In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasia. Licato, L.L., Keku, T.O., Wurzelmann, J.I ... gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen-activated protein kinase pathway. ... wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary ... and treated animals and DMH-induced intestinal tumors were assayed for JNK and ERK activity using solid phase in vitro kinase ...

The protein stannin binds 14-3-3zeta and modulates mitogen-activated protein kinase signaling. Davidson, C.E., Reese, B.E., ... Protein kinase C epsilon regulates tumor necrosis factor-alpha-induced stannin gene expression. Reese, B.E., Davidson, C., ... Quantitative changes in the synaptic vesicle proteins synapsin I and p38 and the astrocyte-specific protein glial fibrillary ... particularly the phospholipid hydrolysis/protein kinase C pathway, are discussed [11].. *Acute administration of TMT caused ...

Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis ... Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Otterbein, L.E., Bach, F. ... by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. ... Membrane cofactor protein (CD46) protects cells from complement-mediated attack by an intrinsic mechanism. Oglesby, T.J., Allen ...

p38 mitogen-activated protein kinase-dependent and -independent intracellular signal transduction pathways leading to apoptosis ... involvement of translocation and down regulation of protein kinase C. Kitajima, Y., Inoue, S., Nagao, S., Nagata, K., Yaoita, H ... Involvement of ERK AND p38 MAP kinase in AAPH-induced COX-2 expression in HaCaT cells. Cui, Y., Kim, D.S., Park, S.H., Yoon, J. ... Neurocalcin: a novel calcium-binding protein from bovine brain. Terasawa, M., Nakano, A., Kobayashi, R., Hidaka, H. J. Biol. ...

... induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases. ... Therefore, pertussis toxin-sensitive Gi-proteins, protein kinase C, tyrosine kinase, phosphatidylinositol-3-kinase and ... Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein ... Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin. Uguccioni, M., ...

Progestin and G protein-coupled receptor 30 inhibit mitogen-activated protein kinase activity in MCF-7 breast cancer cells. ... wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary ... knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound ... 2 activities verified by immunoblotting and kinase assay [33]. ...

... a mitogen-activated protein (MAP) kinase identified in the African trypanosome, Trypanosoma brucei, is a serine protein kinase ... Interferon-gamma activation of a mitogen-activated protein kinase, KFR1, in the bloodstream form of Trypanosoma brucei. Hua, S. ... The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Allen, J.B., Zhou, Z ... Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway. ...

Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation ... After treatment with heparitinase, the protein was reduced in molecular mass by 120 kDa to a protein core of 180 kDa [36]. ... Identification of a novel cortactin SH3 domain-binding protein and its localization to growth cones of cultured neurons. Du, Y ... DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2. Taagepera, ...

Although SHP-2 regulates mitogen-activated protein kinase activity, the mitogen-activated protein kinase kinase inhibitor PD- ... Protein-tyrosine-phosphatase 2C is phosphorylated and inhibited by 44-kDa mitogen-activated protein kinase. Peraldi, P., Zhao, ... Protein-tyrosine-phosphatase 2C is phosphorylated and inhibited by 44-kDa mitogen-activated protein kinase [37]. ... Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation ...

... was modulated by inhibitors of protein kinase C and Erk mitogen-activated protein (MAP) kinase [27]. ... Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein ... Increased expression of cyclooxygenase-2 protein in 4-nitroquinoline-1-oxide-induced rat tongue carcinomas and chemopreventive ... Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein. Avramovich, Y., Amit, T., ...

... cyclooxygenase-2 in antigen-stimulated mast cells is associated with minimal activation of p38 mitogen-activated protein kinase ... G-protein beta gamma-subunits activate the cardiac muscarinic K+-channel via phospholipase A2. Kim, D., Lewis, D.L., Graziadei ... 24R,25-(OH)(2)D(3) mediates its membrane receptor-dependent effects on protein kinase C and alkaline phosphatase via ... Potent ulcerogenic actions of platelet-activating factor on the stomach. Rosam, A.C., Wallace, J.L., Whittle, B.J. Nature (1986 ...

... and this pathway is separate from protein kinase A (PKA)-dependent CREB activation or p38 mitogen-activated protein kinase (p38 ... Involvement of p38 mitogen-activated protein kinase signaling pathway in the rapid induction of the 78-kDa glucose-regulated ... Activation of p38 mitogen-activated protein kinase and mitochondrial Ca(2+)-mediated oxidative stress are essential for the ... Activation of p38 mitogen-activated protein kinase and mitochondrial Ca(2+)-mediated oxidative stress are essential for the ...

Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2. ... Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2 ... which is a protein kinase C substrate and colocalizing protein, and with an inhibitor of protein kinase C, hPKCI-1 [15]. ... The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and ...

MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase ... MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase ... Differing roles for platelet-activating factor during inflammation of the lung and subarachnoid space. The special case of ... Immunogenicity of a Haemophilus influenzae polysaccharide-Neisseria meningitidis outer membrane protein complex conjugate ...

... potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activated protein kinase. ... ATP receptor regulation of adenylate cyclase and protein kinase C activity in cultured renal LLC-PK1 cells. Anderson, R.J., ... ATP receptor regulation of adenylate cyclase and protein kinase C activity in cultured renal LLC-PK1 cells [8]. ... Here we have shown that G(i/o) protein-coupled A1 adenosine receptor (A1R) and Gq protein-coupled P2Y1 receptor (P2Y1R) ...

Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal ... Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological ... Phosphorylation of eIF-4F by protein kinase C or multipotential S6 kinase stimulates protein synthesis at initiation. Morley, S ... Neuronal Cdc2-like protein kinase (Cdk5/p25) is associated with protein phosphatase 1 and phosphorylates inhibitor-2. Agarwal- ...

Phosphorylation of mitogen-activated protein kinase is increased after treatment of cells with ghrelin. Ghrelin binding ... wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary ... is significantly inhibited as demonstrated by decrease of peroxisome proliferator-activator receptor-gamma mRNA and protein. ... knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound ...

In further experiments, we show that the level of mitogen-activated protein kinase (MAPK) activation is polarized along the ... wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary ... animal/vegetal axis, with the Xnr2- expressing cells in the vegetal marginal zone having no detectable activated MAPK. We show ... knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound ...

Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP- ... PLB can be phosphorylated at Ser16 by cAMP-dependent protein kinase (PKA) and Thr17 by Ca2+-calmodulin-dependent protein kinase ... Recently, it was reported that calcitonin receptors were coupled to both cAMP-dependent protein kinase (PKA) and protein kinase ... Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1. ...

Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor ... Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor. Hsueh, W., ... Thromboxane (Tx) A2 is a platelet agonist, smooth muscle cell constrictor, and mitogen [23]. ... wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary ...

... the ability of insulin to activate protein kinase B (ie, the phosphorylated protein kinase B [pPKB]-protein kinase B ratio) was ... BACKGROUND: Insulin-like growth factor-I (IGF-I) is a potent mitogen for normal and neoplastic cells, whereas IGF-binding ... PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase. Sancak, Y., Thoreen, C.C., Peterson, T.R., Lindquist, R. ... Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China. London, S.J ...

Import of a DHFR hybrid protein into glycosomes in vivo is not inhibited by the folate-analogue aminopterin. Häusler, T., ... Ecto-5-nucleotidase can provide the total purine requirements of mitogen-stimulated human T cells and rapidly dividing human B ... Human T cell hybrids were generated by fusing lectin-activated normal and leukemic human T cells with an aminopterin-sensitive ... which is aminopterin sensitive due to a deficiency in the enzyme thymidine kinase [33]. ...