Center for Theoretical & Mathematical Sciences » People
Metabolic Detoxication, Drug • Metabolic Networks and Pathways • Metabolome • Metamorphosis • Metamorphosis, Biological • ... Currently metabolic networks (e.g. folate metabolism) are being used to develop a deeper understanding of the functional ... Currently metabolic networks (e.g. folate metabolism) are being used to develop a deeper understanding of the functional ... Callier, V; Nijhout, HF, Supply-side constraints are insufficient to explain the ontogenetic scaling of metabolic rate in the ...http://fds.duke.edu/db/aas/math/ctms/faculty/hfn
The respiration rate of the beet armyworm pupae (Spodoptera exigua) after multi-generation intoxication with cadmium and zinc.
Metabolic Detoxication, Drug. Pupa / drug effects, physiology. Respiration / drug effects*. Respiratory Physiological Phenomena ...http://www.biomedsearch.com/nih/respiration-rate-beet-armyworm-pupae/12860096.html
SOD3 wt Allele - Semantic Scholar
Metabolic Detoxication, Drug. Oxidation-Reduction. Oxidative Stress. Related mentions per year. Related mentions per year. 1936 ...https://www.semanticscholar.org/topic/SOD3-wt-Allele/10829250
List of MeSH codes (G12) - Wikipedia
... metabolic detoxication, drug MeSH G12.091.690.140.600.500 --- metabolic detoxication, phase i MeSH G12.091.690.140.600.750 --- ... drug antagonism MeSH G12.361.477 --- drug synergism MeSH G12.361.511 --- food-drug interactions MeSH G12.361.755 --- herb-drug ... drug resistance, fungal MeSH G12.392.269.383.500 --- drug resistance, multiple, fungal MeSH G12.392.269.420 --- drug resistance ... drug resistance, multiple, bacterial MeSH G12.392.300.625 --- drug resistance, multiple, fungal MeSH G12.392.300.750 --- drug ...https://en.wikipedia.org/wiki/List_of_MeSH_codes_(G12)
List of MeSH codes (G06) - Wikipedia
... metabolic detoxication, drug MeSH G06.535.780.202.820.500 --- metabolic detoxication, phase i MeSH G06.535.780.202.820.750 --- ... metabolic detoxication, phase ii MeSH G06.535.780.559 --- therapeutic equivalency MeSH G06.535.780.917 --- tissue distribution ...https://en.wikipedia.org/wiki/List_of_MeSH_codes_(G06)
Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic Syndrome - Full Text View -...
Metabolic Syndrome Drug: Xenical, Pionorm, Diroton, Diltiazem, Atorvastatin Dietary Supplement: 'Analimentary detoxication' ... MedlinePlus related topics: Metabolic Syndrome Drug Information available for: Diltiazem Orlistat Atorvastatin Diltiazem malate ... Experimental: 'Analimentary detoxication' Weight loss Vegetables and salt diet. Dietary Supplement: 'Analimentary detoxication ... Metabolic Syndrome. Disease. Pathologic Processes. Insulin Resistance. Hyperinsulinism. Glucose Metabolism Disorders. Metabolic ...https://www.clinicaltrials.gov/ct2/show/NCT02503865?cntry=KZ&
3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic...
Vincent-Viry M, Fournier B, and Galteau MM (2000) The effects of drinking and smoking on the CYP2D6 metabolic capacity. Drug ... Williams RT (1959) Detoxication Mechanisms. John Wiley & Sons Inc., New York.. *↵ Wilson ID, Nicholson JK, Castro-Perez J, ... In turn, this may have implications for studies in which the metabolic ratio is correlated with the metabolism of a second drug ... both metabolic and nonmetabolic, that surely dictate the pattern of urinary metabolites of a drug such as debrisoquine. The ...http://dmd.aspetjournals.org/content/34/9/1563
Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information
Implications for the catechol-O-methyl transferase-mediated detoxication of catechol estrogens. Drug Metab Dispos 24: 588-594. ... Metabolic pathway model and functional annotations. Metabolic reactions were imported from three independent human metabolic ... The comprehensive metabolic picture provided by GGMs in combination with GWAS allows for the detailed analysis of metabolic ... Acharya KR, Sturrock ED, Riordan JF, W MR (2003) Ace revisited: a new target for structure-based drug design. Nat Rev Drug ...http://pubmedcentralcanada.ca/pmcc/articles/PMC3475673/
Mechanisms for the Generation of Oxygen Radicals by Drugs | SpringerLink
The term drug is used here in its widest sense and includes any... ... In this report I will give a brief overview of drug-dependent metabolic reactions that can generate reactive oxygen species in ... D.S. Hewick, Reductive metabolism of nitrogen-containing functional groups, In: "Metabolic Basis of Detoxication," W.B. Jakoby ... In this report I will give a brief overview of drug-dependent metabolic reactions that can generate reactive oxygen species in ...https://link.springer.com/chapter/10.1007/978-1-4684-5568-7_117
Differential responses of antioxidant system and photosynthetic characteristics in four rice cultivars differing in sensitivity...
Metabolic Detoxication, Drug. *chlorophyll fluorescence. *Biomass. *Antioxidants. *Avian crop. *viral capsid secondary ... Susceptibility and tolerance of rice crop to salt threat: Physiological and metabolic inspections. *Nyuk Ling Ma, Wan Afifudeen ...https://www.semanticscholar.org/paper/Differential-responses-of-antioxidant-system-and-in-Sarkar-Mahata/7862091fe8e685e1f8c7db37ac89ad0f96c34662
Profiles in drug metabolism and toxicology: Richard Tecwyn Williams (1909-1979)
... the biliary excretion of drugs was extensively studied as were species differences in drug metabolism and detoxication. Besides ... In particular, the concepts of phase 1 and phase II metabolic pathways were introduced by Williams; ... Drug metabolism; detoxication; history; toxicology; xenobiotics National Category Health Sciences Identifiers. URN: urn:nbn:se: ... Faculty of Medicine and Health SciencesDivision of Drug Research In the same journal. Drug metabolism reviews (Softcover ed.) ...http://liu.diva-portal.org/smash/record.jsf?pid=diva2:896768
The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 1, 1909-1958 | Drug Metabolism &...
Brodie BB, Axelrod J, Cooper JR, Gaudette L, La Du B, Mitoma C, and Udenfriend S (1955) Detoxication of drugs and other foreign ... Inhibitory effects of β-diethylaminoethyldiphenylpropylacetate on a variety of drug metabolic pathways in vitro. J Pharmacol ... Bachmann C and Bickel MH (1985) History of drug metabolism: the first half of the 20th Century. Drug Metab Rev 16: 185-253. ... Conti A and Bickel MH (1977) History of drug metabolism. Discoveries of the major pathways in the 19th century. Drug Metab Rev ...http://dmd.aspetjournals.org/content/36/1/1
Detoxication | definition of detoxication by Medical dictionary
... detoxication explanation free. What is detoxication? Meaning of detoxication medical term. What does detoxication mean? ... Looking for online definition of detoxication in the Medical Dictionary? ... metabolic detoxification reduction of the toxic properties of a substance by chemical changes induced in the body, producing a ... 2. treatment designed to assist in recovery from the toxic effects of a drug. ...http://medical-dictionary.thefreedictionary.com/detoxication
US Patent # 7,767,679. Sulfonylamino-derivatives as novel inhibitors of histone deacetylase - Patents.com
The major organ for drug metabolism is the liver. The metabolic products are often less active than the parent drug or inactive ... Thus drug metabolism may include both "detoxication" and "toxication" processes. One of the major enzyme systems that determine ... For each experiment, controls (containing no drug) and a blank incubation (containing no cells or drugs) were run in parallel. ... For each experiment, controls (containing no drug) and a blank incubation (containing no cells or drugs) were run in parallel. ...http://patents.com/us-7767679.html
Metabolic demand | definition of metabolic demand by Medical dictionary
... metabolic demand explanation free. What is metabolic demand? Meaning of metabolic demand medical term. What does metabolic ... Looking for online definition of metabolic demand in the Medical Dictionary? ... Metabolic derangement. *Metabolic detoxication, drug. *Metabolic detoxication, drug. *Metabolic detoxication, drug. *metabolic ... metabolic demand. Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia. metabolic demand. Abbreviation: Q/VO2. ...https://medical-dictionary.thefreedictionary.com/metabolic+demand
Graduate - Department of Veterinary Physiology & Pharmacology
Metabolic and Detoxication Mechanisms. (3-0). Credit 3. Fate of foreign compounds; their inhibitory and antagonistic action ... physiochemical or physiologic effects of drugs at sites from molecular to whole body. Prerequisite: Approval of instructor. ... toward normal metabolic processes of the animal body. Prerequisites: BICH 603; approval of instructor and department head. ...https://vetmed.tamu.edu/vtpp/courses/graduate/
Coordinated induction of drug transporters and phase I and II metabolism in human liver slices. - PubMed - NCBI
Metabolic Detoxication, Phase I. *Metabolic Detoxication, Phase II. *Pharmaceutical Preparations/metabolism*. Substances. * ... The concomitant induction of metabolic enzymes and transporters shows that also in the human liver transporters and metabolic ... CAR and AhR-mediated induction of drug transporters and phase I and II metabolic enzymes. Precision-cut human liver slices were ... Coordinated induction of drug transporters and phase I and II metabolism in human liver slices.. Olinga P1, Elferink MG, ...https://www.ncbi.nlm.nih.gov/pubmed/18328680?dopt=Abstract
940. Safety evaluations of groups of related substances... (WHO Food Additives Series 42)
Williams, R.T. (1959) Detoxication Mechanisms: The Metabolism and Detoxication of Drugs, Toxic Substances and Other Organic ... Drug Metab. Disposition, 16, 721-727. Duterte-Catella, H., Nguyen, P., Dang, Q. & Truhaut, R. (1978) Metabolic transformations ... Williams, R.T. (1939) Studies in detoxication. III. The use of the glucuronic acid detoxication mechanism of the rabbit for the ... and the metabolic fate of trans-methyl styryl ketone in the male Fischer 344 rat. Drug Metab. Disposition, 25, 732-739. Savary ...http://inchem.org/documents/jecfa/jecmono/v042je14.htm
Welcome to LibAge, the ageing reference resource
Metabolic Detoxication, Drug/genetics *Polymerase Chain Reaction *Polymorphism, Genetic/genetics *Reference Values ...http://libage.ageing-map.org/entries/tags/90/
A phase 1 study of eribulin mesylate (E7389), a novel microtubule-targeting chemotherapeutic agent, in children with refractory...
Metabolic Detoxication, Phase I. Functionalization of exogenous substances to prepare them for conjugation in PHASE II ... Induction or antagonism of phase I detoxication is the basis of a number of DRUG INTERACTIONS. ... RATIONALE: Drugs used in chemotherapy, such as E7389, work in different ways to stop the growth of tumor cells, either by ... All Topics Biotechnology Biotech Business Biotech Products Cancer Cardiovascular Dermatology Drug Discovery Endocrinology ...https://www.bioportfolio.com/resources/pmarticle/2035531/A-phase-1-study-of-eribulin-mesylate-E7389-a-novel-microtubule-targeting.html
Booser D. J., Hortobagyi G. N. Anthracycline antibiotics in cancer therapy: focus on drug resistance. Drugs, 47: 223-258, 1994. ... Bartoszek A. Metabolic activation of Adriamycin by NADPH-cytochrome P450 reductase: overview of its biological and biochemical ... it is important to keep in mind that CYPRED also plays an important role in the detoxication of this anthracycline via the ... 4A) ⇓ . As a positive control, we also tested the MDA231 cell lines for their sensitivity to tirapazamine, a drug that is known ...http://cancerres.aacrjournals.org/content/63/20/6914
Indian Patents. 250047:'AN INDOLYL-, BENZOTHENYL-, OR BENZOFURANYL-ALKYL AMINO COMPOUND OF FORMULA (I)'
The major organ for drug metabolism is the liver. The metabolic products are often less active than the parent drug or inactive ... Thus drug metabolism may include both "detoxication" and "toxication" processes. One of the major enzyme systems that determine ... compound with low metabolic stability (% metabolism = 73 %). Cisapride was included as a compound with medium metabolic ... For each experiment, controls (containing no drug) and a blank incubation (containing no cells or drugs) were run in parallel. ...http://www.allindianpatents.com/patents/250047-an-indolyl-benzothenyl-or-benzofuranyl-alkyl-amino-compound-of-formula-i
MOLECULAR INTERACTIONS BETWEEN MYCOTOXINS AND LIVER ENZYMES INVOLVED IN DRUG METABOLISM IN RODENTS AND FARM ANIMALS - pdf...
MOLECULAR INTERACTIONS BETWEEN MYCOTOXINS AND LIVER ENZYMES INVOLVED IN DRUG METABOLISM IN RODENTS AND FARM ANIMALS. . ... Interactions between mycotoxins and liver drug metabolizing are crucial in terms of detoxication or bioactivation of these ... Most of these interactions are consequences of the metabolic processes occurring in the liver. They result generally from the ... mycotoxins; liver enzimes; drug metabolism; rodents; farm animals. Autor: Pierre Galtier - ; Laboratoire de Pharmacologie- ...http://libros.duhnnae.com/2017/jun7/149805934621-MOLECULAR-INTERACTIONS-BETWEEN-MYCOTOXINS-AND-LIVER-ENZYMES-INVOLVED-IN-DRUG-METABOLISM-IN-RODENTS-AND-FARM-ANIMALS.php
Genetic Defects in Synthesis and Transport of Bile Acids | Pediatric Endocrinology and Inborn Errors of Metabolism, 2e |...
In contrast to detoxication reactions, however, some of the reactions are highly specific and subject to metabolic control. The ... and enzyme systems involved in this conversion are similar to those involved in detoxication and elimination of various drugs: ... end result of the conversion of both cholesterol and various lipophilic drugs is biliary or renal elimination of a water- ...http://accesspediatrics.mhmedical.com/content.aspx?bookid=2042§ionid=154112839