Myocyte Enhancer Factor 2C as a Neurogenic and Antiapoptotic Transcription Factor in Murine Embryonic Stem Cells | Journal of...  Myocyte Enhancer Factor 2C as a Neurogenic and Antiapoptotic Transcription Factor in Murine Embryonic Stem Cells | Journal of...
MCM1-agamous-deficiens-serum response factor) family of transcription factors (Yu et al., 1992; Naya and Olson, 1999). MEF2 ... MEF2 is clearly not the only important transcription factor in neuronal differentiation, but it may represent a branch point in ... 1993) MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex. Proc Natl Acad Sci ... 1997) A dominant-negative form of transcription factor MEF2 inhibits myogenesis. J Biol Chem 272:33271-33278. ...
more infohttp://www.jneurosci.org/content/28/26/6557.long
SMART: MADS domain annotation  SMART: MADS domain annotation
MEF2A bound to DNA reveals a completely folded MADS-box/MEF2 domain that recognizes DNA and recruits transcription co-factors. ... The human serum response factor is a transcription factor belonging to the MADS domain protein family with members ... a Drosophila trachea development factor; the MEF2 family of myocyte-specific enhancer factors; and the Agamous and Deficiens ... Complex of the DNA binding core domain of the transcription factor MEF2A with a 20mer oligonucleotide. ...
more infohttp://smart.embl.de/smart/do_annotation.pl?DOMAIN=MADS&START=1&END=60&E_VALUE=3.15e-34&TYPE=SMART&BLAST=MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASS
RCSB PDB - Protein Feature View 









 - Myocyte-specific enhancer factor 2B - Q02080 (MEF2B HUMAN)  RCSB PDB - Protein Feature View - Myocyte-specific enhancer factor 2B - Q02080 (MEF2B HUMAN)
Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription. ... Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific ...
more infohttp://www.rcsb.org/pdb/protein/Q02080
MEF2C - Myocyte-specific enhancer factor 2C - Sus scrofa (Pig) - MEF2C gene & protein  MEF2C - Myocyte-specific enhancer factor 2C - Sus scrofa (Pig) - MEF2C gene & protein
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific ... Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific ... transcription factor activity, sequence-specific DNA binding Source: UniProtKB. *transcription regulatory region DNA binding ... RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: UniProtKB ...
more infohttp://www.uniprot.org/uniprot/A4UTP7
Most recent papers in the shared collection Parkinsons Disease & NIR | Read by QxMD  Most recent papers in the shared collection Parkinsons Disease & NIR | Read by QxMD
... induced neurotoxicity in PC12 cells was achieved through the activation of transcription factor myocyte enhancer factor 2D ( ... MEF2D), as evidenced by the fact that SU4312 stimulated myocyte enhancer factor 2 (MEF2) transcriptional activity and prevented ... The study aimed to uncover which factor between rigidity and bradykinesia is more associated with the reduction of arm and leg ... it remains uncertain which factor is more responsible for the decrease of arm and leg swings. ...
more infohttps://www.readbyqxmd.com/shared-collection/7702
archive-com.com: cell-research.com - Cell Research  archive-com.com: cell-research.com - Cell Research
... binding factor 2A MEF2A upregulated the expression of Id1 and Id2 and inhibited the transcriptional activity of MyoD and MEF2 ... 200031 China Correspondence Jianguo Song Tel 86 21 54921167 E mail jgsong sibs ac cn The forkhead box transcription factor A2 ... associated with MEF2 and repressed its transcriptional activity which could account for the OSM mediated repression of MEF2 ... 200433 China Correspondence Cheng He Tel 86 21 65515200 E mail chenghe smmu edu cn Glial cell line derived neurotrophic factor ...
more infohttp://archive-com.com/com/c/cell-research.com/2016-02-14_7510755_81/Cell_Research/
Functional and genomic analysis of MEF2 transcription factors in neural development  Functional and genomic analysis of MEF2 transcription factors in neural development
The MEF2 family of transcription factors (TFs) plays many essential roles in neural development; however, the mechanisms of ... Functional and genomic analysis of MEF2 transcription factors in neural development. Doctoral dissertation, Harvard University. ... We find that one MEF2 family member in particular, MEF2D, is an essential regulator of the development and function of retinal ... CRX recruits MEF2D away from canonical MEF2 binding sites by promoting MEF2D binding to retina-specific enhancers that lack a ...
more infohttps://dash.harvard.edu/handle/1/13070059
Inhibition of Myogenic bHLH and MEF2 Transcription Factors by the bHLH Protein Twist | Science  Inhibition of Myogenic bHLH and MEF2 Transcription Factors by the bHLH Protein Twist | Science
The myogenic basic helix-loop-helix (bHLH) and MEF2 transcription factors are expressed in the myotome of developing somites ... Inhibition of Myogenic bHLH and MEF2 Transcription Factors by the bHLH Protein Twist ... Inhibition of Myogenic bHLH and MEF2 Transcription Factors by the bHLH Protein Twist ... Inhibition of Myogenic bHLH and MEF2 Transcription Factors by the bHLH Protein Twist ...
more infohttp://science.sciencemag.org/content/272/5267/1476?ijkey=4dd848fc5c5655346415c4cc13acce47f5576231&keytype2=tf_ipsecsha
MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex. | PNAS  MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex. | PNAS
We have cloned cDNA encoding a human transcription factor that belongs to the MEF2 (myocyte-specific enhancer-binding factor 2 ... MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex.. D Leifer, D Krainc, Y T ... This factor, which we have named MEF2C, binds specifically to the MEF2 element and activates transcription via this element. ... MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex. ...
more infohttps://www.pnas.org/content/90/4/1546?ijkey=c1736a7e618608aa0f6c025fe0375a8040fd5197&keytype2=tf_ipsecsha
Regulation of the MEF2 Family of Transcription Factors by p38 | Molecular and Cellular Biology  Regulation of the MEF2 Family of Transcription Factors by p38 | Molecular and Cellular Biology
Regulation of the MEF2 Family of Transcription Factors by p38. Ming Zhao, Liguo New, Vladimir V. Kravchenko, Yutaka Kato, ... Regulation of the MEF2 Family of Transcription Factors by p38. Ming Zhao, Liguo New, Vladimir V. Kravchenko, Yutaka Kato, ... Regulation of the MEF2 Family of Transcription Factors by p38. Ming Zhao, Liguo New, Vladimir V. Kravchenko, Yutaka Kato, ... Regulation of the MEF2 Family of Transcription Factors by p38 Message Subject (Your Name) has forwarded a page to you from ...
more infohttps://mcb.asm.org/content/19/1/21/article-info
The transcription factor Mef2 is required for normal circadian behavior in Drosophila. - Semantic Scholar  The transcription factor Mef2 is required for normal circadian behavior in Drosophila. - Semantic Scholar
We found that Mef2 is normally produced in all adult clock neurons and that Mef2 overexpression in clock neurons leads to long ... Knocking down Mef2 expression via RNAi or expressing a repressor form of Mef2 caused flies to lose circadian behavioral rhythms ... while Mef2 knockdown strongly dampens molecular rhythms. Thus, a normal level of Mef2 activity is required in clock neurons to ... Here, we describe a role for Mef2 in the Drosophila pacemaker neurons that regulate circadian behavioral rhythms. ...
more infohttps://www.semanticscholar.org/paper/The-transcription-factor-Mef2-is-required-for-in-Blanchard-Collins/62e78e3e108a78af29578298a301bbfd10f36476
Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors | PNAS  Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors | PNAS
Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors. J F Martin, J J ... Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors ... Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors ... Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors ...
more infohttps://www.pnas.org/content/90/11/5282?ijkey=24c4309b2681b345a52e270673d9ce12bcc3e511&keytype2=tf_ipsecsha
RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription...  RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription...
... the up-regulation of the FoxM1 transcription factor and the misexpression of the neural progenitor transcription factors Six6 ... implication of MEF2 and FOXM1 transcription factors. Plos One , 5 (1). Art no.e8699 . ISSN 1932-6203 ... RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription ... In the absence of IGF-I, nuclear levels of MEF2 were diminished, indicating less transcriptional MEF2 activity. By contrast, ...
more infohttp://eprints.whiterose.ac.uk/10363/
Patent US7747389 - Scoring system for the prediction of cancer recurrence - Google Patents  Patent US7747389 - Scoring system for the prediction of cancer recurrence - Google Patents
... reverse transcription polymerase-chain reaction (hereinafter referred to as RT-PCR) to examine the expression of at least 2 or ... MADS/MEF2-family transcription factor (MEF2C), HUMLUCA19 Human cosmid clone LUCA19 from 3p21.3, DEAD-box protein p72, vimentin ... MADS/MEF2-family transcription factor (MEF2C), HUMLUCA19 Human cosmid clone LUCA19 from 3p21.3, DEAD-box protein p72, vimentin ... Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma, ...
more infohttp://www.google.com/patents/US7747389?dq=6,064,942
Activity-dependent regulation of inhibitory synapse development by Npas4 - Semantic Scholar  Activity-dependent regulation of inhibitory synapse development by Npas4 - Semantic Scholar
Here we report the identification of a transcription factor, Npas4, that plays a role in the development of inhibitory synapses ... Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number.. *Steven W. Flavell, ... Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF ... The transcription factor Npas4 contributes to adolescent development of prefrontal inhibitory circuits, and to cognitive and ...
more infohttps://www.semanticscholar.org/paper/Activity-dependent-regulation-of-inhibitory-synapse-Lin-Bloodgood/992aeff798e47c8165502bc72edac8d1e72b5e47
HDAC4 - Wikipedia  HDAC4 - Wikipedia
... and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor ... transcription corepressor activity. • histone deacetylase activity. • zinc ion binding. • transcription factor binding. • ... activating transcription factor binding. • metal ion binding. • protein binding. • transcription regulatory region DNA binding ... cellular response to tumor necrosis factor. • positive regulation of sequence-specific DNA binding transcription factor ...
more infohttps://en.wikipedia.org/wiki/HDAC4
MAPK14 - Wikipedia, la enciclopedia libre  MAPK14 - Wikipedia, la enciclopedia libre
de 1999). «Regulation of the MEF2 family of transcription factors by p38». Mol. Cell. Biol. (UNITED STATES) 19 (1): 21-30. ISSN ... de 1999). «Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors». Mol. Cell. Biol. (UNITED STATES) ... de 2001). «Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated ...
more infohttps://es.wikipedia.org/wiki/MAPK14
Frontiers | The Transcriptional Regulation of Germinal Center Formation | Immunology  Frontiers | The Transcriptional Regulation of Germinal Center Formation | Immunology
This review gives an overview of the transcription factors that have been linked to the generation of GCs, and of their roles ... This review gives an overview of the transcription factors that have been linked to the generation of GCs, and of their roles ... MEF2 transcription factors: developmental regulators and emerging cancer genes. Oncotarget (2016) 7:2297-312. doi: 10.18632/ ... Transcription factors that are downstream of the BCR, such as the transcription coactivator OBF1 (a.k.a. OCA-B, or Bob1), a B ...
more infohttps://www.frontiersin.org/articles/10.3389/fimmu.2018.02026/full
MKK6 | SpringerLink  MKK6 | SpringerLink
Neuronal activity-dependent cell survival mediated by transcription factor MEF2. Science. 1999;286(5440):785-90.CrossRefPubMed ... Regulation of the MEF2 family of transcription factors by p38. Mol Cell Biol. 1999;1:21-30.CrossRefGoogle Scholar ... Participation of the Mef2c transcription factor. J Biol Chem. 1999;274(8):5193-200.CrossRefPubMedGoogle Scholar ... Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE ...
more infohttps://link.springer.com/referenceworkentry/10.1007/978-3-319-67199-4_622
Frontiers | Preeclampsia-Associated Alteration of DNA Methylation in Fetal Endothelial Progenitor Cells | Cell and...  Frontiers | Preeclampsia-Associated Alteration of DNA Methylation in Fetal Endothelial Progenitor Cells | Cell and...
... represents an independent risk factor for cardiovascular disease. Our previous research shows a diminished function of fetal ... represents an independent risk factor for cardiovascular disease. Our previous research shows a diminished function of fetal ... 2016). MEF2 transcription factors are key regulators of sprouting angiogenesis. Genes Dev. 30, 2297-2309. doi: 10.1101/gad. ... Li, L., Rubin, L. P., and Gong, X. (2018). MEF2 transcription factors in human placenta and involvement in cytotrophoblast ...
more infohttps://www.frontiersin.org/articles/10.3389/fcell.2019.00032/full
Plus it  Plus it
2006) Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311:1008-1012. ... 2008) MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function ... Recent studies have demonstrated that transcriptional regulators, such as the MEF2 (myocyte enhancer factor 2) family and NPAS4 ... suggesting that not only transcription factors but also epigenetic mechanisms play crucial roles in the development of synaptic ...
more infohttp://www.jneurosci.org/content/29/25/8288
Satellite cells  Satellite cells
MEF2 family transcription factors can also promote myogenic differentiation. There is also research indicating that satellite ... Activated satellite cells express myogenic transcription factors, such as MyoD and Myf5. They also begin expressing muscle- ... Satellite cells are regulated by myogenic regulatory factors, such as MyoD, Myf5, myogenin, and MRF4. ... via the application of osteogenic bone morphogenetic proteins or transforming growth factor-beta. ...
more infohttps://www.bionity.com/en/encyclopedia/Satellite_cells.html
Life Sciences Faculty - Suzanne Paradis  Life Sciences Faculty - Suzanne Paradis
Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number.' Science 311: 1008-1012. ...
more infohttp://www.bio.brandeis.edu/faculty/paradis.html
The AMEDEO Literature Guide  The AMEDEO Literature Guide
Essential control of early B-cell development by Mef2 transcription factors.. Blood. 2016;127:572-81.. PubMed Text format ... Runx transcription factors in the development and function of the definitive hematopoietic system.. Blood. 2017;129:2061-2069. ... The GATA factor revolution in hematology.. Blood. 2017;129:2092-2102.. PubMed Text format Abstract available. *PORCHER C, ... Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell ...
more infohttp://amedeo.com/medicine/stc/blood.htm
The Molecular Bases of Training Adaptation | SpringerLink  The Molecular Bases of Training Adaptation | SpringerLink
Regulation of the MEF2 family of transcription factors by p38. Mol Cell Biol 1999; 19 (1): 21-30PubMedGoogle Scholar ... Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) ... Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 2004; ... Mitochondrial transcription factor A and respiratory complex IV increase in response to exercise training in humans. Pflugers ...
more infohttps://link.springer.com/article/10.2165%2F00007256-200737090-00001