Adenine Nucleotide Translocator 1
     Summary Report | CureHunterAdenine Nucleotide Translocator 1 Summary Report | CureHunter

ATP translocase found primarily in heart muscle (MYOCARDIUM) and skeletal muscle (MUSCLE, SKELETAL). ... Mitochondrial Proteins: 885*Mitochondrial Membrane Transport Proteins: 1*ATP Translocases Mitochondrial ADP: 95*Adenine ... A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM) and skeletal muscle (MUSCLE, ... the latter was evidenced by mitochondrial membrane potential (MPP) reduction and mitochondrial complexation between cyclophilin ...
more infohttp://www.curehunter.com/public/keywordSummaryD033741-Adenine-Nucleotide-Translocator-1.do

Nucleoside diphosphate kinase, mitochondrialNucleoside diphosphate kinase, mitochondrial

... space by its activity is directly taken up via ANT ADP/ATP translocase into the matrix space to stimulate respiratory ATP ... ATP + ADP = ADP + ATP ( Purine nucleotides and Nucleosides metabolism ) 7 ATP + CDP = ADP + CTP ( Pyrimidine Nucleotides and ... ATP + GDP = ADP + GTP ( Purine nucleotides and Nucleosides metabolism ) 7 ATP + IDP = ADP + ITP ( Purine nucleotides and ... ATP + UDP = ADP + UTP ( Pyrimidine Nucleotides and Nucleosides metabolism ) 7 ATP + dADP = ADP + dATP ( Purine nucleotides and ...
more infohttps://pharos.nih.gov/idg/targets/O00746

Mitochondrial ADP, ATP Translocases - RightDiagnosis.comMitochondrial ADP, ATP Translocases - RightDiagnosis.com

ATP Translocases information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Mitochondrial ADP, ATP Translocases. Description of Mitochondrial ADP, ATP Translocases. Mitochondrial ADP, ATP Translocases: A ... ATP Terms associated with Mitochondrial ADP, ATP Translocases:. Terms Similar to Mitochondrial ADP, ATP Translocases:. *ADP,ATP ... ADP,ATP Translocator Protein *Adenine Nucleotide Translocase Source - MeSH 2007 More specific terms for Mitochondrial ADP, ATP ...
more infohttps://www.rightdiagnosis.com/medical/mitochondrial_adp_atp_translocases.htm

Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable,...Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable,...

ATP synthase (F1Fo-ATPase), and ADP/ATP translocase. AppCCl2p is shown to inhibit the ADP/ATP translocase in the mitochondrial ... This is discharged by the ATP synthase and ADP/ATP translocator and converted to ATP energy. D, inhibition of ADP/ATP ... adenine nucleotide translocase (ADP/ATP translocase). AppCp. adenosine-[5′-β,γ-methylene]triphosphate. PT. (mitochondrial) ... the ADP/ATP translocase, and the Pi translocase in the mitochondrial inner membrane. Therefore, the potential inhibitory ...
more infohttp://molpharm.aspetjournals.org/content/61/5/1255

Mapping multiple potential ATP binding sites on the matrix side of the bovine ADP/ATP carrier by the combined use of MD...Mapping multiple potential ATP binding sites on the matrix side of the bovine ADP/ATP carrier by the combined use of MD...

ADP/ATP) carrier-AAC-was crystallized in complex with its specific inhibitor carboxyatractyloside (CATR). The protein consists ... Mitochondrial ADP, ATP Translocases / chemistry*. Molecular Dynamics Simulation*. Protein Binding. Protein Structure, Tertiary ... The mitochondrial adenosine diphosphate/adenosine triphosphate (ADP/ATP) carrier-AAC-was crystallized in complex with its ... Mapping multiple potential ATP binding sites on the matrix side of the bovine ADP/ATP carrier by the combined use of MD ...
more infohttp://www.biomedsearch.com/nih/Mapping-multiple-potential-ATP-binding/21989959.html

Inner versus outer MMP. (A) Respirometry performed afte | Open-iInner versus outer MMP. (A) Respirometry performed afte | Open-i

Mitochondrial ADP, ATP Translocases/metabolism*. *Proto-Oncogene Proteins c-bcl-2/metabolism* ... Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR ... Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR ... 5 A, trace b). Moreover, addition of ADP (the physiological substrate of ANT) strongly inhibited the Vpr-dependent, NADH- ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC2195906_JEM001532.f5ab&req=4

SLC25A4 - WikipediaSLC25A4 - Wikipedia

"DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase". Journal of Molecular Biology. 206 (2 ... ADP/ATP translocase 1 is an enzyme that in humans is encoded by the SLC25A4 gene or adenine nucleotide translocator, ANT. ... Houldsworth J, Attardi G (Jan 1988). "Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human ... Neckelmann N, Li K, Wade RP, Shuster R, Wallace DC (Nov 1987). "cDNA sequence of a human skeletal muscle ADP/ATP translocator: ...
more infohttps://en.wikipedia.org/wiki/SLC25A4

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress | JEMReticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress | JEM

Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase. Int. J. Biochem. Cell Biol. 41:1371 ... where it is required to generate ADP. This, in turn, serves as substrate for the ATP synthase and fuels the mitochondrial ATP ... We reasoned that the reduced ADP recycling caused by AK2 deficiency would result in decreased ATP production, mitochondrial ... The decrease in cellular ADP observed in AK2-mutated iPSCs is expected to have a major impact on the activity of the ATP ...
more infohttp://jem.rupress.org/content/early/2015/06/30/jem.20141286

Nitrogen Generator at Thomas ScientificNitrogen Generator at Thomas Scientific

ATP analog that inhibits mitochondrial ADP/ATP translocase and prevents mitochondrial oxygen consumption… ...
more infohttps://www.thomassci.com/scientific-supplies/Nitrogen-Generator

Bisphosphonates: Mode of Action and Pharmacology | SUPPLEMENT ARTICLES | PediatricsBisphosphonates: Mode of Action and Pharmacology | SUPPLEMENT ARTICLES | Pediatrics

Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable ... possibly by interference with mitochondrial ATP translocases.64 Overall, this group of bisphosphonates, therefore, seem to act ... ATP) that may inhibit ATP-dependent intracellular enzymes. In contrast, the more potent, nitrogen-containing bisphosphonates ( ... PPi-inorganic pyrophosphate • ATP-adenosine triphosphate • FPP-farnesyl diphosphate • GGPP-geranylgeranyl diphosphate • FPPS- ...
more infohttp://pediatrics.aappublications.org/content/119/Supplement_2/S150

Bisphosphonates for Cancer Research | Sigma-AldrichBisphosphonates for Cancer Research | Sigma-Aldrich

Lehenkari, P.P, et al., Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase ... They are metabolized to form cytotoxic ATP-analogs that accumulate intracellularly in osteoclasts and induce apoptosis.1,2 ...
more infohttps://www.sigmaaldrich.com/life-science/cell-biology/cancer-research/product-highlights/bisphosphonates.html

Bisphosphonates for Cancer Research | China-Mainland | Sigma-AldrichBisphosphonates for Cancer Research | China-Mainland | Sigma-Aldrich

Lehenkari, P.P, et al., Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase ... They are metabolized to form cytotoxic ATP-analogs that accumulate intracellularly in osteoclasts and induce apoptosis.1,2 ...
more infohttps://www.sigmaaldrich.com/china-mainland/zh/life-science/cell-biology/cancer-research/product-highlights/bisphosphonates.html

Energetics of muscular exercise | SpringerLinkEnergetics of muscular exercise | SpringerLink

The functional coupling between mitochondrial creatine phosphokinase and ATP-ADP translocase: kinetic evidence. Arch Biochem ... Karlsson J, Saltin B (1970) Lactate, ATP and CP in working muscles during exhaustive exercise in man. J Appl Physiol 29:598-602 ... Chance B, Mauriello G, Aubert X (1962) ADP arrival at muscle mitochondria following a twitch. In: Rodahl K, Horvath SM (eds) ... Saltin B, Essén B (1971) Muscle glycogen lactate, ATP and CP in intermittant exercise. In: Pernow B, Saltin B (eds) Muscle ...
more infohttps://link.springer.com/chapter/10.1007%2FBFb0035266

Comment on Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry | ScienceComment on "Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry" | Science

Altered chromatographic behaviour of mitochondrial ADP/ATP translocase induced by stabilization of the protein by binding of 6 ... The molecular mechanism of transport by the mitochondrial ADP/ATP carrier. Cell 176, 435-447.e15 (2019). doi:10.1016/j.cell. ... Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism. Proc. Natl. ... Complete amino acid sequence of the ADP/ATP carrier from beef heart mitochondria. Hoppe Seylers Z. Physiol. Chem. 363, 345-349 ...
more infohttps://science.sciencemag.org/content/366/6466/eaaw9830

Immunological and Enzymatic Approaches of the Orientation of the Membrane Bound ADP/ATP Carrier | Springer for Research &...Immunological and Enzymatic Approaches of the Orientation of the Membrane Bound ADP/ATP Carrier | Springer for Research &...

Saraste M, Walker JE (1982) Internal sequence repeats and the path of polypeptide in mitochondrial ADP/ATP translocase. FEBS ... Klingenberg M (1985) The ADP/ATP carrier in mitochondrial membranes. In: Martonosi AN (ed) The Enzymes of Biological Membranes ... structural relationship to ADP/ATP translocase and tne brown fat mitochondria uncoupling protein. EMBO J 6:1367-1373PubMed ... Iodination of peripheral mitochondrial membrane proteins in correlation to the functional state of the ADP/ATP carrier. Biochem ...
more infohttps://rd.springer.com/chapter/10.1007/978-3-642-74539-3_12

The basal proton conductance of mitochondria depends on adenine nucleotide translocase contentThe basal proton conductance of mitochondria depends on adenine nucleotide translocase content

Mitochondrial ADP, ATP Translocases (MeSH) * Phospholipids (MeSH) * Protein Binding (MeSH) * Protons (MeSH) ... independently of its ATP/ADP exchange or fatty-acid-dependent proton-leak functions. ... The basal proton conductance of mitochondria depends on adenine nucleotide translocase content Academic Article * Authors ... We show that the proton conductance of muscle mitochondria from mice in which isoform 1 of the adenine nucleotide translocase ...
more infohttps://scholars.latrobe.edu.au/display/publication78675

Ádám-Vizi, V.<...Ádám-Vizi, V.<...

ATP Translocases Mitochondrial ADP Artemia Membrane Proteins Yeasts Mitochondrial Membranes 2 Citations (Scopus) ... Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia- ...
more infohttps://hungary.pure.elsevier.com/hu/persons/v-%C3%A1d%C3%A1m-vizi

Effects of carnitine and atractyloside on canine cardiac electrical activity.<...Effects of carnitine and atractyloside on canine cardiac electrical activity.<...

ATP Translocases Mitochondrial ADP Thorax Perfusion Sodium Dogs ASJC Scopus subject areas. *Medicine(all) ... electrophysiological changes following coronary artery occlusion result from inhibition of the adenine nucleotide translocase ... electrophysiological changes following coronary artery occlusion result from inhibition of the adenine nucleotide translocase ... electrophysiological changes following coronary artery occlusion result from inhibition of the adenine nucleotide translocase ...
more infohttps://indiana.pure.elsevier.com/en/publications/effects-of-carnitine-and-atractyloside-on-canine-cardiac-electric-2

SNUH Internal Medicine - Research Output
     - Seoul National University College of MedicineSNUH Internal Medicine - Research Output - Seoul National University College of Medicine

Adenine Nucleotide Translocase 2 as an Enzyme Related to [18F] FDG Accumulation in Various Cancers. Lee, C. H., Kim, M. J., Lee ...
more infohttps://snucm.elsevierpure.com/en/organisations/snuh-internal-medicine/publications/

Ádám-Vizi, V.<...Ádám-Vizi, V.<...

Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia- ... ATP Translocases Mitochondrial ADP Artemia Membrane Proteins Yeasts Mitochondrial Membranes Reduction of 2-methoxy-1,4- ...
more infohttps://hungary.pure.elsevier.com/en/persons/v-%C3%A1d%C3%A1m-vizi

1985-19891985-1989

Specific inhibition of ATP-ADP translocase in cardiac mitoplasts by antibodies against mitochondrial creatine kinase. Posted by ... Saks VA, Khuchua ZA, Kuznetsov AVBiochim Biophys Acta 1987 Apr 891:138-44Abstract Mitochondrial creatine kinase was purified ...
more infohttp://www.gallusimmunotech.com/years/categories/listings/1985-1989.html

List of MeSH codes (D12.776.157) - WikipediaList of MeSH codes (D12.776.157) - Wikipedia

... mitochondrial adp, atp translocases MeSH D12.776.157.530.625.875.500.100 -- adenine nucleotide translocator 1 MeSH D12.776. ... adp-ribosylation factors MeSH D12.776.157.325.515.100.100 -- adp-ribosylation factor 1 MeSH D12.776.157.325.515.400 -- rab gtp- ... atp-dependent MeSH D12.776.157.530.450.074.500.500.500 -- multidrug resistance-associated proteins MeSH D12.776.157.530.450.074 ... mitochondrial proton-translocating atpases MeSH D12.776.157.530.450.250.875.500.875 -- vacuolar proton-translocating atpases ...
more infohttps://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.157)

Vetmeduni Vienna : Physiologie und Biophysik : BiophysicsVetmeduni Vienna : Physiologie und Biophysik : Biophysics

Our stand-alone project ATP / ADP Translocase and Mitochondrial Proton Leak was approved on May 7, 2018 by the FWF under the ... February 28th, 2017 our 19th Workshop took place, having Unmasking regulation and the role of mitochondrial uncoupling ... In march 2019 the article Glutamine regulates mitochondrial uncoupling protein 2 to promote glutaminolysis in neuroblastoma ... Molecular mechanisms responsible for the dual pharmacological effect of genipin on mitochondrial proteins is being published ...
more infohttps://www.vetmeduni.ac.at/en/biophysics/

TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors |...TGF-β1 induction of the adenine nucleotide translocator 1 in astrocytes occurs through Smads and Sp1 transcription factors |...

... is an inner mitochondrial membrane protein involved with energy mobilization during oxidative phosphorylation. We recently ... Cozens AL, Runswick MJ, Walker JE: DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. J ... Powell SJ, Medd SM, Runswick MJ, Walker JE: Two bovine genes for mitochondrial ADP/ATP translocase expressed differences in ... Ant1 is a major mitochondrial inner membrane protein that exchanges mitochondrial ATP for cytosolic ADP and is thereby an ...
more infohttps://bmcneurosci.biomedcentral.com/articles/10.1186/1471-2202-5-1

Publications | MRC Mitochondrial Biology UnitPublications | MRC Mitochondrial Biology Unit

Filters: Keyword is Mitochondrial ADP, ATP Translocases [Clear All Filters]. 2015. Crichton PG, Lee Y, Ruprecht JJ, Cerson E, ... The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes. Proc Natl Acad Sci U S A 104, 10830- ... Bamber L, Harding M, P Butler JG & Kunji ERS (2006) Yeast mitochondrial ADP/ATP carriers are monomeric in detergents. Proc Natl ... Bamber L, Slotboom D-J & Kunji ERS (2007) Yeast mitochondrial ADP/ATP carriers are monomeric in detergents as demonstrated by ...
more infohttp://www.mrc-mbu.cam.ac.uk/biblio?f%5Bkeyword%5D=85