Signal Transduction | Profiles RNS
Light Signal Transduction. *MAP Kinase Signaling System. *Mechanotransduction, Cellular. *Second Messenger Systems ... Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is ... Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the ... In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, ...https://profiles.uchicago.edu/profiles/display/35135
Browsing UT Southwestern Electronic Theses and Dissertations by Subject "MAP Kinase Signaling System"
... 0-9. A. B. C. D. E. F. G ... The RAF/MEK/MAP Kinase signal transduction cascade is the most extensively studied MAPK pathway that mediates diverse cellular ... One of the major functions of kinases in biological systems is the relay of signal from an effector to a downstream target. ... Kinases are regulated by a diversity of mechanisms, both internal and external to the kinase. When ... ...http://repositories.tdl.org/utswmed-ir/handle/2152.5/203/browse?value=MAP+Kinase+Signaling+System&type=subject
Journal of Business Ethics | Submission guidelines
Better keywords: neurodegenerative diseases; CA1 region, hippocampal; okadaic acid; neurotoxins; MAP kinase signaling system; ... This system supports a wide range of submission file formats: for manuscripts - Word, WordPerfect, RTF, TXT, and LaTex; for ... A notice of suspected transgression of ethical standards in the peer review system may be included as part of the author's and ... Our online manuscript submission and review system offers authors the option to track the progress of the review process of ...https://www.springer.com/journal/10551/submission-guidelines
Center for Theoretical & Mathematical Sciences » People
MAP Kinase Signaling System • Mathematics • Medial Forebrain Bundle • Melanins • Metabolic Detoxication, Drug • Metabolic ... Wheeler, DE; Nijhout, HF, A perspective for understanding the modes of juvenile hormone action as a lipid signaling system., ... Central Nervous System • Chemotactic Factors • Child • Child, Preschool • Choline • Chromosome Mapping • Classification • ... Nijhout, HF; Berg, AM; Gibson, WT, A mechanistic study of evolvability using the mitogen-activated protein kinase cascade., ...http://fds.duke.edu/db/aas/math/ctms/faculty/hfn
Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells.
MAP Kinase Signaling System*. Male. Middle Aged. Nuclear Proteins / metabolism*. Transfection. p38 Mitogen-Activated Protein ... Intracellular Signaling Peptides and Proteins / metabolism*. JNK Mitogen-Activated Protein Kinases / metabolism*. Liver ... EC 188.8.131.52/JNK Mitogen-Activated Protein Kinases; EC 184.108.40.206/p38 Mitogen-Activated Protein Kinases ... 11560959 - Signaling through cd28 and ctla-4 controls two distinct forms of t cell anergy.. 12072179 - Investigating the ...http://www.biomedsearch.com/nih/Gadd45-alpha-gamma-utilize-p38/19048389.html
GPER | Cancer Genetics Web
MAP Kinase Signaling System. *Insulin-Like Growth Factor I. *Cell Culture Techniques ... extracellular signal-regulated protein kinases) signaling pathway. These four estrogen receptors were detected by Western blot ... We evaluated the role of GPER-1 in the mitogen-activated protein kinase (MAPK) signaling pathway using Western blot analysis. ... the Notch signaling pathway and the mitogen-activated protein kinases (MAPK) pathway. In this chapter we will present some of ...http://www.cancerindex.org/geneweb/GPER.htm
Alternative splicing results in RET isoforms with distinct trafficking properties.
... and enteric nervous systems and the kidneys, as well as for maintenance of adult midbrain dopaminergic neurons. RE ... RET encodes a receptor tyrosine kinase that is essential for spermatogenesis, development of the sensory, sympathetic, ... MAP Kinase Signaling System. Molecular Sequence Data. Protein Isoforms / genetics, metabolism. Protein Processing, Post- ... most notably phosphoinositide 3-kinase/AKT, extracellular-signal regulated kinase (ERK)/mitogen-activated protein (MAP) kinase ...http://www.biomedsearch.com/nih/Alternative-splicing-results-in-RET/22875993.html
BCK1 and MPK1 are required for repolarization of the ac | Open-i
MAP Kinase Signaling System. *Membrane Glycoproteins/genetics/metabolism. *Membrane Proteins/metabolism. *Polymers ... 1998b) suggested that the PKC1-activated MAP kinase pathway might be required for repolarization. To investigate this further, ... 1998b) suggested that the PKC1-activated MAP kinase pathway might be required for repolarization. To investigate this further, ... Thus, the PKC1-activated MAP kinase cascade is required for repolarization rather than depolarization of cell growth. ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2164985_JCB9905001.f4&req=4
Effect of β1-integrin-uPAR complex disruption and su | Open-i
MAP Kinase Signaling System*. *Neoplasms/enzymology/metabolism/pathology*. *Protein-Serine-Threonine Kinases* ... Compared with uPAR-rich tumorigenic cells, the basal level of active extracellular regulated kinase (ERK) was four to sixfold ... Compared with uPAR-rich tumorigenic cells, the basal level of active extracellular regulated kinase (ERK) was four to sixfold ... Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2164973_JCB9907025.f7&req=4
Effect of different tumor necrosis factor (TNF) reactive agents on reverse signaling of membrane integrated TNF in monocytes -...
MAP Kinase Signaling System/drug effects. MESH. Membrane Proteins/metabolism. MESH. Monocytes/metabolism. MESH. ... Reverse signaling of transmembrane TNF (mTNF) contributes to the versatility of this cytokine superfamily. Previously, we could ... Reverse signaling of transmembrane TNF (mTNF) contributes to the versatility of this cytokine superfamily. Previously, we could ... Effect of different tumor necrosis factor (TNF) reactive agents on reverse signaling of membrane integrated TNF in monocytes ...https://epub.uni-regensburg.de/14433/
Victor E Velculescu - Research Output - Johns Hopkins University
MAP Kinase Signaling System Drug Combinations Correction to: persistent mutant oncogene specific T cells in two patients ...https://jhu.pure.elsevier.com/en/persons/victor-e-velculescu/publications/
ZFIN Publication: Li et al., 2012
MAP Kinase Signaling System. *Male. *Oncogenes*/drug effects. *Receptor Protein-Tyrosine Kinases/genetics* ... Using the Tet-on system for liver-specific expression of fish oncogene xmrk, a hyperactive version of epidermal growth factor ...http://zfin.org/ZDB-PUB-110907-29
Welcome to LibAge, the ageing reference resource
Entries tagged MAP Kinase Signaling System/genetics (3). Sort:. Number of citations. Author. Title. Year. PubMed ID. ... and mitogen-activated protein kinase pathway." Cancer Res. 67(10):4956-4964 (PubMed) ...http://libage.ageing-map.org/entries/tags/9504/
"TLR2- and TLR4-mediated signals determine attenuation or augmentation " by Shilpa A. Oak, Pranoti Mandrekar et al.
IL-1R-associated kinase (IRAK)-1 activity was reduced by alcohol in TLR4, but it was augmented in TLR2- plus TLR4-stimulated ... These results suggest that acute alcohol attenuates TLR4-induced inflammation via inhibition of IRAK-1 and ERK1/2 kinases and ... Thus, the complexity of TLR-mediated signals may determine attenuation or augmentation of inflammatory responses by acute ... Most pathogens express ligands for multiple TLRs that share common downstream signaling. In this study, we investigated the ...https://escholarship.umassmed.edu/oapubs/1085/
A Phase II Study of MS-275, in Combination With GM-CSF Treating Relapsed and Refractory Myeloid Malignancies
Costello syndrome shows early phenotypic overlap with other disorders that involve MAP KINASE SIGNALING SYSTEM (e.g., NOONAN ... This Study aims to evaluate the efficacy and safety of CDA-2 in the treatment of International Prognostic Scoring System (IPSS ... An autosomal dominant aneurysm with multisystem abnormalities caused by increased TGF-BETA signaling due to mutations in type I ...https://www.bioportfolio.com/resources/trial/100087/A-Phase-II-Study-of-MS-275-in-Combination-With-GM-CSF.html
Tocilizumab for the Treatment of Refractory Behcet's Uveitis
Costello syndrome shows early phenotypic overlap with other disorders that involve MAP KINASE SIGNALING SYSTEM (e.g., NOONAN ... An autosomal dominant aneurysm with multisystem abnormalities caused by increased TGF-BETA signaling due to mutations in type I ...https://www.bioportfolio.com/resources/trial/209314/Tocilizumab-for-the-Treatment-of-Refractory-Behcets-Uveitis.html
Haojie Huang, PhD - Research Output - Mayo Clinic
MAP Kinase Signaling System Colorectal Neoplasms Neoplastic Stem Cells Xenograft Model Antitumor Assays ... Androgen receptor signaling in castration resistant prostate cancer. Zhao, Y., Tindall, D. J. & Huang, H., Jan 1 2016, Managing ... Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in PTEN- or SPOP-mutated prostate cancer. Yan, Y., An, J., Yang ...https://mayoclinic.pure.elsevier.com/en/persons/haojie-huang/publications/
... modulates oxidative stress and inflammation-associated development of coronary artery spasm via a p38 MAP-kinase signaling- ... MAP Kinase Signaling System Nicotinic Receptors Spasm p38 Mitogen-Activated Protein Kinases ...https://tmu.pure.elsevier.com/en/persons/ming-yow-hung-2
"Pathological axonal death through a MAPK cascade that triggers a local" by Jing Yang, Zhuhao Wu et al.
Further, MKK4, a key component in the Sarm1-MAPK pathway, is antagonized by AKT signaling, which modulates the degenerative ... Our results reveal a regulatory mechanism that integrates distinct signals to instruct pathological axon degeneration. ... Using traumatic injury as a model, we systematically investigate mitogen-activated protein kinase (MAPK) families and delineate ... response by limiting activation of downstream JNK signaling. ... MAP Kinase Kinase 4; *MAP Kinase Signaling System; Mice; ...https://escholarship.umassmed.edu/davis/13/
Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells<...
Thus ErbB2 is a critical component of IL-6 signalling through the MAP kinase pathway. These data show how a cytokine receptor ... Thus ErbB2 is a critical component of IL-6 signalling through the MAP kinase pathway. These data show how a cytokine receptor ... Thus ErbB2 is a critical component of IL-6 signalling through the MAP kinase pathway. These data show how a cytokine receptor ... Thus ErbB2 is a critical component of IL-6 signalling through the MAP kinase pathway. These data show how a cytokine receptor ...https://ucdavis.pure.elsevier.com/en/publications/requirement-of-erbb2-for-signalling-by-interleukin-6-in-prostate-