Proteome-scale profiling reveals MAFF and MAFG as two novel key transcription factors involved in palmitic acid-induced...
Overexpression of MAFG or MAFF in HUVECs significantly inhibited PA-induced early apoptosis. We identified MAFF and MAFG as ... The purpose of our study was to use a new generation high-throughput transcription factor (TF) detection method to identify ... of the 51 TFs, v-maf musculoaponeurotic fibrosarcoma oncogene family protein G (MAFG) and v-maf musculoaponeurotic fibrosarcoma ... Vascular endothelial cell apoptosis is the leading risk factor of atherosclerosis (AS). ...
Small Maf - Wikipedia
Agrawal, SA (2015). "Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non- ... Knockout mouse studies have shown that Mafg knockout mice display mild ataxia. Mafg and Mafk mutant mice (Mafg−/−::Mafk+/−) ... "Interaction of the CNC-bZIP factor TCF11/LCR-F1/Nrf1 with MafG: binding-site selection and regulation of transcription. Nucleic ... sMafs form homodimers by themselves and heterodimers with other specific bZIP transcription factors, such as transcription ...
Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids | Communications Biology
Kannan, M. B., Solovieva, V. & Blank, V. The small MAF transcription factors MAFF, MAFG, and MAFK: current knowledge and ... The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord. Neuron 52, 953-968 (2006). ... Ding, Q., Joshi, P. S., Xie, Z. H., Xiang, M. & Gan, L. BARHL2 transcription factor regulates the ipsilateral/contralateral ... The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nat. Commun. 6, 8479 (2015). ...
GSE14415 INDUCED TREG VS FOXP3 KO INDUCED TREG IL2 CULTURE DN
MAFG. 4097. MAFG. MAF bZIP transcription factor G.... MAML2. 84441. MAML2. mastermind like transcriptional.... ... TFT: Transcription Factor Targets TFT:GTRD: GTRD TFT:TFT_LEGACY: TFT_Legacy C4: Computational CGN: Cancer Gene Neighborhoods CM ... The role of the regulatory T cell transcription factor Foxp3 in shaping the transcriptosomes of natural and induced regulatory ... KLF transcription factor 12 [So.... KLF3. 51274. KLF3. KLF transcription factor 3 [Sou.... ...
DeCS 2020 - June 23, 2020 version
MafG Transcription Factor MafK Protein use MafK Transcription Factor MafK Transcription Factor ... Macrophage Chemotactic Factors use Chemotactic Factors Macrophage Colony Stimulating Factor Receptors use Receptor, Macrophage ... Macrophage Migration Inhibition Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Inhibition Test use ... Macrophage Migration Inhibitory Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Test use Cell ...
DeCS 2018 - July 31, 2018 version
MafG Transcription Factor MafK Protein use MafK Transcription Factor MafK Transcription Factor ... Macrophage Chemotactic Factors use Chemotactic Factors Macrophage Colony Stimulating Factor Receptors use Receptor, Macrophage ... Macrophage Migration Inhibition Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Inhibition Test use ... Macrophage Migration Inhibitory Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Test use Cell ...
DeCS 2018 - July 31, 2018 version
MafG Transcription Factor MafK Protein use MafK Transcription Factor MafK Transcription Factor ... Macrophage Chemotactic Factors use Chemotactic Factors Macrophage Colony Stimulating Factor Receptors use Receptor, Macrophage ... Macrophage Migration Inhibition Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Inhibition Test use ... Macrophage Migration Inhibitory Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Test use Cell ...
DeCS 2017 - July 04, 2017 version
MafG Transcription Factor MafK Protein use MafK Transcription Factor MafK Transcription Factor ... Macrophage Chemotactic Factors use Chemotactic Factors Macrophage Colony Stimulating Factor Receptors use Receptor, Macrophage ... Macrophage Migration Inhibition Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Inhibition Test use ... Macrophage Migration Inhibitory Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Test use Cell ...
DeCS 2018 - July 31, 2018 version
MafG Transcription Factor MafK Protein use MafK Transcription Factor MafK Transcription Factor ... Macrophage Chemotactic Factors use Chemotactic Factors Macrophage Colony Stimulating Factor Receptors use Receptor, Macrophage ... Macrophage Migration Inhibition Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Inhibition Test use ... Macrophage Migration Inhibitory Factors use Macrophage Migration-Inhibitory Factors Macrophage Migration Test use Cell ...
Integration of single-cell regulon atlas and multi-omics data for prognostic stratification and personalized treatment...
... superfamily and are basic leucine zipper transcription factors. MafG, MafF and MafK belongs to small Mafs (approximately 150- ... The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target ... The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors. Development. 2012; ... ZFHX4 is a transcription factor and has been shown to be associated with the maintenance of tumor-initiating cells in ...
JASPAR -
MAFG::NFE2L1 - MA0089.1 - profile summary
JASPAR is the largest open-access database of curated and non-redundant transcription factor (TF) binding profiles from six ... JASPAR is an open-access database of curated, non-redundant transcription factor (TF) binding profiles stored as position ... MAFG::NFE2L1. Gallus gallus Maf-related factors::Jun-related factors. Basic leucine zipper factors (bZIP)::Basic leucine zipper ... Basic leucine zipper factors (bZIP)::Basic leucine zipper factors (bZIP). Family: Maf-related factors::Jun-related factors. ...
Pesquisa | Biblioteca Virtual em Saúde - BRASIL
... and MAF BZIP transcription factor G (MafG), in neurons was suppressed at 4 weeks and upregulated at 8 weeks following spinal ... Emerging evidence indicates that transcription factor 7 (TCF7) is the key downstream functional molecule of Wnt/ß-catenin ... After including multiple factors, right coronary artery (RCA), LVEF, and reservoir strain were still risk factors for new-onset ... In model 3, RCA, LVEF, LVEDVi, and booster strain were still risk factors for new-onset AF. Model 2 has a stronger ...
Publications 2021<...
Interaction of miR-146a-5p with oxidative stress and inflammation in complications of type 2 diabetes mellitus in male rats:...
The level of lipid peroxidation along with metabolic and inflammatory factors significantly increased and the antioxidant ... TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner. ... Nrf2-MafG heterodimers contribute globally to anti-oxidant and metabolic networks. Nucleic Acids Res 2012;40:10228-10239.. 67. ... Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway. Cell Signal 2011;23:883-892.. 66. Hirotsu Y, Katsuoka ...
Gene Q96RI1 | Protein NR1H4 - Overview | canSAR Black
Ligand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDC... , canSAR Black ... Activates transcription of the repressor MAFG (involved in regulation of BA synthesis) (By similarity). Activates transcription ... Ligand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, ... Ligand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholic acid, ...
Ex vivo generation of platelet products from human iPS cells | Inflammation and Regeneration | Full Text
... macrophage migration inhibitory factor (MIF), insulin growth factor binding protein 2 (IGFBP2), and nardilysin (NRDC), enhanced ... Interestingly, three soluble factors released from imMKCLs in the turbulent flow condition, ... that depends on the exogenous expression of three transcription factors, GATA1, FLI1, and TAL1. These factors are introduced ... directly converted mouse and human fibroblasts into MK progenitors by genetically introducing three factors, NFE2, MAFG, and ...
High Mobility Group B Proteins, Their Partners, and Other Redox Sensors in Ovarian and Prostate Cancer
HMGB1 interacts differentially with members of the REL family of transcription factors (RELA/P65, c-REL, RELB, P50/NF-κB1, and ... F. Katsuoka, H. Motohashi, J. D. Engel, and M. Yamamoto, "Nrf2 transcriptionally activates the mafG gene through an antioxidant ... In the nucleus, HMGB proteins interact with a number of transcription factors, among them tumour suppressors like P53 [51-53] ... E.-J. Tan, S. Thuault, L. Caja, T. Carletti, C.-H. Heldin, and A. Moustakas, "Regulation of transcription factor twist ...
Dual-negative expression of Nrf2 and NQO1 predicts superior outcomes in patients with non-small cell lung cancer | Oncotarget
NF-E2-related factor 2 (Nrf2) is a member of the CapnCollar/basic leucine zipper (CNC-bZIP) transcription factor family. ... Hirotsu Y, Katsuoka F, Funayama R, Nagashima T, Nishida Y, Nakayama K, Engel JD, Yamamoto M. Nrf2-MafG heterodimers contribute ... Compared with mono-factor Nrf2 or NQO1, the co-factor Nrf2 and NQO1 was more useful in predicting overall survival (P = 0.020) ... Nrf2 is a predictive factor for overall survival (OS) (P = 0.011), and NQO1 is a predictive factor for disease free survival ( ...
Frontiers | Unbiased transcriptome mapping and modeling identify candidate genes and compounds of osteoarthritis
2021). Transcription factor MAFF (MAF basic leucine zipper transcription factor F) regulates an atherosclerosis relevant ... Katsuoka, F., and Yamamoto, M. (2016). Small maf proteins (MafF, MafG, MafK): History, structure and function. Gene 586, 197- ... 2018). Identification of transcription factors responsible for dysregulated networks in human osteoarthritis cartilage by ... MAFF, one of the basic region leucine zipper (bZIP)-type transcription factors, participates in transcriptional activation or ...
Viruses | Free Full-Text | RNA-Sequencing Analysis of 5' Capped RNAs Identifies Many New Differentially Expressed Genes in...
A number of members of the Sp1-like/KLF family of transcription factors (SP1, SP5, KLF10, KLF11, KLF13, KLF15, KLF16, KLF3, ... They include FGF2 and FZD9 (both 4-fold increase), CEBPB (2.7-fold increase), LNK, MAFG and TFEB (all 2.5-fold increase), PKD1 ... The AT-hook transcription factors, of which AKNA is a member, repress or activate gene networks controlling inflammation, ... Figure 5. Increased expression of AT-hook transcription factor (AKNA, Chr 9, − strand) during acute HCV infection. (A) RNA ...
HDAC3 synthetic lethal interactions - Slorth
Neurogen Drugs
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach. Pharmacol. Rev. 2018, 70 ( ... M.; De Castro, J.; Ibanez de Caceres, I. MAFG Is a Potential Therapeutic Target to Restore Chemosensitivity in Cisplatin- ... An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti- ... and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators. J. Med. Chem. 2016, 59 (21), 9967-9973. https://doi.org/10.1021/acs ...
NCOR1 synthetic lethal interactions - Slorth
Transcriptome profiling and co-expression network analysis of lncRNAs and mRNAs in colorectal cancer by RNA sequencing | BMC...
Reverse transcription quantitative polymerase chain reaction (RT-qPCR) was used to validate the expression pattern of ... RT-qPCR showed that BBOX1-AS1, MIR503HG, SLCO4A1-AS1, MAFG-AS1, MIR4435-1HG were significantly up-regulated compared with ... Reverse transcription quantitative polymerase chain reaction (RT-qPCR) was used to validate the expression pattern of ... miRNA-27b targets vascular endothelial growth factor C to inhibit tumor progression and angiogenesis in colorectal cancer. PLoS ...
View source for FFCP PHASE1:Mm9::chr11:120494983..120494990,- - resource browser
DNA Methylation in Cancer and Aging | Cancer Research | American Association for Cancer Research
... foci of de novo and demethylation events that appear to encompass putative enhancer sequences harboring transcription factor- ... The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG island methylator phenotype ... These targeted events are all mediated through cis-acting sequences and trans-acting factors that presumably recruit the ... factor that may influence the generation of abnormal DNA methylation patterns is oxygen stress, which has been shown to ...
SUMO3 and ATF3 Interaction - Wiki-Pi
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In ... MAFG MDM2 NFKB1 NUF2 PDX1 POLR3D SMAD3 SRA1 SS18L1 STAT1 SUMO1 SUMO3 SUV39H1 TP53 ZNF212 ... RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In ...
GTF2A1L and CSNK2A2 - Wiki-MPM
CEBPG and ATF3 - Wiki-MPM
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific. *DNA-binding Transcription Activator Activity, RNA ... MAFG NFKB1 NUF2 PDX1 POLR3D SH2D1A SMAD3 SRA1 SS18L1 STAT1 STAT3 SUV39H1 TP53 TP73 UBE2I ZNF212 ... DNA-binding Transcription Factor Activity, RNA Polymerase II-specific. *DNA-binding Transcription Repressor Activity, RNA ... Positive Regulation Of Transcription By RNA Polymerase II. *Regulation Of Transcription From RNA Polymerase II Promoter In ...
Publications | Dash Lab
Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes ... The master transcription factor SOX2, mutated in anophthalmia/microphthalmia, is post-transcriptionally regulated by the ... rRNA transcription is integral to liquid-liquid phase separation and maintenance of nucleolar structure. ...