancer cell biology that ... view abstract International journal of cancer. Journal international du cancer, PMID: 19637312 2009 ... Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival. ...
Precision Medicine Market Size 2020, Share, Growth By 2025, Global Industry Research, Report, SWOT Analysis, Development Trends...
Targeted Therapeutics, Pharmacogenomics (PGX), Molecular Diagnostics), Therapeutics (Cancer/Oncology, Cardiovascular Disease ( ... medicine includes the system biology and panomics for determining the reason for the illness of the patient at a molecular ... Molecular Health GmbH, and Precision for Medicine. ... Ultrasound-Equipped Bra Monitors for Breast Cancer. 3D Printed ...
Arcangeli Annarosa | Scheda personale | Università degli Studi di Firenze | UniFI
... an effective strategy against solid cancers. MOLECULAR CANCER THERAPEUTICS, pp. 1-37, ISSN:1535-7163 DOI ... hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer.. CANCER CELL INTERNATIONAL, vol. 18 ... MOLECULAR CANCER THERAPEUTICS, vol. 22, pp. 343-356, ISSN:1535-7163 DOI ... CANCER RESEARCH, vol. 64, pp. 606-611, ISSN:0008-5472, American Association of Cancer Research:150 South Independence Mall West ...
Center for RNA Biology: From Genome to Therapeutics - University of Rochester Medical Center
DBB Seminar: Molecular Tracking of Differentiation Cascades and Mechanisms of Direct Repression by a Transcription Activator. ... DBB Seminar: "Translational Control of Breast Cancer Metastasis". Robert Schneider, PhD - Albert Sabin Professor, Department of ... Eric Wagner (co-sponsored by the NIH NIGMS T32 Training Grant in Cellular, Biochemical and Molecular Sciences, Dr. Lynne Maquat ... Sarah Loerch, PhD - Assistant Professor, Department of Chemistry & Biochemistry and Center for Molecular Biology of RNA, ...
SAA2 Human | Amyloid A2 protein | ProSpec
... non-glycosylated polypeptide chain containing N-terminal Met and having a molecular mass of 11.76kDa. ... Implications in Disease and Therapeutics:. Altered levels of SAA2 are associated with various diseases, including chronic ... inflammatory disorders, cancer, and metabolic syndromes. Understanding the molecular mechanisms underlying SAA2 dysregulation ... non-glycosylated polypeptide chain containing N-terminal Met and having a molecular mass of 11.76kDa. SAA2Human is purified by ...
Timothy D. Johnson - Google Scholar
Molecular cancer therapeutics 2 (6), 581-587, 2003. 316. 2003. Meta-analysis of functional neuroimaging studies of emotion ... Evaluation of cancer therapy using diffusion magnetic resonance imaging. BD Ross, BA Moffat, TS Lawrence, SK Mukherji, SS ... The parametric response map is an imaging biomarker for early cancer treatment outcome. CJ Galb n, TL Chenevert, CR Meyer, C ... The functional diffusion map: an imaging biomarker for the early prediction of cancer treatment outcome. BA Moffat, TL ...
Activation of the Mouse TATA-less and Human TATA-Containing UDP-Glucuronosyltransferase 1A1 Promoters by Hepatocyte Nuclear...
Journal of Pharmacology and Experimental Therapeutics. *Molecular Pharmacology. *Pharmacological Reviews. *Pharmacology ... P.B. was supported by a fellowship from the Association de Recherche sur le Cancer (ARC; Villejuif, France) and the Etat de ... Your Name) has forwarded a page to you from Molecular Pharmacology Message Body (Your Name) thought you would be interested in ... Thank you for sharing this Molecular Pharmacology article.. NOTE: We request your email address only to inform the recipient ...
MIPS Publications | Molecular Imaging Program at Stanford (MIPS) | Stanford Medicine
A New Approach for Predicting Tumor Delivery of Macromolecular Therapeutics? Radiol Imaging Cancer. 2023 Mar;5(2):e220183. doi ... Cancer Immunol Immunother. 2022.. Hu et al. Detection and Characterization of Sentinel Lymph Node by Ultrasound Molecular ... Factors for differential outcome across cancers in clinical molecular-targeted fluorescence imaging. J Nucl Med 2022 Published ... Center for Cancer Nanotechnology Excellence for Translational Diagnostics. EDRN - NIH U01. Early Cancer Detection Research ...
Faculty Research Descriptions | Molecular and Cell Biology
Professor of Molecular Therapeutics. Molecular mechanisms underlying diseases of the retina. Daniel A. Fletcher. Professor ( ... Molecular mechanisms of apoptosis and proliferation in T cells, cancer, host pathogen interaction and human stem cells. ... Professor of Molecular Therapeutics. Understanding and editing the human epigenome for molecular therapeutic development. ... Associate Professor of Molecular Therapeutics. Molecular mechanisms of synapse and circuit plasticity. ...
Cardio-Oncology: The Intersection Between Cancer and Cardiovascular Disease
... sharpening of focus on the cardiovascular risks of patients who have survived cancer or are being treated for cancer, as well ... With the prognosis for many cancers improving, we are seeing an appropriate ... 3. Cheng H, Force T. Molecular mechanisms of cardiovascular toxicity of targeted cancer therapeutics. Circ Res. 2010;106(1):21- ... For many cancers, including breast cancer and lymphoma, chest radiation remains an important component of the treatment regimen ...
Catherine Van Raamsdonk - UBC Associate Professor - Faculty Member - Researcher - Supervisor
Molecular analysis of melanocytes and melanoma cells from mouse models: transcriptomics, bioinformatics, proteomics. Primary ... Therapeutics and signaling pathways in melanoma. Genetic medicine; Health counselling; ... Molecular mechanisms of BAP1 mutations in uveal melanoma (2021). Uveal melanoma (UM), a cancer that arises in the eye, is ... Cancer cell metastasis. Neural crest cell development. Molecular analysis of melanocytes and melanoma cells from mouse models: ...
Research - University of Rochester Medical Center
Investigating Cancer and Improving Care. RNA Biology. The Center for RNA Biology: From Genome to Therapeutics conducts research ... recognized expert in the field of RNA biology in which she works to discover new cellular pathways and clues to the molecular ... Cancer. Thanks to research, cancer patients have advantages that didnt exist 20 years ago-or in some cases, even a few months ... She is the founding director of the Universitys Center for RNA Biology: From Genome to Therapeutics. In 2011 she was elected ...
Fine-tuning Cancer Treatments | MIT Technology Review
Now this genetic knowledge is being used to direct drug development by testing specific compounds on 1,000 cancer cell lines ... uncovering a growing number of genetic mutations that drive cancer. ... The plummeting cost of DNA sequencing has enabled scientists to explore the genetic complexities of cancer with an ever-finer ... "The extent of our genomic characterization is unmatched," says Cyril Benes, director of The Center for Molecular Therapeutics ...
Robert Flavell | UCSF Health
He is chief of molecular imaging and therapeutics for the UCSF Department of Radiology and Biomedical Imaging. ... In research, Flavell focuses on developing new methods of diagnosing and treating cancer using molecular imaging technology, ... BAKAR PRECISION CANCER MEDICINE BUILDING Care, Convenience and Support at New Cancer Facility ... Clinically Translatable Hyperpolarized 13C Bicarbonate pH Imaging Method for Use in Prostate Cancer. ACS sensors ...
Does Cancer Research UK have a flat Organisational structure? - Bristol Cancer Help Centre
The flat structure that cancer research uses is helpful for them achieving their strategic goals because the shareholders ... Does Cancer Research UK have a flat Organisational structure? ... Breast Cancer Research *Cancer Biology *Cancer Therapeutics ... What are the main cancer charities in UK?. Cancer support. *Blood Cancer UK. The UKs specialist blood cancer charity, ... Is Cancer Research UK the biggest charity?. Cancer Research UK is the worlds largest independent cancer research charity, and ...
Relay Therapeutics to Present Clinical Data on RLY-4008 in Advanced FGFR2-Altered Solid Tumors at 2023 AACR-NCI-EORTC...
FGFR2-Altered Solid Tumors at 2023 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. ... will be presented at the upcoming AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, taking ... About Relay Therapeutics. Relay Therapeutics is a clinical-stage precision medicine company transforming the drug discovery ... Relay Therapeutics will host a conference call to discuss these data. Details will be provided at a future date and available ...
Relay Therapeutics to Present Clinical Data on RLY-4008 in Advanced FGFR2-Altered Solid Tumors at 2023 AACR-NCI-EORTC...
FGFR2-Altered Solid Tumors at 2023 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. ... will be presented at the upcoming AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, taking ... About Relay Therapeutics. Relay Therapeutics is a clinical-stage precision medicine company transforming the drug discovery ... Relay Therapeutics will host a conference call to discuss these data. Details will be provided at a future date and available ...
MUC glycoproteins: Potential biomarkers and molecular targets for cancer therapy. - Amrita Vishwa Vidyapeetham
... along with its unique signalling mechanism and role of aberrant glycosylation in cancer progression and therapeutics. The ... endometrial and cervical cancer, lung cancer, primary liver cancer, pancreatic cancer, prostate cancer and ovarian cancer has ... Potential biomarkers and molecular targets for cancer therapy.", Current Cancer Drug Targets, 2021, 21(2), pp. 132-152 ... MUC glycoproteins: Potential biomarkers and molecular targets for cancer therapy.. Publication Type : Journal Article ...