Khz (fusion of ganoderma lucidum and Polyporus umbellatus mycelia) induces apoptosis in A549 human lung cancer cells by...
Khz cytotoxicity was measured using an MTT assay and the mitochondrial membrane potential (MMP)-related, calcium-induced ... apoptosis in A549 human lung cancer cells by generating reactive oxygen species and decreasing the mitochondrial membrane ... apoptosis in A549 human lung cancer cells by generating reactive oxygen species and decreasing the mitochondrial membrane ... Different regulation of plasma membrane- and granule-localized NADPHoxidase. J. Leukocyte Biol. 71: 611-617 (2002) ...
Therapeutic importance of sulfated polysaccharides from seaweeds: updating the recent findings | 3 Biotech
... and altered mitochondrial membrane permeability. Buthionine-[R,S]-sulfoximine rendered HL-60 cells more sensitive to fucoidan. ... results suggested that the SP play crucial role in stabilizing the functional status of mitochondrial and microsomal membrane ... 2009) studied the liver mitochondrial and microsomal fraction from rats to evaluate the antioxidative effect of oral gavaging ... 2011). Supercritical CO2 extraction, ultrasonic-aid extraction and membrane separation technology may be applied to harvest SP ...
Cellular stress response mechanisms of Rhizoma coptidis: a systematic review | Chinese Medicine
Rhizoma coptidis regulates the NF-κB pathways as follows: (A) inhibition of the activity of membrane receptors, including TLR4 ... Berberine could inhibit thyroid carcinoma cells by inducing mitochondrial apoptosis, G0/G1 cell cycle arrest and suppressing ... Excessive levels of ROS/RNS directly destruct of cell membrane, DNA and proteins, resulting in cell function damage, ... Adenosine monophosphate-activated protein kinase modulation by berberine attenuates mitochondrial deficits and redox imbalance ...
Discovery of a novel cytoplasmic male-sterility and its restorer lines in radish (Raphanus sativus L.) | Theoretical and...
... associated orf138 is translated into a mitochondrial membrane polypeptide in male-sterile Brassica cybrids. Mol Gen Genet 243: ... Sakai T, Imamura J (1993) Evidence for a mitochondrial sub-genome containing radish atpA in a Brassica napus cybrid. Plant Sci ... Kim S, Lim H, Park S, Cho K, Sung S, Oh D, Kim K (2007) Identification of a novel mitochondrial genome type and development of ... Bonhomme S, Budar F, Ferault M, Pelletier G (1991) A 2.5 kb Nco I fragment of Ogura radish mitochondrial DNA is correlated with ...
Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues | Diabetologia
The new vessel is stabilised by the production of ECM components, forming the basement membrane, and the recruitment of ... dissipation of energy in the form of heat mediated by mitochondrial uncoupling protein-1 (UCP-1) activation. UCP-1-expressing ... collagen III and fibronectin replaced by the basement membrane, a specialised ECM surrounding mature adipocytes composed of ... modulates the expression and activity of adrenergic signalling molecules and PGC1α coordinates expression of both mitochondrial ...
Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors | SpringerLink
In D. E. Vance & J. E. Vance (Eds.), Biochemistry of lipids, lipoproteins and membranes (pp. 341-372). New York: Elsevier, ... Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction. Lipids in ... Murphy, M. G. (1990). Dietary fatty acids and membrane protein function. The Journal of Nutritional Biochemistry, 1(2), 68-79. ... Calderón, R. O., & Eynard, A. R. (2000). Fatty acids specifically related to the anisotropic properties of plasma membrane from ...
Science-based policy: targeted nutrition for all ages and the role of bioactives | European Journal of Nutrition
Docosahexaenoic acid (DHA) is an omega-3 fatty acid found in the membrane of all cells, but it is found in particularly high ... circulating mitochondrial DNA, cytokines, etc. While research progresses, it is important to reiterate the message that ... and established that the red blood cell membrane could be a biomarker (or status indicator) for DHA intake [90]. DHA and ARA ... results in increased proportions of those fatty acids in cell membranes, including those of inflammatory cells [82]. The ...
Intake of copper has no effect on cognition in patients with mild Alzheimer's disease: a pilot phase 2 clinical trial | Journal...
... blood count included liver enzymes and anti-mitochondrial antibodies (for exclusion of cholestatic liver diseases). Atomic ... finding could be explained by the finding that clioquinol mediates Cu uptake by transporting Cu across cell membranes ...
Lactate | Sports Medicine
Role of mitochondrial lactic dehydrogenase and lactate oxidation in the intracellular lactate shuttle. Proc Natl Acad Sci U S ... Colocalization of MCT1, CD147 and LDH in nutochondrial inner membrane of L6 cells: evidence of a nutochondrial lactate ... Lactate flux occurs down proton and concentration gradients that are established by the mitochondrial lactate oxidation complex ...
Proton Motive Force | SpringerLink
Proton motive force (PMF) is the force that promotes movement of protons across membranes downhill the electrochemical ... Papa S, Lorusso M, Di Paola M (2006) Cooperativity and flexibility of the protonmotive activity of mitochondrial respiratory ... A difference of solute concentration between two compartments separated by a biological membrane generates a tendency to ...
A New Hope for a Devastating Disease: Hydrogen Sulfide in Parkinson's Disease | SpringerLink
Allicin protects PC12 cells against 6-OHDA-induced oxidative stress and mitochondrial dysfunction via regulating mitochondrial ... Mathai JC, Missner A, Kugler P, Saparov SM, Zeidel ML, Lee JK, Pohl P (2009) No facilitator required for membrane transport of ... Teng H, Wu B, Zhao K, Yang G, Wu L, Wang R (2013) Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase ... Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443(7113):787-795 ...
Membrane Protein Production in Lactococcus lactis for Functional Studies | SpringerLink
... expression and study of membrane proteins in heterologous systems remains difficult. Among the bacterial systems available, the ... Palmieri F (2014) Mitochondrial transporters of the SLC25 family and associated diseases: a review. J Inherit Metab Dis 37:565- ... recent developments in functional expression of membrane proteins. In: Mus-Veteau I (ed) Membrane proteins production for ... Seigneurin-Berny, D. et al. (2016). Membrane Protein Production in Lactococcus lactis for Functional Studies. In: Mus-Veteau, I ...
Urinary metabolites of the UV filter octocrylene in humans as biomarkers of exposure | Archives of Toxicology
Rodil R, Schrader S, Moeder M (2009) Non-porous membrane-assisted liquid-liquid extraction of UV filter compounds from water ... that octocrylene accumulates in Pocillopora damicornis tissues as fatty acid conjugates and triggers coral cell mitochondrial ...
The Gut-Eye Axis: Lessons Learned from Murine Models | Ophthalmology and Therapy
found that variants in two mitochondrial DNA (mtDNA) haplogroups, L2a1 (m.15784T,C) and L2 haplogroups (m.16390G,A), were ... and Bruchs membrane, type 2-between the retina and RPE, or a combination of both (combined pattern) [62]. Using a murine model ... Association of primary open-angle glaucoma with mitochondrial variants and haplogroups common in African Americans. Mol Vis. ... Diabetic retinal neurodegeneration is associated with mitochondrial oxidative stress and is improved by an angiotensin receptor ...
Backbone and side chain resonance assignment of the intrinsically disordered human DBNDD1 protein | Biomolecular NMR Assignments
Their amino acid sequences suggest that they are mainly cytosolic or nuclear proteins partly associating with membranes (Talbot ... A53T-SNCA mice suggests altered mitochondrial biogenesis. Parkinsons Dis. https://doi.org/10.1155/2016/4686185 ...
Splenic Ly6Chi monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient...
... in blocking buffer and membranes were incubated overnight at 4 °C. On the following day, membranes were washed 5 times for 5 ... These beneficial effects were at least partially mediated by CO-dependent inhibition of mitochondrial permeability transition ... Membranes were blocked with 5% bovine serum albumin (BSA) in PBS containing 0.05% Tween-20 (collagen type I) or 5% milk in PBS ... was added for 5 min and membranes were developed on photographic membranes. ...
Neuronal Basis of Non-Invasive Functional Imaging: From Microscopic Neurovascular Dynamics to BOLD fMRI | SpringerLink
Cohen LB, Lesher S (1986) Optical monitoring of membrane potential: methods of multisite optical measurement. Soc Gen Physiol ... network activity in the hippocampus are highly sensitive to decreases in pO2 and concomitant changes in mitochondrial redox ...
RETRACTED ARTICLE: Botanical Pesticides and Their Mode of Action | SpringerLink
Hollingworth R, Ahmmadsahib K, Gedelhak G, McLaughlin J (1994) Newinhibitors of complex I of the mitochondrial electron ... Delphinium alkaloids as inhibitors of alpha-bungarotoxin binding to rat and insect neural membranes. Can J Physiol & Pharmacol ...
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity | Acta...
... accumulation and mitochondrial dysfunction have been implicated in the pathology of Parkinsons disease (PD). Altho ... mitochondrial inner membrane (IMM), outer membrane (OMM), and mitochondria-associated ER membrane (MAM) [23, 32, 50, 90]. αSyn ... 1b). After removing mitochondrial outer membrane by incubation of the mitochondrial fractions with proteinase K, we further ... mitochondrial protein translation, mitochondrial genome stability, and metabolism [30, 67]. Two mitochondrial proteases that ...