... coordinated expression of functionally related genes during proliferation and differentiation of rainbow trout adipocyte cells ... mesenchymal stem cells), day 8 (proliferated cells), day 15 (committed preadipocytes) and day 21 (mature adipocytes). The cells ... triiodothyronine and fat soluble vitamins on adipocyte differentiation and LPL gene expression in the stromal-vascular cells of ... Selected genes involved in cell commitment and remodelling. a Cell commitment; b Adipogenic markers; c Cell remodelling; d ...

With a variety of assays we could show that MSC represent a cell population which can be expanded for therapeutic applications. ... Human mesenchymal stem cells (MSC) with the capacity to differentiate into osteoblasts provide potential for the development of ... way during ex vivo long-term cultivation and if artificial cultivation conditions exert any influence on their stem cell ... Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells ...

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts? Cell Death Differ. 2016;23(7):1128-39. ... Transcriptome comparison between porcine subcutaneous and intramuscular stromal vascular cells during adipogenic ... Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells. Mol Cell ... The role of cellular proliferation in adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells. Stem ...

... and necessitates specific alterations in cell metabolism. Although several EMT-related metabolic changes have been described in ... At molecular level, these processes may be triggered by epithelial-mesenchymal transition (EMT) ... ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in ... EMT is the conversion of epithelial cells into cells with a mesenchymal phenotype, which is accompanied by a decrease in cell- ...

SLC1A3 exhibited cytoplasmic staining in tumor and stromal cells; whereas IL8 staining was found in both osteoclasts and ... mesenchymal-epithelial transition factor. erbB-2 :. v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/ ... Cell lines. Expression analysis of human (U2, HOS and MG63) and canine (MC-KOSA and BW-KOSA) osteosarcoma cell lines included ... Single species cluster dendrograms define canine and human osteosarcoma as distinct from normal organs and osteosarcoma cell ...

Early postpartum, enriched immune pathways (adjusted P < 0.1) included the T cell receptor signalling pathway, graft-versus- ... and in endometrial epithelial and stromal cells in response to LPS in vitro[12]. ... epithelial-to-mesenchymal transition, angiogenesis, apoptosis resistance and proliferation. Src members are activated by the ... These pathways included T cell receptor signalling, cytokine-cytokine receptor interaction, natural killer cell mediated ...

Hausman GJ, Dodson MV: Stromal vascular cells and adipogenesis: cells within adipose depots regulate adipogenesis. J Genomics. ... the extracellular environment regulates the proliferation and differentiation of mesenchymal stem cells and satellite cells [41 ... Main signaling pathways are involved in assembly of actin cytoskeleton, cell adhesion to the extracellular matrix, cell-cell ... and adipose tissue-derived stromal cells: a key role of Kruppel-like factor 4 in cell fate regulation. Cytotherapy. 2011, 13 (3 ...