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*  NIOSHTIC-2 Publications Search - 20041702 - Susceptibility to noise-induced hearing loss in two congenic mouse strains.
Recently, Johnson has developed two relevant congenic mouse strains. In the congenic C57B ... identified a single genetic locus (Ahl) that could explain the early presbycusis observed in the inbred C57BL/6J mouse strain. ... Recently, Johnson has developed two relevant congenic mouse strains. In the congenic C57BL/6J strain, the Ahl locus has been ... This would be expected based on the fact that the congenic CBA.B6 mice genotypes included the mutant Ahl locus. This ...
https://www.cdc.gov/niosh/nioshtic-2/20041702.html
*  A congenic mouse and candidate gene at the Chromosome 13 locus regulating bone density, Mammalian Genome | 10.1007/s00335-001...
"A congenic mouse and candidate gene at the Chromosome 13 locus regulating bone density, Mammalian Genome" on DeepDyve, the ... A congenic mouse and candidate gene at the Chromosome 13 locus regulating bone density. A congenic mouse and candidate gene at ... A congenic mouse and candidate gene at the Chromosome 13 locus regulating bone density. Shimizu, Motoyuki; Higuchi, Keiichi; ... lp/springer_journal/a-congenic-mouse-and-candidate-gene-at-the-chromosome-13-locus-Kr59c8uN3Q ...
https://www.deepdyve.com/lp/springer_journal/a-congenic-mouse-and-candidate-gene-at-the-chromosome-13-locus-Kr59c8uN3Q
*  Corneal Hazing Phenotype in ALDH3A1 Congenic Knockout Mice | IOVS | ARVO Journals
Corneal Hazing Phenotype in ALDH3A1 Congenic Knockout Mice Vasilis Vasiliou; Vindhya Koppaka; Satori Marchitti; Ying Chen; ... Corneal Hazing Phenotype in ALDH3A1 Congenic Knockout Mice You will receive an email whenever this article is corrected, ... Methods: Transparency in the corneal stroma was examined in our recently-developed Aldh3a1(-/-) congenic transgenic mice bred ... Corneal Hazing Phenotype in ALDH3A1 Congenic Knockout Mice. Invest. Ophthalmol. Vis. Sci. 2014;55(13):5155. ...
https://iovs.arvojournals.org/article.aspx?articleid=2270736
*  Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and...
... were significantly different in A/J-12SM mice from those in A/J mice. In this study, using congenic mice analysis, we narrowed ... The aim of this study was to narrow the Fl1sa region by genetic dissection using novel congenic mice and to identify candidate ... Liver triglyceride content in R2 and R3 mice was significantly lower than that in A/J mice fed with a high-fat diet for 7 weeks ... were significantly different in A/J-12SM mice from those in A/J mice. In the liver, mRNA levels of Iah1 (in R2) and Rrm2 (in R2 ...
https://bmcgenet.biomedcentral.com/articles/10.1186/s12863-016-0453-7
*  Pupillary responses in the C57BL/6J and congenic IRBP knockout mouse | IOVS | ARVO Journals
Pupillary responses in the C57BL/6J and congenic IRBP knockout mouse Kevin Joseph Donaldson; Shanu Markand; Jana T Sellers; ... Pupillary responses in the C57BL/6J and congenic IRBP knockout mouse You will receive an email whenever this article is ... Pupillary responses in the C57BL/6J and congenic IRBP knockout mouse. Invest. Ophthalmol. Vis. Sci. 2016;57(12):641. ... Methods : Pupil diameters of 90 day old, male IRBP knockout (KO) and C57BL/6J (WT) mice, were measured using a custom ...
https://iovs.arvojournals.org/article.aspx?articleid=2559444
*  Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?
Abstract Background Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice ... Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?. ... congenic mice, we conducted the proper F2 controls and discovered significant differences between these F2 animals and MHC- ... Conclusions These data suggest that these strains differ for genes other than those in the MHC congenic region. The most likely ...
http://journaldatabase.info/articles/infection-dependent_phenotypes.html
*  Comparative gene expression profiling in two congenic mouse strains following Bordetella pertussis infection | BMC Microbiology...
HcB-28 mice are more resistant to B. pertussis infection than C3H mice, which could partially be ascribed to the B. pertussis ... Twelve and a half percent of the genomes of these mice are from a different genetic background. Upon B. pertussis inoculation ... Two hundred and six genes were differentially expressed between the two mouse strains, but, remarkably, none of these were up- ... Eight of these genes, which showed a strong difference in gene expression between the two mouse strains, map to the ...
https://0-bmcmicrobiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2180-7-88
*  "A BALB/c Congenic Strain of Mice That Carries a Genetic Locus ...
... congenic mice were developed by introgressively backcrossing the Idh-1b and Pep-3b markers of DBA/2 mice onto the BALB/cπ mice ... BALB/c.DBA/2 Idh-1b-Ityr-Pep-3b mice were resistant to in vivo infections by Salmonella typhimurium, Mycobacterium bovis, and ... congenic mice were developed by introgressively backcrossing the Idh-1b and Pep-3b markers of DBA/2 mice onto the BALB/cπ mice ... A BALB/c Congenic Strain of Mice That Carries a Genetic Locus (Ityr) Controlling Resistance to Intracellular Parasites ...
https://digitalcommons.unl.edu/usuhs/98/
*  Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals? | BMC Immunology | Full...
... congenic mice, we conducted the proper F2 controls and discovered significant differences between these F2 animals and MHC- ... MHC-congenic strain has been separated from its B10-H-2 b parental strain. During typical experiments with congenic strains, ... These mice have great importance in evaluating the function of genes. However, their utility depends on the maintenance of this ... These data suggest that these strains differ for genes other than those in the MHC congenic region. The most likely explanation ...
https://bmcimmunol.biomedcentral.com/articles/10.1186/1471-2172-5-14
*  Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic...
Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic ... At the same time, 5-hydroxyindoleacetic acid (5-HIAA) was significantly elevated in BALB/c congenic mice. In C57Bl/6 mice, ... To test the role of the C1473G polymorphism in strain differences, we generated C57Bl/6 and BALB/c mice congenic for the Tph2 ... BALB/c mice had lower expression of monoamine oxidase A and B than C57Bl/6 mice, but there was no effect of Tph2 genotype. On ...
https://scholars.duke.edu/display/pub763978
*  Altered monoaminergic systems and depressive-like behavior in congenic prion protein nnock-out mice - Zurich Open Repository...
Nuvolone M et al; Altered Monoaminergic Systems and Depressive-like Behavior in Congenic Prion Protein Knock-out Mice. J ... Altered monoaminergic systems and depressive-like behavior in congenic prion protein nnock-out mice ... Altered monoaminergic systems and depressive-like behavior in congenic prion protein nnock-out mice. Journal of Biological ...
http://www.zora.uzh.ch/id/eprint/114215/
*  Identification of new loci controlling collagen-induced arthritis in mouse using a partial advanced intercross and congenic...
Identification of new loci controlling collagen-induced arthritis in mouse using a partial advanced intercross and congenic ... Identification of new loci controlling collagen-induced arthritis in mouse using a partial advanced intercross and congenic ... using a partial advanced intercross and a collection of congenic strains. The chromosome 14 congenic fragment, containing the T ... using a partial advanced intercross and a collection of congenic strains. The chromosome 14 congenic fragment, containing the T ...
https://lup.lub.lu.se/search/publication/1247152
*  Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11 |...
Rogner UC, Avner P (2003) Congenic mice: cutting tools for complex immune disorders. Nat Rev Immunol 3:243-252CrossRefPubMed ... Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11. ... We named this locus Stzds1 (STZ-induced diabetes susceptibility 1). Congenic mapping using the Chr. 11 congenic strains ... 11) congenic strains developed from A/J-11SM to identify a candidate STZ-induced diabetes susceptibility gene. The A/J strain ...
https://link.springer.com/article/10.1007/s00335-018-9742-y
*  Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression...
Congenic mice were used at the second generation after being made homozygous. Congenic mice were co-housed under the same ... congenic excluding the congenic region. The percentage of genes that are differentially expressed in the congenic mice and on ... Congenic mice. All mouse work was conducted at the International Livestock Research Institute in Nairobi and approved by their ... In the spleen of the congenic mice 55 of 77 (71%) differentially expressed genes were outside the congenic interval and ...
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-11-361
*  Low ambient humidity impairs barrier function and innate resistance against influenza infection | PNAS
Mice.. C57BL/6 mice carrying a functional Mx1 allele (37) were used. Caspase-1/11 KO mice crossed to Mx1 congenic mice have ... Low relative humidity predisposes Mx1 congenic mice to influenza disease. Mx1 congenic mice were preconditioned at 20% and 50% ... Mx1 congenic WT mice or caspase-1/11 KO Mx1 mice were preconditioned at 10% and 50% RH for 5 d and challenged with aerosolized ... Low Ambient Humidity Leads to More Severe Disease in Mx1 Congenic Mice.. Mx1 mice at 50% RH were infected with varying doses of ...
https://www.pnas.org/content/early/2019/05/07/1902840116
*  Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci, Mammalian...
"Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci, Mammalian ... Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci. Congenic ... Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci. Prevoršek ... Mapping by genetic interaction-high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse ...
https://www.deepdyve.com/lp/springer_journal/congenic-and-bioinformatics-analyses-resolved-a-major-effect-fob3b-qtl-4HrKsJQl7c
*  Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression...
Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression ... Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression ...
https://cgspace.cgiar.org/handle/10568/2324
*  Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse. - Radcliffe Department of Medicine
We have successively localized the hph-1 mutation to a congenic interval of 1.6-2.8 Mb, containing the GCH gene encoding GTP ... These new findings will extend the utility of the hph-1 mouse in studies of GTP-CH I deficiency. ... hph-1 and heterozygote mice, and found that heterozygote animals have partial tetrahydrobiopterin deficiency. ... The hph-1 ENU-mutant mouse provides a model of tetrahydrobiopterin deficiency for studying hyperphenylalaninaemia, dopa- ...
https://www.rdm.ox.ac.uk/publications/32772
*  Diabetes Protection and Restoration of Thymocyte Apoptosis in NOD Idd6 Congenic Strains | Diabetes
Idd6 congenic mice and 28 wild-type N.N.Idd6 littermates (A). The incidence in males was measured in 54 N.Idd6 congenic mice ... Cumulative incidence of type 1 diabetes in Idd6 congenic mice. During a 45-week period, N.Idd6 and N.N.Idd6 congenic male and ... The level of apoptosis induction in N.Idd6-15 mice is similar to the high level observed in B6 mice, whereas B.Idd6 mice ... Restoration of thymocyte apoptosis induction in Idd6 congenic mice.. NOD, B6, N.Idd6-15, and B.Idd6 females were analyzed 12 h ...
http://diabetes.diabetesjournals.org/content/52/7/1677
*  Plus it
N12 backcross generation NOD mice congenic for a disrupted CD1d gene (NOD.CD1dnull) have been described (13). NOD mice ... B6 mice congenic for the NOD-derived H2g7 MHC (B6.H2g7) are maintained at the N8 backcross generation (12). ... A: DCs were purified from NOD and B6.H2g7 mice treated with α-GalCer and either anti-PD-L1 (400 μg/mouse) or rIgG 24 h and 16 h ... Conversely, B6.H2g7 mice have unimpaired iNKT-cells and DCs. This may account for why in α-GalCer-treated B6.H2g7 mice, DCs ...
http://diabetes.diabetesjournals.org/content/59/2/423
*  prof. dr. Roosmarijn Vandenbroucke
Passenger mutations confound interpretation of all genetically modified congenic mice Tom Vanden Berghe (UGent) , Paco Hulpiau ... With mouse age comes wisdom : a review and suggestions of relevant mouse models for age-related conditions Susanne Drechsler, ... Mouse models of ageing and their relevance to disease Sulev Kõks, Soner Dogan, Bilge Guvenc Tuna, Herminia González-Navarro, ... Efficient analysis of mouse genome sequences reveal many nonsense variants Sophie Steeland (UGent) , Steven Timmermans (UGent) ...
https://biblio.ugent.be/person/001999642367?sort=year.desc&sort=datecreated.desc&limit=50&start=
*  Distinct Regulation of Murine Lupus Susceptibility Genes by the IRF5/Blimp-1 Axis | The Journal of Immunology
F1 spontaneous mouse model of SLE (28-32). Accordingly, B6 mice congenic for the Nba2 interval (congenic mice indicated as B6. ... B6.Sle123 congenic (congenic for the NZM2410 lupus-prone strain-derived Sle1, Sle2, and Sle3 loci) mice spontaneously develop ... 7) congenic female mice, as compared with age-matched B6 female mice, is associated with increased expression of p202 protein. ... lpr mice (7). Because development of lupus-like disease in B6.Nba2 congenic female mice depends on type I IFN signaling (35), ...
http://www.jimmunol.org/content/188/1/270.full
*  Rat and Mice Breeding Services | Charles River
Charles River has experience breeding mice and rats with all types of genetic mutations, including knockout, transgenic, ... All fully congenic mice produced. 15 months. Colony Startup Package. Get an established colony quickly ... Breeding of Mice & Rats. Charles River provides a full-service rodent colony management program to deliver animals to you when ... Rapid: Direct animal and environmental samples tested via Mouse Surveillance Plus PRIA™ ...
https://www.criver.com/products-services/research-models-services/genetically-engineered-model-services/mouse-rat-breeding
*  JCI - Lysosomal β-glucuronidase regulates Lyme and rheumatoid arthritis severity
Severely arthritic C3H mice possessed a naturally occurring hypomorphic allele, Gusbh. . C57BL/6 mice congenic for the C3H Gusb ... C3H mice expressing WT Gusb. as a transgene were protected from severe Lyme arthritis. Importantly, the Gusbh. allele also ... expressing mice was associated with heightened accumulation of GAGs in joint tissue. We propose that GUSB modulates arthritis ...
https://www.jci.org/articles/view/72339/pdf