The landscape of RNA polymerase II transcription initiation in C. elegans reveals promoter and enhancer architectures
Molecular Sequence Annotation * Promoter Regions, Genetic* * RNA Polymerase II / metabolism* * Sequence Analysis, DNA ...
ModBase, a database of annotated comparative protein structure models and associated resources
... sequence-structure alignment, model building and model assessment (http:// … ... Models, Molecular* * Molecular Sequence Annotation * Protein Structure, Tertiary * Proteome / chemistry * Scattering, Small ... Department of Molecular Biology, Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA ... ModBase currently contains almost 30 million reliable models for domains in 4.7 million unique protein sequences. ModBase ...
Transcriptional Profiling Uncovers Human Hyalocytes as a Unique Innate Immune Cell Population
Molecular Sequence Annotation * Myeloid Cells / immunology * Myeloid Cells / metabolism * Transcriptome* * Vitreous Body / ... RNA extraction, library preparation and RNA sequencing were performed and the sequencing data was analyzed using the Galaxy web ... RNA sequencing revealed that SPP1, FTL, CD74, and HLA-DRA are among the most abundantly expressed genes in hyalocytes, which ...
The European Variation Archive: a FAIR resource of genomic variation for all species
Molecular Sequence Annotation * Polymorphism, Single Nucleotide / genetics * Software* Grants and funding * 208377/Z/17/Z/WT_/ ... 1 European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. ...
DAVID-WS: a stateful web service to facilitate gene/protein list analysis
Molecular Sequence Annotation * Proteins* * Software Substances * Proteins ... Summary: The database for annotation, visualization and integrated discovery (DAVID), which can be freely accessed at http:// ...
Strains, functions and dynamics in the expanded Human Microbiome Project
... and molecular function. The National Institutes of Health Human Microbiome Project has provided one of the broadest such ... Molecular Sequence Annotation * National Institutes of Health (U.S.) * Organ Specificity * Phylogeny* ... and molecular function. The National Institutes of Health Human Microbiome Project has provided one of the broadest such ...
Smc5 structural maintenance of chromosomes 5 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... enables molecular_function ND No biological Data available. more info. enables nucleotide binding IEA Inferred from Electronic ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 19. NC_000085.7 (23183805.. ... Source sequence(s). AC144941, AJ534941 Consensus CDS. CCDS89364.1 UniProtKB/Swiss-Prot. Q80TW7, Q8CG46, Q8CHX5, Q922K3. Related ...
Improved Genome Assembly and Annotation for the Rock Pigeon ( Columba livia)
... and has recently emerged as a model for understanding the molecular … ... Molecular Sequence Annotation* * Synteny / genetics * Transcriptome / genetics Substances * DNA Transposable Elements * Genetic ... Improved Genome Assembly and Annotation for the Rock Pigeon ( Columba livia) G3 (Bethesda). 2018 May 4;8(5):1391-1398. doi: ... Here we report an update to the C. livia genome reference assembly and gene annotation dataset. Greatly increased scaffold ...
Discovering genes associated with dormancy in the monogonont rotifer Brachionus plicatilis
The 47,926 ESTs expand significantly the current sequence resource of B. plicatilis. It describes, for the first time, genes ... A total of 47,926 sequences were assembled into 18,000 putative transcripts and analyzed using both Blast and GO annotation. ... The aim of this study was to generate Expressed Sequence Tags (ESTs) for molecular characterisation of processes associated ... Conclusion: The 47,926 ESTs expand significantly the current sequence resource of B. plicatilis. It describes, for the first ...
Entrez Help - Entrez Help - NCBI Bookshelf
... search and retrieval system that integrates the PubMed database of biomedical literature with 38 other literature and molecular ... databases including DNA and protein sequence, structure, gene, genome, genetic variation and gene expression. This document is ... large-scale molecular projects including genome sequencing and assembly, transcriptome, metagenomic, annotation, expression and ... Apart from sequence data in the EST (Expressed Sequence Tag) and GSS (Genome Survey Sequence divisions of GenBank, the ...
Bag1 BCL2-associated athanogene 1 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... BAG family molecular chaperone regulator 1. Names. Bcl-2-binding protein. bcl-2-associated athanogene 1. ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 4. NC_000070.7 (40936398.. ... Source sequence(s). AK009149, AK013611, BQ031093, CX225744 Consensus CDS. CCDS51139.1 UniProtKB/Swiss-Prot. Q60739 UniProtKB/ ...
The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies
... we describe the development and disseminate system methods for associating patient genomic sequence data with clinically ... and supports annotation of functional significance of molecular variants. Through queries of data housed in JAX-CKB, we have ... of clinical trials relevant to our 358-gene targeted sequencing panel to evaluate strengths and weaknesses in current molecular ... Results: To support clinical decision-making, we have developed a data loader and mapper that connects sequence information ...
Surviving extreme polar winters by desiccation: clues from Arctic springtail (Onychiurus arcticus) EST libraries
The use of GO annotation for analysis has facilitated the identificatio … ... aim of this project was to generate clones and sequence data in the form of ESTs to provide a platform for the future molecular ... The use of GO annotation for analysis has facilitated the identification of a wide variety of ESTs associated with a number of ... A total of 16,379 EST clones were generated and analysed using Blast and GO annotation. 40% of the clones produced significant ...
MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
2 Howard Hughes Medical Institute and Departments of Molecular Biology and Medicine, Massachusetts General Hospital, Boston, MA ... This catalogue was compiled using a Bayesian integration of multiple sequence features and experimental datasets, notably ... MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations Nucleic Acids Res. ... We now include manually curated annotations of sub-mitochondrial localization (matrix, inner membrane, intermembrane space, ...
CARTPT CART prepropeptide [Homo sapiens (human)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... enables molecular_function ND No biological Data available. more info. enables neuropeptide hormone activity IEA Inferred from ... Annotation release. Status. Assembly. Chr Location. RS_2023_10. current. GRCh38.p14 (GCF_000001405.40). 5. NC_000005.10 ( ... Source sequence(s). AI417979, BC029882 Consensus CDS. CCDS4011.1 UniProtKB/Swiss-Prot. Q16568, Q6FG92. Related. ...
Sav1 salvador family WW domain containing 1 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... enables molecular adaptor activity IBA Inferred from Biological aspect of Ancestor. more info ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 12. NC_000078.7 (70011786.. ... Source sequence(s). AC166827 Consensus CDS. CCDS25956.1 UniProtKB/Swiss-Prot. Q8VEB2, Q9D9N9, Q9ER46. Related. ...
Tasor2 transcription activation suppressor family member 2 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... Molecular Biology Databases *Bgee database. * Tasor2 gene expression *BioGPS. * BioGPS *BioGRID Open Repository of CRISPR ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 13. NC_000079.7 (3615905.. ... Source sequence(s). AC129597 Conserved Domains (2) summary. pfam12480. Location:94 → 167. DUF3699; Protein of unknown function ...
Phtf1 putative homeodomain transcription factor 1 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals. Manuel A, et al. Genomics, 2000 ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 3. NC_000069.7 (103875426.. ... Source sequence(s). AC162922, AK019146, BE948000, BU053202, CO041244 Consensus CDS. CCDS51030.1 UniProtKB/TrEMBL. Q8C2F6 ...
Homology - Site Guide - NCBI
A collection of sequence alignments and profiles representing protein domains conserved in molecular evolution. It also ... The database provides easy access to annotation information, publications, domains, structures, external links, and analysis ... This tool compares nucleotide or protein sequences to genomic sequence databases and calculates the statistical significance of ... Finds regions of local similarity between biological sequences. The program compares nucleotide or protein sequences to ...
NCBI HMM accession TIGR04454
Sequence cutoff Minimum hmmsearch full-sequence score for the protein to be considered a hit to this HMM. ... HMMs and BlastRules also contribute to structural annotation by NCBIs Prokaryotic Genome Annotation Pipeline (PGAP) (Read more ... Gene Ontology (GO) terms: controlled vocabulary that define the function of genes with respect to three categories: molecular ... The number of RefSeq proteins with sequence and domain scores above the HMMs sequence and domain cutoffs, respectively. ...
N4BP2L2 NEDD4 binding protein 2 like 2 [Homo sapiens (human)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... enables molecular_function ND No biological Data available. more info. enables protein binding IPI Inferred from Physical ... Source sequence(s). AL137247, AL353665 Conserved Domains (1) summary. pfam13671. Location:404 → 536. AAA_33; AAA domain. ... Source sequence(s). AL137247, AL353665 Conserved Domains (1) summary. pfam13671. Location:404 → 536. AAA_33; AAA domain. ...
Fbxo5 F-box protein 5 [Mus musculus (house mouse)] - Gene - NCBI
Inferred from Electronic Annotation. more info. enables molecular function inhibitor activity ISO Inferred from Sequence ... These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 10. NC_000076.7 (5749155.. ... Source sequence(s). AC159325, BC053434 Consensus CDS. CCDS56683.1 UniProtKB/Swiss-Prot. Q7TSG3 Related. ENSMUSP00000019907.8, ...
Functional characterization and high-throughput proteomic analysis of interrupted genes in the archaeon Sulfolobus solfataricus
In the past, interrupted genes were generally considered to be the result of sequencing errors or pseudogenes, that is, gene ... Sequenced genomes often reveal interrupted coding sequences that complicate the annotation process and the subsequent ... Sequenced genomes often reveal interrupted coding sequences that complicate the annotation process and the subsequent ... Base Sequence * Chromatography, Liquid * Genes, Archaeal* * High-Throughput Screening Assays / methods* * Molecular Sequence ...
Sdad1 SDA1 domain containing 1 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... Molecular Biology Databases *Bgee database. * Sdad1 gene expression *BioGPS. * BioGPS *BioGRID Open Repository of CRISPR ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 5. NC_000071.7 (92431869.. ... Source sequence(s). AK029881 Consensus CDS. CCDS19429.1 UniProtKB/TrEMBL. A0A0J9YV20, A0A0R4J0B7. Related. ENSMUSP00000031364.2 ...
AceView: gene:dpy-21, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView.
... and nematode genes reconstructed by co-alignment and clustering of all publicly available mRNAs and ESTs on the genome sequence ... AceView offers a comprehensive annotation of human, mouse ... wbg9.1p73] molecular analysis of dosage compensation continues ... sequences, mRNA and protein annotations. Proteins supported by a single continuous cDNA sequence lead to underlining the name/ ... Upstream sequence. Transcription. unit. pre-mRNA. Downstream sequence. a. 5648 bp. 1641 aa. 154 bp. 568 bp. 2kb including ...
AceView: gene:him-8, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView.
... and nematode genes reconstructed by co-alignment and clustering of all publicly available mRNAs and ESTs on the genome sequence ... AceView offers a comprehensive annotation of human, mouse ... wbg10.2p29] molecular cloning of fem-1. *[wbg10.3p18] update on ... sequences, mRNA and protein annotations. Proteins supported by a single continuous cDNA sequence lead to underlining the name/ ... and pointers to all genes with the same functional annotation. To see the mRNA diagram, sequence and annotation, click the ...
Data & Software - Site Guide - NCBI
... complex submissions containing long sequences, multiple annotations, segmented sets of DNA, as well as sequences from ... A set of software and data exchange specifications used by NCBI to produce portable, modular software for molecular biology. ... Sequence Viewer Provides a configurable graphical display of a nucleotide or protein sequence and features that have been ... FTP: Sequence Read Archive (SRA) Download Facility This site contains next-generation sequencing data organized by the ...
Gm19617 predicted gene, 19617 [Mus musculus (house mouse)] - Gene - NCBI
Annotation information. not in current annotation release. NEW Try the new Gene table Try the new Transcript table ... Transcript sequences (FASTA). Protein sequences(FASTA). In addition, your package will include a detailed data report in both ... Molecular Biology Databases *BioGPS. * BioGPS *GenScript latest version of gene cDNA ORF Clone ...
Bacterial and archaeal genomes with GO terms in RefSeq! - NCBI Insights
Molecular Function and Cellular Component ontologies to genomes and proteins we annotate with the Prokaryotic Genome Annotation ... GO terms are now associated with coding sequence (CDS) features on newly-submitted genomes (See Figure 1). They will ... Figure 2: Excerpt from the RefSeq record for KatG protein WP_004180028.1, with Molecular Function GO terms GO:0004096 and GO: ... Figure 1: Excerpt from the RefSeq record for NZ_CP091650.1, a Klebsiella pneumoniae genome, showing the annotation of the the ...
Eeig1 estrogen-induced osteoclastogenesis regulator 1 [Mus musculus (house mouse)] - Gene - NCBI
These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq ... enables molecular_function ND No biological Data available. more info. enables protein binding IPI Inferred from Physical ... Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ- ... Annotation release. Status. Assembly. Chr Location. RS_2023_04. current. GRCm39 (GCF_000001635.27). 2. NC_000068.8 (32425344.. ...