Motors and MAPs collaborate to size up microtubules
2013) describe how the motor protein kinesin-4 and the microtubule-associated protein PRC1 work together to mark microtubule ... Midzone microtubules keep chromosomes apart after segregation and provide a platform for cytokinesis factors. Reporting ... 2013) describe how the motor protein kinesin-4 and the microtubule-associated protein PRC1 work together to mark microtubule ... Motors and MAPs collaborate to size up microtubules Dev Cell. 2013 Jul 29;26(2):118-20. doi: 10.1016/j.devcel.2013.07.010. ...
Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses
... J Cell Biol. 2012 Sep 17;198(6): ...
The kinesin-8 Kif18A dampens microtubule plus-end dynamics
... but a rare subset of kinesins are also able to alter microtubule dynamics. At kinetochore-microtubule plus ends, the kinesin-8 ... but a rare subset of kinesins are also able to alter microtubule dynamics. At kinetochore-microtubule plus ends, the kinesin-8 ... The kinesin-8 Kif18A dampens microtubule plus-end dynamics Curr Biol. 2010 Feb 23;20(4):374-80. doi: 10.1016/j.cub.2009.12.049 ... We report here that Kif18A is a plus-end-directed motor that inhibits the polymerization dynamics of microtubule plus ends ...
![KIF27 kinesin family member 27 [Homo sapiens (human)] - Gene - NCBI](data:image/png;base64,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)
KIF27 kinesin family member 27 [Homo sapiens (human)] - Gene - NCBI
involved_in microtubule-based movement IBA Inferred from Biological aspect of Ancestor. more info ... enables microtubule motor activity IBA Inferred from Biological aspect of Ancestor. more info ... is_active_in microtubule IBA Inferred from Biological aspect of Ancestor. more info ... Kinesins and protein kinases: key players in the regulation of microtubule dynamics and organization. Daire V, et al. Arch ...
Tubgcp5 tubulin, gamma complex component 5 [Mus musculus (house mouse)] - Gene - NCBI
Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule ... Microtubule nucleation by γ-tubulin complexes. Kollman JM, et al. Nat Rev Mol Cell Biol, 2011 Oct 12. PMID 21993292, Free PMC ... contributes_to microtubule minus-end binding IBA Inferred from Biological aspect of Ancestor. more info ... involved_in cytoplasmic microtubule organization IBA Inferred from Biological aspect of Ancestor. more info ...
Drg1 developmentally regulated GTP binding protein 1 [Mus musculus (house mouse)] - Gene - NCBI
involved_in positive regulation of microtubule polymerization ISO Inferred from Sequence Orthology. more info ... Predicted to be involved in cytoplasmic translation; positive regulation of microtubule polymerization; and regulation of ...
CSPP1 centrosome and spindle pole associated protein 1 [Homo sapiens (human)] - Gene - NCBI
CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side. van den Berg CM, et al. J Cell Biol, 2023 ... CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side. Title: CSPP1 stabilizes growing ... Microtubule-independent but desmoplakin-dependent localization of CSPP-L to desmosomes occurs in apical-basal polarized ... propose that CSPP1 cooperates with CENP-H on kinetochores to serve as a novel regulator of kinetochore microtubule dynamics for ...
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection
Microtubule-Associated Proteins / genetics * Microtubule-Associated Proteins / metabolism * Mycobacterium / drug effects * ...
PRKCI protein kinase C iota [Homo sapiens (human)] - Gene - NCBI
... and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL- ...
CALM1 calmodulin 1 [Homo sapiens (human)] - Gene - NCBI
located_in spindle microtubule IDA Inferred from Direct Assay. more info. PubMed ...
MFN2 mitofusin 2 [Homo sapiens (human)] - Gene - NCBI
located_in microtubule cytoskeleton IEA Inferred from Electronic Annotation. more info. is_active_in mitochondrial outer ...
Turn Up the Volume: Uncovering Nucleus Size Control Mechanisms
Microtubules / metabolism* * Nuclear Envelope / physiology* * Oocytes / cytology* * Oocytes / metabolism* * Xenopus laevis / ...
SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules
The lumenal surfaces of each microtubule within this diverse array are decorated by microtubule inner proteins (MIPs). Here, we ... The lumenal surfaces of each microtubule within this diverse array are decorated by microtubule inner proteins (MIPs). Here, we ... the doublet microtubules of multiciliated respiratory cells and the distal singlet microtubules of monoflagellated human ... SPACA9 is a lumenal protein of human ciliary singlet and doublet microtubules Proc Natl Acad Sci U S A. 2022 Oct 11;119(41): ...
A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway
Microtubule-Associated Proteins / genetics * Microtubule-Associated Proteins / metabolism * Ovary / physiology* * Peptide ...
Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection
Microtubule-Associated Proteins / deficiency * Microtubule-Associated Proteins / metabolism* * Mycobacterium tuberculosis* / ...
Toward the function of mammalian ATG12-ATG5-ATG16L1 complex in autophagy and related processes
Microtubule-Associated Proteins ...
Quinolinic acid induces neuritogenesis in SH-SY5Y neuroblastoma cells independently of NMDA receptor activation
Microtubule-Associated Proteins / metabolism * NADPH Oxidases / antagonists & inhibitors * Neurites / drug effects* * Neurites ...
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
Microtubule-Associated Proteins / deficiency * Mucus * NF-E2-Related Factor 2 / deficiency * NF-E2-Related Factor 2 / ...
MAPRE3 microtubule associated protein RP/EB family member 3 [Homo sapiens (human)] - Gene - NCBI
MAPRE3 microtubule associated protein RP/EB family member 3 [Homo sapiens] MAPRE3 microtubule associated protein RP/EB family ... microtubule associated protein RP/EB family member 3provided by HGNC. Primary source. HGNC:HGNC:6892 See related. Ensembl: ... microtubule-associated protein RP/EB family member 3. Names. APC binding protein. EB1 protein family member 3. end-binding ... MAPRE3 microtubule associated protein RP/EB family member 3 [ Homo sapiens (human) ] Gene ID: 22924, updated on 7-Sep-2023 ...
Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration
The microtubule (MT) cytoskeleton of a mature axon is maintained in a stabilized steady state, yet after axonal injury it can ... The microtubule (MT) cytoskeleton of a mature axon is maintained in a stabilized steady state, yet after axonal injury it can ... Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration Dev Cell. 2012 Oct 16; ...
Impairment of microtubule-dependent trafficking by overexpression of alpha-synuclein
... Eur J Neurosci. 2006 Dec;24(11):3153-62. ... Here, we provide data suggesting a possible effect of aggregated alpha-syn on the microtubule (MT) network. Consistent with the ...
GJB6 gap junction protein beta 6 [Homo sapiens (human)] - Gene - NCBI
enables microtubule binding IDA Inferred from Direct Assay. more info. PubMed enables protein binding IPI Inferred from ...
Cfap20 cilia and flagella associated protein 20 [Mus musculus (house mouse)] - Gene - NCBI
located_in axonemal microtubule ISO Inferred from Sequence Orthology. more info. located_in cell projection IEA Inferred from ...
DNAH1 dynein axonemal heavy chain 1 [Homo sapiens (human)] - Gene - NCBI
MT; Microtubule-binding stalk of dynein motor. pfam12781. Location:3229 → 3444. AAA_9; ATP-binding dynein motor region D5. ... enables minus-end-directed microtubule motor activity IBA Inferred from Biological aspect of Ancestor. more info ...
Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow
... and random microtubule arrays. Proplatelets were predominant among BM sinusoids in the physiological state; however, during an ...
Springs, clutches and motors: driving forward kinetochore mechanism by modelling
As a mechanical system, the kinetochore can be viewed as a set of interacting springs, clutches and motors; the problem of kinetochore mechanism is now one of understanding how these functional modules assemble, disassemble and interact with one another to give rise to the emergent properties of the …
Actr1a ARP1 actin-related protein 1A, centractin alpha [Mus musculus (house mouse)] - Gene - NCBI
located_in microtubule cytoskeleton ISO Inferred from Sequence Orthology. more info. located_in myelin sheath HDA more info ...
CYP2A6 cytochrome P450 family 2 subfamily A member 6 [Homo sapiens (human)] - Gene - NCBI
located_in cytoplasmic microtubule IDA Inferred from Direct Assay. more info. PubMed ...
TUBE1 tubulin epsilon 1 [Homo sapiens (human)] - Gene - NCBI
Centriole triplet microtubules are required for stable centriole formation and inheritance in human cells. Wang JT, et al. ... involved_in microtubule cytoskeleton organization IBA Inferred from Biological aspect of Ancestor. more info ... EB1 recognizes the nucleotide state of tubulin in the microtubule lattice. Zanic M, et al. PLoS One, 2009 Oct 23. PMID 19851462 ... is_active_in microtubule IBA Inferred from Biological aspect of Ancestor. more info ...
KIFC1 kinesin family member C1 [Homo sapiens (human)] - Gene - NCBI
Predicted to enable microtubule binding activity and minus-end-directed microtubule motor activity. Involved in mitotic ... Microtub_bd; Microtubule binding. cl01090. Location:215 → 268. SlyX; SlyX. cl02488. Location:145 → 294. SPEC; Spectrin repeats ... Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters. Norris SR, et al. Nat Commun, 2018 Jul ... is_active_in microtubule organizing center IBA Inferred from Biological aspect of Ancestor. more info ...