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*  Characterization of the Discriminative Stimulus Effects of the Neuroactive Steroid Pregnanolone in DBA/2J and C57BL/6J Inbred...
Subjects. Twelve DBA/2J male mice, 13 DBA/2J female mice, 12 C57BL/6J male mice, and 12 C57BL/6J female mice were obtained from ... Pregnanolone. DBA/2J male mice (n = 12), DBA/2J female mice (n = 13), and C57BL/6J female mice (n = 12) acquired the ... for the male DBA/2J mice, 4 mg/kg (CI 3-5) for the female C57BL/6J mice, and 4 mg/kg (CI 1-7) for the female DBA/2J mice. There ... The ED50 values were 68 mg/kg (CI 58-77) for the male DBA/2J mice and 62 mg/kg (CI 39-84) for the female DBA/2J mice, which ...
http://jpet.aspetjournals.org/content/314/2/675
*  Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity | BMC Neuroscience | Full Text
Here we describe differences in the cortical area map of two commonly used inbred strains of laboratory mice, C57BL/6J and DBA/ ... Inbred strains of laboratory mice can be exploited to study cortical area map formation if there are significant phenotypic ... C57BL/6J and DBA/2J have markedly different cortical area maps, suggesting that inbred strains harbor enough phenotypic ... The sample of C57BL/6J and DBA/2J mice can be discriminated with 90% accuracy on the basis of these three size dimensions. ...
https://0-bmcneurosci-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2202-6-18
*  Interleukin 2 is not sufficient for the continuous growth of cloned NK-like cytotoxic cell lines.
Mice. Mice, Inbred BALB C. Mice, Inbred DBA. Rats. Rats, Inbred WF. T-Lymphocytes, Cytotoxic / cytology*. Time Factors. ... Whereas such lines would grow indefinitely in concanavalin A-induced mouse spleen cell supernatant, they would only grow for ...
http://www.biomedsearch.com/nih/Interleukin-2-not-sufficient-continuous/6605387.html
*  Immunohistochemical analysis of E2F in normal thyroid C | Open-i
Each positive-cell ratio calculated for the C-cells of Rb1D326V/+ (D326V) or Rb1+/− (+/−) mice was normalized with respect to ... Each positive-cell ratio calculated for the C-cells of Rb1D326V/+ (D326V) or Rb1+/− (+/−) mice was normalized with respect to ... mice (Fig.3a). These results indicate that, in the thyroid C-cells, "free" active E2F were unstable, while pRb-bound E2F were ... mice (Fig.3a). These results indicate that, in the thyroid C-cells, "free" active E2F were unstable, while pRb-bound E2F were ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4462357_cas0105-1360-f3&req=4
*  Tumor-infiltrating dendritic cell subsets of progressive or regressive tumors induce suppressive or protective immune responses...
Mice, Inbred DBA. *Neoplasms, Experimental (immunology, pathology) *T-Lymphocyte Subsets (immunology) *T-Lymphocytes, Cytotoxic ... Vaccination of mice with P815 tumor lysate-pulsed CD4+ 8+ TID815 or TID198 and CD4+ 8- TID198 induced IFN-gamma-secreting Th1 ... Transfer of CD4+ Tr1 cells obtained from CD4- 8- TID815-immunized wild-type, but not IL-10(-/-) mice, into CD4+ 8+ TID815 ... immunized mice abolished otherwise inevitable development of antitumor immunity. Taken together, our findings provide an ...
http://www.curehunter.com/public/pubmed15930318.do
*  IL-23 does not enhance CII-specific IL-17A production.( | Open-i
DBA/1 mice were immunized with CFA only, with CII/CFA or left untreated. At days 10 (CFA and CFA/CII) ... Mice. *Mice, Inbred C57BL. *Mice, Inbred DBA. *Neutralization Tests. *Polymerase Chain Reaction ... mice as well as to mice 25 days p.i and CIA-diseased mice (Figure 1A). However, injection of CFA only also induced a clear ... mice as well as to mice 25 days p.i and CIA-diseased mice (Figure 1A). However, injection of CFA only also induced a clear ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3585376_pone.0057553.g001&req=4
*  Effect of tacrolimus derivatives on immunosuppression.
Mice. Mice, Inbred BALB C. Mice, Inbred C3H. Mice, Inbred DBA. Polyethylene Glycols / pharmacology*. Prodrugs / pharmacology*. ...
http://www.biomedsearch.com/nih/Effect-tacrolimus-derivatives-immunosuppression/19407973.html
*  arthritis - BioMedLib™ search engine
Mice, Inbred DBA. Phytotherapy. Severity of Illness Index. *MedlinePlus Health Information. consumer health - Rheumatoid ... RESULTS: Prophylactic treatment of GIA mice with APL12 transgenic rice seeds (APL12-TG) significantly improved the severity of ... IL-17 production in splenocytes and iLN cells compared with non-transgenic rice-treated mice. ... in mice model of GPI induced arthritis (GIA). ... injury and serum urate were detected in hyperuricemic mice.. * ...
http://bmlreview.com/?&kwr=arthritis&smntc=plant&kwr=&ck=&cxts=10&fntszff=100&hghlght=maroon&srtrdr=relevance&annttn=none&pdthm=2010&hqryhstry=5062b3f288e4d101&pgwdth=100&mld=&wft=wims&b4s=180402295
*  Schematic diagrams illustrating in vivo rearrangements | Open-i
Mice, Inbred BALB C. *Mice, Inbred DBA. *Molecular Sequence Data. *Mutagenesis/physiology ... Mentions: Model of the Muta™Mouse λgt10-lacZ transgene derived by sequence analysis. The transgene monomer has 47 513 bp and 57 ... Mentions: Model of the Muta™Mouse λgt10-lacZ transgene derived by sequence analysis. The transgene monomer has 47 513 bp and 57 ... The multicopy λgt10-lacZ transgene shuttle vector of Muta™Mouse serves as an important tool for genotoxicity studies. Here, we ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2966988_mutagegeq048f02_ht&req=4
*  The activity strength of amygdala neurons is not differ | Open-i
The activity strength of amygdala neurons is not different in DBA/2 and FVB/N mice. Oregon -green BAPTA-AM was loaded into the ... Mice, Inbred DBA. *Models, Biological. *Naphthols/pharmacology. *Neurons/drug effects/physiology. *Propylene Glycols/ ... 581 for DBA/2 mice (n = 12 for mice and n = 27 for slices) and 1307 ± 676 for FVB/N mice (n = 11 for mice and n = 25 for slices ... 581 for DBA/2 mice (n = 12 for mice and n = 27 for slices) and 1307 ± 676 for FVB/N mice (n = 11 for mice and n = 25 for slices ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3475049_1756-6606-5-20-2&req=4
*  "Using gene expression databases for classical trait QTL candidate gene" by Lu Lu, Lai Wei et al.
RESULTS: QTL mapping of mouse forebrain weight in 34 BXD RI lines found significant association on chromosomes 1 and 11, with ... We recommend our approach when (1) investigators are working with phenotypic differences between C57BL/6J and DBA/2J, and (2) ... Quantitative RT-PCR confirmed the direction of an increased expression in C57BL/6J genotype over the DBA/2J genotype for both ... and that had forebrain mRNA abundance differing between C57BL/6J and DBA/2J, produced two candidates, Tnni1 (troponin 1) and ...
https://escholarship.umassmed.edu/oapubs/2275/
*  "Gamma-synuclein is a marker for retinal ganglion cell loss in glaucoma" by Dustin Pomerleau
Conclusion:In a genome wide screen of genes expressed in the mouse retina, we found aged DBA2/J retinas from 12 to 17 month old ... DBA2/J mice develop chronic, progressive glaucoma. In order to determine molecular pathways involved in the development of ... First strand cDNA was synthesized and hybridized to Affymetrix GeneChip Mouse Genome 430 2.0 gene expression microarrays. ... DBA2/J mice were homogenized and total RNA was extracted using Trizol and purified with Qiagen RNeasy separation columns. ...
https://escholarship.umassmed.edu/ssp/19/
*  A spontaneous mutation in Taar1 impacts methamphetamine-related traits exclusively in DBA/2 mice from a single vendor<...
DBA/2J recombinant inbred strains, and DBA/2 mice sourced from four vendors to further examine Taar1-MA phenotype relations and ... but not DBA/2 mice sourced from Charles River (DBA/2NCrl), Envigo (formerly Harlan Sprague Dawley; DBA/2NHsd) or Taconic (DBA/ ... but not DBA/2 mice sourced from Charles River (DBA/2NCrl), Envigo (formerly Harlan Sprague Dawley; DBA/2NHsd) or Taconic (DBA/ ... but not DBA/2 mice sourced from Charles River (DBA/2NCrl), Envigo (formerly Harlan Sprague Dawley; DBA/2NHsd) or Taconic (DBA/ ...
https://ohsu.pure.elsevier.com/en/publications/a-spontaneous-mutation-in-taar1-impacts-methamphetamine-related-t
*  Maternal TCDD exposure and effect of diet on gene expre | Open-i
... and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors. ... Results: Maternal TCDD exposure resulted in reduced litter size in D2 mice and, on HFD, reduced postpartum survival in B6 mice ... Results: Maternal TCDD exposure resulted in reduced litter size in D2 mice and, on HFD, reduced postpartum survival in B6 mice ... and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors. ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2737019_ehp-117-1414f5&req=4
*  Kcnj9 B6 vs. D2 PARC SNPs. Kcnj9 is represented with th | Open-i
Results: We sequenced the two most commonly used inbred mouse strains, DBA/2J and C57BL/6J, across a region of chromosome 1 ( ... Results: We sequenced the two most commonly used inbred mouse strains, DBA/2J and C57BL/6J, across a region of chromosome 1 ( ... Conclusion: Comparisons utilizing even two of the best characterized mouse genetic models, DBA/2J and C57BL/6J, indicate that ... Conclusion: Comparisons utilizing even two of the best characterized mouse genetic models, DBA/2J and C57BL/6J, indicate that ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2743714_1471-2164-10-379-5&req=4
*  Edward Stuart Brodkin | Members | Institute for Translational Medicine and Therapeutics | Perelman School of Medicine at the...
Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice. Brain Research 1002: 151-157, 2004.. Brodkin E.S ... BALB/cJ inbred mouse strains. Biological Psychiatry 59: 415-423, 2006.. Gillihan S.J., Farah M.J., Sankoorikal G.M.V., Breland ... Low sociability is associated with reduced size of the corpus callosum in the BALB/cJ inbred mouse strain. Brain Research 1230 ... Sankoorikal G.M.V., Kaercher K.A., Boon C.J., Lee J.K., Brodkin E.S. : A mouse model system for genetic analysis of sociability ...
http://www.med.upenn.edu/apps/faculty/index.php/g5455356/p33126
*  "Ligation of TLR5 promotes myeloid cell infiltration and differentiatio" by Seung-Jae Kim, Zhenlong Chen et al.
Last, to evaluate the importance of TLR5 function in RA, we used anti-TLR5 Ab therapy in CIA mice. We show that TLR5 agonist, ... Studies were conducted to investigate the role of TLR5 ligation on RA and mouse myeloid cell chemotaxis or osteoclast formation ... and osteoclast maturation directly through myeloid TLR5 ligation and indirectly via TNF-alpha production from RA and mouse ... Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Middle Aged; Monocytes; Myeloid Progenitor Cells; NF-kappa B; Osteoclasts; ...
https://escholarship.umassmed.edu/rheumatology_pubs/49/
*  "A novel paramagnetic substrate for detecting myeloperoxidase activity " by Mohammed S. Shazeeb, Suresh Gupta et al.
In vivo magnetic resonance imaging (MRI) in mice demonstrated that bis-HTrp-DTPA(Gd) was retained for up to 5 days in MPO- ... Mice; Mice, Inbred DBA; Muscle, Skeletal; Oxidation-Reduction; Pentetic Acid; Peroxidase; Solubility ... In vivo magnetic resonance imaging (MRI) in mice demonstrated that bis-HTrp-DTPA(Gd) was retained for up to 5 days in MPO- ...
https://escholarship.umassmed.edu/radiology_pubs/89/
*  Frontiers | Impaired Social Behavior in 5-HT3A Receptor Knockout Mice | Frontiers in Behavioral Neuroscience
Other mouse models in which serotonergic signaling was disrupted during development showed similar morphological changes in the ... Other mouse models in which serotonergic signaling was disrupted during development showed similar morphological changes in the ... So far, analysis of the 5-HT3A knockout mouse revealed changes in nociceptive processing and a reduction in anxiety related ... Here, we subjected male and female 5-HT3A knockout mice and their non-transgenic littermates to several tests of social ...
https://www.frontiersin.org/articles/10.3389/fnbeh.2010.00169/full
*  Frontiers | Neurosteroid Influences on Sensitivity to Ethanol | Endocrinology
Shelton, K. L., and Grant, K. A. (2002). Discriminative stimulus effects of ethanol in C57BL/6J and DBA/2J inbred mice. Alcohol ... Discriminative stimulus effects of 5.6 mg/kg pregnanolone in DBA/2J and C57BL/6J inbred mice. Alcohol 37, 35-45. ... of the discriminative stimulus effects of the neuroactive steroid pregnanolone in DBA/2J and C57BL/6J inbred mice. J. Pharmacol ... or male mice (49 pg/ml), but 3α,5α-THP, 3α,5β-THP, and 3α,5α-THDOC were much lower in cynomolgus monkeys compared to rats, mice ...
https://www.frontiersin.org/articles/10.3389/fendo.2012.00010/full
*  Find Research Outputs - University of Aberdeen
Between and within laboratory reliability of mouse behaviour recorded in home-cage and open-field. Robinson, L., Spruijt, B. & ... Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice. Meakin, P. J., Jalicy, S. M., ... Inbred DBA Mouse Photoperiod Between Conflict and Peace: An Analysis of the Complex Consequences of the Good Friday Agreement. ...
https://abdn.pure.elsevier.com/en/publications/?format=&page=6
*  Examples for variations of expression levels in differe | Open-i
Examples for variations of expression levels in different BXD and inbred mouse strains and ge-nome-wide analysis of cis- and ... Mice, Inbred BALB C. *Mice, Inbred C57BL. *Mice, Inbred DBA. *Oligonucleotide Array Sequence Analysis ... Figure 7: Examples for variations of expression levels in different BXD and inbred mouse strains and ge-nome-wide analysis of ... Figure 7: Examples for variations of expression levels in different BXD and inbred mouse strains and ge-nome-wide analysis of ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC3105947_1465-9921-12-61-7&req=4
*  Bone destruction is prevented by interleukin (IL)-4 and | Open-i
Methods: DBA-1J/Bom mice were immunized with bovine type II collagen and boosted at day 21. Mice with established CIA were ... Methods: DBA-1J/Bom mice were immunized with bovine type II collagen and boosted at day 21. Mice with established CIA were ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC17779_ar-1-1-081-8&req=4
*  Paclitaxel released from a self-assembling supramolecul | Open-i
Mice, Inbred DBA. *Molecular Dynamics Simulation. *Structure-Activity Relationship. Related in: MedlinePlus ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4206202_dddt-8-1839Fig2&req=4
*  Computational simulation of SAMTA7 (A) and the SAMTA7-p | Open-i
Mice, Inbred DBA. *Molecular Dynamics Simulation. *Structure-Activity Relationship. Related in: MedlinePlus ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4206202_dddt-8-1839Fig5&req=4